Quercetin supplier | CasNO.117-39-5

Name
Quercetin
EINECS 204-187-1
CAS No. 117-39-5
Article Data243
CAS DataBase
Density 1.799 g/cm³
Solubility <0.1 g/100 mL at 21 ºC in water
Melting Point 314-317 ºC
Formula C₁₅H₁₀O₇
Boiling Point 642.4 ºC at 760 mmHg
Molecular Weight 302.24
Flash Point 248.1 ºC
Transport Information
Appearance Yellow to green yellow crystalline powde
Safety 45-36-26
Risk Codes 25-36/37/38
Molecular Structure
Hazard Symbols T,Xi
Synonyms 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-;Quercetin content;Cyanidelonon 1522;3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-on;3,5,7,3,4-Pentahydroxyflavone;Quercetine;Quercetol;3,3',4',5,7-pentahydroxyflavone;Quercetin 99%;Sophoretin;C.I. natural yellow 10 & 13;C.I. Natural Yellow 10;Quertin;C.I. 75670;Quertine;t-Gelb bzw. grun 1;3,4,5,7-Tetrahydroxyflavan-3-ol;4H-1-Benzopyran-4-one, 2- (3,4-dihydroxyphenyl)-3,5,7-trihydroxy-;Xanthaurine;3,5,7,3, 4-Pentahydroxyflavone;Flavin meletin;Flavone, 3,3,4,5,7-pentahydroxy-;2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Flavone, 3,4,5,5,7-pentahydroxy-;3,3,4,5,7-Pentahydroxyflavone;2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one;
PSA 131.36000
LogP 1.98800

Synthetic route

: 153-18-4
rutin

: 117-39-5
quercetol

Conditions

Conditions	Yield
With hydrogenchloride; methanol for 3h; Heating;	96%
With water at 100℃; Kinetics; Ionic liquid;	90%
With sulfuric acid; water at 20℃; for 0.166667h;	89%

: 7647-01-0
hydrogenchloride

: 187221-65-4
quercetin triphenylantimony complex

A: 117-39-5
quercetol

B: 594-31-0, 34716-91-1, 20265-29-6
triphenylantimony dichloride

Conditions

Conditions	Yield
heating (3 h, water bath); soln. pouring into Petri dish, solid extraction by benzene;	A 75% B 88%

...Expand

: 95412-48-9
6,8-dibromoquercetin

: 117-39-5
quercetol

Conditions

Conditions	Yield
With sodium sulfite In water at 60℃; for 18h; Green chemistry;	87%

: 1244-78-6
2-(3,4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-4H-4-chromenone

: 117-39-5
quercetol

Conditions

Conditions	Yield
With boron tribromide In dichloromethane for 6h; Heating;	83%
With trimethylsilyl iodide In methanol at 35℃; for 96h; Inert atmosphere;

: 482-36-0
Hyperoside

A: 10257-28-0
D-Galactose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With sulfuric acid at 100℃; for 1h;	A n/a B 68%
With grape snail enzymes
With rhamnodiastase

: antoside

A: 2280-44-6
D-Glucose

B: 73-34-7
L-rhamnose

C: 117-39-5
quercetol

Conditions

Conditions	Yield
With sulfuric acid at 100℃; for 2h;	A n/a B n/a C 68%
With sulfuric acid at 100℃; for 2h;	A n/a B n/a C 47%

...Expand

: 491-50-9, 36450-05-2, 59985-52-3
quercetin 7-O-β-D-glucopyranoside

: 117-39-5
quercetol

Conditions

Conditions	Yield
Acid hydrolysis;	68%
With sulfuric acid for 1h; Heating;

: 491-50-9, 36450-05-2, 59985-52-3
quercetin 7-O-β-D-glucopyranoside

A: 50-99-7
D-glucose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With water Acidic conditions;	A n/a B 65%
With water Acidic conditions;

: 482-35-9
isoquercetin

A: 2280-44-6
D-Glucose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With sulfuric acid	A n/a B 64.3%
Product distribution; object of study - products of acid hydrolysis;
With 2M HCl In hydrogenchloride at 90℃; for 1h; Product distribution; other reagent;

: 482-36-0
Hyperoside

A: 59-23-4
D-Galactose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With water Acidic conditions;	A n/a B 64%
Acidic conditions;
Acidic aq. solution;

