• Name

  Phosphoric acid-d3

• EINECS 238-285-0
• CAS No. 14335-33-2
• Article Data17
• CAS DataBase
• Density 2.235 g/cm³
• Solubility
• Melting Point 41-44 °C(lit.)
• Formula H₃O₄P
• Boiling Point 157.999 °C at 760 mmHg
• Molecular Weight 100.971
• Flash Point
• Transport Information UN 1805 8
• Appearance clear colorless solution
• Safety 26-36/37/39-45
• Risk Codes 34
• Molecular Structure
• Hazard Symbols C
• Synonyms Deuteriumphosphate (D3PO4);Phosphoric acid-d3(6CI,7CI,8CI,9CI);
• PSA 87.57000
• LogP -0.92860

Synthetic route

57583-55-8

deuterophosphorous acid

tripropylammonium fluorochromate (VI)

A

C5H5NH(1+)*CrO2F(1-)=C5H5NHCrO2F

B

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
In dimethyl sulfoxide Kinetics; React. between 298 and 318 K.; Monitored spectrophotometrically at 356 nm.;

...Expand

barium phosphate

13813-19-9

sulfuric acid-d2

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
formation from diluted (2)H2SO4 and Ba3(PO4)2;;

75-91-2

tert.-butylhydroperoxide

12185-10-3

phosphorous

7789-20-0

water-d2

A

57583-56-9

trideutero hypophosphorous acid

B

57583-55-8

deuterophosphorous acid

C

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
In water-d2; toluene Kinetics; Ar, P4 (or soln. of P4 in toluene) added in small portions, heated to 25-60°C, stirred for 0.5-4 h; not isolated, detected by NMR;
In tetrahydrofuran; water-d2 Kinetics; Ar, P4 added in small portions, heated to 60°C, stirred for 0.5-4h; not isolated, detected by NMR;
In tetrachloromethane; water-d2 Kinetics; Ar, P4 added in small portions, heated to 60°C, stirred for 0.5-4h; not isolated, detected by NMR;
In hexane; water-d2 Kinetics; Ar, P4 added in small portions, heated to 60°C, stirred for 0.5-4h; not isolated, detected by NMR;
In water-d2 Kinetics; Ar, P4 added in small portions, heated to 90°C, stirred for 0.5-4h; not isolated, detected by NMR;

...Expand

12185-10-3

phosphorous

7722-84-1

dihydrogen peroxide

7789-20-0

water-d2

A

57583-56-9

trideutero hypophosphorous acid

B

57583-55-8

deuterophosphorous acid

C

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
In water-d2 Kinetics; Ar, P4 added in small portions, heated to 25-90°C, stirred for 0.5-4 h; not isolated, detected by NMR;

...Expand

12185-10-3

phosphorous

7789-20-0

water-d2

94-36-0

dibenzoyl peroxide

A

57583-56-9

trideutero hypophosphorous acid

B

57583-55-8

deuterophosphorous acid

C

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
In water-d2; toluene Kinetics; Ar, P4 (or soln. of P4 in toluene) added in small portions, heated to 60-60°C, stirred for 0.5-4 h; not isolated, detected by NMR;
copper diacetate In water-d2; toluene Kinetics; Ar, P4 added in small portions, heated to 60°C, stirred for 0.5-4h; not isolated, detected by NMR;
copper(l) iodide In water-d2; toluene Kinetics; Ar, P4 added in small portions, heated to 60°C, stirred for 0.5-4h; not isolated, detected by NMR;

...Expand

7789-20-0

water-d2

phosphorus pentoxide

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
stoich. amts.;
In neat (no solvent)
In water-d2 P-compd. dissoln.;

7789-20-0

water-d2

10025-87-3, 12599-09-6, 63736-95-8

trichlorophosphate

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
In neat (no solvent) formation of diluted soln. with POCl3 and excess (2)H2O;;

P4O10

7789-20-0

water-d2

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
In water-d2

16752-60-6

phosphorus pentoxide

7789-20-0

water-d2

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
In water sublimated P4O10 converted with ultrapure D2O in moisturizing apparatus; filtered through G5 sintered glass frit under CO2-free atmosphere;

57583-55-8

deuterophosphorous acid

tetraethylammonium chlorochromate(VI)

A

tetraethylammonium chlorochromate(IV)

B

14335-33-2

[D3]phosphoric acid

Conditions

Conditions	Yield
In dimethyl sulfoxide Kinetics; react. of (2)HP(O)(O(2)H)2 with O2CrOCl at 298 K; detd. spectrophotometrically;

...Expand

788133-24-4

vanadium(V) oxide

7789-20-0

water-d2

14335-33-2

[D3]phosphoric acid

vanadium(IV) hydrogen phosphate hemihydrate

Conditions

Conditions	Yield
In ethyl [2]alcohol Reflux with stirring for 11 days;; filtered, solid was washed with D2O, dried in vac. at 60°C for 16 h; elem. anal.;;	98.8%

...Expand

sodium cyclopentadienylchromium tricarbonyl

14335-33-2

[D3]phosphoric acid

DCr(CO)3Cp

Conditions

Conditions	Yield
In tetrahydrofuran; water-d2 D3PO4 in D2O added to a soln. of Cr complex in THF, stirred for 45 min; evapd. (vac.), sublimed;	54%

16940-66-2

sodium tetrahydroborate

135584-76-8

Ru3(CO)9(N2(CH3)2)

