Sodium propan-2-olate supplier

Name
Sodium propan-2-olate
EINECS 211-673-7
CAS No. 683-60-3
Article Data34
CAS DataBase
Density 0.9 g/cm³
Solubility
Melting Point 70-75 °C
Formula C₃H₇NaO
Boiling Point 73°C at 760 mmHg
Molecular Weight 82.0777
Flash Point -19°C
Transport Information
Appearance Yellow-brown crystals similar to alcohol
Safety 16-26-43-45
Risk Codes 11-34-41
Molecular Structure
Hazard Symbols C,F
Synonyms 2-Propanol,sodium salt (9CI);Isopropyl alcohol, sodium salt (8CI);Sodium isopropoxide(6CI,7CI);Isopropanol sodium salt;Isopropoxysodium;Sodium isopropanolate;Sodium isopropyl oxide;Sodium isopropylate;
PSA 23.06000
LogP 0.82530

Synthetic route

: 108-20-3
di-isopropyl ether

: 1822-71-5
n-pentylsodium

A: 683-60-3
sodium isopropylate

B: 2521-40-6
allyl sodium

Conditions

Conditions	Yield
With pentane

...Expand

: 108-20-3
di-isopropyl ether

: 1822-71-5
n-pentylsodium

: 109-66-0
pentane

A: 683-60-3
sodium isopropylate

B: 2521-40-6
allyl sodium

...Expand

: C9H10N3O5(1-)*Na(1+)

A: 683-60-3
sodium isopropylate

B: 18771-85-2
4-nitrobenzofuroxan

Conditions

Conditions	Yield
In isopropyl alcohol at 15 - 35℃; Kinetics;
In isopropyl alcohol at 25℃; Equilibrium constant; Thermodynamic data; ΔH(excit.), ΔS(excit.);

: C12H17N2O6(1-)*Na(1+)

A: 10242-16-7
2,4-dinitrophenyl isopropyl ether

B: 683-60-3
sodium isopropylate

Conditions

Conditions	Yield
In isopropyl alcohol at 25℃; Equilibrium constant;

: C12H16ClN2O6(1-)*Na(1+)

A: 71338-03-9
6-Chlor-1-isopropoxy-2,4-dinitrobenzol

B: 683-60-3
sodium isopropylate

Conditions

Conditions	Yield
In isopropyl alcohol at 25℃; Equilibrium constant;

: C16H23N2O8(1-)*Na(1+)

A: 71338-04-0
1-Isopropoxy-6-isopropoxycarbonyl-2,4-dinitrobenzol

B: 683-60-3
sodium isopropylate

Conditions

Conditions	Yield
In isopropyl alcohol at 25℃; Equilibrium constant;

: C12H16N3O8(1-)*Na(1+)

A: 10242-23-6
2,4,6-trinitrophenyl isopropyl ether

B: 683-60-3
sodium isopropylate

Conditions

Conditions	Yield
With sodium perchlorate In isopropyl alcohol at 25℃; Equilibrium constant;

: 67-63-0
isopropyl alcohol

: 683-60-3
sodium isopropylate

Conditions

Conditions	Yield
With sodium at 60 - 90℃; for 1h; Product distribution / selectivity;
With sodium hydride at 0℃;
With sodium hydride

: 2996-92-1
phenyl trimethylsiloxane

: 67-63-0
isopropyl alcohol

A: sodium-bond phenylsilsesquioxane

B: tetrasodium salt of double-decker phenylsilsesquioxane

C: 683-60-3
sodium isopropylate

Conditions

Conditions	Yield
With sodium hydroxide In water at 20℃; for 4.25h; Reflux; Overall yield = 22.15 g;