: 6743-88-0, 22255-13-6, 72581-59-0, 94131-44-9
guaijaverin

A: 87-72-9, 608-45-7, 608-46-8, 608-47-9, 2460-44-8, 6748-95-4, 6763-34-4, 7261-26-9, 7283-06-9, 7283-07-0, 7296-55-1, 7296-56-2, 7296-58-4, 7296-59-5, 7296-60-8, 7296-61-9, 7296-62-0, 7322-30-7, 10257-31-5, 10257-32-6, 10257-33-7, 10257-34-8, 10257-35-9, 19982-83-3, 20242-88-0, 28697-53-2, 36562-42-2, 41546-41-2, 89299-64-9, 107655-34-5, 115794-06-4, 115794-07-5, 130550-15-1, 130606-21-2
L-(+)-arabinose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With sulfuric acid for 3h;	A n/a B 63.5%

: 482-35-9
isoquercetin

: 117-39-5
quercetol

Conditions

Conditions	Yield
Acidic conditions;	63.3%
With oxonium
With hydrogenchloride; ethanol for 4h; Heating;

: 482-36-0
Hyperoside

: 117-39-5
quercetol

Conditions

Conditions	Yield
Acidic conditions;	63.3%
Acid hydrolysis;
With hydrogenchloride In water for 0.5h; Reflux;

: 153-18-4
rutin

A: 552-74-9, 26184-96-3, 47235-47-2, 56906-86-6, 56942-81-5, 68398-81-2, 68567-48-6, 68567-49-7, 75828-90-9, 59246-67-2
6-O-α-L-rhamnopyranosyl-β-D-glucopyranose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With α-L-rhamnosyl-β-D-glucosidase from Aspergillus niger K2 in Pichia pastoris In aq. phosphate buffer; dimethyl sulfoxide at 35 - 100℃; for 24h; pH=5; Enzymatic reaction;	A 63% B n/a
With rhamnodiastase Reactivity; Enzymatic reaction;
With rutinosidase In water Enzymatic reaction;

: 458-35-5
coniferol

: 153-18-4
rutin

A: C22H32O12

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With α-L-rhamnosyl-β-D-glucosidase from Aspergillus niger In dimethyl sulfoxide at 35℃; for 8h; pH=5; Enzymatic reaction;	A 60% B n/a

...Expand

: 215257-15-1
3,3',4',5,7-pentahydroxy flavanone

: 117-39-5
quercetol

Conditions

Conditions	Yield
With potassium pyrosulfite In ethanol at 100℃;	50%
With pyridine; air for 20h; Heating;

: 153-18-4
rutin

A: 3615-41-6
L-Rhamnose

B: 50-99-7
D-glucose

C: 117-39-5
quercetol

Conditions

Conditions	Yield
With sulfuric acid; water	A n/a B n/a C 47%
With sulfuric acid
With hydrogenchloride; water In methanol at 100℃; for 2h;

...Expand

: 492-00-2
3,7-dihydroxyflavone

: 616-38-6
carbonic acid dimethyl ester

: 117-39-5
quercetol

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 90℃; for 72h;	28%

: 501-94-0
p-hydroxyphenethyl alcohol

: 153-18-4
rutin

A: 26184-96-3, 552-74-9, 47235-47-2, 56906-86-6, 56942-81-5, 59246-67-2, 68398-81-2, 68567-48-6, 68567-49-7, 75828-90-9
rutinose

B: 117-39-5
quercetol

C: 2-(4-hydroxyphenyl)ethyl β-rutinoside

Conditions

Conditions	Yield
Stage #1: p-hydroxyphenethyl alcohol; rutin In methanol at 40℃; for 30h; Stage #2: With water In methanol for 0.166667h; Reflux; regioselective reaction;	A n/a B n/a C 24%

...Expand

: 603-61-2
tamarixetin

: 117-39-5
quercetol

Conditions

Conditions	Yield
With water; hydrogen iodide; acetic anhydride at 150℃;

: 4382-17-6
3,3'-di-O-methylquercetin

: 117-39-5
quercetol

Conditions

Conditions	Yield
With water; hydrogen iodide at 150℃;

: 859439-36-4
2-benzo[1,3]dioxol-5-yl-3-hydroxy-5,7-dimethoxy-chromen-4-one

: 117-39-5
quercetol

Conditions

Conditions	Yield
With aluminium trichloride; chlorobenzene at 130℃; Erwaermen des Reaktionsgemisches mit wss. HCl;

: 90-19-7
rhamnetin

: 117-39-5
quercetol

: 572-30-5
avicularin

A: 10323-20-3
D-Arabinose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With hydrogenchloride for 2h; Heating;

