Nickel(II) acetate tetrahydrate supplier

Name
Nickel(II) acetate tetrahydrate
EINECS 206-761-7
CAS No. 6018-89-9
Article Data22
CAS DataBase
Density 1.798 g/mL at 25 °C(lit.)
Solubility 182 g/L (20 °C) in water
Melting Point °Cd ec.)
Formula C₄H₁₆NiO₈
Boiling Point 117.1 °C at 760 mmHg
Molecular Weight 248.84
Flash Point 40 °C
Transport Information
Appearance Green monoclinic crystal
Safety 53-36/37-45-24-22
Risk Codes 45-22-43-40
Molecular Structure
Hazard Symbols Xn
Synonyms Diacetatonickeltetrahydrate;Nickel acetate [Ni(OAc)2.4H2O], tetrahydrate;Nickel acetate tetrahydrate;Nickel diacetate tetrahydrate;Nickel(2+) acetate tetrahydrate;Nickel(2+)diacetate tetrahydrate;Nickel(Ⅱ)acetate;
PSA 89.52000
LogP -0.22960

Synthetic route

: 719261-06-0
nickel(II) carbonate

: 7732-18-5
water

: 64-19-7
acetic acid

: 6018-89-9
nickel(II) acetate tetrahydrate

Conditions

Conditions	Yield
In water recrystalization (D2O);

...Expand

: 1313-99-1
nickel(II) oxide

: 64-19-7
acetic acid

: 6018-89-9
nickel(II) acetate tetrahydrate

Conditions

Conditions	Yield
In acetic acid
In acetic acid aq. acetic acid;

: 71-50-1
acetate

: 7440-02-0
nickel

: 6018-89-9
nickel(II) acetate tetrahydrate

Conditions

Conditions	Yield
In water Electrolysis;
In water Electrolysis;

: 64-19-7
acetic acid

: nickel(II) hydroxide

: 6018-89-9
nickel(II) acetate tetrahydrate

Conditions

Conditions	Yield
In acetic acid aq. acetic acid;

: 7440-02-0
nickel

: 64-19-7
acetic acid

: 6018-89-9
nickel(II) acetate tetrahydrate

Conditions

Conditions	Yield
With oxygen In acetic acid heating while passing O2 over a suspension of Ni and NiBr2 in 40% acetic acid at 100°C for more than 3.5 h;;
In acetic acid dissolving in concd. acetic acid, heating;;
With O2; Ni bromide In acetic acid aq. acetic acid; heating while passing O2 over a suspension of Ni and NiBr2 in 40% acetic acid at 100°C for more than 3.5 h;;
In acetic acid aq. acetic acid; dissolving in concd. acetic acid, heating;;
In acetic acid dissolving in concd. acetic acid, heating;;

: nickel(III) oxide hydrate

: 7440-02-0
nickel

: 64-19-7
acetic acid

: 6018-89-9
nickel(II) acetate tetrahydrate

Conditions

Conditions	Yield
In acetic acid in autoclave at 120°C;;
In acetic acid aq. acetic acid; in autoclave at 120°C;;
In acetic acid in autoclave at 120°C;;

...Expand

: nickel(III) oxide

: 7440-02-0
nickel

: 64-19-7
acetic acid

: 6018-89-9
nickel(II) acetate tetrahydrate

Conditions

Conditions	Yield
In acetic acid in autoclave at 120°C;;
In acetic acid aq. acetic acid; in autoclave at 120°C;;
In acetic acid in autoclave at 120°C;;

...Expand

: nickel(II) sulphate

: 543-80-6
barium(II) acetate

: 6018-89-9
nickel(II) acetate tetrahydrate

Conditions

Conditions	Yield
In water
In water

: Ni(2+)*2CH3CO2(1-)*2B2O(CH3CO2)4=Ni(CH3CO2)2*2B2O(CH3CO2)4

A: 11113-50-1
boric acid

B: 6018-89-9
nickel(II) acetate tetrahydrate

C: 64-19-7
acetic acid

Conditions

Conditions	Yield
With water In water
With H2O In water

...Expand

: 917-23-7
5,10,15,20-tetraphenyl-21H,23H-porphine

: 6018-89-9
nickel(II) acetate tetrahydrate

: 14172-92-0
5,10,15,20-tetraphenylporphinatonickel(II)

