Methyl chloride supplier

Name
Methyl chloride
EINECS 200-817-4
CAS No. 74-87-3
Article Data719
CAS DataBase
Density 0.895 g/cm³
Solubility
Melting Point -97 °C
Formula CH₃Cl
Boiling Point -24.2oC
Molecular Weight 50.4878
Flash Point -46oC
Transport Information UN 1993 3/PG 1
Appearance colourless gas with a minorly sweet odor
Safety 9-16-33
Risk Codes 12-40-48/20
Molecular Structure
Hazard Symbols F+,Xn,T,F
Synonyms chloromethane;
PSA 0.00000
LogP 0.85500

Synthetic route

: 1928-38-7
methyl 2,4-dichlorophenoxyacetate

A: 94-75-7
2,4-Dichlorophenoxyacetic acid

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With hydrogenchloride; zinc(II) chloride In water at 140℃; for 4h; Reagent/catalyst; Temperature;	A 99.6% B 98.1%

: 756-79-6
dimethyl methane phosphonate

A: 676-97-1
methylphosphonic acid dichloroanhydride

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With thionyl chloride; N-Formylpiperidine for 19h; Heating; various conditions and cactalasts investigated;	A 99.2% B n/a

: 54705-23-6
methyl o-(N-methylcarbamoyl)phenyl sulphoxide

A: 2527-66-4
2-methyl-1,2-benzisothiazole-3(2H)-one

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With thionyl chloride In tetrachloromethane for 5h; Heating;	A 99% B n/a

: [PdCl(N,N′-di-metyl-2,11-diaza[3,3](2,6)pyridinophane)(CH3)](2+)

: 56-34-8
tetraethylammonium chloride

A: 74-87-3
methylene chloride

: 1414791-67-5
[PdCl2(N,N-di-metyl-2,11-diaza[3,3](2,6)pyridinophane)]

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 1h; Mechanism; Darkness;	A 99% B 99%

...Expand

: 75-44-5
phosgene

: 104953-88-0
2,3-bis(dimethylamino)quinol-4-one

A: 74-87-3
methylene chloride

B: 104953-90-4
4-Dimethylamino-3-methyl-3H-oxazolo[4,5-c]quinolin-2-one

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 3h; Product distribution; Ambient temperature; aminoquinolones with COCl2;	A n/a B 98%
With triethylamine In dichloromethane for 3h; Ambient temperature;	A n/a B 98%

...Expand

: 79054-68-5
N-phenyl-2-(methylsulfinyl)benzamide

A: 2527-03-9
2-phenyl-1,2-benzisothiazolin-3-one

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane for 0.166667h; Heating;	A 98% B n/a

: 79054-66-3
N-Cyclohexyl-2-methanesulfinyl-benzamide

A: 74-87-3
methylene chloride

B: 2527-02-8
2-cyclohexyl-1,2-benzisothiazol-3(2H)-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A n/a B 98%

: 79054-69-6
2-Methanesulfinyl-N-p-tolyl-benzamide

A: 74-87-3
methylene chloride

B: 2514-30-9
2-(4-tolyl)-1,2-benzisothiazol-3-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A n/a B 98%

: 79054-67-4
N-Benzyl-2-methanesulfinyl-benzamide

A: 74-87-3
methylene chloride

B: 2514-36-5
2-benzylbenzo[d]isothiazol-3(2H)-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A n/a B 98%

: 79054-64-1
N-Isopropyl-2-methanesulfinyl-benzamide

A: 74-87-3
methylene chloride

B: 2-isopropyl-1,2-benzisothiazolin-3-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A n/a B 97%

: Cp(CO)2Re(CH3)2

A: tricarbonylcyclopentadienylrhenium

B: 74-87-3
methylene chloride

C: C5H5Re(CO)2(CH3)Cl

D: 75-36-5
acetyl chloride

E: 67-64-1
acetone

Conditions

Conditions	Yield
With tetrachloromethane; carbon monoxide In tetrachloromethane Irradiation (UV/VIS); Irradiation of complex at 350-380 nm under 20 atm of CO in CCl4;;	A 97% B 19% C <4 D 152 % E 6%

