Product Name

  • Name

    BOC-D-DAP-OH

  • EINECS
  • CAS No. 76387-70-7
  • Article Data40
  • CAS DataBase
  • Density 1.189g/cm3
  • Solubility
  • Melting Point 200-203℃
  • Formula C8H16 N2 O4
  • Boiling Point 364.4oC at 760 mmHg
  • Molecular Weight 204.226
  • Flash Point 174.2oC
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 76387-70-7 (BOC-D-DAP-OH)
  • Hazard Symbols
  • Synonyms Boc-D-Dap-OH
  • PSA 101.65000
  • LogP 1.01420

Synthetic route

N-tert-butyloxycarbonylasparagine
7536-55-2

N-tert-butyloxycarbonylasparagine

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene In water; ethyl acetate; acetonitrile at 10℃; Hofmann Rearrangement;90%
With [bis(acetoxy)iodo]benzene In water; ethyl acetate; acetonitrile at 16 - 20℃;88%
With [bis(acetoxy)iodo]benzene In water; ethyl acetate; acetonitrile at 16 - 20℃; for 4.5h;88%
(S)-3-(tert-butoxycarbonylamino)-oxetan-2-one
98541-64-1

(S)-3-(tert-butoxycarbonylamino)-oxetan-2-one

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
With ammonia In tetrahydrofuran at 0℃; for 1h;79%
Boc-Asn

Boc-Asn

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
With pyridine; bis-[(trifluoroacetoxy)iodo]benzene 1.) aq. DMF, 15 min, 25 deg C, 2.) 4 h, 25 deg C; Yield given. Multistep reaction;
S-2-benzyloxycarbonyl-4-<(tert-butoxycarbonyl)amino>-isoxazolidin-5-one
158220-88-3

S-2-benzyloxycarbonyl-4-<(tert-butoxycarbonyl)amino>-isoxazolidin-5-one

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol for 24h; Yield given;
(R)-2-((tert-butoxycarbonyl)amino)-3-chloropropanoic acid
71404-98-3

(R)-2-((tert-butoxycarbonyl)amino)-3-chloropropanoic acid

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 93 percent / 1-ethyl-3-<3-(dimethylamino)propyl>-carbodiimide / CH2Cl2 / 15 h / Ambient temperature
2: 1.) sodium iodide, 2.) 60percent sodium hydride in mineral oil / 1.) dimethylformamide, 0 deg C, 30 min, 2.) dimethylformamide, 0 deg C, 15 min; room temperature, 90 min
3: hydrogen / 10percent Pd/C / methanol / 24 h
View Scheme
1-O-(benzyloxycarbamoyl)-(N-tert-butoxycarbonyl)-β-chloro-L-alanine
158220-90-7

1-O-(benzyloxycarbamoyl)-(N-tert-butoxycarbonyl)-β-chloro-L-alanine

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) sodium iodide, 2.) 60percent sodium hydride in mineral oil / 1.) dimethylformamide, 0 deg C, 30 min, 2.) dimethylformamide, 0 deg C, 15 min; room temperature, 90 min
2: hydrogen / 10percent Pd/C / methanol / 24 h
View Scheme
(S)-3-Benzyloxyamino-2-tert-butoxycarbonylamino-propionic acid
210547-97-0

(S)-3-Benzyloxyamino-2-tert-butoxycarbonylamino-propionic acid

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 760.051 Torr;
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium carbonate / water; 1,4-dioxane / 0 - 20 °C
2: [bis(acetoxy)iodo]benzene / water; ethyl acetate; acetonitrile / 0.42 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / 1,4-dioxane; water / 16 h
2: [bis(acetoxy)iodo]benzene / water; ethyl acetate; acetonitrile
View Scheme
(S)-3-Benzylamino-2-tert-butoxycarbonylamino-propionic acid
124730-06-9

(S)-3-Benzylamino-2-tert-butoxycarbonylamino-propionic acid

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Conditions
ConditionsYield
With cyclohexa-1,4-diene; palladium 10% on activated carbon In ethanol at 25℃;
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

(S)-methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate
61040-20-8

(S)-methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate

Conditions
ConditionsYield
In methanol; diethyl ether; dichloromethane at 20℃; for 2h;99%
In methanol at 20℃; for 2h;99%
In methanol; diethyl ether; dichloromethane at 20℃; for 2h;99%
In methanol; hexane; dichloromethane at 20℃;89%
In methanol
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(S)-2-tert-butoxycarbonylamino-3-(tolyl-4'-sulfonylamino)-propionic acid
72071-27-3