Conditions

Conditions	Yield
In pyridine other Radiation; porphyrin, metal salt and pyridine were sealed in a glass tube, microwave power of 300 W, heated from room temp. to 180°C, stirred for 15min, cooled to 50°C; vessel was opened, decanted, TLC (silica gel), UV;	100%
In methanol; chloroform tetraphenylporphyrin (300 mg) and Ni(OAc)2*4H2O (1 g) refluxed (16 h) inCHCl3/MeOH (2:1); cooled; solvent removed (vac.); dissolved in CHCl3; chromd. (silica, CHCl3);	99%

: 102942-30-3
Mo(CO)5((C6H5)2PNHCH2CH2NCHC6H4OH)

: 6018-89-9
nickel(II) acetate tetrahydrate

: trans-{Mo(CO)5(Ph2PNHCH2CH2N=CHC6H4-o-O)}2Ni

Conditions

Conditions	Yield
In tetrahydrofuran A mixt. of Ni(OAc)2*4H2O and Mo(CO)5(Ph2PNHCH2CH2NCHC6H4OH) in THF was stirred under Ar at ambient temp. for 42 h.; The mixt. was filtered and then the filtrate evapd. to dryness to yield {Mo(CO)5(Ph2PNHCH2CH2NCHC6H4O)}2Ni.;	100%

: ammonium hexafluorophosphate

: 6018-89-9
nickel(II) acetate tetrahydrate

: 78570-49-7
2,6-bis<2'-(4'-methylthio)-6'-(2''-pyridinyl)pyridinyl>pyridine

: {Ni2((C5H4N)2(C5H2(CH3S)N)2C5H3N)2CH3COO}(3+)*3PF6(1-)*H2O={Ni2((C5H4N)2(C5H2(CH3S)N)2C5H3N)2CH3COO}{PF6}3*H2O

Conditions

Conditions	Yield
In methanol addn of 4.17E-4 mol quinquepyridine to a soln. of 4.17E-4 mol Ni(OOCCH3)2*4H2O in methanol; stirring for 3 h at room temperature; treating with a satd. methanolic soln. of NH4PF6; filtration;; washing with methanol; recrystallization from nitromethane/diethyl ether; elem. anal.;;	100%

...Expand

: (Z)-5,5'-vinylenebis(2,3,7,8,12,13,17,18-octaethylporphyrin)-platinum(II)

: 6018-89-9
nickel(II) acetate tetrahydrate

: (Z)-5,5'-vinylenebis(2,3,7,8,12,13,17,18-octaethylporphyrin)-nickel(II)-platinum(II)

Conditions

Conditions	Yield
In methanol; chloroform mixt. of Pt complex and Ni salt in CHCl3/MeOH (5:3) refluxed for 15 h; poured into H2O, extd. with CHCl3, washed with brine, dried and evapd.,column chromy. on SiO2; recrystn. from CHCl3-MeOH; elem. anal.;	100%

: meso-tetraphenyl-2-oxa-3-oxoporphyrin

: 6018-89-9
nickel(II) acetate tetrahydrate

: 922142-13-0
meso-tetraphenyl-2-oxa-3-oxoporphyrinatonickel(II)

Conditions

Conditions	Yield
In pyridine other Radiation; 3 equiv of Ni-salt, porphyrin, pyridine were sealed in glass tube, stirred under microwave power of 300 W, hetaed from room temp. to 180°C for 15 min; cooled to 50°C, removed from the microwave cavity, opened, decanted, preparative chromy. (petroleum ether-CH2Cl2);	100%

