N-AMINOETHYLPIPERAZINE supplier

Name
N-Aminoethylpiperazine
EINECS 205-411-0
CAS No. 140-31-8
Article Data29
CAS DataBase
Density 0.958 g/cm³
Solubility soluble in water
Melting Point -19 °C
Formula C₆H₁₅N₃
Boiling Point 220 °C at 760 mmHg
Molecular Weight 129.205
Flash Point 93.3 °C
Transport Information UN 2815 8/PG 3
Appearance colorless liquid
Safety 26-36/37/39-45-61
Risk Codes 21/22-34-43-52/53
Molecular Structure
Hazard Symbols C
Synonyms Piperazine,1-(2-aminoethyl)- (6CI,7CI,8CI);1-(2-Aminoethyl)piperazine;1-(b-Aminoethyl)piperazine;1-Piperazineethylamine;2-(1-Piperazinyl)ethanamine;2-(1-Piperazinyl)ethylamine;2-Piperazinylethylamine;4-(2-Aminoethyl)piperazine;AEP;Ancamine AEP;N-(2-Aminoethyl)piperazine;N-(b-Aminoethyl)piperazine;N-AEP;NSC 38968;
PSA 41.29000
LogP -0.18270

Synthetic route

: 113585-93-6, 120574-64-3
2,5,8,10,13,16-Hexaazapentacyclo<8.6.1.12,5.09,18.013,17>octadecan

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol at 125℃; under 41371.8 Torr; for 6h;	94%

: 18907-76-1
2,2’-(ethane-1,2-diylbis(azanediyl))diacetonitrile

A: 140-31-8
aminoethylpiperazine

B: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With hydrogen at 120℃; under 150015 Torr; Concentration; Temperature; Pressure;	A 5.2% B 87.3%
With hydrogen In tetrahydrofuran; toluene at 120℃; under 150015 Torr; for 500h; Autoclave;	A 6.1% B 83.6%
With hydrogen In tetrahydrofuran; water; toluene at 120℃; under 90009 Torr; for 25h; Autoclave;	A 12.1% B 71.9%
With hydrogen; Cr-doped Raney cobalt catalyst In tetrahydrofuran; water at 120℃; under 150015 Torr; for 3h; Product distribution / selectivity;

: 4097-89-6
2,2',2''-triaminotriethylamine

A: 140-31-8
aminoethylpiperazine

B: tris(2-aminoethyl)ammonium perchlorate

Conditions

Conditions	Yield
Stage #1: 2,2',2''-triaminotriethylamine With copper(II) perchlorate hexahydrate; acetonitrile Stage #2: With nitrogen(II) oxide In acetonitrile at 20℃; for 0.166667h;	A 60% B 30%

: [Cu(tris(2-aminoethyl)amine)(acetonitrile)](ClO4)2

A: 140-31-8
aminoethylpiperazine

B: 14057-91-1
tetrakis(acetonitrile)copper(I) perchlorate

C: tris(2-aminoethyl)ammonium perchlorate

Conditions

Conditions	Yield
With NO In acetonitrile NO purged into soln. of Cu complex in degassed CH3CN (O2-free conditions); stirred (10 min, room temp.); NO removed; layered with benzene; cooled;	A 60% B n/a C 30%

...Expand

: 6820-93-5
2-(2-(piperazin-1-yl)ethyl)isoindoline-1,3-dione

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
With sodium hydroxide
With hydrogenchloride

: 817-09-4
tris-(2-chloroethyl)amine hydrochloride

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
With ammonia at 100℃;

: 151-56-4
ethyleneimine

: 110-85-0
piperazine

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
With hydrogenchloride In water at 30 - 60℃; Rate constant; acid-catalyzed ring opening reactions at various temperature, Ea, ΔH are given;
With hydrogenchloride In water at 30 - 60℃; Yield given;

: N-(2-Amino-ethyl)-N'-(2-chloro-ethyl)-ethane-1,2-diamine

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; Rate constant; Thermodynamic data; Ea, ΔH(excit.), ΔS(excit.);

: Bis-(2-amino-ethyl)-(2-chloro-ethyl)-amine

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; Rate constant; Thermodynamic data; Ea, ΔH(excit.), ΔS(excit.);

: C19H25N3O*H(1+)

A: 140-31-8
aminoethylpiperazine

B: 119-61-9
benzophenone

Conditions

Conditions	Yield
With water In acetonitrile at 30℃; Rate constant;

