• Name

  Propanoic acid, propylester

• EINECS 203-389-7
• CAS No. 106-36-5
• Article Data117
• CAS DataBase
• Density 0.886 g/cm³
• Solubility
• Melting Point -76 °C(lit.)
• Formula C₆H₁₂O₂
• Boiling Point 121.9 °C at 760 mmHg
• Molecular Weight 116.16
• Flash Point 19.4 °C
• Transport Information UN 3272 3/PG 2
• Appearance Clear colorless liquid
• Safety 24
• Risk Codes 10-20
• Molecular Structure
• Hazard Symbols Xn
• Synonyms Propionicacid, propyl ester (6CI,8CI);NSC 72022;Propyl propanoate;n-Propyl n-propanoate;n-Propyl propionate;
• PSA 26.30000
• LogP 1.34960

Synthetic route

71-23-8

propan-1-ol

106-36-5

propyl propionate

Conditions

Conditions	Yield
With dihydrogen peroxide; bromine In dichloromethane; water at 20℃; for 2h;	99%
With water; potassium iodide at 20℃; for 3h; Electrochemical reaction; Green chemistry;	72%
With calcium dichloride dihydrate; oxone; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; water In dichloromethane at 20℃; for 4h;	72%

123-38-6

propionaldehyde

106-36-5

propyl propionate

Conditions

Conditions	Yield
With [{(PhN)MeC(Nt-Bu)}AlMe(μ-OMe)]2 at 20℃; for 0.5h; Tishchenko-Claisen Dismutation; Inert atmosphere; Schlenk technique; Green chemistry;	99%
With aluminium propanolate
With Mg-tetrakis(methoxy)borate; mercury dichloride In diethyl ether
With Rh(PhBP3)(H)2(NCMe) In benzene-d6 at 20℃; for 0.0166667h; Tishchenko reaction; Inert atmosphere;

71-23-8

propan-1-ol

802294-64-0

propionic acid

106-36-5

propyl propionate

Conditions

Conditions	Yield
With Dowex 50Wx2 hydrogen form resin at 108 - 113℃; Reagent/catalyst; Autoclave; Large scale;	97.36%
With salicylic acid resin supported FeCl3 In benzene at 125℃; for 2.11667h;	95.8%
With Rhizomucor miehei lipase In n-heptane at 40℃; for 24h; Enzymatic reaction;	95.3%

21373-88-6, 16920-54-0

(PPh3)3CoH(N2)

637-27-4

phenyl propionate

A

53729-69-4, 21329-67-9

HCo(CO)(P(C6H5)3)3

B

106-36-5

propyl propionate

C

91583-66-3

phenoxotris(triphenylphosphine)cobalt(I)

D

74-84-0

ethane

E

7727-37-9

nitrogen

Conditions

Conditions	Yield
In toluene byproducts: H2; EtCO2Ph added to CoH(N2)(PPh3)3 in toluene in vac., reacted for 3 days at room temp.; liquid phase analysed by GLC; hexane added, ppt. filtered, washed with hexane, dried in vac., recrystd. from C6H6-hexane;	A n/a B 33% C 62% D 23% E 85%

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21373-88-6, 16920-54-0

(PPh3)3CoH(N2)

123-62-6

propionic acid anhydride

A

99668-70-9

Co(1+)*C2H5CO2(1-)=Co(OCOC2H5)

B

106-36-5

propyl propionate

C

74-84-0

ethane

D

7727-37-9

nitrogen

E

1333-74-0

hydrogen

Conditions

Conditions	Yield
In toluene in toluene at room temp. for 1 day;	A n/a B 28% C 26% D 84% E 15%

...Expand

25538-50-5

normal propyl hypochlorite

106-36-5

propyl propionate

Conditions

Conditions	Yield
In tetrachloromethane for 4h; Irradiation;	75%
In benzene Ambient temperature; Irradiation;	75%

16844-98-7

trimethylsilyl propionate

106-36-5

propyl propionate

Conditions

Conditions	Yield
With hydrogen; chromium(III) oxide; nickel(III) oxide

79-03-8

propionyl chloride

106-36-5

propyl propionate

Conditions

Conditions	Yield
With triphenylstannane

71-23-8

propan-1-ol

A

106-36-5

propyl propionate

B

123-38-6

propionaldehyde

Conditions

Conditions	Yield
With dodecacarbonyl-triangulo-triruthenium; diphenyl acetylene at 145℃; for 4h; Product distribution; Mechanism; other alcohols; other reagents; var. time;
With [Ru(1,2-bis(diphenylphosphino)benzene )(CO)2Cl2]; potassium tert-butylate; acetone In toluene at 100℃; for 6h;	A 68 %Chromat. B 8 %Chromat.
With [Ru(1,2-bis(diphenylphosphino)benzene )(CO)2Cl2]; potassium tert-butylate; acetone In toluene at 100℃; for 6h;	A 29 %Chromat. B 62 %Chromat.