(S)-2-tert-butoxycarbonylamino-3-(tolyl-4'-sulfonylamino)-propionic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate; sodium hydroxide In 1,4-dioxane; water at 0 - 20℃; for 2.5h; pH=9; Inert atmosphere;99%
With sodium carbonate In 1,4-dioxane; water at 20℃;91%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

2,5-dioxopyrrolidin-1-yl (1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethyl) carbonate

2,5-dioxopyrrolidin-1-yl (1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethyl) carbonate

(2S)-2-[(tert-butoxycarbonyl)amino]-3-({[1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy]carbonyl}amino)propanoic acid

(2S)-2-[(tert-butoxycarbonyl)amino]-3-({[1-(6-nitrobenzo[d][1,3]dioxol-5-yl)ethoxy]carbonyl}amino)propanoic acid

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; acetonitrile at 20℃; for 24h; Inert atmosphere; Darkness;99%
1-[(26-oxo-2,5,8,11,14,17,20,23-octaoxahexacosan-26-yl)oxy]pyrrolidine-2,5-dione
756525-90-3

1-[(26-oxo-2,5,8,11,14,17,20,23-octaoxahexacosan-26-yl)oxy]pyrrolidine-2,5-dione

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

(29S)-29-[(tert-butoxycarbonyl)amino]-26-oxo-2,5,8,11,14,17,20,23-octaoxa-27-azatriacontan-30-oic acid

(29S)-29-[(tert-butoxycarbonyl)amino]-26-oxo-2,5,8,11,14,17,20,23-octaoxa-27-azatriacontan-30-oic acid

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h;99%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

ortho-nitrofluorobenzene
1493-27-2

ortho-nitrofluorobenzene

(S)-2-((tert-butoxycarbonyl)amino)-3-((2-nitrophenyl)amino)-propanoic acid
175211-37-7

(S)-2-((tert-butoxycarbonyl)amino)-3-((2-nitrophenyl)amino)-propanoic acid

Conditions
ConditionsYield
With potassium carbonate In ethanol; water for 24h; Heating / reflux;98%
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 70℃; for 18h;83%
With sodium hydrogencarbonate In ethanol; water for 20h; Reflux;69%
2,6-difluoro-1-nitrobenzene
19064-24-5

2,6-difluoro-1-nitrobenzene

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

(S)-2-((tert-butoxycarbonyl)amino)-3-((3-fluoro-2-nitrophenyl)amino)propanoic acid

(S)-2-((tert-butoxycarbonyl)amino)-3-((3-fluoro-2-nitrophenyl)amino)propanoic acid

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 20℃; for 120h;97%
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 20℃; for 120h;97%
chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

3-(ethoxycarbonyl)amino-N-Boc-L-alanine

3-(ethoxycarbonyl)amino-N-Boc-L-alanine

Conditions
ConditionsYield
With sodium hydrogencarbonate In 1,4-dioxane; water at 0 - 20℃; for 16h;96%
hex-5-ynoic acid 2,5-dioxo-pyrrolidin-1-yl ester
906564-59-8

hex-5-ynoic acid 2,5-dioxo-pyrrolidin-1-yl ester

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

C14H22N2O5

C14H22N2O5

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 5h;95%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

benzyl chloroformate
501-53-1

benzyl chloroformate

3-{[(benzyloxy)carbonyl]amino}-N-(tert-butoxycarbonyl)-L-alanine
65710-57-8

3-{[(benzyloxy)carbonyl]amino}-N-(tert-butoxycarbonyl)-L-alanine

Conditions
ConditionsYield
With potassium hydroxide; potassium carbonate In tetrahydrofuran; water94%
With potassium hydroxide; potassium carbonate In tetrahydrofuran; water; toluene at -5℃; for 9h; Inert atmosphere;94%
With potassium hydroxide; potassium carbonate In tetrahydrofuran; water Inert atmosphere;94%
5-(dimethylamino)naphth-1-ylsulfonyl chloride
605-65-2

5-(dimethylamino)naphth-1-ylsulfonyl chloride

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

C20H27N3O6S
654644-65-2

C20H27N3O6S

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 12h; Inert atmosphere;94%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