: 107-15-3
ethylenediamine

A: 110-85-0
piperazine

B: 280-57-9
1,4-diaza-bicyclo[2.2.2]octane

C: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
In water at 300℃; for 15h; Product distribution; Mechanism; other polyamines, amino alcohols and amino ethers;	A n/a B 30 % Chromat. C n/a

...Expand

: 107-06-2
1,2-dichloro-ethane

: 111-40-0
1,5-diamino-3-azapentane

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
In water at 75℃; for 3h;

polyethylenepolyamines: polyethylenepolyamines

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
Heating;

: 7664-41-7
ammonia

: 817-09-4
tris-(2-chloroethyl)amine hydrochloride

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
at 100℃; analoge Reaktionen mit Aminen;

: 107-15-3
ethylenediamine

A: 110-85-0
piperazine

B: 103-76-4
1-(2-hydroxyethyl)piperazine

C: 140-31-8
aminoethylpiperazine

D: 111-41-1
2-(2-Aminoethylamino)ethanol

E: 111-40-0
1,5-diamino-3-azapentane

F: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With hydrogen at 150 - 160℃; under 22502.3 Torr;

...Expand

: 141-43-5
ethanolamine

A: 110-85-0
piperazine

B: 103-76-4
1-(2-hydroxyethyl)piperazine

C: 140-31-8
aminoethylpiperazine

D: 111-41-1
2-(2-Aminoethylamino)ethanol

E: 107-15-3
ethylenediamine

F: 111-40-0
1,5-diamino-3-azapentane

G: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With ammonia; hydrogen at 170℃; under 150015 Torr;

...Expand

: 1051939-67-3
diethylenetriaminemonoacetonitrile

A: 140-31-8
aminoethylpiperazine

B: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With hydrogen

: ethylenediaminemonoacetonitrile

: 18907-76-1
2,2’-(ethane-1,2-diylbis(azanediyl))diacetonitrile

A: 110-85-0
piperazine

B: 140-31-8
aminoethylpiperazine

C: 111-40-0
1,5-diamino-3-azapentane

D: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With hydrogen; Cr-doped Raney cobalt In tetrahydrofuran; water; ethylenediamine at 120℃; under 75007.5 Torr; for 3h; Product distribution / selectivity; Autoclave;

...Expand

: 103-76-4
1-(2-hydroxyethyl)piperazine

A: 110-85-0
piperazine

B: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
With ammonia; hydrogen; Ni/Re (6.8wtpercent/1.8wtpercent) on silica/alumina (80/20) at 180℃; under 104192 - 119190 Torr; for 19h; Product distribution / selectivity; Autoclave;

: 4097-89-6
2,2',2''-triaminotriethylamine

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
nickel on silica/alumina (Sud-Chemie C46-7-03) at 150℃; under 11775.6 - 38512.9 Torr; for 5h; Product distribution / selectivity; Autoclave;

: 102-71-6
triethanolamine

A: 110-85-0
piperazine

B: 103-76-4
1-(2-hydroxyethyl)piperazine

C: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
With ammonia; hydrogen; Ni/Re (6.8wtpercent/1.8wtpercent) on silica/alumina (80/20) at 170℃; under 85781.4 - 99537.9 Torr; for 16h; Product distribution / selectivity; Autoclave;

...Expand

: 102-71-6
triethanolamine

A: 110-85-0
piperazine

B: 103-76-4
1-(2-hydroxyethyl)piperazine

C: 140-31-8
aminoethylpiperazine

D: 3197-06-6
N,N-bis(2-hydroxyethyl)ethylidenediamine

Conditions

Conditions	Yield
With ammonia; hydrogen; Ni/Re (6.8wtpercent/1.8wtpercent) on silica/alumina (80/20) at 170℃; under 85781.4 - 99537.9 Torr; for 10h; Product distribution / selectivity; Autoclave;

...Expand

: 107-15-3
ethylenediamine

A: 110-85-0
piperazine

B: 140-31-8
aminoethylpiperazine

C: 111-40-0
1,5-diamino-3-azapentane

D: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With hydrogen; Ni/Re (6.8wtpercent/1.8wtpercent) on silica/alumina (80/20) at 162℃; under 9551.8 - 38512.9 Torr; for 6h; Product distribution / selectivity; Autoclave;

...Expand

: 112-24-3
triethylentetramine

A: 110-85-0
piperazine

B: 140-31-8
aminoethylpiperazine

C: 24028-46-4
1-<2-(2-aminoethyl)aminoethyl>piperazine

Conditions

Conditions	Yield
With hydrogen; nickel on silica/alumina (Sud-Chemie C46-7-03) at 150℃; under 10379.3 - 32462.1 Torr; for 6h; Product distribution / selectivity; Autoclave;

