Penfluridol

Molecular Formula: C₂₈H₂₇ClF₅NO
Molecular Weight; 523.97
EINECS: 248-074-5
Density: 1.29 g/cm3
Storage temp: 2-8°C
Flash Point: 309.2 °C
Solubility: H2O: insoluble
Appearance: white powder
Melting point  105-107 ºC
Index of Refraction: 1.552 
Enthalpy of Vaporization: 92.29 kJ/mol 
Boiling Point: 587.7 °C at 760 mmHg 
Vapour Pressure: 1.17E-14 mmHg at 25°C
Product Categories: API intermediates
IUPAC Name: 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-
4-ol
Synonyms  1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol
Following is the molecular structure of Penfluridol (26864-56-2):

Penfluridol (26864-56-2)is a oral long-acting antipsychotics.It is applicable to all types of mental illness.

Poison by ingestion and intravenous routes. Experimental teratogenic and reproductive effects. A neuroleptic agent. When heated to decomposition it emits very toxic fumes of Cl⁻, F⁻, and NO_x.
Safety Information of Penfluridol (26864-56-2):
Hazard Codes: T
T: Toxic
Risk Statements: 25
25: Toxic if swallowed 
Safety Statements: 45
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)  
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TN6957000

Penfluridol (26864-56-2) is a highly potent, first generation diphenylbutylpiperidine antipsychotic Related to other diphenylbutylpiperidine antipsychotics, pimozide and fluspirilene, penfluridol has an extremely long elimination half-life and its effects last for many days after single oral dose. Its antipsychotic potency, in terms of dose needed to produce comparable effects, is similar to both haloperidol and pimozide. It is only slightly sedative, but often causes extrapyramidal side-effects, such as akathisia, dyskinesiae and pseudo-Parkinsonism. Penfluridol is indicated for antipsychotic treatment of chronic schizophrenia and similar psychotic disorders, it is, however, like most typical antipsychotics, being increasingly replaced by the atypical antipsychotics. Due to its extremely long lasting effects, it is often prescribed to be taken orally as tablets only once a week (q 7 days). The once-weekly dosis is usually 10 — 60 mg.