: 482-35-9
isoquercetin

A: 492-61-5
β-D-glucose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
Product distribution; acid hydrolysis;

: 865688-88-6
quercitrin

A: 73-34-7, 87-96-7, 488-79-9, 551-63-3, 609-01-8, 643-17-4, 643-18-5, 4164-09-4, 6014-42-2, 6155-36-8, 6189-71-5, 6696-41-9, 6736-43-2, 13224-93-6, 22611-09-2, 28161-49-1, 28161-50-4, 28161-52-6, 45864-36-6, 63814-64-2, 71116-59-1, 71116-61-5, 72598-05-1, 87936-88-7, 87936-89-8, 97466-79-0, 116908-82-8, 120442-60-6, 123484-22-0, 133576-32-6
D-rhamnose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
hesperidinase

: 522-12-3, 22324-77-2, 124827-82-3
quercitrin

A: 73-34-7
L-rhamnose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With hydrogenchloride
With sulfuric acid

: 6743-88-0, 22255-13-6, 72581-59-0, 94131-44-9
quercetin-3-arabinoside

A: 87-72-9, 608-45-7, 608-46-8, 608-47-9, 2460-44-8, 6748-95-4, 6763-34-4, 7261-26-9, 7283-06-9, 7283-07-0, 7296-55-1, 7296-56-2, 7296-58-4, 7296-59-5, 7296-60-8, 7296-61-9, 7296-62-0, 7322-30-7, 10257-31-5, 10257-32-6, 10257-33-7, 10257-34-8, 10257-35-9, 19982-83-3, 20242-88-0, 28697-53-2, 36562-42-2, 41546-41-2, 89299-64-9, 107655-34-5, 115794-06-4, 115794-07-5, 130550-15-1, 130606-21-2
L-(+)-arabinose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With hydrogenchloride boiling water bath;

: 55696-57-6, 124151-38-8
manghaslin

A: 2280-44-6
D-Glucose

B: 73-34-7, 87-96-7, 488-79-9, 551-63-3, 609-01-8, 643-17-4, 643-18-5, 4164-09-4, 6014-42-2, 6155-36-8, 6189-71-5, 6696-41-9, 6736-43-2, 13224-93-6, 22611-09-2, 28161-49-1, 28161-50-4, 28161-52-6, 45864-36-6, 63814-64-2, 71116-59-1, 71116-61-5, 72598-05-1, 87936-88-7, 87936-89-8, 97466-79-0, 116908-82-8, 120442-60-6, 123484-22-0, 133576-32-6
L-rhamnose

C: 117-39-5
quercetol

Conditions

Conditions	Yield
With sulfuric acid for 3h; Product distribution; Heating; hydrolysis for structure determination;sugar products were identified as their trimethylsilyl derivatives by GC-MS;

...Expand

: 572-30-5, 5041-68-9, 72581-58-9, 119786-64-0, 137332-22-0
3,3',4',5,7-pentahydroxyflavone 3-O-arabogluocopyranoside

A: 532-20-7, 613-83-2, 7261-25-8, 7687-39-0, 13221-22-2, 14795-83-6, 15761-67-8, 20074-49-1, 25545-03-3, 25545-04-4, 32445-75-3, 34436-17-4, 36441-93-7, 36468-53-8, 37110-85-3, 37388-49-1, 38029-69-5, 40461-77-6, 40461-89-0, 41546-19-4, 41546-20-7, 41546-21-8, 41546-26-3, 41546-29-6, 41546-30-9, 41546-31-0, 126872-16-0, 131064-98-7
D-arabinofuranose

B: 117-39-5
quercetol

Conditions

Conditions	Yield
With hydrogenchloride for 0.25h;

: 117-39-5
quercetol

: 108-24-7
acetic anhydride

: 1064-06-8
3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one

Conditions

Conditions	Yield
With pyridine at 130 - 140℃;	100%
With pyridine at 140 - 145℃; for 4h;	97.5%
With pyridine at 70℃; for 6h;	95%

: 117-39-5
quercetol

: C30H20O14Se

Conditions

Conditions	Yield
With hydrogenchloride; selenium(IV) oxide In ethanol; water at 60℃; for 12h; Inert atmosphere;	99.2%

: 117-39-5
quercetol

: 108-24-7
acetic anhydride

: 7622-90-4
quercetin-3',4',5,7-tetraacetate

Conditions

Conditions	Yield
With magnesium In neat (no solvent) at 25℃; for 3.5h; Temperature;	98%