...Expand

: 112-57-2
N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine

: 112-24-3
triethylentetramine

A: 110-85-0
piperazine

B: 140-31-8
aminoethylpiperazine

C: 24028-46-4
1-<2-(2-aminoethyl)aminoethyl>piperazine

Conditions

Conditions	Yield
nickel on silica/alumina (Sud-Chemie C46-7-03) at 155℃; under 15550.9 - 38512.9 Torr; for 6h; Product distribution / selectivity; Autoclave;

...Expand

: 1211473-51-6
ethylenediaminediacetonitrile

: 540-61-4
2-aminoacetonitrile

A: 140-31-8
aminoethylpiperazine

B: 107-15-3
ethylenediamine

C: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With hydrogen; Cr-doped Raney cobalt In tetrahydrofuran at 120℃; under 37503.8 Torr; Autoclave;

...Expand

: 1211473-51-6
ethylenediaminediacetonitrile

: 540-61-4
2-aminoacetonitrile

A: 140-31-8
aminoethylpiperazine

B: 107-15-3
ethylenediamine

C: 111-40-0
1,5-diamino-3-azapentane

D: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With hydrogen; Cr-doped Raney cobalt In tetrahydrofuran at 120℃; under 37503.8 Torr; Autoclave;

...Expand

: 18907-76-1
2,2’-(ethane-1,2-diylbis(azanediyl))diacetonitrile

A: 110-85-0
piperazine

B: 140-31-8
aminoethylpiperazine

C: 111-40-0
1,5-diamino-3-azapentane

D: 112-24-3
triethylentetramine

Conditions

Conditions	Yield
With hydrogen; Cr-doped Raney cobalt catalyst In tetrahydrofuran; water at 120℃; under 75007.5 Torr; for 3h; Product distribution / selectivity;

...Expand

: 111-40-0
1,5-diamino-3-azapentane

: 108-10-1
4-methyl-2-pentanone

: 67-63-0
isopropyl alcohol

: 140-31-8
aminoethylpiperazine

Conditions

Conditions	Yield
In methanol; water

...Expand

: 140-31-8
aminoethylpiperazine

: 100361-18-0
7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid

: 7-(4-(2-aminoethyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 70℃;	100%

: 140-31-8
aminoethylpiperazine

: 107-13-1
acrylonitrile

: 96680-92-1
3-(4-{2-[bis-(2-cyanoethyl)amino]ethyl}piperazin-1-yl)propionitrile

Conditions

Conditions	Yield
Heating;	99%
In methanol at 20℃; Michael condensation;	94%

: 140-31-8
aminoethylpiperazine

: 166186-30-7
3,3'-dibromo-4,4'-dimethoxy-5,6,5',6'-bis(methylenedioxy)biphenyl-2,2'-dicarboxylic anhydride

: 6,6'-Dibromo-7,7'-dimethoxy-5'-(2-piperazin-1-yl-ethylcarbamoyl)-[4,4']bi[benzo[1,3]dioxolyl]-5-carboxylic acid

Conditions

Conditions	Yield
In benzene for 24h; Ambient temperature;	99%

: 140-31-8
aminoethylpiperazine

: 383-63-1
ethyl trifluoroacetate,

: 87980-84-5
1,1,1-trifluoro-N-(2-piperazin-1-ylethyl)acetamide

Conditions

Conditions	Yield
In tetrahydrofuran at 0 - 20℃; for 2h;	99%

: 140-31-8
aminoethylpiperazine

: 914111-61-8
C49H88N4O24

: C81H160N28O16

Conditions

Conditions	Yield
In ethanol at 20 - 75℃; for 60h;	99%

: 140-31-8
aminoethylpiperazine

: 67-56-1
methanol

: 104-19-8
N-methyl-N'-(2-dimethylaminoethyl)piperazine

Conditions

Conditions	Yield
With 5percent silver supported on titanium oxide at 25℃; for 10h; Inert atmosphere; Sealed tube; UV-irradiation;	99%

: 140-31-8
aminoethylpiperazine

: 85-44-9
phthalic anhydride

: 6820-93-5
2-(2-(piperazin-1-yl)ethyl)isoindoline-1,3-dione

Conditions

Conditions	Yield
In neat (no solvent) at 180℃; for 5h;	98%
at 180 - 200℃; for 3h;	93%
In neat (no solvent) at 160℃; for 4h;