614-45-9

tert-Butyl peroxybenzoate

4073-85-2

aluminium propanolate

A

71-23-8

propan-1-ol

B

106-36-5

propyl propionate

C

2315-68-6

propyl benzoate

D

75-65-0

tert-butyl alcohol

Conditions

Conditions	Yield
In benzene at 20℃; for 336h; Product distribution; Mechanism; other temperature and time;
20 deg C, 3 d, then 70 deg C, 30 h; Yield given. Yields of byproduct given;

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107-71-1

tert-butyl peroxyacetate

4073-85-2

aluminium propanolate

A

71-23-8

propan-1-ol

B

106-36-5

propyl propionate

C

109-60-4

1-Propyl acetate

D

75-65-0

tert-butyl alcohol

Conditions

Conditions	Yield
In benzene at 20℃; for 168h; Product distribution; Mechanism;

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74-85-1

ethene

201230-82-2

carbon monoxide

A

106-36-5

propyl propionate

B

123-38-6

propionaldehyde

C

802294-64-0

propionic acid

D

96-22-0

pentan-3-one

Conditions

Conditions	Yield
cobalt catalyst In butanone at 160℃; for 2.41667h; Yield given;
cobalt catalyst In ethanol at 160℃; Product distribution; other temperature, other solvent, other catalyst concentration, influence of water, effect of partial pressure of ethylene and carbon monooxide;

...Expand

760-32-7

diethylmethylsilane

A

106-36-5

propyl propionate

B

17680-28-3

methyldiethylchlorosilane

Conditions

Conditions	Yield
With propionyl chloride; bis(acetylacetonate)nickel(II) at 90℃; for 2h;	A 74 % Chromat. B 87 % Chromat.

554-12-1

propanoic acid methyl ester

A

67-56-1

methanol

B

71-23-8

propan-1-ol

C

106-36-5

propyl propionate

Conditions

Conditions	Yield
With hydrogen; <(Ph3P)(Ph2P)RuH2-K+*diglyme>2 In toluene at 90℃; under 4650.4 Torr; for 20h; Title compound not separated from byproducts;

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79-03-8

propionyl chloride

A

106-36-5

propyl propionate

B

17680-28-3

methyldiethylchlorosilane

Conditions

Conditions	Yield
With diethylmethylsilane; bis(acetylacetonate)nickel(II) at 90℃; for 2h;	A 79 % Chromat. B 87 % Chromat.

74-85-1

ethene

123-38-6

propionaldehyde

A

71-23-8

propan-1-ol

B

106-36-5

propyl propionate

C

14250-96-5, 16958-22-8, 623-36-9

2-methyl-2-pentenal

D

802294-64-0

propionic acid

E

96-22-0

pentan-3-one

Conditions

Conditions	Yield
With tris(triphenylphosphine)ruthenium(II) chloride at 210℃; for 18h; Product distribution; other aldehydes and olefines;

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71-23-8

propan-1-ol

123-62-6

propionic acid anhydride

106-36-5

propyl propionate

Conditions

Conditions	Yield
sulfuric acid

201230-82-2

carbon monoxide

56-81-5

glycerol

A

109-99-9

tetrahydrofuran

B

71-23-8

propan-1-ol

C

106-36-5

propyl propionate

D

111-43-3

Dipropyl ether

E

61940-71-4

3-n-propoxy-1,2-propanediol

F

71-36-3

butan-1-ol

Conditions

Conditions	Yield
With diiodidotetracarbonylruthenium(II); hydrogen In water at 200℃; for 8h; Product distribution; other conditions; var. polyols and sugars;	A 10.2 mmol B 61.3 mmol C 8.5 mmol D 4.9 mmol E 42.3 mmol F 6.2 mmol

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123-38-6

propionaldehyde

A

106-36-5

propyl propionate

B

802294-64-0

propionic acid

C

96-22-0

pentan-3-one

D

78-93-3

butanone

Conditions

Conditions	Yield
With chromium-zinc-manganese oxide; water at 300℃; Mechanism; Product distribution; other aliphatic aldehydes; var. temp.;

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25538-50-5

normal propyl hypochlorite

100-52-7

benzaldehyde

A

106-36-5

propyl propionate

B

2315-68-6

propyl benzoate

Conditions

Conditions	Yield
In benzene Ambient temperature; Irradiation;

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25538-50-5

normal propyl hypochlorite

123-72-8

butyraldehyde

A

106-36-5

propyl propionate

B

105-66-8

propyl butanoate

Conditions

Conditions	Yield
In benzene Ambient temperature; Irradiation;

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Propyl propionate Chemical Properties

Propyl propionate Uses

Propyl propionate Toxicity Data With Reference

Propyl propionate Consensus Reports

Propyl propionate Safety Profile