: 5-(4'-iodophenyl)-10,15,20-tris(3'',5''-di-tert-butylphenyl)porphin

: 6018-89-9
nickel(II) acetate tetrahydrate

: 281211-15-2
[5(4'-iodophenyl)tetrakis-10,15,20-tris(3'',5''-di-tert-butylphenyl)porphyrinato]nickel(II)

Conditions

Conditions	Yield
In N,N-dimethyl-formamide refluxed for 40 min; cooled, ether added, washed (water), dried (Na2SO4), filtered,solvent removed, chromy. (silica, dichloromethane/light petroleum), solvent removed, recrystd. (CH2Cl2/CH3OH); elem. anal.;	100%

: 6018-89-9
nickel(II) acetate tetrahydrate

: 362590-31-6
1,4-bis[3-(4-chlorophenyl)-4,6-dimethoxyindol-7-ylmethyleneamino]benzene

: 362590-60-1
(1,4-bis[3-(4-chlorophenyl)-4,6-dimethoxyindol-7-ylmethyleneamino]benzenato(2-))nickel(II)

Conditions

Conditions	Yield
With Et3N In acetonitrile ligand was dissolved at reflux, anhyd. Et3N and the metal salt were added, mixt. was heated at reflux for 8 h; mixt. was filtered warm, ppt. was washed with MeCN followed by anhyd. Et2O, dried in air;	100%

: 6018-89-9
nickel(II) acetate tetrahydrate

: 2-Amino-3-nitro-5,10,15,20-tetraphenylporphyrin

: nickel(II) 2-amino-3-nitro-5,10,15,20-tetraphenylporphyrin

Conditions

Conditions	Yield
With acetic acid In chloroform	100%

: disodium 3-(2-methoxyethoxy)salicylaldehyde-5-sulfonate

: 6018-89-9
nickel(II) acetate tetrahydrate

: 95-54-5
1,2-diamino-benzene

: C26H24N2NiO12S2(2-)*2Na(1+)

Conditions

Conditions	Yield
In methanol for 13h; Reflux;	100%

...Expand

: C25H20O5

: 6018-89-9
nickel(II) acetate tetrahydrate

: C150H102Ni9O30*2H2O

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 20 - 110℃; for 72h; pH=7; Autoclave; High pressure;	100%

: C88H110N4O12

: 6018-89-9
nickel(II) acetate tetrahydrate

: C88H108N4NiO12

Conditions

Conditions	Yield
In methanol; chloroform at 60℃; for 264h; Inert atmosphere;	100%

: C74H68N4

: 6018-89-9
nickel(II) acetate tetrahydrate

: C74H66N4Ni

Conditions

Conditions	Yield
In toluene at 120℃; for 5h; Inert atmosphere;	100%

: methyl-2-(N-[2-(2'-hydroxyphenyl)methylidynenitrilo]ethyl)amino-1-cyclopentenedithiocarboxylate

: 6018-89-9
nickel(II) acetate tetrahydrate

: nickel(II) methyl-2-(N-(2-(2'-phenolate)methylidynenitrilo)ethyl)aminato(1-)-1-cyclopentenedithiocarboxylate

Conditions

Conditions	Yield
In methanol; chloroform addn. of Ni-salt soln. (in MeOH) to equimolar amt. of ligand soln. (in CHCl3/MeOH=2:1), stirring for 15 min; pptn. on standing (room temp., 24 h), recrystn. (MeCN/MeOH=1:1); elem. anal.;	99.8%
In methanol; chloroform stoichiometric amts., ratio CH3OH:CHCl3 1:1, pptn. in several h; recrystn. (CH3CN); elem. anal.;

: 308086-87-5
N-(2-hydroxyl-3,5-di-tert-butylbenzaldehyde)-1-amino-2-benzeneimine