: 140-31-8
aminoethylpiperazine

: 2059-76-9
4-iodophenyl isothiocyanate

: 77995-00-7
4-{2-[3-(4-Iodo-phenyl)-thioureido]-ethyl}-piperazine-1-carbothioic acid (4-iodo-phenyl)-amide

Conditions

Conditions	Yield
In ethanol for 4h; Heating;	98%

: 140-31-8
aminoethylpiperazine

: 13280-60-9
5-amino-2-nitrobenzoic acid

: 5-amino-2-nitro-N-(2-piperazin-1-yl-ethyl)benzamide

Conditions

Conditions	Yield
With 1,1'-carbonyldiimidazole In pyridine at 20 - 80℃; for 2.5h;	98%

: 140-31-8
aminoethylpiperazine

: 1333-84-2, 1344-28-1
aluminum oxide

: 86119-84-8, 7664-38-2
phosphoric acid

: 7732-18-5
water

: H3O(1+)*2H(1+)*HN(CH2CH2)2NCH2CH2NH2*Al3P4O16(3-)=(H3O)(C6N3H17)(Al3P4O16)

Conditions

Conditions	Yield
In water High Pressure; Al2O3 was dispersed in aq. H3PO4 and stirred for 2 h at room temp. N-(2-aminoethyl)-piperazine was added dropwise and stirred for 2 h, gel formed was transferred into Teflon-lined stainless steel autoclave and heatedat 220°C for 36 h; react. mixt. was cooled rapidly, ppt. was filtered, washed with water and air-dried at room temp.;	98%

...Expand

: 140-31-8
aminoethylpiperazine

: 100-52-7
benzaldehyde

: 135330-51-7
N-(β-benzylaminoethyl)piperazine

Conditions

Conditions	Yield
With 1.1 wt% Pd/NiO; hydrogen In ethanol at 25℃; under 760.051 Torr; for 10h;	98%

: 140-31-8
aminoethylpiperazine

: 90-02-8
salicylaldehyde

: 93968-73-1
2-(((2-(piperazin-1-yl)ethyl)imino)methyl)phenol

Conditions

Conditions	Yield
In methanol Reflux;	97.39%
In acetone for 0.5h; Ambient temperature;	96%
In methanol for 3h; Reflux;	88%

: 140-31-8
aminoethylpiperazine

: 75-15-0
carbon disulfide

: 129352-08-5
Potassium; 4-(2-dithiocarboxyamino-ethyl)-piperazine-1-carbodithioate

Conditions

Conditions	Yield
With potassium hydroxide at 60℃;	97%

: 140-31-8
aminoethylpiperazine

: 635-93-8
5-chlorosalicyclaldehyde

: C13H18ClN3O

Conditions

Conditions	Yield
In methanol at 20℃; for 0.5h;	97%
In methanol at 20℃; for 72h;	74%

: 140-31-8
aminoethylpiperazine

: 108-10-1
4-methyl-2-pentanone

: 911415-27-5
4-methyl-N-(2-(piperazin-1-yl)ethyl)pentan-2-imine

Conditions

Conditions	Yield
at 130℃; for 5h;	97%
at 140℃; for 8h;
for 4h; Heating / reflux;
With sodium carbonate Reflux; Inert atmosphere; Dean-Stark;
Stage #1: aminoethylpiperazine; 4-methyl-2-pentanone Inert atmosphere; Reflux; Stage #2: With pentaerythritol tetraglycidyl ether In methanol at 50 - 60℃; Dean-Stark;

: 140-31-8
aminoethylpiperazine

: 60457-62-7
methyl 4-[4-(methyloxy)-4-oxobutyl]disulfanylbutanoate

: di(2-amidoethylpiperazine)-4',4-dithiobutyramide

Conditions

Conditions	Yield
In methanol at 25 - 65℃; for 40h;	97%

: 140-31-8
aminoethylpiperazine

: 1761-61-1
5-bromosalicyclaldehyde

: 639452-69-0
2-((2-(piperazin-1-yl)ethylimino)methyl)-4-bromophenol

Conditions

Conditions	Yield
In methanol at 20℃; for 0.5h;	97%
In ethanol at 20℃; for 1.5h; Reflux;	95%
In methanol for 6h; Reflux;	74.3%
In methanol

