Product Name

  • Name

    Sodium 2-biphenylate

  • EINECS 205-055-6
  • CAS No. 132-27-4
  • Density 1.213 g/cm3
  • Solubility 1220 g kg-1 (35 °C)
  • Melting Point 59 °C
  • Formula C12H9NaO
  • Boiling Point 282 °C at 760 mmHg
  • Molecular Weight 192.193
  • Flash Point 140.3 °C
  • Transport Information UN 3077 9/PG 3
  • Appearance light brown or beige solid
  • Safety 22-26-61
  • Risk Codes 22-37/38-41-50
  • Molecular Structure Molecular Structure of 132-27-4 (Sodium 2-biphenylate)
  • Hazard Symbols HarmfulXn, DangerousN
  • Synonyms 2-Biphenylol,sodium salt (8CI);Phenol, o-phenyl-, sodium deriv. (6CI);[1,1'-Biphenyl]-2-ol, sodium salt (9CI);2-Hydroxydiphenyl sodium;2-Phenylphenol sodium salt;Deccosol;Dowicide;Dowicide A;Microban P 2;Mystox WFA;Natriphene;Preventol ON extra;SOPP;2-Biphenylol sodium salt;Sodium 2-hydroxydiphenyl;Sodium 2-phenylphenate;Sodium 2-phenylphenoate;Sodium 2-phenylphenol;Sodium o-phenylphenate;Sodium o-phenylphenol;Sodiumo-phenylphenoxide;Stopmold B;o-Phenylphenol sodium salt;[1,1'-Biphenyl]-2-ol,sodium salt (1:1);
  • PSA 23.06000
  • LogP 3.49740

Synthetic route

2-Phenylphenol
90-43-7

2-Phenylphenol

sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

Conditions
ConditionsYield
With sodium; benzene
With ethanol; sodium
With sodium hydroxide at 60℃;
With sodium hydroxide at 80 - 100℃;
dichlorobis(acetylacetonato)vanadium(IV)

dichlorobis(acetylacetonato)vanadium(IV)

sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

VCl(acetylacetonate)2(2-phenylphenoxide)
1161750-07-7

VCl(acetylacetonate)2(2-phenylphenoxide)

Conditions
ConditionsYield
In tetrahydrofuran byproducts: NaCl; to Na-compd. in THF a suspension of V-compd. in THF added, molar ratio VCl2(acac)2:NaOAr 1:1, stirred for 3-4 h, refluxed for about 5 h; filtered, solv. removed in vac., treated repeatedly with Et2O and petroleum ether, dried in vac., recrystallized from THF, elem. anal.;99%
dichlorobis(acetylacetonato)vanadium(IV)

dichlorobis(acetylacetonato)vanadium(IV)

sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

V(acetylacetonate)2(2-phenylphenoxide)2
1161750-08-8

V(acetylacetonate)2(2-phenylphenoxide)2

Conditions
ConditionsYield
In tetrahydrofuran byproducts: NaCl; to Na-compd. in THF a suspension of V-compd. in THF added, molar ratio VCl2(acac)2:NaOAr 1:2, stirred for 3-4 h, refluxed for about 5 h; filtered, solv. removed in vac., treated repeatedly with Et2O and petroleum ether, dried in vac., recrystallized from THF, elem. anal.;99%
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

Carbonic acid methyl ester (R)-1-methyl-allyl ester

Carbonic acid methyl ester (R)-1-methyl-allyl ester

2-((R)-1-Methyl-allyloxy)-biphenyl

2-((R)-1-Methyl-allyloxy)-biphenyl

Conditions
ConditionsYield
With Wilkinson's catalyst; phosphorous acid trimethyl ester In tetrahydrofuran at 0 - 20℃; Etherification;96%
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