: 117-39-5
quercetol

glucosidase: glucosidase

: 482-35-9
isoquercetin

Conditions

Conditions	Yield
With 1% disodium hydrogen phosphate-sodium citrate; 35-40% glucosyltransferase at 40 - 45℃; Enzymatic reaction;	97.2%

: 117-39-5
quercetol

: 98-88-4
benzoyl chloride

: 120036-90-0
2-(3,4-bis(benzoyloxy)phenyl)-4-oxo-4H-chromene-3,5,7-triyl tribenzoate

Conditions

Conditions	Yield
With pyridine In dichloromethane at 20℃; for 3h;	97%
With pyridine at 22 - 24℃; for 4h;	92%
With pyridine at 60℃;	56%
With sodium hydroxide

: 117-39-5
quercetol

: 97-72-3
2-Methylpropionic anhydride

: 102607-68-1
2-(3,4-bis(isobutyryloxy)phenyl)-4-oxo-4H-chromene-3,5,7-triyl tris(2-methylpropanoate)

Conditions

Conditions	Yield
With pyridine for 2h; Reflux;	97%
In pyridine Ambient temperature;	0.43 g

: 117-39-5
quercetol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 265975-30-2
3,3',4',5,7-penta-O-tert-butyldimethylsilylquercetin

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 6h; silylation;	97%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 5h;

: 117-39-5
quercetol

: 100-39-0
benzyl bromide

: 13157-90-9
2-[3,4-bis(phenylmethoxy)phenyl]-3,5,7-tris(phenylmethoxy)chromen-4-one

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 72h;	95%
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 4h; Etherification;	89%
Stage #1: quercetol; benzyl bromide With potassium carbonate In N,N-dimethyl-formamide at 20 - 70℃; for 15h; Stage #2: With water In N,N-dimethyl-formamide at 20℃; for 1h;	80%

: 117-39-5
quercetol

: 100-44-7
benzyl chloride

: 13157-90-9
2-[3,4-bis(phenylmethoxy)phenyl]-3,5,7-tris(phenylmethoxy)chromen-4-one

Conditions

Conditions	Yield
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate at 20℃; for 35h; Inert atmosphere;	95%
With tetrabutylammomium bromide; potassium carbonate In 1-methyl-pyrrolidin-2-one; acetone at 85 - 90℃; for 24h;	93%
With potassium carbonate; Aethyl-dipropyl-benzyl-ammonium In N,N,N,N,N,N-hexamethylphosphoric triamide for 35h; Inert atmosphere;	90%
With tetrabutylammomium bromide; potassium carbonate In 1-methyl-pyrrolidin-2-one; acetone at 75℃; for 24h; Inert atmosphere;	87%
With potassium carbonate; N,N-dimethyl-formamide at 20℃; for 12h;	15%

: 117-39-5
quercetol

: 127-09-3
sodium acetate

: 108-24-7
acetic anhydride

: 1064-06-8
3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one

Conditions

Conditions	Yield
Reflux; Inert atmosphere;	95%

...Expand

: 14049-94-6
ZnCl2(1,10-phenanthroline)

: 117-39-5
quercetol

: [(1,10-phenanthroline)Zn(Quercetin)Cl].3H2O

Conditions

Conditions	Yield
With triethylamine In ethanol; water at 20℃; for 0.166667h; Inert atmosphere;	94%

: 117-39-5
quercetol

: 30048-34-1
2-(3',4'-dihydroxybenzoyloxy)-4,6-dihydroxybenzoic acid

Conditions

Conditions	Yield
With oxygen; tetraethylammonium tosylate In N,N-dimethyl-formamide Mechanism; electrolysis at -1.0 V, Au electrode;	93%
With MES buffer; quercetinase EC 1.31.11.24 In dimethyl sulfoxide for 1h; pH=6;
With recombinant quercetinase from Aspergillus japonicus; oxygen In aq. buffer at 40 - 60℃; for 360h; pH=5; Reagent/catalyst; pH-value; Enzymatic reaction;

: 14491-36-2
(2,2'-bipyridyl)dichlorozinc(II)

: 117-39-5
quercetol

: [(2,2'-bipyridine)Zn(Quercetin)Cl].3H2O

Conditions

Conditions	Yield
With triethylamine In ethanol; water at 20℃; for 0.166667h; Inert atmosphere;	92%

: 14783-09-6
dichloro(1,10-phenanthroline) copper(II)