3-pentynoic acid N-hydroxysuccinimide ester

3-pentynoic acid N-hydroxysuccinimide ester

N2-BOC-N3-(3-pentynoyl)-amino-L-alanine
110480-75-6

N2-BOC-N3-(3-pentynoyl)-amino-L-alanine

Conditions
ConditionsYield
93%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

phenyl chloroformate
1885-14-9

phenyl chloroformate

3-{[(benzyloxy)carbonyl]amino}-N-(tert-butoxycarbonyl)-L-alanine
65710-57-8

3-{[(benzyloxy)carbonyl]amino}-N-(tert-butoxycarbonyl)-L-alanine

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane; water at 25℃; for 3h;93%
5-bromo-3-methyl-4-nitro-1,2-thiazole
35610-98-1

5-bromo-3-methyl-4-nitro-1,2-thiazole

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

(S)-2-((tert-butoxycarbonyl)amino)-3-((3-methyl-4-nitroisothiazol-5-yl)amino)propanoic acid

(S)-2-((tert-butoxycarbonyl)amino)-3-((3-methyl-4-nitroisothiazol-5-yl)amino)propanoic acid

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 25℃; for 16h;91%
C18H15Cl2NO4
935676-49-6

C18H15Cl2NO4

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

C26H29Cl2N3O7
935676-53-2

C26H29Cl2N3O7

Conditions
ConditionsYield
Stage #1: C18H15Cl2NO4 With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 0 - 20℃; for 1.5h;
Stage #2: (S)-3-amino-2-tert-butoxycarbonylaminopropionic acid With triethylamine In N,N-dimethyl-formamide for 24h; Further stages.;		90%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

11-(4-(4-methylbenzoyl)phenyl)undecanoic acid
128596-03-2

11-(4-(4-methylbenzoyl)phenyl)undecanoic acid

(S)-2-(tert-butoxycarbonylamino)-3-(11-(4-(4-methylbenzoyl)phenyl)undecanamido)propanoic acid
1353054-47-3

(S)-2-(tert-butoxycarbonylamino)-3-(11-(4-(4-methylbenzoyl)phenyl)undecanamido)propanoic acid

Conditions
ConditionsYield
Stage #1: 11-(4-(4-methylbenzoyl)phenyl)undecanoic acid With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane for 0.166667h;
Stage #2: (S)-3-amino-2-tert-butoxycarbonylaminopropionic acid In methanol; dichloromethane at 20℃; for 2.5h; Darkness;		90%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

N-succinimidoyl (S)-2-bromosuccinamoate

N-succinimidoyl (S)-2-bromosuccinamoate

N2-(tert-butoxycarbonyl),N3-(S)-2-bromosuccinamoyl,(S)-2,3-diaminopropanoic acid
158381-70-5

N2-(tert-butoxycarbonyl),N3-(S)-2-bromosuccinamoyl,(S)-2,3-diaminopropanoic acid

Conditions
ConditionsYield
With sodium hydroxide In methanol Ambient temperature;89%
formaldehyd
50-00-0

formaldehyd

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

Boc-L-β-dimethylaminoalanine

Boc-L-β-dimethylaminoalanine

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 21 - 23℃; for 48h; Inert atmosphere;89%
2,5-dioxopyrrolidin-1-yl pent-4-ynoate
132178-37-1

2,5-dioxopyrrolidin-1-yl pent-4-ynoate

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

C13H20N2O5

C13H20N2O5

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 5h;89%
N-acetamido cinnamic acid
55065-02-6, 64590-80-3, 5469-45-4

N-acetamido cinnamic acid

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

C19H25N3O6

C19H25N3O6

Conditions
ConditionsYield
Stage #1: N-acetamido cinnamic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 0 - 20℃; for 3h;
Stage #2: (S)-3-amino-2-tert-butoxycarbonylaminopropionic acid With triethylamine In N,N-dimethyl-formamide for 24h; Further stages.;		88%
4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid methyl ester
1455091-10-7

4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid methyl ester

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

2-(S)-tert-butoxycarbonylamino-3-[(4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]propionic acid
1455091-19-6

2-(S)-tert-butoxycarbonylamino-3-[(4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]propionic acid

Conditions
ConditionsYield
With sodium methylate In methanol for 30h; Reflux;88%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

1,3:4,6-Bis(1,4-(6-chloro-1,4-dioxahexyl)-2,3-xylylene)tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione
118715-67-6

1,3:4,6-Bis(1,4-(6-chloro-1,4-dioxahexyl)-2,3-xylylene)tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione

C64H82N8O18

C64H82N8O18

Conditions
ConditionsYield
With sodium carbonate; sodium iodide In acetonitrile for 4h; Heating;87%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