...Expand

: 75-09-2
dichloromethane

A: 74-87-3
methylene chloride

B: 75-10-5
Difluoromethane

C: 593-70-4
R32

D: 75-46-7
trifluoromethan

Conditions

Conditions	Yield
With hydrogen fluoride; antimony(III) fluoride; antimony pentafluoride at 5 - 100℃; under 12504.7 Torr;	A n/a B 96.9% C 3.08% D n/a
antimony pentafluoride	A n/a B 96.4% C 3.56% D n/a

...Expand

: 79054-63-0
N-Ethyl-2-methanesulfinyl-benzamide

A: 4299-06-3
2-Ethylbenzisothiazolin-3-on

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A 96% B n/a

: 32579-76-3
1-chloro-2,2,6,6-tetramethylpiperidine

A: 74-87-3
methylene chloride

B: 112269-97-3
2,2,6-trimethyl-2,3,4,5-tetrahydropyridine

Conditions

Conditions	Yield
With 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 80℃;	A 95% B 8.5 g

: 528-76-7
2,4-dinitrobenzenesulfenyl chloride

A: 74-87-3
methylene chloride

B: 2217-55-2
bis(2,4-dinitrophenyl) disulphide

C: 2363-23-7
methyl 2,4-dinitriophenyl sulfide

Conditions

Conditions	Yield
With tetramethylstannane; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 25℃; for 4h; Mechanism; other sulfenyl halides, other reagents: tetraethylstannane, hexamethyldistannane, tributylvinylstannane, tetracyclohexylstannane, tetraphenylstannane, cyclohexene, tetramethylgermane, other solvent: THF-d8;	A n/a B 95% C n/a

...Expand

: 7446-70-0
aluminium trichloride

: 100-66-3
methoxybenzene

A: 74-87-3
methylene chloride

B: dichloroaluminium phenoxide

Conditions

Conditions	Yield
In neat (no solvent) 1:1 mixt. was heated at 130°C for 6 h;	A 95% B n/a

...Expand

: {PdCl[Ind(Ph2P=S)2]}(nBu4N)

: 74-88-4
methyl iodide

A: 74-87-3
methylene chloride

: {PdI[Ind(Me)(Ph2P=S)2]}

C: 311-28-4
tetra-(n-butyl)ammonium iodide

Conditions

Conditions	Yield
In dichloromethane at 40℃; for 24h; Inert atmosphere;	A n/a B 95% C n/a

...Expand

: 3279-26-3
methyl dichlorophosphite

: 1495-26-7
trifluoromethaneselenenyl chloride

A: 74-87-3
methylene chloride

B: 77001-46-8
Se-trifluoromethylphosphorodichloridoselenoate

Conditions

Conditions	Yield
With antimonypentachloride at -10 - 5℃;	A n/a B 94%

...Expand

: 110-86-1
pyridine

: C6H12Cl2O2Pt

A: 74-87-3
methylene chloride

B: 1395411-03-6
cis-Cl(py)Pt(COMe)[C(OMe)(Me)]

Conditions

Conditions	Yield
In tetrahydrofuran-d8 at 55℃; for 2h;	A n/a B 93%

...Expand

: 67-56-1
methanol

: 31528-95-7
1-(1-naphthyl)-3-phenyl-2,2-dichloroaziridine

A: 74-87-3
methylene chloride

B: 115-10-6
Dimethyl ether

C: 7476-66-6
methyl 2-chloro-2-phenylethanoate

D: 3558-61-0
methyl 2-methoxy-2-phenylacetate

E: 552-46-5
1-naphthylamine hydrochloride

Conditions

Conditions	Yield
Product distribution; Heating;	A n/a B n/a C n/a D n/a E 91%

...Expand

: C6H12Cl2O2Pt

: 1112-67-0
tetrabutyl-ammonium chloride

A: 74-87-3
methylene chloride

B: 1395411-09-2
(n-Bu4NCl)[Cl2Pt(COMe)(C(OMe)(Me))]

Conditions

Conditions	Yield
In dichloromethane-d2 at 20℃; for 0.25h;	A n/a B 87%

...Expand

: 75-44-5
phosgene

: 104953-89-1
2,3-Bis-dimethylamino-1H-benzo[h]quinolin-4-one

A: 74-87-3
methylene chloride

B: 104953-91-5
12-Dimethylamino-17-methyl-17H-15-oxa-11,17-diaza-cyclopenta[a]phenanthren-16-one

