Sulfoacetic acid supplier | CasNO.123-43-3

Name
SULFOACETIC ACID
EINECS 204-627-2
CAS No. 123-43-3
Article Data79
CAS DataBase
Density 1.875g/cm³
Solubility 103.7g/L at 25℃
Melting Point 81-88 °C(lit.)
Formula C2H4 O5 S
Boiling Point °Cat760mmHg
Molecular Weight 140.117
Flash Point °C
Transport Information
Appearance
Safety Moderately toxic by ingestion and skin contact. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of SO_x.
Risk Codes 34-36/37
Molecular Structure
Hazard Symbols
Synonyms Aceticacid, sulfo- (6CI,7CI,8CI,9CI);Sulfoacetic acid;Sulfoethanoic acid;
PSA 100.05000
LogP 0.03960

Synthetic route

: 420-12-2
thirane

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With nitric acid bei der Oxydation;

: 60-35-5
acetamide

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With chlorosulfonic acid

: 56-23-5
tetrachloromethane

: 2308-54-5
acetoxysulfonic acid

: 123-43-3
sulfoacetic acid

: 69406-58-2
chloro-sulfo-acetic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With sodium amalgam

: 5138-18-1
sulfosuccinic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With potassium hydroxide

: 594-45-6
ethanesulfonic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With water at 75 - 80℃; bei der elektrolytischen Oxydation an Platin;
With sulfuric acid at 75 - 80℃; bei der elektrolytischen Oxydation an PbO2;

: 107-36-8
2-hydroxyethanesulfonic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With chromic acid

: 24523-90-8
(aminoiminomethyl)thioacetic acid ethyl ester

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With water; chlorine

: 505-73-7
disulfanediyldiacetic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With dihydrogen peroxide; iron(II) sulfate

: 2308-54-5
acetoxysulfonic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With tetrachloromethane

: 3926-62-3
sodium monochloroacetic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With sodium sulfite

: 108-24-7
acetic anhydride

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With sulfuric acid
With sulfuric acid
With sulfur trioxide; oxygen im UV-Licht;

: 5321-77-7
(formylmethyl)mercury chloride

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With sulfur trioxide; 1,2-dichloro-ethane

: 64-19-7
acetic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With sulfur trioxide
With chlorosulfonic acid at 140℃;

: 64-19-7
acetic acid

A: 123-43-3
sulfoacetic acid

B: 503-40-2
methanedisulfonic acid

Conditions

Conditions	Yield
With chlorosulfonic acid unter Kuehlung und Erhitzen des Reaktionsgemisches dann auf 140grad;

: 68-11-1
mercaptoacetic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With nitric acid

: 75-36-5
acetyl chloride

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With silver sulfate at 120℃;

: 79-11-8
chloroacetic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
With water; sodium carbonate; sodium sulfite isolierung aus Bariumsalz;

: 89124-45-8
acetic acid ethylester sulfonic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
saponification;

: 64-19-7
acetic acid

A: 123-43-3
sulfoacetic acid

B: 100151-21-1
Acetylsulfat

C: 2480-60-6
diacetyl sulfate

D: acetyl disulphate (keto-form)

Conditions

Conditions	Yield
With sulfur trioxide In liquid sulphur dioxide Product distribution; effect of temperature;

...Expand

: 7664-93-9
sulfuric acid

: 108-24-7
acetic anhydride

: 64-19-7
acetic acid

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
at 40℃; Rate constant;

...Expand

: 7647-01-0
hydrogenchloride

: 37704-67-9
2-ethylamino-thiazol-4-one

barium chlorate: barium chlorate

A: 625-52-5
N-Ethylurea

B: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
folgend Eindampfen der von Barium befreiten Loesung;

...Expand

: 108-24-7
acetic anhydride

oleum: oleum

A: 123-43-3
sulfoacetic acid

B: 503-40-2
methanedisulfonic acid

C: 54322-33-7
methanetrisulfonic acid

Conditions

Conditions	Yield
je nach den Bedingungen wechselnden Mengen;

