• Name

  1-pentyl-N-(naphthalen-1-yl)-1H-indole-3-carboxamide

• EINECS
• CAS No. 1338925-11-3
• Article Data1
• CAS DataBase
• Density 1.12±0.1 g/cm3 (20 oC 760 Torr), Calc.*
• Solubility Insuluble (4.3E-5 g/L) (25 oC), Calc.*
• Melting Point
• Formula C24H24N2O
• Boiling Point
• Molecular Weight 356.467
• Flash Point
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms MN-24;
• PSA 34.03000
• LogP 6.31000

Synthetic route

1338925-20-4

methyl 1-pentyl-1H-indole-3-carboxylate

134-32-7

1-amino-naphthalene

1338925-11-3

N-(naphthalen-1-yl)-1-pentyl-1H-indole-3-carboxamide

Conditions

Conditions	Yield
Stage #1: 1-amino-naphthalene With trimethylaluminum In 1,2-dichloro-ethane; toluene at 20℃; for 0.166667h; Inert atmosphere; Stage #2: methyl 1-pentyl-1H-indole-3-carboxylate In 1,1,1-trichloroethane; toluene for 24h; Inert atmosphere; Reflux;	85%

942-24-5

3-methoxycarbonylindole

1338925-11-3

N-(naphthalen-1-yl)-1-pentyl-1H-indole-3-carboxamide

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / Inert atmosphere 1.2: 16 h / 0 - 20 °C / Inert atmosphere 2.1: trimethylaluminum / 1,2-dichloro-ethane; toluene / 0.17 h / 20 °C / Inert atmosphere 2.2: 24 h / Inert atmosphere; Reflux View Scheme

110-53-2

1-Bromopentane

1338925-11-3

N-(naphthalen-1-yl)-1-pentyl-1H-indole-3-carboxamide

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / Inert atmosphere 1.2: 16 h / 0 - 20 °C / Inert atmosphere 2.1: trimethylaluminum / 1,2-dichloro-ethane; toluene / 0.17 h / 20 °C / Inert atmosphere 2.2: 24 h / Inert atmosphere; Reflux View Scheme

N-1-Naphthalenyl-1-pentyl-1H-indole-3-carboxamide Specification