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 3h; Ambient temperature;	A n/a B 85%

...Expand

: 57182-16-8
2,2,2-trichloro-N-methylacetimidoyl chloride

: 121-45-9
phosphorous acid trimethyl ester

A: 70795-51-6
C7H15Cl2NO6P2

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
In toluene for 2h; Heating;	A 84% B n/a

...Expand

: 13657-45-9
N-methyl-N-(methoxymethyl)-aniline

: 1079-66-9
chloro-diphenylphosphine

A: 74-87-3
methylene chloride

B: 76527-75-8
<(methylphenylamino)methyl>diphenylphosphine oxide

Conditions

Conditions	Yield
In tetrahydrofuran	A n/a B 83%

...Expand

: 57182-25-9
N-ethyl-2,2,2-trichloro-acetimidoyl chloride

: 121-45-9
phosphorous acid trimethyl ester

A: 74-87-3
methylene chloride

B: 70795-55-0
{2,2-Dichloro-1-[(dimethoxy-phosphoryl)-ethyl-amino]-vinyl}-phosphonic acid dimethyl ester

Conditions

Conditions	Yield
In toluene for 2h; Heating;	A n/a B 82%

...Expand

: 2136-81-4
3-chlorobenzotrichloride

: 756-79-6
dimethyl methane phosphonate

A: 74-87-3
methylene chloride

B: 2905-65-9
methyl 3-chlorobenzoate

C: methylphosphonic acid anhydride

Conditions

Conditions	Yield
at 180℃; for 53h;	A n/a B 81% C n/a

...Expand

: 2051-90-3
Dichlorodiphenylmethane

: 756-79-6
dimethyl methane phosphonate

A: 119-61-9
benzophenone

B: 74-87-3
methylene chloride

C: methylphosphonic acid anhydride

Conditions

Conditions	Yield
at 100 - 120℃; for 28h;	A 80% B n/a C 51%

...Expand

: 98-87-3
benzylidene dichloride

: 18632-46-7
Methyl Diisopropylphosphinate

A: 74-87-3
methylene chloride

B: 1112-15-8
diisopropylphosphoryl chloride

C: 100-52-7
benzaldehyde

D: 67949-89-7
diisopropylphosphinic anhydride

Conditions

Conditions	Yield
at 180℃; for 17h; Product distribution; Mechanism; other gem-dihalide: benzal bromide, other methyl esters of tetracoordinated phosphorus acids, various reactants ratio, other reaction temperature and time;	A n/a B n/a C 79.7% D 75%

...Expand

: 5216-25-1
4-chlorotrichloromethylbenzene

: 756-79-6
dimethyl methane phosphonate

A: 1126-46-1
Methyl 4-chlorobenzoate

B: 74-87-3
methylene chloride

C: methylphosphonic acid anhydride

Conditions

Conditions	Yield
at 180℃; for 53h;	A 79% B n/a C n/a

...Expand

: 79054-65-2
N-t-butyl-2-(methylsulphinyl)benzamide

A: 74-87-3
methylene chloride

B: 35159-95-6
2-(tert-butyl)benzo[d]isothiazol-3(2H)-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane for 1h; Ambient temperature;	A n/a B 77%
With thionyl chloride In dichloromethane Heating;	A n/a B 77%

: C18H42FSi3(1-)*Li(1+)

: 74-87-3
methylene chloride

: 1,1,3,3-tetra-tert-butyl-2-fluoro-1,2,3-trimethyl-trisilane

Conditions

Conditions	Yield
In tetrahydrofuran; hexane at 20℃;	100%

: 74-87-3
methylene chloride

: 3436-54-2
N,N’-bis[3-(dimethylamino)propyl]-1,4,5,8-naphthalenetetracarboxylic 1,8:4,5-diimide

: 83356-30-3
hexa-N-methyl-N,N'-[3,3'-(1,3,6,8-tetraoxo-1,3,6,8-tetrahydro-benzo[lmn][3,8]phenanthroline-2,7-diyl)-dipropyl]-bis-ammonium