N,N'-bis( tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine
152120-54-2, 862686-58-6, 1143572-00-2

N,N'-bis( tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine

C19H34N4O8
1248587-09-8

C19H34N4O8

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;87%
3-fluoro-4-nitrobenzonitrile
218632-01-0

3-fluoro-4-nitrobenzonitrile

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

(S)-2-tert-butoxycarbonyl amino-3-(5-cyano-2-nitro-phenylamino)-propionic acid

(S)-2-tert-butoxycarbonyl amino-3-(5-cyano-2-nitro-phenylamino)-propionic acid

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 3h; Inert atmosphere;85.4%
2,5‐dioxopyrrolidin‐1‐yl cinnamate
23776-87-6

2,5‐dioxopyrrolidin‐1‐yl cinnamate

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

(S)-2-tert-Butoxycarbonylamino-3-[(E)-(3-phenyl-acryloyl)amino]-propionic acid
159581-09-6

(S)-2-tert-Butoxycarbonylamino-3-[(E)-(3-phenyl-acryloyl)amino]-propionic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In methanol; water for 4h;85%
acetic anhydride
108-24-7

acetic anhydride

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

α-N-tert-butoxycarbonyl-β-acetylamino-L-alanine
158220-97-4

α-N-tert-butoxycarbonyl-β-acetylamino-L-alanine

Conditions
ConditionsYield
With pyridine In dichloromethane for 24h;84%
With pyridine In dichloromethane at 25℃; for 16h; Inert atmosphere;
formaldehyd
50-00-0

formaldehyd

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

N-(tert-butoxycarbonyl)-3-(dimethylamino)-L-alanine
94778-71-9

N-(tert-butoxycarbonyl)-3-(dimethylamino)-L-alanine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol; water84%
Stage #1: formaldehyd; (S)-3-amino-2-tert-butoxycarbonylaminopropionic acid In ethanol; water at 0℃; for 0.166667h;
Stage #2: With sodium cyanoborohydride at 20℃;
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

benzoyl chloride
98-88-4

benzoyl chloride

(S)-N2-(tert-butoxycarbonyl)-N3-benzoyl-2,3-diaminopropionic acid
538314-09-9

(S)-N2-(tert-butoxycarbonyl)-N3-benzoyl-2,3-diaminopropionic acid

Conditions
ConditionsYield
Stage #1: (S)-3-amino-2-tert-butoxycarbonylaminopropionic acid; benzoyl chloride With sodium hydroxide In water at 5 - 25℃; for 2h;
Stage #2: With hydrogenchloride In water pH=2.5;		83.9%
With sodium hydroxide In 1,4-dioxane; water at 20℃; Cooling with ice;
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

(S)-2,3-diaminopropanoic acid hydrochloride
1482-97-9

(S)-2,3-diaminopropanoic acid hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane for 1h; Ambient temperature;83%
(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid
76387-70-7

(S)-3-amino-2-tert-butoxycarbonylaminopropionic acid

6-<4-(4-n-hexylbenzoyl)phenyl>hexanoic acid
147299-36-3

6-<4-(4-n-hexylbenzoyl)phenyl>hexanoic acid

(S)-2-(tert-butoxycarbonylamino)-3-(6-(4-(4-hexylbenzoyl)phenyl)hexanamido)propanoic acid
1353054-42-8

(S)-2-(tert-butoxycarbonylamino)-3-(6-(4-(4-hexylbenzoyl)phenyl)hexanamido)propanoic acid

Conditions
ConditionsYield
Stage #1: 6-<4-(4-n-hexylbenzoyl)phenyl>hexanoic acid With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane for 0.166667h;
Stage #2: (S)-3-amino-2-tert-butoxycarbonylaminopropionic acid In methanol; dichloromethane at 20℃; for 12h; Darkness;		83%

N-alpha-Boc-D-2,3-diaminopropionic acid Chemical Properties

Product Name: N-alpha-Boc-D-2,3-diaminopropionic acid (CAS NO.76387-70-7)

Molecular Formula: C8H16N2O4
Molecular Weight: 204.22g/mol
Mol File: 76387-70-7.mol
Boiling point: 364.4 °C at 760 mmHg
Storage Temperature: Store at RT.
Flash Point: 174.2 °C
Density: 1.189 g/cm3
Surface Tension: 45.7 dyne/cm
Enthalpy of Vaporization: 67.07 kJ/mol
Vapour Pressure: 2.64E-06 mmHg at 25°C

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