: 117-39-5
quercetol

: [(1,10-phenanthroline)Cu(Quercetin)Cl].3H2O

Conditions

Conditions	Yield
With triethylamine In ethanol; water at 20℃; for 0.166667h; Inert atmosphere;	92%

: 117-39-5
quercetol

: 2106-10-7
1-deoxy-1-fluoro-α-D-glucose

: quercetin 7-α-O-glucoside

Conditions

Conditions	Yield
With α-glucosidase from sulfolobus solfataricus In dimethyl sulfoxide at 45℃; for 2h; pH=9; Enzymatic reaction;	92%

: 117-39-5
quercetol

: 31273-65-1
2-(3,4-dihydroxy-5-sulfophenyl)-3,5,7-trihydroxy-4H-benzopyran-4-one

Conditions

Conditions	Yield
With sulfuric acid at 80℃; for 2h;	90%

: 117-39-5
quercetol

A: 116097-14-4
C15H7O16S3(3-)*3K(1+)

B: 90332-36-8, 119560-46-2
quercetin-3,7,3',4'-tetrasulphate potassium

Conditions

Conditions	Yield
With potassium acetate; tetra(n-butyl)ammonium hydrogensulfate; dicyclohexyl-carbodiimide In pyridine at 25℃; for 288h;	A 89% B n/a

: 2051-90-3
Dichlorodiphenylmethane

: 117-39-5
quercetol

: 357194-03-7
2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3,5,7-trihydroxychromen-4-one

Conditions

Conditions	Yield
In diphenylether at 175℃; for 2h;	89%
In diphenylether at 175℃; for 2h;	89%
In diphenylether at 175℃; for 0.5h; Inert atmosphere; regioselective reaction;	86%

: 64-17-5
ethanol

: 117-39-5
quercetol

: 102788-22-7
2-(3,4-Dihydroxy-phenyl)-2-ethoxy-3,3,5,7-tetrahydroxy-chroman-4-one

Conditions

Conditions	Yield
With oxygen; copper dichloride at 20℃; for 10h;	88%
With phosphate buffer at 80℃; for 7h; Irradiation;	3 mg
With phosphate buffer at 30℃; for 4h; Irradiation; enzyme solution from red clover (leaves and stems);	2 mg

: 117-39-5
quercetol

: 75-03-6
ethyl iodide

: 82547-07-7
2-(3,4-diethoxyphenyl)-3,5,7-triethoxy-4H-chromen-4-one

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 45℃; for 12h; Inert atmosphere;	87%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 15h; Inert atmosphere;	82%
With tetraethylammonium fluoride In N,N-dimethyl-formamide for 20h;	70%
With potassium hydroxide

: 117-39-5
quercetol

: 3282-30-2
pivaloyl chloride

: 2-(3,4-bis(pivaloyloxy)phenyl)-4-oxo-4H-chromene-3,5,7-triyl tris(2,2-dimethylpropanoate)

Conditions

Conditions	Yield
With pyridine for 2h; Reflux;	87%
With pyridine for 16h; Ambient temperature;	67%

: 117-39-5
quercetol

: 6-bromo-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one

Conditions

Conditions	Yield
With bromine In 1,4-dioxane at 20 - 22℃; for 2h;	86.1%
Stage #1: quercetol With N-Bromosuccinimide; sodium hydroxide In methanol; water at 20℃; for 0.166667h; Inert atmosphere; Green chemistry; Stage #2: With hydrogenchloride; sodium dithionite In methanol; water at 20℃; Inert atmosphere; Green chemistry;	400 mg
Multi-step reaction with 3 steps 1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 60 °C / Inert atmosphere 2: N-Bromosuccinimide / dichloromethane / -40 °C / Inert atmosphere 3: boron trichloride / dichloromethane; hexane / 2.5 h / -20 °C / Inert atmosphere; Reflux View Scheme
With bromine In 1,4-dioxane at 24.84℃;

: 117-39-5
quercetol

: 74-88-4
methyl iodide

: 1247-97-8
pentamethyl quercetin

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 35℃; for 12h; Inert atmosphere;	86%
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 12h;	84%
With potassium carbonate In acetone for 24h; Reflux;	82%

: 117-39-5
quercetol

: 3,5,7-trihydroxy-2-(3,4-dihydroxyphenyl-2,5,6-D3)-4H-1-benzopyran-4-one-6,8-D2

Conditions

Conditions	Yield
With boron trifluoride; [D3]phosphoric acid In water-d2 at 55℃; for 48h; deuteration;	86%
Stage #1: quercetol With [D]-sodium hydroxide; platinum on activated charcoal; water-d2 at 130℃; for 9h; Inert atmosphere; Stage #2: With formic acid at 130℃; for 1h; Inert atmosphere;	63%