N,N-Dimethylthiocarbamoyl chloride
16420-13-6

N,N-Dimethylthiocarbamoyl chloride

O-([1,1'-biphenyl]-2-yl) N,N-dimethylcarbamothioate
10345-41-2

O-([1,1'-biphenyl]-2-yl) N,N-dimethylcarbamothioate

Conditions
ConditionsYield
In N,N-dimethyl-formamide 1.) r.t., 2.) 80 deg C, 45 min;86%
In N,N-dimethyl-formamide at 20 - 80℃; Alkylation;86%
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

cyclohexane-1,2-epoxide
286-20-4

cyclohexane-1,2-epoxide

(+/-)-trans-2-(2-phenylphenoxy)cyclohexan-1-ol

(+/-)-trans-2-(2-phenylphenoxy)cyclohexan-1-ol

Conditions
ConditionsYield
In water for 4h; Heating;62%
carbon dioxide
124-38-9

carbon dioxide

sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

3-phenylsalicylic acid
304-06-3

3-phenylsalicylic acid

Conditions
ConditionsYield
at 190℃; under 15200 Torr; for 24h;40%
cyclothiophosphazene
38595-77-6

cyclothiophosphazene

sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

1-(Biphenyl-2-yloxy)-3,3,5,5-tetrachloro-1λ4,3λ5,5λ5-[1,2,4,6,3,5]thiatriazadiphosphinine
144514-50-1

1-(Biphenyl-2-yloxy)-3,3,5,5-tetrachloro-1λ4,3λ5,5λ5-[1,2,4,6,3,5]thiatriazadiphosphinine

Conditions
ConditionsYield
In 1,4-dioxane at 15℃; for 2h;
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

aniline
62-53-3

aniline

2-hydroxy-5-(phenylazo)biphenyl
79380-82-8

2-hydroxy-5-(phenylazo)biphenyl

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite 1.) 0 deg C, 2.) 0-2 deg C; Yield given. Multistep reaction;
ethanol
64-17-5

ethanol

sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

sodium monochloroacetic acid
3926-62-3

sodium monochloroacetic acid

ethyl (<1,1'-biphenyl>-2-yloxy)acetate
107352-46-5

ethyl (<1,1'-biphenyl>-2-yloxy)acetate

Conditions
ConditionsYield
(i) H2O, (ii) /BRN= 1718733/, H2SO4; Multistep reaction;
...Expand
4-Bromodiphenyl ether
101-55-3

4-Bromodiphenyl ether

sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

1-(o-Phenyl-phenoxy)-4-phenoxy-benzol
3983-83-3

1-(o-Phenyl-phenoxy)-4-phenoxy-benzol

Conditions
ConditionsYield
With copper at 275 - 300℃;
2-benzoylbenzoyl chloride
22103-85-1

2-benzoylbenzoyl chloride

diethyl ether
60-29-7

diethyl ether

sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

benzene
71-43-2

benzene

A

2-benzoyl-benzoic acid biphenyl-2-yl ester

2-benzoyl-benzoic acid biphenyl-2-yl ester

B

3--3-phenyl-phthalide

3--3-phenyl-phthalide

...Expand
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

(hex-1-en-3-yl)methyl carbonate
83135-00-6

(hex-1-en-3-yl)methyl carbonate

A

2-(1-propyl-allyloxy)-biphenyl

2-(1-propyl-allyloxy)-biphenyl

B

2-[((E)-Hex-2-enyl)oxy]-biphenyl

2-[((E)-Hex-2-enyl)oxy]-biphenyl

Conditions
ConditionsYield
With Wilkinson's catalyst; phosphorous acid trimethyl ester In tetrahydrofuran at 0 - 20℃; Etherification; Title compound not separated from byproducts;
With Wilkinson's catalyst; phosphorous acid trimethyl ester In tetrahydrofuran at 0 - 20℃; Etherification; Title compound not separated from byproducts.;
...Expand
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

(2R*,3S*)-ethyl 3-chloro-2-morpholino-3-phenylpropionate

(2R*,3S*)-ethyl 3-chloro-2-morpholino-3-phenylpropionate

A

(2R,3R)-2-(Biphenyl-2-yloxy)-3-morpholin-4-yl-3-phenyl-propionic acid ethyl ester

