Sodium formate supplier | CasNO.141-53-7

Name
Sodium formate
EINECS 205-488-0
CAS No. 141-53-7
Article Data292
CAS DataBase
Density 1.16 g/mL at 20 °C
Solubility soluble in water
Melting Point 259-262 °C(lit.)
Formula CHNaO₂
Boiling Point 100.6 °C at 760 mmHg
Molecular Weight 68.0075
Flash Point 29.9 °C
Transport Information
Appearance white crystals
Safety 26-37/39-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Salachlor;Sodium formate, refined;Formic acid, sodium salt;Sodium Formate(reagent grade);Sodium formate 95% & 97%;sodium formate 95% & 92%;Sodium formate 95%;Sodium Formate 96%;Sodium Formate 90%-98%;Leather, industrial special sodium formate;sodium formate 93% 95% supply;
PSA 40.13000
LogP -0.99800

Synthetic route

: 50-00-0
formaldehyd

: 64-18-6
formic acid

: 75-07-0
acetaldehyde

A: 115-77-5
Pentaerythritol

B: 126-58-9
Dipentaerythritol

C: 141-53-7
sodium formate

Conditions

Conditions	Yield
Stage #1: formaldehyd; acetaldehyde With sodium hydroxide at 45 - 65℃; under 1500.15 Torr; for 1.38333h; Inert atmosphere; Stage #2: formic acid pH=6; Product distribution / selectivity;	A 87.4% B 5% C 99.7%

...Expand

: 124-38-9
carbon dioxide

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With sodium amalgam In not given Kinetics; High Pressure; in 1 M HCOONa-solution satd. with NaHCO3, CO2-pressure 15 kg/cm2 and at 0-55°C;	99%
With sodium amalgam In water circulating CO2 and react. soln. at ambient temp., normal or raised pressure, pH 4.4-5.0;;	91%
With sodium amalgam In not given Kinetics; in 1 M HCOONa-solution satd. with NaHCO3, CO2-pressure 1 kg/cm2 and at 0-55°C;	70%

: calcium carbonate

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With sodium nitrite In water at 90℃; under 760.051 Torr; for 6h; Reagent/catalyst; Concentration; Temperature;	98.98%

: 1310-73-2
sodium hydroxide

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With carbon monoxide In water heating NaOH soln. with pressure 20 atm;;	96.1%
With carbon monoxide In neat (no solvent) CO (6-7 atm.) is passed over finely powdered NaOH (eventually a mixture of NaOH and CaO) at 150-170°C;;	> 99
With carbon monoxide In water

: 1886-34-6
2-methyl-4-amino-5-formylaminomethylpyrimidine

A: 95-02-3
5-(aminomethyl)-2-methylpyrimidin-4-amine

B: 141-53-7
sodium formate

Conditions

Conditions	Yield
With sodium hydroxide; water In methanol at 66.84 - 75.84℃; for 4.5h; Product distribution / selectivity;	A 95.9% B 56.3%
With sodium hydroxide; water In 1,2-dimethoxyethane at 80℃; for 4h; Product distribution / selectivity;	A 94.2% B 91.9%
With sodium hydroxide; water In isopropyl alcohol at 80 - 85℃; for 3.5 - 5.5h; Product distribution / selectivity;	A 93.2% B 72.5%

: N-(3-methyl-4,6-diphenylpyridin-2-yl)formamide

A: 3-methyl-4,6-diphenylpyridin-2-amine

B: 141-53-7
sodium formate

Conditions

Conditions	Yield
With sodium hydroxide In dimethyl sulfoxide at 100℃; for 12h;	A 95% B 61%

: 144-62-7
oxalic acid

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With tetrasodium phenylporphyrintetrasulphonatoferrate(III); oxygen; sodium hydroxide In water at 150℃; under 15001.5 Torr; for 3h; Autoclave;	94.7%

: 60-12-8
2-phenylethanol

A: 3412-44-0
(1E)-1,3-diphenylpropene

B: 141-53-7
sodium formate

Conditions

Conditions	Yield
With (bis[(2-diisopropylphosphino)ethyl]amine)Mn(CO)2Br; sodium hydroxide In 5,5-dimethyl-1,3-cyclohexadiene at 145℃; for 16h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Schlenk technique; Inert atmosphere;	A 93% B n/a