...Expand

: 420-12-2
thirane

: 7697-37-2
nitric acid

A: 123-43-3
sulfoacetic acid

B 2-carboxymethylsulfanyl-ethane-sulfonic acid-(1): 2-carboxymethylsulfanyl-ethane-sulfonic acid-(1)

...Expand

: 7647-01-0
hydrogenchloride

: 7732-18-5
water

: 466-71-7
(16-hydroxy-3β-methoxy-erythrina-1,6-dien-15-yloxysulfonyl)-acetic acid

A: 123-43-3
sulfoacetic acid

B erysopine: erysopine

...Expand

: 7647-01-0
hydrogenchloride

: 7732-18-5
water

: 466-79-5
(3β,16-dimethoxy-erythrina-1,6-dien-15-yloxysulfonyl)-acetic acid

A: 123-43-3
sulfoacetic acid

B erysovine: erysovine

...Expand

: 7790-94-5
chlorosulfonic acid

: 64-19-7
acetic acid

: 123-43-3
sulfoacetic acid

: 7790-94-5
chlorosulfonic acid

: 75-36-5
acetyl chloride

: 123-43-3
sulfoacetic acid

Conditions

Conditions	Yield
at 60℃; unter Ausschluss von Luftfeuchtigkeit und Zersetzen des Reaktionsprodukts mit Eis; bei 4 stuendiger Einw.;

: 64-19-7
acetic acid

oleum: oleum

A: 123-43-3
sulfoacetic acid

B: 54322-33-7
methanetrisulfonic acid

Conditions

Conditions	Yield
at 95℃;

...Expand

: 7722-84-1
dihydrogen peroxide

: 68-11-1
mercaptoacetic acid

A: 123-43-3
sulfoacetic acid

B: 505-73-7
disulfanediyldiacetic acid

C: 7664-93-9
sulfuric acid

...Expand

: 64-17-5
ethanol

: 123-43-3
sulfoacetic acid

: 89124-45-8
acetic acid ethylester sulfonic acid

Conditions

Conditions	Yield
Heating;	100%

: 123-43-3
sulfoacetic acid

: 13194-73-5
3,5-dibromo-4-methylaniline

: C9H9Br2NO4S

Conditions

Conditions	Yield
With dmap; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h;	99%

: 123-43-3
sulfoacetic acid

: 1057671-89-2
C15H17NO

: 1160847-68-6
N-[3-(3-phenoxyphenyl)propyl](sulfo)acetamide

Conditions

Conditions	Yield
Stage #1: sulfoacetic acid; C15H17NO With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 2h; Stage #2: In methanol	85%

: 67-56-1
methanol

: 123-43-3
sulfoacetic acid

: 220457-32-9, 743422-30-2, 97775-27-4
5α,10β,15α,20β-tetrakis(2-aminophenyl)porphyrinatoiron(III) chloride

: 7732-18-5
water

: sodium 5α,10β,15α,20β-tetrakis(2-(sulfonatoacetamido)phenyl)porphyrinatoiron(III) hydroxide hexahydrate*3(methanol)

Conditions

Conditions	Yield
With isobutyl chlorocarbonate; triethyl amine In dichloromethane sulfoacetic acid added to soln. of isobutyl carbonate and Et3N; stirred at room temp. for 30 min; soln. of Fe compd. in CH2Cl2 added; stirred atroom temp. for 24 h; evapd. to dryness; dissolved in CHCl3; org. layer extd. (aq. NaOH); aq. layer washed (CHCl3); soln. evapd. to dryness; dissolved in EtOH; filtered; filtrate evapd.; purified by chromy. (Cosmosil 75C18-OPN, MeOH-H2O); evapd. to dryness;recrystd. (MeOH-ether); elem. anal.;	79%

Yield

With isobutyl chlorocarbonate; triethyl amine In dichloromethane sulfoacetic acid added to soln. of isobutyl carbonate and Et3N; stirred at room temp. for 30 min; soln. of Fe compd. in CH2Cl2 added; stirred atroom temp. for 24 h; evapd. to dryness; dissolved in CHCl3; org. layer extd. (aq. NaOH); aq. layer washed (CHCl3); soln. evapd. to dryness; dissolved in EtOH; filtered; filtrate evapd.; purified by chromy. (Cosmosil 75C18-OPN, MeOH-H2O); evapd. to dryness;recrystd. (MeOH-ether); elem. anal.;