: 6018-89-9
nickel(II) acetate tetrahydrate

: 620595-36-0
2-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

: N-(3,5-di-tert-butylsalicylidene)-N′-(5-(4,4,5,5,-tetramethyl-1,3,2-dioxa-borolan-2-yl)salicylidene)phenylenediaminatonickel(II)

Conditions

Conditions	Yield
Stage #1: N-(2-hydroxyl-3,5-di-tert-butylbenzaldehyde)-1-amino-2-benzeneimine; nickel(II) acetate tetrahydrate With triethylamine In methanol for 0.0833333h; Stage #2: 2-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde In tetrahydrofuran	99.8%

...Expand

: 2-bromo-5,10,15,20-tetraphenylporphyrin

: 6018-89-9
nickel(II) acetate tetrahydrate

: 52588-61-1
(2-bromo-5,10,15,20-tetraphenylporphyrinato)nickel(II)

Conditions

Conditions	Yield
In methanol; chloroform β-tetraphenylporphyrin (240 mg) and Ni(OAc)2*4H2O (800 mg) refluxed(16 h) in CHCl3/MeOH (2:1); cooled; solvent removed (vac.); dissolved in CHCl3; chromd. (silica, CHCl3);	99%

: 102-52-3
malonaldehydebis(dimethylacetal)

: 6018-89-9
nickel(II) acetate tetrahydrate

: 3171-45-7
4,5-dimethyl-1,2-phenylenediamine

: 57574-24-0
{7,16-dihydro-2,3,11,12-tetramethyldibenzo{b,i}{1,4,8,11}tetraazacyclotetradecinato-N5,N9,N14,N18}nickel(II)

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide reflux for 10 h; filtn., chromy.; elem. anal.;;	99%

...Expand

: 2N((CH2)3CH3)4(1+)*Mo2O5(O2C6H2(NCHC6H3(OC2H5)OH)2)2(2-)=[N((CH2)3CH3)4]2[Mo2O5(O2C6H2(NCHC6H3(OC2H5)OH)2)2]

: 6018-89-9
nickel(II) acetate tetrahydrate

: 2N((CH2)3CH3)4(1+)*Mo2O5(O2C6H2(NCHC6H3(OC2H5)O)2Ni)2(2-)=[N((CH2)3CH3)4]2[Mo2O5(O2C6H2(NCHC6H3(OC2H5)O)2Ni)2]

Conditions

Conditions	Yield
In methanol; acetone byproducts: H2O; inert atmosphere; dropwise addn. of metal acetate (in MeOH) to 0.5 equiv. Mn-complex (in Me2CO), stirring for 1 h; solvent removal (vac.), dissoln. in THF/CH2Cl2=10:1, pptn. on Et2O addn., standing overnight;	99%

: 2N((CH2)3CH3)4(1+)*Mo2O5(O2C6H2(NCHC6H2(C(CH3)3)2OH)2)2(2-)=[N((CH2)3CH3)4]2[Mo2O5(O2C6H2(NCHC6H2(C(CH3)3)2OH)2)2]

: 6018-89-9
nickel(II) acetate tetrahydrate

: 2N((CH2)3CH3)4(1+)*Mo2O5(O2C6H2(NCHC6H2(C4H9)2O)2Ni)2(2-)=[N((CH2)3CH3)4]2[Mo2O5(O2C6H2(NCHC6H2(C4H9)2O)2Ni)2]

Conditions

Conditions	Yield
In methanol; acetone byproducts: H2O; inert atmosphere; dropwise addn. of metal acetate (in MeOH) to 0.5 equiv. Mn-complex (in Me2CO), stirring for 1 h; solvent removal (vac.), dissoln. in PhMe, pptn. on addn. of hexanes, standing overnight;	99%

: 4-(trans-2-(5,10,15,20-tetraphenylporphyrin-2-yl)ethen-1-yl)nitrobenzene

: 6018-89-9
nickel(II) acetate tetrahydrate

: Ni(4-(trans-2-(5,10,15,20-tetraphenylporphinato-2-yl)ethen-1-yl)nitrobenzene)