: 124-38-9
carbon dioxide

: 1333-74-0
hydrogen

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With sodium hydroxide In dimethyl sulfoxide (Rh(cod)Cl)2 and phosphine ligand are dissolved in DMSO under N2 and Et3N is added, mixt. is stirred for 20 min and transferred to an autoclave, which is purged and pressurised with CO2 (20 atm) and then with H2 (40 atm), after 18 h aq. NaOH is added; filtn. (catalyst), water and Et3O are removed from the filtrate in vac., filtn., washing (Et2O); amt. of formic acid by NMR;	91%
With water; palladium In not given Electrolysis; high pressure;; poor yield;;
With H2O
With Mo(NO)(CO)(N(CH2CH2PiPr2)2); sodium hexamethyldisilazane In tetrahydrofuran at 140℃; under 75007.5 Torr; for 15h; Reagent/catalyst; Time; Inert atmosphere; Schlenk technique; Glovebox; Autoclave; High pressure;	4 %Spectr.

: 108-86-1
bromobenzene

: 201230-82-2
carbon monoxide

A: 532-32-1
sodium benzoate

B: 141-53-7
sodium formate

Conditions

Conditions	Yield
With sodium hydroxide; tetraethylammonium iodide; triphenylphosphine; bis(benzonitrile)palladium(II) dichloride In water; m-xylene at 85 - 90℃; for 14h; Product distribution; influence of various PTC; effect of molar ratio;	A 90% B 9.3%

...Expand

: 87375-49-3
1-chloroperfluoro-2-hexanone

A: 141-53-7
sodium formate

B: 2706-89-0
Sodium perfluoropentanoate

Conditions

Conditions	Yield
With sodium hydroxide In water Product distribution; Heating;	A n/a B 87%

: 144-55-8
sodium hydrogencarbonate

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With nickel; hydrogen In water at 200℃; under 45004.5 Torr; for 2h; Catalytic behavior; Reagent/catalyst; Temperature; Pressure; Green chemistry;	86.6%
With hydrogen In water at 100℃; under 30003 Torr; for 10h; Autoclave;	85.3%
With RuCl2((iPr2PCH2CH2)2NH); hydrogen In water at 150℃; under 25858.1 Torr; for 18h; Temperature;	84%

: sodium 4-toluenesulfinate

: 50-00-0
formaldehyd

: 64-18-6
formic acid

: 70-55-3
toluene-4-sulfonamide

A: 141-53-7
sodium formate

B: 41369-60-2
N-(p-toluenesulfonylmethyl)-p-toluenesulfonamide

Conditions

Conditions	Yield
In water at 70 - 75℃;	A n/a B 85%

...Expand

: 87375-48-2
1,1-dichloroperfluoro-2-butanone

A: 75-43-4
Dichlorofluoromethane

B: 141-53-7
sodium formate

C: 378-77-8
sodium pentafluoropropionate

Conditions

Conditions	Yield
With sodium hydroxide In water Product distribution;	A 33.5% B n/a C 84.5%

...Expand

: 87375-46-0
1-chloroheptafluoro-2-butanone

A: 141-53-7
sodium formate

B: 378-77-8
sodium pentafluoropropionate

Conditions

Conditions	Yield
With sodium hydroxide In water for 1h; Product distribution; Heating;	A n/a B 83%

: C15H13N6O7(1-)*Na(1+)

A: 141-53-7
sodium formate

B: N'-(5,7-dinitro-2,1,3-benzoxadiazol-4-yl)-N,N-dimethyl-1,4-diaminobenzene

Conditions

Conditions	Yield
With water at 90℃; for 1h;	A n/a B 75%

: 497-19-8
sodium carbonate

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With nickel; hydrogen In water at 200℃; under 45004.5 Torr; for 2h; Green chemistry;	71.2%
With sodium nitrite In water at 90℃; for 6h; Reagent/catalyst;	48.7%
With H2; catalyst: (RuCl2(benzene))2/dppm In tetrahydrofuran; water 50 bar H2 and 30 bar CO, 2 h at 70°C; detd. by NMR;
With (1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one) irontricarbonyl complex3; Cr(3+)HO(1-)C8H4O4(2-)*H2O; hydrogen In water; dimethyl sulfoxide at 100℃; under 37503.8 Torr; for 20h; Catalytic behavior; Reagent/catalyst; Autoclave; Inert atmosphere;