: 1186389-75-2
C35H56O5

: 117-39-5
quercetol

: 1186389-71-8
C50H64O11

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 60℃; Inert atmosphere;	86%

: 75-18-3
dimethylsulfide

: 117-39-5
quercetol

: 1245-15-4
retusin

Conditions

Conditions	Yield
With potassium hydroxide In water; acetone	86%

: 117-39-5
quercetol

: 147-85-3
L-proline

: quercetin L-proline cocrystals(1:2)

Conditions

Conditions	Yield
In ethanol at 50℃;	85.5%

Quercetin Chemical Properties

Molecular Structure:

Molecular Formula: C₁₅H₁₀O₇
Molecular Weight: 302.2357
IUPAC Name: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
Synonyms of Quercetin (CAS NO.117-39-5): 3',4',5,7-Tetrahydroxyflavan-3-ol ; 3,3',4',5,7-Pentahydroxyflavone ; 3,5,7,3',4'-Pentahydroxyflavone ; 3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-on ; 5-18-05-00494 (Beilstein Handbook Reference) ; AI3-26018 ; BRN 0317313 ; C.I. 75670 ; C.I. Natural Yellow 10 ; CCRIS 1639 ; CI 75670 ; CI Natural Yellow 10 ; EINECS 204-187-1 ; Flavin meletin ; Flavone, 3,3',4',5,7-pentahydroxy- ; HSDB 3529 ; Kvercetin ; Kvercetin [Czech] ; NCI-C60106 ; NSC 9219 ; NSC 9221 ; Quercetin content ; Sophoretin ; T-Gelb bzw. grun 1 ; UNII-9IKM0I5T1E ; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy- ; Natural Yellow 10
CAS NO: 117-39-5
Classification Code: Antioxidants ; Mutation data ; Natural Product ; Protective Agents ; Reproductive Effect ; Tumor data
Melting point: 314-317°C
Index of Refraction: 1.823
Molar Refractivity: 73.31 cm³
Molar Volume: 167.9 cm³
Surface Tension: 114.8 dyne/cm
Density: 1.799 g/cm³
Flash Point: 248.1 °C
Enthalpy of Vaporization: 98.26 kJ/mol
Boiling Point: 642.4 °C at 760 mmHg
Vapour Pressure: 4.24E-17 mmHg at 25°C

Quercetin Uses

Quercetin (CAS NO.117-39-5) has demonstrated significant anti-inflammatory activity by inhibiting both manufacture and release of histamine and other allergic/inflammatory mediators.In addition, it exerts potent antioxidant activity and vitamin C-sparing action. It has also been claimed that quercetin reduces blood pressure in hypertensive subjects. An in-vitro study on fat cells suggested that quercetin and resveratrol may have a synergistic anti-obesity effect.

Quercetin Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	3gm/kg (3000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64, Pg. 186, 1968.
mouse	LD50	intravenous	18mg/kg (18mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02589,
mouse	LD50	oral	159mg/kg (159mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951.
mouse	LD50	subcutaneous	97mg/kg (97mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951.
rabbit	LD50	intravenous	100mg/kg (100mg/kg)		FAO Nutrition Meetings Report Series. Vol. 46A, Pg. 18, 1969.
rat	LD50	oral	161mg/kg (161mg/kg)		Reviews of Environmental Contamination and Toxicology. Vol. 113, Pg. 47, 1990.

Quercetin Safety Profile

Hazard Codes of Quercetin (CAS NO.117-39-5): Toxic T, Irritant Xi
Risk Statements: 25-36/37/38
R25: Toxic if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 45-36-26
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36: Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: 2811
RTECS: LK8750000
HazardClass: 6.1(b)
PackingGroup: III

Quercetin Specification

Drug interactions of Quercetin (CAS NO.117-39-5): It is contraindicated with some antibiotics; it may interact with fluoroquinolones (a type of medicinal antibiotic), as quercetin competitively binds to bacterial DNA gyrase. It is also a potent inhibitor of CYP3A4 and CYP2C9, which are enzymes that break down most drugs in the body.

Product Name

Quercetin

Synthetic route

Quercetin Chemical Properties

Quercetin Uses

Quercetin Toxicity Data With Reference

Quercetin Safety Profile

Quercetin Specification

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