• Name

  N-Methylaminopropyltrimethoxysilane

• EINECS 221-334-5
• CAS No. 3069-25-8
• Article Data7
• CAS DataBase
• Density 0.93 g/cm³
• Solubility Hydrolyzes in water.
• Melting Point
• Formula C₇H₁₉NO₃Si
• Boiling Point 181.9 °C at 760 mmHg
• Molecular Weight 193.318
• Flash Point 63.8 °C
• Transport Information
• Appearance
• Safety 26-36
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms Propylamine,N-methyl-3-(trimethoxysilyl)- (7CI,8CI);(Methylaminopropyl)trimethoxysilane;(N-Methyl-3-aminopropyl)trimethoxysilane;(N-Methylaminopropyl)trimethoxysilane;(Trimethoxysilylpropyl)methylamine;3-(N-Methylaminopropyl)trimethoxysilane;Dynasylan 1110;N-Methyl-3-(trimethoxysilyl)-1-propanamine;N-Methyl-3-(trimethoxysilyl)propylamine;N-Methyl-g-aminopropyltrimethoxysilane;N-[3-(Trimethoxysilyl)propyl)methanamine;Silane 1110;Trimethoxy(3-(methylamino)propyl)silane;X 12-636;XZ 2024;[3-(Methylamino)propyl]trimethoxysilane;Trimethoxy[3-(methylamino)propyl]silane;
• PSA 39.72000
• LogP 0.86490

Synthetic route

74-89-5

methylamine

2530-87-2

3-Chloropropyltrimethoxysilan

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

627-37-2

N-methyl-N-allylamine

2487-90-3

trimethoxysilane

A

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

B

C7H19NO3Si

Conditions

Conditions	Yield
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 80℃; for 20h; Schlenk technique; Inert atmosphere; Overall yield = 93.2 %Spectr.; regioselective reaction;

...Expand

108-55-4

glutaric anhydride,

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

C12H25NO6Si

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃;	100%

30674-80-7

2-Isocyanatoethyl methacrylate

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1560012-77-2

3,3-dimethoxy-7-methyl-8-oxo-2-oxa-7,9-diaza-3-silaundecan-11-yl methacrylate

Conditions

Conditions	Yield
at 60℃;	100%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

376-68-1

hexafluoroglutaric anhydride

C12H19F6NO6Si

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 0.5h;	99%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

106-89-8

epichlorohydrin

N-(2',3'-epoxypropyl)-(3-N-methylaminopropyl)-trimethoxysilane

Conditions

Conditions	Yield
With potassium carbonate In toluene for 16h; Reflux; Inert atmosphere;	96%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

376-68-1

hexafluoroglutaric anhydride

20667-12-3

silver(l) oxide

876734-90-6

(H3CO)3Si(CH2)3N(CH3)C(O)(CF2)3COO(1-)*Ag(1+)=Ag[(H3CO)3Si(CH2)3N(CH3)C(O)(CF2)3COO]

Conditions

Conditions	Yield
In further solvent(s) under Ar, Schlenk setup, glutaric anhydride (1.4 mmol) in MTBE added to soln. of silicon compd. (1.4 mmol), stirred for 10 min, added to Ag2O (1.4 mmol) suspd. in MTBE, stirred for 18 h at room temp. in darkness; evapd. (vac.), elem. anal.;	93%

...Expand

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

75-36-5

acetyl chloride

N-methyl-N-(3-(trimethoxysilyl)propyl)acetamide

Conditions

Conditions	Yield
Stage #1: N-methyl-3-trimethoxysilylpropylamine With trimethylamine In dichloromethane at 0℃; for 0.166667h; Inert atmosphere; Stage #2: acetyl chloride In dichloromethane for 4.5h;	85%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

82113-65-3

bis(trifluoromethanesulfonyl)amide

C32H80N8O12Si8*8C2HF6NO4S2

Conditions

Conditions	Yield
In water; dimethyl sulfoxide at 25 - 100℃; for 19h;	84%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