Conditions

Conditions	Yield
In chloroform at 20℃; for 24h; Green chemistry;	100%

: 74-87-3
methylene chloride

: 111-77-3
2-(2-methoxyethoxy)ethyl alcohol

: 110-71-4
1,2-dimethoxyethane

Conditions

Conditions	Yield
With sodium hydroxide In water at 60℃;	99.8%

: 74-87-3
methylene chloride

: 753-73-1
dimethyltin dichloride

: 3086-29-1
trimethylsulfonium chloride

: 993-16-8
methyltin(IV) trichloride

Conditions

Conditions	Yield
tin(IV) chloride	99.7%

...Expand

: 74-87-3
methylene chloride

: 3-(2-chloro-5-(2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidine-1(2H)-yl)-4-fluorophenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid methyl ester

: C18H14ClF4N3O5

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane; sodium carbonate In ethyl acetate at 95 - 105℃; under 6750.68 Torr; for 11h; Autoclave;	99.2%

: 74-87-3
methylene chloride

: 103897-73-0
benzyl α-(N,N-dimethylamino)ethyl Boc-glutamate

: 103897-79-6
α-(γ-benzyloxy-Boc-glutamyl)choline chloride

Conditions

Conditions	Yield
In ethyl acetate; benzene for 168h; Ambient temperature;	99%

: 74-87-3
methylene chloride

: 101463-49-4
α-tert-butyl γ-(N,N-dimethylamino)ethyl Z-glutamate

: 101463-50-7
γ-(α-tert-butyloxy-Z-glutamyl)choline chloride

Conditions

Conditions	Yield
In ethyl acetate; benzene for 168h; Ambient temperature;	99%

: 1116-76-3
Tri-n-octylamine

: 74-87-3
methylene chloride

: 140-29-4
phenylacetonitrile

: 76574-43-1
2,3-dimethylphenylacetonitrile

Conditions

Conditions	Yield
With sodium hydroxide In water	99%

...Expand

: 240123-21-1
[(κ2-P,N)-2-(N,N-dimethylamino)ethyldiphenylphosphino]dimethylplatinum(II)

: 74-87-3
methylene chloride

: [(κ(2)-P,N)-Ph2PCH2CH2NMe2]PtMe3Cl

Conditions

Conditions	Yield
In benzene-d6 all manipulations under Ar atm.; MeCl bubbled through soln. of Pt compd., then heated to .60°C for 24 h; crystd. from benzene, elem. anal.;	99%
In benzene-d6 all manipulations under Ar atm.; MeCl bubbled through soln. of Pt compd., then heated to .60°C for 12 h; crystd. from benzene, elem. anal.;	95%

: 484065-57-8
[(κ(2)-P,N)-Me2NCH2CH2PPh2]Pt(CD3)2

: 74-87-3
methylene chloride

: 484065-61-4
[(κ(2)-P,N)-Ph2PCH2CH2NMe2]PtMe(CD3)3Cl

Conditions

Conditions	Yield
In benzene-d6 all manipulations under Ar atm.; MeCl bubbled through soln. of Pt compd., then heated to .60°C for 24 h;	99%

: 57458-27-2
teflic acid

: 74-87-3
methylene chloride

: 97-93-8
triethylaluminum

: AlF20O4Te4(1-)*C2H6Cl(1+)

Conditions

Conditions	Yield
at -40℃; Schlenk technique; Glovebox; Inert atmosphere;	99%

...Expand

: 74-87-3
methylene chloride

: 21476-57-3
1,3-bis(dimethylamino)isopropyl methacrylate

: 1,3-bis(trimethylammonium)-2-propyl methacrylate chloride

Conditions

Conditions	Yield
In acetonitrile at 73℃; under 1500.15 Torr; for 24h; Conversion of starting material;	98.6%
In acetonitrile at 71℃; under 1500.15 Torr; for 23h; Conversion of starting material;	96%
In acetonitrile at 80 - 85℃; under 1500.15 Torr; for 23 - 28h; Product distribution / selectivity;	93.1%
In acetonitrile at 72℃; under 1500.15 Torr; for 23h; Product distribution / selectivity;	90.2%
In acetone at 50 - 80℃; under 1500.15 Torr; for 22 - 25h; Product distribution / selectivity;	53.8%

