5-(chloromethyl)-6-propyl-1,3-benzodioxole
Diethylene glycol monobutyl ether
Piperonyl butoxide
Conditions | Yield |
---|---|
Stage #1: Diethylene glycol monobutyl ether With sodium hydroxide In water Reflux; Stage #2: 5-(chloromethyl)-6-propyl-1,3-benzodioxole In water for 5h; Reflux; | 75% |
With sodium hydroxide at 30℃; for 5h; | 230 g |
Conditions | Yield |
---|---|
With benzene | |
With Diethylene glycol monobutyl ether | |
With benzene |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: water; hydrochloric acid 2: benzene View Scheme |
Piperonyl butoxide
Conditions | Yield |
---|---|
With N,N,N,N-tetraethylammonium tetrafluoroborate In acetonitrile electrolysis; Yield given; |
Conditions | Yield |
---|---|
With hydrogenchloride In water; benzene |
IUPAC Name: 5-[2-(2-Butoxyethoxy)ethoxymethyl]-6-propyl-1,3-benzodioxole
Empirical Formula: C19H30O5
Molecular Weight: 338.4385
Index of Refraction: 1.502
Molar Refractivity: 93.81 cm3
Molar Volume: 317.3 cm3
Surface Tension: 38.9 dyne/cm
Density: 1.066 g/cm3
Flash Point: 165.3 °C
Enthalpy of Vaporization: 62.12 kJ/mol
Boiling Point: 396.2 °C at 760 mmHg
Vapour Pressure: 3.98E-06 mmHg at 25 °C
Appearance: Light Yellow Liquid
EINECS: 200-076-7
storage temp.: 0-6 °C
Water Solubility: <0.1 g/100 mL at 18 ºC
Stability: Stable. Combustible. Incompatible with oxidizing agents.
Product Categories: Intermediates & Fine Chemicals; Pharmaceuticals
Classification Code of Piperonyl butoxide (CAS NO.51-03-6): Agricultural Chemical; Insect attractant, repellent and chemosterilant; Insecticide; Mutation data; Pesticide synergists; Pesticides; Reproductive Effect; Tumor data
Piperonyl butoxide (PBO) is a pesticide synergist, when added to insecticide mixtures, typically pyrethrin, pyrethroid, and carbamate insecticides, their potency is increased considerably.
Piperonyl butoxide is a potent cytochrome P450 and non-specific esterase inhibitor.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | oral | 7500uL/kg (7.5mL/kg) | American Journal of Tropical Medicine. Vol. 27, Pg. 339, 1947. | |
mouse | LD50 | oral | 2600mg/kg (2600mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Shokuhin Eiseigaku Zasshi. Food Hygiene Journal. Vol. 24, Pg. 268, 1983. |
mouse | LDLo | intraperitoneal | 1gm/kg (1000mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972. | |
rabbit | LD50 | oral | 2650mg/kg (2650mg/kg) | Yakkyoku. Pharmacy. Vol. 32, Pg. 605, 1981. | |
rabbit | LD50 | skin | 200mg/kg (200mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 907, 1966. | |
rat | LD50 | oral | 6150mg/kg (6150mg/kg) | Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969. | |
rat | LD50 | skin | > 7950mg/kg (7950mg/kg) | Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969. |
Hazard Codes: N,T
Risk Statements: 50/53-51/53-24
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R24:Toxic in contact with skin.
Safety Statements: 60-61-45-36/37/39-28A
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S28:After contact with skin, wash immediately with plenty of soap-suds.
RIDADR: UN 3082 9/PG 3
WGK Germany: 3
RTECS: XS8050000
HazardClass: 6.1(b)
PackingGroup: III
Piperonyl butoxide (CAS NO.51-03-6), its Synonyms are 1,3-Benzodioxole, 5-((2-(2-butoxyethoxy)ethoxy)methyl)-6-propyl- ; 2-(2-Butoxyethoxy)ethyl 6-propylpiperonyl ether ; 3,4-Methylendioxy-6-propylbenzyl-n-butyl-diaethylenglykolaether ; 3,4-Methylenedioxy-6-propylbenzyl n-butyl diethyleneglycol ether ; 3,4-Methylenedioxy-6-propylbenzyl n-butyldiethyleneglycol ether ; 3,4-Methylenedioxy-6-propylbenzyl-n-butyl-diaethylenglykolaether ; 5-(2-(2-Butoxyethoxy)ethoxymethyl)-6-propyl-1,3-benzodioxole ; 5-Propyl-4-(2,5,8-trioxa-dodecyl)-1,3-benzodioxol ; 5-Propyl-4-(2,5,8-trioxa-dodecyl)-1,3-benzodioxol [German] ; 6-(Propylpiperonyl)-butyl carbityl ether ; 6-(Propylpiperonyl)butylcarbityl ether ; 6-Propylpiperonyl butyl diethylene glycol ether .
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View