: 140-31-8
aminoethylpiperazine

: 762-04-9
phosphonic acid diethyl ester

: 67-64-1
acetone

: C13H30N3O3P

Conditions

Conditions	Yield
at 30 - 60℃;	97%

...Expand

: 140-31-8
aminoethylpiperazine

: 527-69-5
2-furancarbonyl chloride

: 80838-44-4
Furan-2-carboxylic acid {2-[4-(furan-2-carbonyl)-piperazin-1-yl]-ethyl}-amide

Conditions

Conditions	Yield
In benzene for 1h; Heating;	96%

: 140-31-8
aminoethylpiperazine

: 107-06-2
1,2-dichloro-ethane

: 113682-68-1
N,N'-bisethylenediamine

Conditions

Conditions	Yield
In methanol for 8h; Heating;	96%
In methanol for 8h; Heating;	95%
Yield given;

: 140-31-8
aminoethylpiperazine

: 49627-27-2
sulindac sulfide

: (Z)-2-(5-fluoro-2-methyl-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-(2-(piperazin-1-yl)ethyl)acetamide

Conditions

Conditions	Yield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In acetonitrile at 20℃; Inert atmosphere;	96%

: 140-31-8
aminoethylpiperazine

: 3-(bis(pyridin-2-ylmethyl)amino)-4-ethoxycyclobut-3-ene-1,2-dione

: 3-(bis(pyridin-2-ylmethyl)amino)-4-((2-(piperazin-1-yl)ethyl)amino)cyclobut-3-ene-1,2-dione

Conditions

Conditions	Yield
In ethanol at 20℃; for 72h; Inert atmosphere;	96%

: 140-31-8
aminoethylpiperazine

: 4808-48-4
2,3-diphenylmaleic anhydride

: 128143-36-2
3,4-diphenyl-1-<2-(1-piperazinyl)ethyl>-1H-pyrrole-2,5-dione

Conditions

Conditions	Yield
In ethanol for 2h; Ambient temperature;	95%

: 140-31-8
aminoethylpiperazine

: 107-13-1
acrylonitrile

: 68310-66-7
3-(2-Piperazin-1-yl-ethylamino)-propionitrile

Conditions

Conditions	Yield
In benzene for 6h; Heating;	95%

: 140-31-8
aminoethylpiperazine

: 79-11-8
chloroacetic acid

: 136369-41-0
N-methoxycarbonyl-N'-(β-dimethoxycarbonylaminoethyl)piperazine

Conditions

Conditions	Yield
In toluene for 4h; Heating;	95%

: 140-31-8
aminoethylpiperazine

: 6590-96-1
2, 4-dichlorophenyl isothiocyanate

: 77995-01-8
4-{2-[3-(2,4-Dichloro-phenyl)-thioureido]-ethyl}-piperazine-1-carbothioic acid (2,4-dichloro-phenyl)-amide

Conditions

Conditions	Yield
In ethanol for 4h; Heating;	95%

: 140-31-8
aminoethylpiperazine

: 85-43-8
1,2,3,6-Tetrahydrophthalic anhydride

: 52599-47-0
2-(2-Piperazin-1-yl-ethyl)-3a,4,7,7a-tetrahydro-isoindole-1,3-dione

Conditions

Conditions	Yield
at 180 - 200℃; for 3h;	95%

: 140-31-8
aminoethylpiperazine

: 7440-36-0
antimony

: 7704-34-9
sulfur

: (1-2-aminoethyl)piperazine+2H)Sb6S10

Conditions

Conditions	Yield
In water High Pressure; Sb, S and org. compd. diluted with water and heated in autoclave at 170°C for 7 d; cooled to room temp., filtered, washed with deionised water and acetone;elem. anal.;	95%

...Expand

: 140-31-8
aminoethylpiperazine

: 635-93-8
5-chlorosalicyclaldehyde

: 1245707-53-2
2-((2-(piperazin-1-yl)ethylimino)methyl)-4-chlorophenol

Conditions

Conditions	Yield
In methanol at 20℃; for 0.5h;	95%
In methanol for 6h; Reflux;	73.2%
In methanol for 0.5h; Reflux;
In ethanol for 0.5h; Reflux; Green chemistry;
In methanol

: 140-31-8
aminoethylpiperazine

: 98-03-3
thiophene-2-carbaldehyde

: 67-52-7
BARBITURIC ACID

: 126-81-8
dimedone

: 1309833-69-9
8,8‐dimethyl‐10‐[2‐(piperazin‐1‐yl)ethyl]‐5‐(thiophen‐2‐yl)‐8,9‐dihydropyrimido[4,5‐b]quinoline‐2,4,6(1H,3H,5H,7H,10H)‐trione