...Expand

: 683-60-3
sodium isopropylate

: 81171-31-5
[2-Chloro-1-methyl-2-phenyl-eth-(E)-ylidene]-isopropyl-amine

: 103818-65-1
isopropyl N-isopropyl-3-phenylpropanimidate

Conditions

Conditions	Yield
In isopropyl alcohol for 18h; Heating;	100%

: 683-60-3
sodium isopropylate

: 125335-77-5
2-Chloro-3-(4,4-dimethyl-2-oxazolinyl)pyridine

: 125335-80-0
3-(4,4-Dimethyl-2-oxazolinyl)-2-isopropyloxypyridine

Conditions

Conditions	Yield
In tetrahydrofuran; isopropyl alcohol for 5h; Heating;	100%

: 683-60-3
sodium isopropylate

: 2-(p-methoxyphenyl)-1,3-diphenylbenzothiophenium perchlorate

: C30H28O2S

Conditions

Conditions	Yield
In isopropyl alcohol for 12h; Heating;	100%

: 683-60-3
sodium isopropylate

: 4,5-diphenyl-1,2-thiazinylium perchlorate

: 400869-07-0
6-isopropyloxy-4,5-diphenyl-6H-1,2-thiazine

Conditions

Conditions	Yield
In isopropyl alcohol at 0℃;	100%

: 6818-44-6
methyl 3,7,12-triacetoxycholan-24-oate

: 683-60-3
sodium isopropylate

: 1428531-66-1
isopropyl 3α-hydroxy,7α,12α-diacetoxy-5β-cholan-24-oate

Conditions

Conditions	Yield
In isopropyl alcohol at 20℃; for 0.333333h;	100%
In isopropyl alcohol at 20℃; for 0.333333h;

: 3764-01-0
2,4,6-trichloropyrimidine

: 683-60-3
sodium isopropylate

: 2-chloro-4,6-diisopropoxypyrimidine

Conditions

Conditions	Yield
In isopropyl alcohol at 0 - 20℃;	100%

: 683-60-3
sodium isopropylate

: 3-tert-butyl-2-benzoselenopyrylium tetrafluoroborate

: 3-tert-butyl-1-isopropoxy-1H-isoselenochromene

Conditions

Conditions	Yield
In isopropyl alcohol at 20℃;	99%

: 76439-45-7
3-chloro-4-nitropyridine N-oxide

: 683-60-3
sodium isopropylate

: 3-chloro-4-isopropoxypyridine 1-oxide

Conditions

Conditions	Yield
With isopropyl alcohol at 20 - 30℃; for 1h;	98.8%

: 683-60-3
sodium isopropylate

: 187806-29-7
[6-Hydroxy-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)chroman-5-yl]methyl bromide

: 5a-isopropoxy-α-tocopherol

Conditions

Conditions	Yield
In ethanol; hexane; isopropyl alcohol at 0℃; for 1h;	98%

: 1224855-10-0
4-chloro-1,6-dimethyl-1H-pyrazolo[4,3-c]pyridin-3-amine

: 683-60-3
sodium isopropylate

: 67-63-0
isopropyl alcohol

: 1224855-15-5
4-isopropoxy-1,6-dimethyl-1H-pyrazolo[4,3-c]pyridin-3-amine

Conditions

Conditions	Yield
for 18h; Reflux;	98%

...Expand

: (S)-tert-butyl (4-(2-(3-cyano-4-fluorophenyl)thiazol-5-yl)-2,3-dihydro-1H-inden-1-yl)carbamate

: 683-60-3
sodium isopropylate

: (S)-tert-butyl (4-(2-(3-cyano-4-isopropoxyphenyl)thiazol-5-yl)-2,3-dihydro-1H-inden-1-yl)carbamate

Conditions

Conditions	Yield
In isopropyl alcohol at 60℃; for 4h;	98%

: 3206-44-8
5-methanesulfonyl-1-phenyl-1H-tetrazole

: 683-60-3
sodium isopropylate

: 5-(i-propoxy)-1-phenyltetrazole

Conditions

Conditions	Yield
	96%

: 36082-50-5
2,4-dichloro-5-bromopyrimidine

: 683-60-3
sodium isopropylate

: 5-bromo-2,4-diisopropoxypyrimidine

Conditions

Conditions	Yield
In tetrahydrofuran; isopropyl alcohol at -20℃; for 1h; Inert atmosphere;	96%
	75%

: 683-60-3
sodium isopropylate

: 3-tert-butyl-2-benzotelluropyrylium tetrafluoroborate

: 3-tert-butyl-1-isopropoxy-1H-isotellurochromene

Conditions

Conditions	Yield
In isopropyl alcohol at 20℃;	96%

: 683-60-3
sodium isopropylate

: 555-31-7
aluminum isopropoxide

: sodium tetra(iso-propoxo)aluminate

Conditions

Conditions	Yield
to a soln. of Al-compd. a soln. of Na-i-PrO is added, mixt. is refluxed for 12 h, then allowed to cool to room temp. (N2); ppt. is filtered off, the filtrate is evapd. under vac. and cooled to 0°C, from this viscous soln. crystals are grown, elem. anal.;	96%
In isopropyl alcohol crystn. on mixing Al- and Na- compd. solns., alcohol excess decantation off; elem. anal.; X-ray diffraction;