: 74-87-3
methylene chloride

: 930-69-8
sodium thiophenolate

: 100-68-5
methyl-phenyl-thioether

Conditions

Conditions	Yield
at 160℃; under 66756.7 Torr; for 5h; Temperature; Pressure; Concentration; Autoclave; Inert atmosphere;	98.6%

: 17α-cyano-17β-hydroxyandrost-1,4-dien-3-one

: 74-87-3
methylene chloride

: 2477-61-4
17α-Hydroxypregna-1,4-diene-3,20-dione

Conditions

Conditions	Yield
Stage #1: methylene chloride With magnesium In tetrahydrofuran at 30 - 35℃; Stage #2: 17α-cyano-17β-hydroxyandrost-1,4-dien-3-one In tetrahydrofuran at 50 - 55℃;	98.6%
Stage #1: methylene chloride With magnesium In tetrahydrofuran at 35 - 98℃; Stage #2: 17α-cyano-17β-hydroxyandrost-1,4-dien-3-one In tetrahydrofuran at 50 - 55℃;	92.5%

: 74-87-3
methylene chloride

: N-hydroxy-2-[(N-p-chlorophenyl)-3-pyrazolyloxymethyl]phenylcarbamic acid methyl ester

: 175013-18-0
pyraclostrobin

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In acetone at 30 - 50℃; under 2250.23 - 3750.38 Torr; Reagent/catalyst; Solvent;	98.5%
With N-benzyl-N,N,N-triethylammonium chloride; sodium hydrogencarbonate In water; toluene Reagent/catalyst; Solvent; Autoclave; Alkaline conditions;	96.2%
With nano zinc ferrite In dichloromethane at 120℃; under 3000.3 - 4350.44 Torr; for 4h; Autoclave;	82.4%

: 74-87-3
methylene chloride

: 74-93-1
methylthiol

Conditions

Conditions	Yield
With hydrogen sulfide at 260 - 800℃; under 6000.6 Torr; for 0.216667h; Temperature; Pressure; Inert atmosphere; Calcination;	98.4%
With hydrosulfide anion In gas Rate constant; Thermodynamic data; reaction efficiency, ΔH0Rx;
With sodium hydrogensulfide; water unter Druck;

: 74-87-3
methylene chloride

: 82-45-1
1-amino-9,10-anthracenedione

: 82-38-2
1-(methylamino)anthraquinone

Conditions

Conditions	Yield
With ammonium nitrate In aq. phosphate buffer at 50℃; for 5h; Reagent/catalyst; Solvent;	98.2%

: 280-57-9
1,4-diaza-bicyclo[2.2.2]octane

: 74-87-3
methylene chloride

: 1-Methyl-4-aza-1-azoniabicyclo<2.2.2>octane tetrafluoroborate

Conditions

Conditions	Yield
With sodium tetrafluoroborate In acetonitrile at 20℃;	98%
With sodium tetrafluoroborate In acetonitrile Ambient temperature; sealed tube;	97%

: 74-87-3
methylene chloride

: 35433-73-9
(R)-(-)-9-hydroxydecanoic acid

: 85551-52-6
(-)-(R)-9-Hydroxydecansaeure-methylester

Conditions

Conditions	Yield
	98%

: 280-57-9
1,4-diaza-bicyclo[2.2.2]octane

: 74-87-3
methylene chloride

: 2926-27-4
potassium trifluoromethansulfonate

: 140681-58-9
1-methyl-4-aza-1-azoniabicyclo[2.2.2]octane trifluoromethanesulfonate

Conditions

Conditions	Yield
In acetonitrile Ambient temperature; sealed tube;	98%

...Expand

: 74-87-3
methylene chloride

: 80060-09-9
diafenthiuron

: 1-tert-butyl-3-(2,6-diisopropyl-4-phenoxyphenyl)-2-methylisothiourea

Conditions

Conditions	Yield
With potassium hydroxide In butanone at 70℃; for 4h; Autoclave;	98%

Methyl chloride Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 246.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 41 ,1986,p. 161.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 41 ,1986,p. 161.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Methyl chloride Standards and Recommendations

OSHA PEL: TWA 50 ppm; STEL 100 ppm
ACGIH TLV: TWA 50 ppm; STEL 100 ppm; Not Classifiable as a Human Carcinogen
DFG MAK: 50 ppm (100 mg/m³); Suspected Carcinogen
NIOSH REL: (Monohalomethanes) TWA Reduce to lowest level
DOT Classification: 2.1; Label: Flammable Gas

Methyl chloride Analytical Methods

For occupational chemical analysis use NIOSH: Methyl Chloride, 1001.