Conditions

Conditions	Yield
In methanol; chloroform; water addn. of excess Ni-salt (in MeOH/water=5:1 v/v) to refluxing soln. of porphyrin in CHCl3, refluxing for 16 h; washing (water), drying (MgSO4), solvent removal (reduced pressure), recrystn. (CH2Cl2/MeOH);	99%

: 1,1'-di(2-picolyl)-3,3'-methylenediimidazolium dibromide

: 6018-89-9
nickel(II) acetate tetrahydrate

: (1,1'-di(2-picolyl)-3,3'-methylenediimidazolin-2,2'-diylidene)nickel(II) dibromide

Conditions

Conditions	Yield
In dimethyl sulfoxide (Schlenk, dry N2) a soln. of bromide and Ni-compound in DMSO was heated at 50°C for 3 h, then at 110°C for 2 h; the solvent was removed under vac., the residue was washed with THF, filtered, dried under vac.; elem. anal.;	99%

: 5,10,15,20-tetrakis(3,5-di-tert-butylphenyl)bisquinoxalino[2,3-b':7,8-b'']porphyrin

: 6018-89-9
nickel(II) acetate tetrahydrate

: 1009836-28-5
[5,10,15,20-tetrakis(3,5-di-tert-butylphenyl)bisquinoxalino[2,3-b':7,8-b'']porphyrinato]nickel(II)

Conditions

Conditions	Yield
In acetic acid; toluene porphyrin and metal salt (1:4) dissolved in toluene and glacial acetic acid, refluxed for 1 min; treated with CH2Cl2, org. phase separated, washed (H2O, Na2CO3 soln., H2O), dried (Na2SO4), filtered, evapd., chromy.(silica gel - light petroleun 1:3), collected, evapd., elem. anal.;	99%

: 47644-69-9, 69678-00-8, 18531-91-4
dimethyl 2,2'-dihydroxy-1,1'-binaphthalene-3,3'-dicarboxylate

: 6018-89-9
nickel(II) acetate tetrahydrate

: [Ni2(H2O)4(2,2'-dihydroxy-3,3'-di(carboxymethyl)-1,1'-binaphthyl(-2H))2]*2H2O

Conditions

Conditions	Yield
With sodium acetate In methanol; pentan-1-ol heating of MeOH soln. of Ni(CH3COO)2*4H2O on water bath; addn. of 2,2'-dihydroxy-2,2'-di(carboxymethyl)-1,1'-binaphthyl in pentanol; adjusting pH to 5.0 by addn. of NaCH3COO; reflux on water bath for 3 h; pptn. upon heating, filtration, washing with EtOH; drying in desiccator over silica gel; elem. anal.;	99%

: 5,10,15,20-tetrakis(4-methylphenyl)porphyrin

: 1020152-19-5
(C5H3N(NCHC6H2(O)(tBu)2)2)Zn

: 6018-89-9
nickel(II) acetate tetrahydrate

: 1143464-63-4
[(tetra(p-tolyl)porphyrinato)Zn(NC5H3(NCHC6H2(C(CH3)3)2O)2)Ni]

Conditions

Conditions	Yield
In tetrahydrofuran stirred at room temp. for 18 h; concd. (vac.), triturated with n-hexane;	99%

...Expand

: 1289376-52-8
[Zn2((C6H3(NCHC6H2(O)(OCH3)CH2CHCH2)NCHC6H2(C(CH3)3)2O)2)]

: 6018-89-9
nickel(II) acetate tetrahydrate

: 1289376-53-9
[Ni2((C6H3(NCHC6H2(O)(OCH3)CH2CHCH2)NCHC6H2(C(CH3)3)2O)2)]

Conditions

Conditions	Yield
In methanol; dichloromethane a MeOH soln. of Ni salt added to a suspn. of Zn complex in CH2Cl2; concd., the residue suspended in MeOH, filtered off, washed (MeOH), dried in air;	99%