: trans-(Pt(CCPh)2(Ph2PCH2PPh2Me)2)I2

: 683-60-3
sodium isopropylate

: (C6H5CC)2Pt(P(C6H5)2CHP(CH3)(C6H5)2)2

Conditions

Conditions	Yield
In dichloromethane; isopropyl alcohol a suspension of Pt-complex in THF was treated with sodium propane-2-oxide in propan-2-ol, stirred for 5 min, a further portion of sodium propane-2-oxide was added, warmed, stood for 2 h; evapd., H2O was added, recrystd. from CH2Cl2-EtOH; elem. anal.;	96%

: 683-60-3
sodium isopropylate

: 644-97-3
Dichlorophenylphosphine

: 36238-99-0
di(isopropyl) phenylphosphonite

Conditions

Conditions	Yield
In 1,4-dioxane at 10 - 50℃; for 5h; Temperature; Solvent; Concentration; Inert atmosphere;	95.9%

: 683-60-3
sodium isopropylate

: 496840-11-0
2-bromo-6-(iodomethyl)pyridine

: 399031-17-5
2-bromo-6-(isopropoxymethyl)pyridine

Conditions

Conditions	Yield
In tetrahydrofuran at 0℃;	95%

: 683-60-3
sodium isopropylate

: 10213-09-9
vanadyl chloride

: 119254-23-8
vanadyl diisopropoxide

Conditions

Conditions	Yield
In ethanol byproducts: NaCl; vacuum., mixing of alcoholic VOCl2 and soln. of NaO(i-Pr) in EtOH, room temp.; removal of pptd. NaCl (freezing, liquid N2), evapn. (ca. 40°C); elem. anal.;	95%

: 683-60-3
sodium isopropylate

: 5588-84-1
vanadium(V) oxytriisopropoxide

: sodium tetraisopropylorthovanadate

Conditions

Conditions	Yield
In hexane; isopropyl alcohol; toluene To a soln. of (i-PrO)3VO in hexane a soln. of i-PrONa in a toluene/isopropyl alcohol mixt. was added under Ar.; Solvent was completely removed under vac., elem. anal.;	95%

: Ca(2+)*2Al(3+)*8H(1-)*4C4H8O=Ca(AlH4)2*4C4H8O

: 683-60-3
sodium isopropylate

: 555-31-7
aluminum isopropoxide

: Ca[AlH2(OCH(CH3)2)2]2(C4H8O)2

Conditions

Conditions	Yield
With calcium chloride In tetrahydrofuran byproducts: NaCl; under N2, soln. of Ca(AlH4)2 in THF added slowly to stirred suspn. of CaCl2, NaOC3H7 and Al(OC3H7)3 in THF, stirred and refluxed for 18 h; filtered, evapd. in vac., dried (2 h, room temp., 1E-2 Torr); elem. anal.;	95%

...Expand

: 66152-71-4
trans-(carbonyl)chlorobis[(phenylethynyl)di-t-butylphosphine]rhodium(I)

: 683-60-3
sodium isopropylate

: 66118-61-4
carbonyl[2-(di-t-butylphosphino)-1-phenylethyleneoxo-OP][(phenylethynyl)di-t-butylphosphine]rhodium(I)

Conditions

Conditions	Yield
In isopropyl alcohol refluxing Rh-complex with slight lack of i-PrONa (16 h); evapn., treatment of oil with H2O, filtration; elem. anal.;	95%

: 12082-05-2
(η6-fluorobenzene)tricarbonylchromium

: 683-60-3
sodium isopropylate

: 16049-60-8
isopropoxybenzene tricarbonyl chromium

Conditions

Conditions	Yield
In dimethyl sulfoxide	94.76%
In dimethyl sulfoxide	94.76%

: 683-60-3
sodium isopropylate

: 127505-62-8
2,6-diallyltetrahydropyran

: 112698-53-0
5-ethoxy-4-isopropyloxymethyl-exo-10-oxatricyclo<5.2.1.02,6>deca-4,8-dien-3-one

Conditions

Conditions	Yield
In isopropyl alcohol for 0.5h; Heating;	94%

: {(η4-C7H7-2-CH2OAc)RhCl}2

: 683-60-3
sodium isopropylate

: closo-3,3-(η2,η3-2-methylenenorbornadienyl)-1,2-(CH3)2-3,1,2-RhC2B9H9

Conditions

Conditions	Yield
With {nido-7,8-Me2C2B9H10}K In isopropyl alcohol under argon atmosphere, addn. of B-compd. to suspn. of i-PrONa (prepd. from dispersn. of NaH in nujol and i-PrOH), stirring (1 h, room temp.), addn. of Rh-compd., stirring (0.5 h), evapn. (vac.) addn. of acidified ether; sepn. of etheral layer, washing ether exts. with H2O, drying, evapn., chromy. (silica gel, ether), recrystn. (CH2Cl2/ether);	94%