Methyl chloride Specification

The Methyl chloride, with the CAS registry number 74-87-3 and EINECS registry number 200-817-4, has the systematic of chloromethane. And the molecular formula of this chemical is CH₃Cl. It is the most abundant organohalogen-anthropogenic or natural–in the atmosphere. It is a kind of colourless gas with a minorly sweet odor, and belongs to the following product categories: Refrigerants; Organics; CCosmetics; CFCsAlphabetic; Allergens; Alpha Sort; C; CH; Volatiles/ Semivolatiles; Alkyl; Halogenated Hydrocarbons; Organic Building Blocks. In addition, it should be stored at 2-8°C.

The physical properties of Methyl chloride are as following: (1)ACD/LogP: 1.11; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.113; (4)ACD/LogD (pH 7.4): 1.113; (5)ACD/BCF (pH 5.5): 4.129; (6)ACD/BCF (pH 7.4): 4.129; (7)ACD/KOC (pH 5.5): 96.046; (8)ACD/KOC (pH 7.4): 96.046; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 0 Å²; (13)Index of Refraction: 1.331; (14)Molar Refractivity: 11.531 cm³; (15)Molar Volume: 56.427 cm³; (16)Polarizability: 4.571×10^-24cm³; (17)Surface Tension: 14.643 dyne/cm; (18)Density: 0.895 g/cm³; (19)Enthalpy of Vaporization: 21.902 kJ/mol; (20)Vapour Pressure: 4074.091 mmHg at 25°C.

Preparation of Methyl chloride: Large amounts of Methyl chloride are produced naturally in the oceans by the action of sunlight on biomass and chlorine in sea foam. However, all Methyl chloride that is used in industry is produced synthetically. It can be prepared by reacting methanol with hydrogen chloride:
CH₃OH + HCl → CH₃Cl + H₂O

Uses of Methyl chloride: It was widely used as refrigerant, but due to its toxicity and flammability, its use has been discontinued. It is used as a chemical intermediate in the production of silicone polymers. It is also used as a solvent in the manufacture of butyl rubber and in petroleum refining. What's more, it also used as a methylating and chlorinating agent in organic chemistry.

You should be cautious while dealing with this chemical. It is a kind of extremely flammable chemical, and has danger of serious damage to health by prolonged exposure through inhalation. What's more, it may cause carcinogenic effect. Therefore, you had better take the following instructions: Keep container in a well-ventilated place; Keep away from sources of ignition - No smoking; Take precautionary measures against static discharges.

You can still convert the following datas into molecular structure:
(1)SMILES: CCl
(2)InChI: InChI=1/CH3Cl/c1-2/h1H3
(3)InChIKey: NEHMKBQYUWJMIP-UHFFFAOYAW

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LCLo	inhalation	129mg/m³/4H (129mg/m³)	BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Archiv fuer Hygiene und Bakteriologie. Vol. 116, Pg. 131, 1936.
dog	LCLo	inhalation	14661ppm/6H (14661ppm)	VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	National Institutes of Health, Bulletin. Vol. 191, Pg. 1, 1949.
guinea pig	LCLo	inhalation	20000ppm/2H (20000ppm)		Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967.
human	LCLo	inhalation	20000ppm/2H (20000ppm)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 386, 1969.
mouse	LC50	inhalation	2200ppm/6H (2200ppm)		Toxicology and Applied Pharmacology. Vol. 86, Pg. 93, 1986.
rat	LC50	inhalation	5300mg/m³/4H (5300mg/m³)		"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 82, 1982.
rat	LD50	oral	1800mg/kg (1800mg/kg)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 86, 1986.

Product Name

Methyl chloride

Synthetic route

Methyl chloride Consensus Reports

Methyl chloride Standards and Recommendations

Methyl chloride Analytical Methods

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