The Polycarbophil, with the CAS registry number 9003-97-8, is also known as Polyacrylic acid calcium salt cross-linked with divinyl glycol. What's more, its systematic name is Calcium polycarbophil. Its classification codes are: (1)Antidiarrheals; (2)Cathartics; (3)Drug / Therapeutic Agent; (4)Gastrointestinal Agents; (5)Laxative. This chemical is synthetic, loosely cross-linked, hydrophilic resin of the polycarboxylic type. It is marketed as a stool normalizer and it is used in the treatment of both constipation & diarrhea.
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LD50 | oral | 20gm/kg (20000mg/kg) | GASTROINTESTINAL: OTHER CHANGES | Pharmacotherapy Vol. 2, Pg. 18, 1982. |
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