: sodium aluminum tetrahydride

: 683-60-3
sodium isopropylate

: 555-31-7
aluminum isopropoxide

: Ca(2+)*2Al(3+)*4H(1-)*4(CH3)2CHO(1-)*C4H8O=Ca[AlH2(OCH(CH3)2)2]2*C4H8O

Conditions

Conditions	Yield
With tetrahydrofuran; calcium chloride In tetrahydrofuran; toluene byproducts: NaCl; under N2, soln. of Al(O-i-Pr)3 in toluene added slowly to stirred suspn. of NaAlH4, CaCl2 and NaO-i-Pr in toluene and THF, heated at 60°C and stirred for 5.5 h; filtered, evapd. in vac., dried (2 h, room temp., 1E-2 Torr); elem. anal.;	94%
With tetrahydrofuran; calcium chloride In tetrahydrofuran byproducts: NaCl; under N2, soln. of Al(O-i-Pr)3 in t-BuOMe added slowly to stirred suspn. of NaAlH4, CaCl2 and NaO-i-Pr in t-BuOMe and THF, heated at reflux andstirred for 4.5 h; filtered, evapd. in vac., dried (2 h, room temp., 1E-2 Torr); elem. anal.;	92%

...Expand

: 66152-69-0
trans-(carbonyl)chlorobis[(phenylethynyl)di-t-butylphosphine]iridium(I)

: 683-60-3
sodium isopropylate

: 66118-60-3
carbonyl[2-(di-t-butylphosphino)-1-phenylethyleneoxo-OP][(phenylethynyl)di-t-butylphosphine]iridium(I)

Conditions

Conditions	Yield
In isopropyl alcohol refluxing Ir-complex with slight lack of i-PrONa (16 h); evapn., treatment with H2O; elem. anal.;	94%

: 201230-82-2
carbon monoxide

: 1591-31-7
4-iodo-biphenyl

: 683-60-3
sodium isopropylate

: 916235-64-8
4-phenylbenzoic acid isopropyl ester

Conditions

Conditions	Yield
With bis-triphenylphosphine-palladium(II) chloride; isopropyl alcohol at 80℃; under 7600.51 Torr; for 24h; Autoclave;	94%

...Expand

: 4648-54-8
trimethylsilylazide

: 683-60-3
sodium isopropylate

: 104-88-1
4-chlorobenzaldehyde

: [(4-chlorophenyl)(isopropoxy)methoxy]trimethylsilane

Conditions

Conditions	Yield
In tetrahydrofuran; benzene at 20℃; for 1h;	94%

...Expand

: 683-60-3
sodium isopropylate

: 155262-17-2
2-fluoro-5-phenyl-3-trifluoromethylthiophene

: 2-(1-methylethoxy)-5-phenyl-3-trifluoromethylthiophene

Conditions

Conditions	Yield
In 1,4-dioxane for 1h;	93%

Sodium propan-2-olate Specification

The IUPAC name of Sodium isopropoxide is sodium propan-2-olate. With the CAS registry number 683-60-3, it is also named as 2-Propanol, sodium salt. It is yellow-brown crystals similar to alcohol which reacts strong with water. Additionally, this chemical can be obtained by the reaction of metallic sodium and dried isopropanol. It should be stored in a container which is filled dry inert gas. And the container is placed in the cool and dry aera. When heated to decomposition it emits toxic fumes of Na₂O.

The other characteristics of this product can be summarized as: (1)H-Bond Donor: 0; (2)H-Bond Acceptor: 1; (3)Rotatable Bond Count: 0; (4)Exact Mass: 82.03946; (5)MonoIsotopic Mass: 82.03946; (6)Topological Polar Surface Area: 23.1; (7)Heavy Atom Count: 5; (8)Complexity: 14.4; (9)Covalently-Bonded Unit Count: 2.

Uses of Sodium isopropoxide: It is used as Ibuprofen intermediate. And in many reactions such as polymerization of butadiene, it used as a catalyst. Additionally, Sodium isopropoxide is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

When you are using this chemical, please be cautious about it as the following:
It is highly flammable, so people should keep it away from sources of ignition. And it can cause burns and has risk of serious damage to the eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

People can use the following data to convert to the molecule structure.
1. SMILES:CC(C)O[Na]
2. InChI:InChI=1/C3H7O.Na/c1-3(2)4;/h3H,1-2H3;/q-1;+1/rC3H7NaO/c1-3(2)5-4/h3H,1-2H3

Product Name

Sodium propan-2-olate

Synthetic route

Sodium propan-2-olate Specification

Related Products

Hot Products