(2R,3R)-2-(Biphenyl-2-yloxy)-3-morpholin-4-yl-3-phenyl-propionic acid ethyl ester

B

(2S,3S)-3-(Biphenyl-2-yloxy)-2-morpholin-4-yl-3-phenyl-propionic acid ethyl ester

(2S,3S)-3-(Biphenyl-2-yloxy)-2-morpholin-4-yl-3-phenyl-propionic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 60℃; for 12h; Substitution; Title compound not separated from byproducts.;
...Expand
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

Carbonic acid methyl ester (R)-1-methyl-allyl ester

Carbonic acid methyl ester (R)-1-methyl-allyl ester

A

2-((R)-1-Methyl-allyloxy)-biphenyl

2-((R)-1-Methyl-allyloxy)-biphenyl

B

2-((S)-1-Methyl-allyloxy)-biphenyl

2-((S)-1-Methyl-allyloxy)-biphenyl

Conditions
ConditionsYield
With Wilkinson's catalyst; phosphorous acid trimethyl ester In tetrahydrofuran at 0 - 20℃; Etherification;
...Expand
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

2-isopropoxybiphenyl-3-carbaldehyde
478942-83-5

2-isopropoxybiphenyl-3-carbaldehyde

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 40 percent / 24 h / 190 °C / 15200 Torr
2: 100 percent / K2CO3 / 12 h / 50 °C
3: LiAlH4 / tetrahydrofuran / Heating
4: MnO2 / diethyl ether / 12 h / 20 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

2-isopropoxy-3-vinyl-1,1'-biphenyl
478942-85-7

2-isopropoxy-3-vinyl-1,1'-biphenyl

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 40 percent / 24 h / 190 °C / 15200 Torr
2: 100 percent / K2CO3 / 12 h / 50 °C
3: LiAlH4 / tetrahydrofuran / Heating
4: MnO2 / diethyl ether / 12 h / 20 °C
5: tBuOK / diethyl ether / 0.17 h / 0 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

(2-isopropoxy-biphenyl-3-yl)-methanol
566162-85-4

(2-isopropoxy-biphenyl-3-yl)-methanol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 40 percent / 24 h / 190 °C / 15200 Torr
2: 100 percent / K2CO3 / 12 h / 50 °C
3: LiAlH4 / tetrahydrofuran / Heating
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

C16H15(2)HO2

C16H15(2)HO2

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 40 percent / 24 h / 190 °C / 15200 Torr
2: 100 percent / K2CO3 / 12 h / 50 °C
3: 94 percent / LiAlD4 / tetrahydrofuran / Heating
4: MnO2 / diethyl ether / 12 h / 20 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

C17H17(2)HO

C17H17(2)HO

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 40 percent / 24 h / 190 °C / 15200 Torr
2: 100 percent / K2CO3 / 12 h / 50 °C
3: 94 percent / LiAlD4 / tetrahydrofuran / Heating
4: MnO2 / diethyl ether / 12 h / 20 °C
5: tBuOK / diethyl ether / 0.17 h / 0 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

C16H16(2)H2O2
566162-88-7

C16H16(2)H2O2

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 40 percent / 24 h / 190 °C / 15200 Torr
2: 100 percent / K2CO3 / 12 h / 50 °C
3: 94 percent / LiAlD4 / tetrahydrofuran / Heating
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

2-isopropoxy-biphenyl-3-carboxylic acid isopropyl ester
566162-84-3

2-isopropoxy-biphenyl-3-carboxylic acid isopropyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 40 percent / 24 h / 190 °C / 15200 Torr
2: 100 percent / K2CO3 / 12 h / 50 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

[1,1′-biphenyl]-2-yl(methyl)sulfane
19813-75-3

[1,1′-biphenyl]-2-yl(methyl)sulfane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 92 percent / NaOH; H2O / 2.33 h / 110 °C
View Scheme
Multi-step reaction with 4 steps
1: 86 percent / dimethylformamide / 1.) r.t., 2.) 80 deg C, 45 min
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 92 percent / NaOH / H2O / 2.33 h / 110 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