: 854139-47-2
15,15-difluoro-1,4,7,10,13-pentaazacyclohexadecane-14,16-dione

: 6018-89-9
nickel(II) acetate tetrahydrate

: 1356598-32-7
[Ni(OAc)2(15,15-difluoro-1,4,7,10,13-pentaazacyclohexadecane-14,16-dione)]

Conditions

Conditions	Yield
In ethanol N2; ligand and Co compd. (1:1 molar ratio) refluxed for 3 h; filtered, evapd., elem. anal.;	99%

: 1443453-72-2
C102H150N8O6S6

: 6018-89-9
nickel(II) acetate tetrahydrate

: C104H152N8NiO6S4

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 155℃; for 3h; Inert atmosphere;	99%

: 5,15-dibromo-10,20-dipentylporphyrin

: 6018-89-9
nickel(II) acetate tetrahydrate

: Ni [5,15-dipentyl-10,20-dibromoporphyrin]

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 140℃; for 5h;	99%

Nickel(II) acetate tetrahydrate Consensus Reports

NTP 10th Report on Carcinogens. Nickel and its compounds are on the Community Right-To-Know List.

Nickel(II) acetate tetrahydrate Standards and Recommendations

OSHA PEL: TWA 0.1 mg (Ni)/m³
ACGIH TLV: TWA 0.2 mg(Ni)/m³; Human Carcinogen
NIOSH REL: (Inorganic Nickel) TWA 0.015 mg(Ni)/m³

Nickel(II) acetate tetrahydrate Specification

The Nickel acetate tetrahydrate, with the CAS registry number 6018-89-9 and EINECS registry number 206-761-7, has the systematic name of nickel(2+) acetate hydrate (1:2:4). It is a kind of hygroscopic green monoclinic crystal. And the molecular formula of this chemical is C₄H₁₆NiO₈. What's more, it is usually used as chemical reagent, and it is also used as catalyst in the nickelage and coloration of metal and nickelage.

The physical properties of Nickel acetate tetrahydrate are as followings: (1)ACD/LogP: -0.29; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.07; (4)ACD/LogD (pH 7.4): -2.86; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 2.73; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 37.3 Å²; (13)Flash Point: 40 °C; (14)Enthalpy of Vaporization: 23.7 kJ/mol; (15)Boiling Point: 117.1 °C at 760 mmHg; (16)Vapour Pressure: 13.9 mmHg at 25°C.

Preparation: Dissolve the basic nickel carbonate in excessive dilute acetic acid. Then, after a series of filtration, evaporation, cooling crystallization and drying, you can get product.

You should be cautious while dealing with this chemical. It is harmful if swallowed, and may cause sensitization by skin contact. What's more, it may cause cancer. Therefore, you had better take the following instructions: Do not breathe dust; Avoid contact with skin ; Avoid exposure - obtain special instruction before use; Wear suitable protective clothing and gloves, and in case of accident or if you feel unwell, seek medical advice immediately (show label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: [Ni+2].[O-]C(=O)C.[O-]C(=O)C.O.O.O.O
(2)InChI: InChI=1/2C2H4O2.Ni.4H2O/c2*1-2(3)4;;;;;/h2*1H3,(H,3,4);;4*1H2/q;;+2;;;;/p-2
(3)InChIKey: OINIXPNQKAZCRL-NUQVWONBAQ

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	45700ug/kg (45.7mg/kg)	Research Communications in Chemical Pathology and Pharmacology. Vol. 30, Pg. 133, 1980.
mouse	LD50	oral	410mg/kg (410mg/kg)	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 455, 1980.
rat	LD50	oral	350mg/kg (350mg/kg)	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 455, 1980.

Product Name

Nickel(II) acetate tetrahydrate

Synthetic route

Nickel(II) acetate tetrahydrate Consensus Reports

Nickel(II) acetate tetrahydrate Standards and Recommendations

Nickel(II) acetate tetrahydrate Specification

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