14335-33-2

[D3]phosphoric acid

(2)HRu3(CO)9(CH3NN(2)HCH3)

Conditions

Conditions	Yield
With {18}crown-6 In tetrahydrofuran Ru-compd., NaBH4 and (18)crown-6 in THF stirred for 2.5 h at room temp., addn. of D3PO4, stirred for 5 min; excess D3PO4 neutralized with NaHCO3, dried with MgSO4, filtered, removal of solvent in vac., dissolved in CH2Cl2, TLC (hexane/CH2Cl2 7:3);	30%

...Expand

14878-26-3

potassium tetracarbonylcobaltate

14335-33-2

[D3]phosphoric acid

A

CH2CHCH(CH2CH2D)Co(CO)3

B

CH(CH3)CHCH(CH2D)Co(CO)3

Conditions

Conditions	Yield
With CH2CHCH2CHCH2 In not given mechanism discussed;;	A n/a B 10%
With CH2CHCH2CHCH2 In not given mechanism discussed;;	A n/a B 10%

...Expand

14878-26-3

potassium tetracarbonylcobaltate

591-93-5

1,4-Pentadiene

7789-20-0

water-d2

14335-33-2

[D3]phosphoric acid

A

CH2CHCH(CH2CH2D)Co(CO)3

B

CH(CH3)CHCH(CH2D)Co(CO)3

Conditions

Conditions	Yield
In water-d2 mechanism discussed;;	A n/a B 5%
In water-d2 mechanism discussed;;	A n/a B 5%

...Expand

potassium cyanide

14335-33-2

[D3]phosphoric acid

3017-23-0

hydrogen cyanide

Conditions

Conditions	Yield
In neat (no solvent) vac. system.;
In neat (no solvent) action of perdeuterophosphoric acid on potassium cyanide in vac.;
With P2O5 In neat (no solvent) action of D3PO4 (with excess P2O5 added) on KCN in vac.;

584-08-7

potassium carbonate

14335-33-2

[D3]phosphoric acid

13761-79-0

deuterated potassium dihydrogen phosphate

Conditions

Conditions	Yield
prior synthesis carbonate dehydration for 2 h at 150°C;

sodium azide

14335-33-2

[D3]phosphoric acid

14989-19-6

hydrazoic acid

Conditions

Conditions	Yield
In neat (no solvent) mixing (excess of NaN3); not pure; mass spectroscopy;
In further solvent(s) NaN3 reacted with excess D3PO4 under vac.; mass spectrum;
distn., FTIR anal. of purity;

silver cyanide

14335-33-2

[D3]phosphoric acid

C(2)H(14)N

Conditions

Conditions	Yield
adding H3PO4 to KC(15)N in vac., condensing gas evolved;

iron sulfide

14335-33-2

[D3]phosphoric acid

13536-94-2

deuterium sulfide

Conditions

Conditions	Yield
In water-d2 reaction of P-compd. soln. with Fe-compd. in deuterated vac. line;

7789-20-0

water-d2

zinc sulfide

14335-33-2

[D3]phosphoric acid

13536-94-2

deuterium sulfide

Conditions

Conditions	Yield
In water-d2 condensing (-196°C, on a vac. line); vac. distn. (-20°C);

...Expand

773837-37-9

sodium cyanide

14335-33-2

[D3]phosphoric acid

3017-23-0

hydrogen cyanide

Conditions

Conditions	Yield
In water-d2 slow addn. of NaCN/D2O to stirred soln. of (2)H3PO4/D2O; dried (P2O5);
In water-d2 in vac.; trap-to-trap distn.;

3996-15-4

sodium formate

14335-33-2

[D3]phosphoric acid

920-42-3

dideuterioformic acid

Conditions

Conditions	Yield
In neat (no solvent) distillation of DCOONa with an excess of D3PO4;;

590-28-3

potassium cyanate

14335-33-2

[D3]phosphoric acid

10357-59-2

deuterio-isocyanic acid

Conditions

Conditions	Yield
In water-d2 vac.; vapor condensation, distillation;
In not given byproducts: D2O; distn.;

rubidium carbonate

14335-33-2

[D3]phosphoric acid

13775-96-7

deuterated rubidium dihydrogen phosphate

Conditions

Conditions	Yield
prior synthesis carbonate dehydration for 2 h at 350°C;
byproducts: CO2, D2O;
byproducts: D2O, CO2;
byproducts: (2H)2O, CO2;

14067-21-1

ammonium-d4 deuteroxide

14335-33-2

[D3]phosphoric acid

14989-27-6

deuterated ammonium dihydrogen phosphate

Conditions

Conditions	Yield
byproducts: D2O;

102-54-5

ferrocene

14335-33-2

[D3]phosphoric acid

ferrocene-d10

Conditions

Conditions	Yield
In 1,4-dioxane 3 fold 3 h heating of Fe(C5H5)2 with 10 fold excess of (2)H3PO4 in abs. dioxane at 110-120°C;; 98.1 % deuterated Fe(C5H5)2;;

potassium deuterohydroxide

14335-33-2

[D3]phosphoric acid

13761-79-0

deuterated potassium dihydrogen phosphate

disodium tetracarbonylosmate

14335-33-2

[D3]phosphoric acid

(2)H2Os(CO)4

Conditions

Conditions	Yield
In further solvent(s) high-vacuum line;

Phosphoric acid-d3 Chemical Properties

Phosphoric acid-d3 Uses

Phosphoric acid-d3 Safety Profile

Phosphoric acid-d3 Specification