2-phenylbenzenethiol
2688-96-2

2-phenylbenzenethiol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: 86 percent / dimethylformamide / 1.) r.t., 2.) 80 deg C, 45 min
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

S-<2-Diphenylyl>-dimethylthiocarbaminat
16241-17-1

S-<2-Diphenylyl>-dimethylthiocarbaminat

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
View Scheme
Multi-step reaction with 2 steps
1: 86 percent / dimethylformamide / 1.) r.t., 2.) 80 deg C, 45 min
2: 0.58 h / 264 - 282 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

2-<(trifluoromethyl)sulfinyl>biphenyl
129922-49-2

2-<(trifluoromethyl)sulfinyl>biphenyl

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: LiH / dimethylformamide / -60 °C
5: SbF3 / 2 h / 150 - 160 °C
6: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
View Scheme
Multi-step reaction with 5 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 76 percent / NaH / dimethylformamide / 3 h / 50 °C
5: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
View Scheme
Multi-step reaction with 7 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 92 percent / NaOH; H2O / 2.33 h / 110 °C
5: 82 percent / Cl2 / CCl4 / 20 °C / Irradiation
6: 86 percent / Et3N*3HF / 9 h / 180 °C
7: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

2-<(trifluoromethyl)thio>biphenyl
129922-51-6

2-<(trifluoromethyl)thio>biphenyl

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: LiH / dimethylformamide / -60 °C
5: SbF3 / 2 h / 150 - 160 °C
View Scheme
Multi-step reaction with 4 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 76 percent / NaH / dimethylformamide / 3 h / 50 °C
View Scheme
Multi-step reaction with 6 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 92 percent / NaOH; H2O / 2.33 h / 110 °C
5: 82 percent / Cl2 / CCl4 / 20 °C / Irradiation
6: 86 percent / Et3N*3HF / 9 h / 180 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

Umemoto's reagent
129946-88-9

Umemoto's reagent

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: LiH / dimethylformamide / -60 °C
5: SbF3 / 2 h / 150 - 160 °C
6: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
7: 79 percent / H2SO4*SO3 / CH2Cl2 / 1.5 h / 20 °C
8: 92 percent / acetonitrile / 1.5 h / 60 °C
View Scheme
Multi-step reaction with 7 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 76 percent / NaH / dimethylformamide / 3 h / 50 °C
5: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
6: 79 percent / H2SO4*SO3 / CH2Cl2 / 1.5 h / 20 °C
7: 92 percent / acetonitrile / 1.5 h / 60 °C
View Scheme
Multi-step reaction with 9 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 92 percent / NaOH; H2O / 2.33 h / 110 °C
5: 82 percent / Cl2 / CCl4 / 20 °C / Irradiation
6: 86 percent / Et3N*3HF / 9 h / 180 °C
7: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
8: 79 percent / H2SO4*SO3 / CH2Cl2 / 1.5 h / 20 °C
9: 92 percent / acetonitrile / 1.5 h / 60 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

5-(trifluoromethyl)-5H-dibenzo[b,d]thiophenium-3-sulfonate
160656-62-2

5-(trifluoromethyl)-5H-dibenzo[b,d]thiophenium-3-sulfonate

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: LiH / dimethylformamide / -60 °C
5: SbF3 / 2 h / 150 - 160 °C
6: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
7: 84 percent / H2SO4*SO3 / CH2Cl2 / 20 h / 0 - 42 °C
View Scheme
Multi-step reaction with 8 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: LiH / dimethylformamide / -60 °C
5: SbF3 / 2 h / 150 - 160 °C
6: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
7: 79 percent / H2SO4*SO3 / CH2Cl2 / 1.5 h / 20 °C
8: H2SO4*SO3 / CH2Cl2 / 17 h / 42 °C
View Scheme
Multi-step reaction with 6 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 76 percent / NaH / dimethylformamide / 3 h / 50 °C
5: 98 percent / H2O2; H2O / acetic acid / 3 h / 80 - 88 °C
6: 84 percent / H2SO4*SO3 / CH2Cl2 / 20 h / 0 - 42 °C
View Scheme
sodium 2-biphenylate
132-27-4