79%

...Expand

: dinitrato(1,2-diaminoethane)platinum(II)

: 123-43-3
sulfoacetic acid

: di-μ-sulfoacetato-bis(1,2-diaminoethane)platinum(II) trihydrate

Conditions

Conditions	Yield
In water Passing a sol. of Pt-complex through a column of an anion-exchange resin (Diaion SA10AOH), passing of an addnl. amount of H2O through the column, addn. of sulfoacetic acid to the eluate.; Concg. filtn., elem. anal.;	68%

: 123-43-3
sulfoacetic acid

: (S)-N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide

: (S)-14-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2,13-dioxo-6,9-dioxa-3,12-diazatetradecane-1-sulfonic acid

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; ((3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) In N,N-dimethyl-formamide at 20℃; for 16h;	62%

: 123-43-3
sulfoacetic acid

: C20H39NO4

: C22H40NO8S(1-)*Na(1+)

Conditions

Conditions	Yield
Stage #1: C20H39NO4 With triethylamine In tetrahydrofuran Stage #2: sulfoacetic acid With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride In chloroform for 18h; Cooling; Stage #3: With sodium hydrogencarbonate In chloroform	27.1%

: 123-43-3
sulfoacetic acid

: C22H43NO4

: C24H44NO8S(1-)*Na(1+)

Conditions

Conditions	Yield
Stage #1: C22H43NO4 With triethylamine In tetrahydrofuran Stage #2: sulfoacetic acid With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride In chloroform for 18h; Cooling; Stage #3: With sodium hydrogencarbonate In chloroform	27.1%

: 123-43-3
sulfoacetic acid

: C24H47NO4

: C26H48NO8S(1-)*Na(1+)

Conditions

Conditions	Yield
Stage #1: C24H47NO4 With triethylamine In tetrahydrofuran Stage #2: sulfoacetic acid With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride In chloroform for 18h; Cooling; Stage #3: With sodium hydrogencarbonate In chloroform	27.1%

: 87664-82-2
1,2,3,4-Tetrahydro-5,6-dimethoxy-2-methylisochinolin

: 123-43-3
sulfoacetic acid

: 87664-92-4
8-Acetyl-1,2,3,4-tetrahydro-5,6-dimethoxy-2-methylisochinolin

Conditions

Conditions	Yield
	24%

: 123-43-3
sulfoacetic acid

: 87664-46-8
1,2-Dimethoxy-5,7,8,9,9a,10-hexahydro-pyrrolo<1,2-b>isochinolin

: 87664-49-1
4-Acety-1,2-dimethoxy-5,7,8,9,9a,10-hexahydro-pyrrolo<1,2-b>isochinolin

Conditions

Conditions	Yield
for 0.0833333h; Heating;	23%

: 123-43-3
sulfoacetic acid

: (E)-N-(4-(1-(3-((2-(2-(2-aminoethoxy)ethoxy)acetamido)methyl)benzoyl)piperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide bis-2,2,2-trifluoroacetate

: (E)-3,12-dioxo-1-(3-(4-(4-(3-(pyridin-3-yl)acrylamido)butyl)piperidine-1-carbonyl)phenyl)-5,8-dioxa-2,11-diazatridecane-13-sulfonic acid 2,2,2-trifluoroacetate

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; ((3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) In N,N-dimethyl-formamide at 20℃; for 16h;	20.2%

: 123-43-3
sulfoacetic acid

: N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-2-((3-(2-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)propyl)thio)acetamide bis-2,2,2-trifluoroacetate

: C25H43N3O9S2*C2HF3O2

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 16h;	17.2%

: 123-43-3
sulfoacetic acid

: 4-(3-(4-(2-(2-(2-aminoethoxy)ethoxy)acetyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one 2,2,2-trifluoroacetate

: 2-((2-(2-(2-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-2-oxoethoxy)ethoxy)ethyl)amino)-2-oxoethane-1-sulfonic acid