109-64-8

1,3-dibromo-propane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

Conditions

Conditions	Yield
at 130℃; for 3h; Inert atmosphere; Industrial scale;	80%

2162-98-3

1,10-dichlorodecane

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,10-decanediamine

Conditions

Conditions	Yield
at 130℃; for 5h; Inert atmosphere;	78.8%

16130-58-8

cyanoacetic acid chloride

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N-methyl-N-(3-trimethoxysilyl propyl)cyanoacetamide

Conditions

Conditions	Yield
With pyridine In diethyl ether at 20℃; for 2.5h;	75%
With pyridine In diethyl ether at 20℃; for 2.5h;	75%

628-76-2

1,5-dichloropentane

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,5-pentanediamine

Conditions

Conditions	Yield
at 130℃; for 5h; Inert atmosphere;	74.8%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

142-28-9

1,3-Dichloropropane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

Conditions

Conditions	Yield
at 130℃; for 3h; Inert atmosphere; Industrial scale;	72.8%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

110-56-5

1,4-dichlorobutane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,4-butanediamine

Conditions

Conditions	Yield
at 130℃; for 5h; Inert atmosphere;	72.6%
at 130℃; for 5h; Inert atmosphere;	72.6%

24772-65-4

1,12-diiodododecane

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,12-dodecanediamine

Conditions

Conditions	Yield
at 130℃; for 5h; Inert atmosphere;	67.5%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

109-70-6

1,3-chlorobromopropane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

Conditions

Conditions	Yield
at 130℃; for 3h; Inert atmosphere;	66.4%
at 130℃; for 3h; Inert atmosphere; Industrial scale;	66.4%

307531-92-6

1,3,5,7,9,11,14-heptaisobutyltricyclo[7.3.3.15,11]heptasiloxane-endo-3,7,14-triol

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1228187-76-5

N-(3-([heptaisobutyl]octasilsesquioxane)propyl)methanamine

Conditions

Conditions	Yield
With triethylamine In acetone for 48h; Reflux;	64.7%

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

2163-00-0

1,6-dichlorohexane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,6-hexanediamine

Conditions

Conditions	Yield
at 130℃; for 5h; Concentration; Inert atmosphere;	60.9%

4549-32-0

1,8-dibromooctane

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,8-octanediamine

Conditions

Conditions	Yield
at 130℃; for 5h; Inert atmosphere;	41.7%

821-76-1

1,7-dichloroheptane

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,7-heptanediamine

Conditions

Conditions	Yield
at 130℃; for 5h; Inert atmosphere;	40.5%

420-12-2

thirane

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

18107-13-6

N-Methyl-N-(3-trimethoxy-silylpropyl)-2-amino-ethanthiol

Conditions

Conditions	Yield
In 1,4-dioxane

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

methyl-(3-trifluorosilanyl-propyl)-amine; compound with trifluoroborane

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate

2826-22-4

4-fluorobenzylidenemalononitrile

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

C17H23N3O3Si

Conditions

Conditions	Yield
In various solvent(s)

327-92-4

1,5-difluoro-2,4-dinitrobenzene

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

C13H20FN3O7Si

Conditions

Conditions	Yield
In various solvent(s) at 50℃; for 0.5h;

327-92-4

1,5-difluoro-2,4-dinitrobenzene

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

C20H38N4O10Si2

Conditions

Conditions	Yield
In various solvent(s) at 130℃; for 2h;

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

33386-21-9, 53369-00-9

(1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-one

C24H30FNO4Si

Conditions

Conditions	Yield
In various solvent(s)

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

A

T8-(CH2CH2CH2NHCH3)8

B

T10-(CH2CH2CH2NHCH3)10

C

T12-(CH2CH2CH2NHCH3)12

Conditions

Conditions	Yield
With water In propan-1-ol at 60℃;

...Expand

3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1221231-36-2

1-fluoro-2-nitro-4-[(E)-2-(4-nitrophenyl)vinyl]-benzene

1221231-39-5

C21H27N3O7Si

Conditions

Conditions	Yield
With tetraethoxy orthosilicate for 5h; Inert atmosphere; Reflux;

N-Methylaminopropyltrimethoxysilane Chemical Properties

N-Methylaminopropyltrimethoxysilane Safety Profile