Conditions

Conditions	Yield
With phosphotungstic acid In ethanol for 6h; Reflux;	95%
Stage #1: thiophene-2-carbaldehyde; BARBITURIC ACID; dimedone With polyphosphoric acid supported on CoFe2O4 nanoparticles In ethanol for 0.0166667h; Sonication; Green chemistry; Stage #2: aminoethylpiperazine In ethanol for 0.05h; Sonication; Green chemistry;	95%

...Expand

N-AMINOETHYLPIPERAZINE Chemical Properties

Molecular Structure of N-aminoethylpiperazine (140-31-8):

MF: C₆H₁₅N₃
MW: 129.2
Synonyms: LABOTEST-BB LTBB000498;AMINOETHYLPIPERAZINE;AKOS BBS-00004342;AEP;1-(2-AMINOETHYL)PIPERAZINE;2-(1-PIPERAZINYL)ETHYLAMINE;1-piperazineethanamine;2-PIPERAZINOETHYLAMINE
Product Categories: Piperaizine;Piperazines
Mol File: 140-31-8.mol
mp -19 °C
bp 218-222 °C(lit.)
density 0.985 g/mL at 25 °C(lit.)
vapor density 4.4 (vs air)
vapor pressure 0.05 mm Hg ( 20 °C)
refractive index n20/D 1.500
Fp 200 °F
Water Solubility soluble
Sensitive Air Sensitive
BRN 104363
CAS DataBase Reference 140-31-8(CAS DataBase Reference)
NIST Chemistry Reference 140-31-8(NIST)

N-AMINOETHYLPIPERAZINE Uses

N-aminoethylpiperazine (140-31-8) could be used with Pharmaceutical Intermediates.
Also,Delamine N-Aminoethylpiperazine(140-31-8) is appropriate for use in:
Bitumen Chemicals
Corrosion Inhibitors
Epoxy Curing Agents
Lube Oil and fuel additives
Mineral Processing Aids
Polyamide Resins
Urethane chemicals
Wet Strength Resins

N-AMINOETHYLPIPERAZINE Production

N-aminoethylpiperazine (140-31-8) is a reaction to produce ethylene dichloride and ammonia by-product of ethylenediamine class products.
N-aminoethylpiperazine (140-31-8) of the consumption of raw materials fixed: dichloroethane 2100kg / t, liquid ammonia 620kg / t, caustic soda (42%) 4143kg / t.

N-AMINOETHYLPIPERAZINE Toxicity Data With Reference

1.	skn-rbt 100 µg/24H open	AIHAAP American Industrial Hygiene Association Journal. 23 (1962),95.
2.	skn-rbt 5 mg/24H SEV	85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,864.
3.	eye-rbt 20 mg/24H MOD	85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,864.
4.	sce-ham:ovr 125 µg/L	MUREAV Mutation Research. 320 (1994),31.
5.	msc-ham:ovr 500 µg/L	MUREAV Mutation Research. 320 (1994),31.
6.	otr-mus:lym 1 mL/L	ENMUDM Environmental Mutagenesis. 4 (1982),390.
7.	orl-rat LD50:2140 mg/kg	AIHAAP American Industrial Hygiene Association Journal. 23 (1962),95.
8.	ipr-mus LD50:250 mg/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 .
9.	skn-rbt LD50:880 mg/kg	UCDS** Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 6/13/69 .

N-AMINOETHYLPIPERAZINE Consensus Reports

Reported in EPA TSCA Inventory.

N-AMINOETHYLPIPERAZINE Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion and skin contact. Experimental reproductive effects. A skin and eye irritant. Mutation data reported. See also AMINES. Moderately flammable when exposed to heat, flame, sparks, or powerful oxidizers. To fight fire, use alcohol foam. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes C

Safety Statements 26-36/37/39-45-61
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
61: Avoid release to the environment. Refer to special instructions safety data sheet

N-AMINOETHYLPIPERAZINE Standards and Recommendations

DOT Classification: 8; Label: Corrosive

Product Name

N-Aminoethylpiperazine

Synthetic route

N-AMINOETHYLPIPERAZINE Chemical Properties

N-AMINOETHYLPIPERAZINE Uses

N-AMINOETHYLPIPERAZINE Production

N-AMINOETHYLPIPERAZINE Toxicity Data With Reference

N-AMINOETHYLPIPERAZINE Consensus Reports

N-AMINOETHYLPIPERAZINE Safety Profile

N-AMINOETHYLPIPERAZINE Standards and Recommendations

Related Products

Hot Products