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 16h;	7.9%

: 123-43-3
sulfoacetic acid

: (S)-N-(2-(2-aminoethoxy)ethyl)-5-(3-chloro-2-methyl-N-(1-(3-(3-methylpyridin-4-yl)phenyl)ethyl)phenylsulfonamido)pentanamide hydrochloric acid

: (S)-15-((3-chloro-2-methylphenyl)sulfonyl)-16-(3-(3-methylpyridin-4-yl)phenyl)-2,10- dioxo-6-oxa-3,9,15-triazaheptadecane-1-sulfonic acid

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;	6%

: 60-35-5
acetamide

: 123-43-3
sulfoacetic acid

: 503-40-2
methanedisulfonic acid

Conditions

Conditions	Yield
With sulfuric acid

: 67-56-1
methanol

: 123-43-3
sulfoacetic acid

: 63409-57-4
methoxycarbonyl-methanesulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; benzene durch anschliessende azeotrope Destillation;

: 112-92-5
1-octadecanol

: 123-43-3
sulfoacetic acid

: octadecyloxycarbonyl-methanesulfonic acid

Conditions

Conditions	Yield
at 100℃; unter vermindertem Druck;
at 100℃; unter vermindertem Druck;

Sulfoacetic acid Chemical Properties

Molecular Structure of Sulfoacetic acid (CAS NO.123-43-3):

EINECS: 204-627-2
IUPAC Name: 2-Sulfoacetic acid
Molecular Formula: C₂H₄O₅S
Molecular Weight: 140.115160 g/mol
XLogP3-AA: -1.3
H-Bond Donor: 2
H-Bond Acceptor: 5
Canonical SMILES: C(C(=O)O)S(=O)(=O)O
InChI: InChI=1S/C2H4O5S/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H,5,6,7)
InChIKey: AGGIJOLULBJGTQ-UHFFFAOYSA-N
Index of Refraction: 1.536
Molar Refractivity: 23.3 cm³
Molar Volume: 74.7 cm³
Surface Tension: 95.2 dyne/cm
Density: 1.875 g/cm³
Melting Point: 81-88 °C(lit.)
Water Solubility: 1.037e+005 mg/L at 25 °C
BRN: 1764390

Sulfoacetic acid Toxicity Data With Reference

1.	skn-rbt 20 mg/24H MOD	85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,1051.
2.	eye-rbt 250 µg/24H SEV	85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,1051.
3.	orl-rat LD50:3160 mg/kg	JIHTAB Journal of Industrial Hygiene and Toxicology. 31 (1949),60.
4.	skn-rbt LD50:1570 mg/kg	JIHTAB Journal of Industrial Hygiene and Toxicology. 31 (1949),60.

Sulfoacetic acid Consensus Reports

Reported in EPA TSCA Inventory.

Sulfoacetic acid Safety Profile

Safety Information of Sulfoacetic acid (CAS NO.123-43-3):
Hazard Codes: C Corrosive
Risk Statements: 34-36/37
R34:Causes burns
R36/37:Irritating to eyes and respiratory system
Safety Statements: 26-27-28-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S27:Take off immediately all contaminated clothing
S28:After contact with skin, wash immediately with plenty of soap-suds
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
RTECS: AJ4900000
HazardClass: 8
PackingGroup: III
Moderately toxic by ingestion and skin contact. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of SO_x.

Sulfoacetic acid Specification

Sulfoacetic acid with CAS registry number of 123-43-3 is also known as 4-04-00-00102 (Beilstein Handbook Reference) ; AI3-28536 ; Acetic acid, sulfo- ; Acetic acid, 2-sulfo- ; HSDB 2706 ; Kyselina sulfooctova ; Kyselina sulfooctova [Czech] ; Sulfoethanoic acid ; Sulphoacetic acid .

Product Name

SULFOACETIC ACID

Synthetic route

Sulfoacetic acid Chemical Properties

Sulfoacetic acid Toxicity Data With Reference

Sulfoacetic acid Consensus Reports

Sulfoacetic acid Safety Profile

Sulfoacetic acid Specification

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