: 124-38-9
carbon dioxide

A: 141-53-7
sodium formate

B: 144-55-8
sodium hydrogencarbonate

Conditions

Conditions	Yield
With RuCl2((iPr2PCH2CH2)2NH); water; hydrogen; sodium hydroxide at 140℃; under 25858.1 Torr; for 4h; Temperature;	A 71% B 29%
With RuCl2((iPr2PCH2CH2)2NH); water; hydrogen; sodium hydroxide at 130℃; under 25858.1 Torr; for 4h;	A 29.5% B 70.5%

: 75-46-7
trifluoromethan

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With sodium hydroxide at 140℃; under 2585.81 Torr; for 24h; Solvent; Temperature;	65%

: 506-87-6
ammonium carbonate

: 141-53-7
sodium formate

Conditions

Conditions	Yield
With sodium tetrahydroborate; copper(II) oxide In water at 90℃; under 760.051 Torr; for 6h; Reagent/catalyst;	64.79%

Sodium formate Specification

The Sodium formate, with the CAS registry number 141-53-7,is also known as Thionyl dichloride. It belongs to the product categories of Salachlor; Formic acid sodium salt.This chemical's molecular formula is CHNaO₂ and molecular weight is 68.01. What's more,Its systematic name is Sodium formate.It is white crystals,which is stable,incompatible with strong oxidizing agents,strong acids,protect from moisture.Its storage temperature is 2-8°C.The Sodium formate is irritating to eyes, respiratory system and skin.When you use it ,wear suitable protective clothing, gloves and eye/face protection.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .

Physical properties about Sodium formate are:
(1)ACD/LogP: -0.54; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.30; (4)ACD/LogD (pH 7.4): -3.94; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 0; (12)Flash Point: 29.9 °C; (13)Enthalpy of Vaporization: 22.69 kJ/mol; (14)Boiling Point: 100.6 °C at 760 mmHg; (15)Vapour Pressure: 36.5 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES:[Na+].[O-]C=O;
(2)Std. InChI:InChI=1S/CH2O2.Na/c2-1-3;/h1H,(H,2,3);/q;+1/p-1;
(3)Std. InChIKey:HLBBKKJFGFRGMU-UHFFFAOYSA-M.

Production of Sodium formate:
Reacting chloroform with an alcoholic solution of sodium hydroxide produces sodium formate; neutralizeing formatic acid with sodium carbonate also produces Sodium formate. The formular is as following:
CHCl₃ + 4NaOH → HCOONa + 3NaCl + 2H₂O
by reacting sodium hydroxide with chloral hydrate:
2HCl₃(OH)₂ + NaOH → CHCl₃ + HCOONa + H₂O
The latter method is better than the former, since the low aqueous solubility of CHCl3 makes it easier to separate out from the sodium formate solution than the soluble NaCl would be by fractional crystallization.
The commercial way to produce sodium formate is to bsorbing carbon monoxide under pressure in solid sodium hydroxide at 160 °C, showing below:
CO + NaOH → HCOONa

The toxicity data of Sodium formate as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	subcutaneous	1140mg/kg (1140mg/kg)	BEHAVIORAL: SLEEP BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 21, Pg. 119, 1886.
dog	LDLo	intravenous	3gm/kg (3000mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 16, Pg. 463, 1921.
dog	LDLo	oral	4gm/kg (4000mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 16, Pg. 463, 1921.
mouse	LD50	intravenous	807mg/kg (807mg/kg)		Zeitschrift fuer Ernaehrungswissenschaft. Vol. 9, Pg. 332, 1969.
mouse	LD50	oral	11200mg/kg (11200mg/kg)		Zeitschrift fuer Ernaehrungswissenschaft. Vol. 9, Pg. 332, 1969.
mouse	LD50	unreported	2500mg/kg (2500mg/kg)		British Journal of Cancer. Vol. 6, Pg. 160, 1952.
rabbit	LDLo	intravenous	1250mg/kg (1250mg/kg)	KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 21, Pg. 119, 1886.

Product Name

Sodium formate

Synthetic route

Sodium formate Specification

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