sodium 2-biphenylate

2-<(Trichloromethyl)thio>biphenyl
220156-12-7

2-<(Trichloromethyl)thio>biphenyl

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 86 percent / dimethylformamide / 20 - 80 °C
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 92 percent / NaOH; H2O / 2.33 h / 110 °C
5: 82 percent / Cl2 / CCl4 / 20 °C / Irradiation
View Scheme
Multi-step reaction with 5 steps
1: 86 percent / dimethylformamide / 1.) r.t., 2.) 80 deg C, 45 min
2: 0.58 h / 264 - 282 °C
3: NaOH / methanol / 12 h / Heating
4: 92 percent / NaOH / H2O / 2.33 h / 110 °C
5: 82 percent / Cl2 / CCl4 / 1.75 h / 0 °C / Irradiation
View Scheme

Sodium 2-biphenylate Chemical Properties


IUPAC Name: Sodium 2-phenylphenolate
Canonical SMILES: C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+]
InChI: InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1
InChIKey: KSQXVLVXUFHGJQ-UHFFFAOYSA-M
Molecular Weight: 192.18903 [g/mol]
Molecular Formula: C12H9NaO
H-Bond Donor: 0
H-Bond Acceptor: 1 
EINECS: 205-055-6 
Appearance: light brown or beige solid
Density: 1.213 g/cm3
Melting Point: 59 °C
Flash Point: 140.3 °C
Enthalpy of Vaporization: 54.18 kJ/mol
Boiling Point: 282 °C at 760 mmHg
Vapour Pressure: 0.00202 mmHg at 25 °C
Water Solubility: Soluble
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Classification Code of 2-Biphenylol sodium salt (CAS NO.132-27-4): Agricultural Chemical; Fungicide, bactericide, wood preservative; Mutation data; Reproductive Effect; Skin / Eye Irritant; Tumor data

Sodium 2-biphenylate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 500mg/kg (500mg/kg)   FAO Nutrition Meetings Report Series. Vol. 38A, Pg. 47, 1965.
mouse LD50 oral 683mg/kg (683mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH		 Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 30, Pg. 54, 1979.
rat LD50 oral 656mg/kg (656mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: RELAXATION (ISOLATED TISSUE)		 Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 30, Pg. 57, 1979.

Sodium 2-biphenylate Consensus Reports

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon. France.: ) (single copies can be ordered from WHO Publications centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 30 (1983),p. 329.(World Health Organization, Internation Agency for Research on Cancer,Lyon. France.: ) (single copies can be ordered from WHO Publications centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.

Sodium 2-biphenylate Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. A human skin irritant. A severe skin irritant to experimental animals. When heated to decomposition it emits toxic fumes of Na2O. 
Hazard Codes: HarmfulXn,DangerousN
Risk Statements: 22-37/38-41-50
 R22:Harmful if swallowed. 
R37/38:Irritating to respiratory system and skin. 
R41:Risk of serious damage to the eyes. 
R50:Very toxic to aquatic organisms.
Safety Statements: 22-26-61 
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: DV7750000
HazardClass: 8
PackingGroup of 2-Biphenylol sodium salt (CAS NO.132-27-4): III

Sodium 2-biphenylate Specification

  2-Biphenylol sodium salt (CAS NO.132-27-4), its Synonyms are (1,1'-Biphenyl)-2-ol, sodium salt ; Sodium o-phenylphenate ; o-Phenyl phenol sodium salt ; 2-Hydroxybiphenyl sodium salt ; 2-Hydroxydiphenyl sodium ; 2-Hydroxydiphenyl, sodium salt ; 2-Phenylphenol sodium salt ; Dowicide ; Dowicide A ; Dowicide A & A flakes ; Dowicide A Flakes ; Phenol, o-phenyl-, sodium deriv. ; Phenylphenol, sodium salt ; Preventol ON & ON Extra ; Preventol ON extra ; Preventol-ON ; Sodium (1,1'-biphenyl)-2-olate .

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