Piperazine citrate supplier

Name
PIPERAZINE CITRATE
EINECS 205-622-8
CAS No. 144-29-6
Density 0.741[at 20℃]
Solubility 54g/L at 24℃
Melting Point 183-187 °C
Formula 2(C₆H₈O₇)^.3(C₄H₁₀N₂)
Boiling Point 812.2 °C at 760 mmHg
Molecular Weight 278.262
Flash Point 445 °C
Transport Information
Appearance White crystalline powder
Safety 26
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Oxyzin (syrup);Oxucide;Ascarex Syrup;Parazine;Vermizine (elixir);Helmezine;Pipizan;Pinozan;Bryrel;Piperazine citrate salt;Tripiperazine dicitrate;Pin-Tega;Tasnon;Vermago;Multifuge;
PSA 336.44000
LogP -2.98660

Piperazine citrate Consensus Reports

Reported in EPA TSCA Inventory.

Piperazine citrate Specification

The Piperazine citrate, with the CAS registry number 144-29-6, is also known as Tripiperazine dicitrate. It belongs to the product category of Piperidines, Piperidones, Piperazines. Its EINECS number is 205-622-8. This chemical's molecular formula is 2(C₆H₈O₇)^.3(C₄H₁₀N₂) and molecular weight is 642.66. What's more, its systematic name is Piperazine 2-hydroxy-1,2,3-propanetricarboxylate (3:2). Its classification codes are: (1)Anthelmintics; (2)Anti-Infective Agents; (3)Antiparasitic Agents; (4)Drug / Therapeutic Agent; (5)Human Data.

Physical properties of Piperazine citrate are: (1)# of Rule of 5 Violations: 3; (2)ACD/LogD (pH 5.5): -9.95; (3)ACD/LogD (pH 7.4): -13.42; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 1.00; (7)ACD/KOC (pH 7.4): 1.00; (8)#H bond acceptors: 20; (9)#H bond donors: 14; (10)#Freely Rotating Bonds: 12; (11)Polar Surface Area: 336.44 Å²; (12)Flash Point: 445 °C; (13)Enthalpy of Vaporization: 134.43 kJ/mol; (14)Boiling Point: 812.2 °C at 760 mmHg; (15)Vapour Pressure: 1.51E-30 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: OC(=O)C(O)(CC(O)=O)CC(O)=O.OC(=O)C(O)(CC(O)=O)CC(O)=O.C1CNCCN1.C1CNCCN1.C1CNCCN1
(2)Std. InChI: InChI=1S/2C6H8O7.3C4H10N2/c2*7-3(8)1-6(13,5(11)12)2-4(9)10;3*1-2-6-4-3-5-1/h2*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);3*5-6H,1-4H2
(3)Std. InChIKey: JDDHUROHDHPVIO-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	LDLo	oral	260mg/kg/3D-I (260mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: COMA BEHAVIORAL: HEADACHE	Lancet. Vol. 1, Pg. 895, 1967.
infant	TDLo	unreported	500mg/kg/2D (500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA	Indian Pediatrics. Vol. 18, Pg. 71, 1981.
man	TDLo	oral	150mg/kg/5D (150mg/kg)	SENSE ORGANS AND SPECIAL SENSES: DIPLOPIA: EYE BEHAVIORAL: TREMOR GASTROINTESTINAL: NAUSEA OR VOMITING	JAMA, Journal of the American Medical Association. Vol. 161, Pg. 515, 1956.
mouse	LD50	intraperitoneal	3548mg/kg (3548mg/kg)	BEHAVIORAL: EXCITEMENT SKIN AND APPENDAGES (SKIN): SWEATING: OTHER	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 274, Pg. 253, 1985.
mouse	LD50	oral	8500mg/kg (8500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: ATAXIA	Journal of Medicinal Chemistry. Vol. 6, Pg. 336, 1963.
mouse	LDLo	intravenous	100mg/kg (100mg/kg)		Compilation of LD50 Values of New Drugs.
rabbit	LDLo	intravenous	175mg/kg (175mg/kg)		Compilation of LD50 Values of New Drugs.
rat	LD50	oral	11200mg/kg (11200mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Journal of Medicinal Chemistry. Vol. 6, Pg. 336, 1963.

Product Name

PIPERAZINE CITRATE

Piperazine citrate Consensus Reports

Piperazine citrate Specification

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