Testosterone phenylpropionate supplier

Name
Testosterone phenylpropionate
EINECS 215-014-4
CAS No. 1255-49-8
Article Data9
CAS DataBase
Density 1.13 g/cm³
Solubility 2.25mg/L(25 oC)
Melting Point 116.5 °C
Formula C₂₈H₃₆O₃
Boiling Point 546.9 °C at 760 mmHg
Molecular Weight 420.592
Flash Point 233.3 °C
Transport Information
Appearance White crystalline powder
Safety 22-36
Risk Codes 20/21/22-40
Molecular Structure
Hazard Symbols Xn
Synonyms Testosterone,hydrocinnamate (6CI,7CI,8CI);Hydrocinnamic acid, ester with testosterone(8CI);3-Oxoandrost-4-en-17b-yl b-phenylpropionate;Hydrocinnamic acid, testosterone ester;NSC 26643;Retandrol;Testosterone17-phenylpropionate;
PSA 43.37000
LogP 6.06290

Synthetic route

: 103-25-3
3-phenylpropanoic acid methyl ester

: 58-22-0
testosterone

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
With Zn4(OCOCF3)6O In di-isopropyl ether for 40h; Heating;	96%

: 58-22-0
testosterone

: 104-55-2
3-phenyl-propenal

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
With 3-butyl-1-methylimidazolium acetate In 1,4-dioxane at 120℃; for 2h;	64%

: 131447-69-3
testosterone triphenylphosphoranylideneacetate

: 100-51-6
benzyl alcohol

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
With potassium tert-butylate; C16H35BrMnN3O2P2 In 1,4-dioxane at 130℃; for 24h; Inert atmosphere;	62.8%

: 58-22-0
testosterone

: 15781-96-1
3-phenylpropionic anhydride

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
With pyridine at 20℃;
at 100℃;
With pyridine at 20℃;
at 100℃;

: 58-22-0
testosterone

: 645-45-4
hydrocinnamic acid chloride

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
With pyridine
With pyridine; benzene
With pyridine
With pyridine; benzene

: 58-22-0
testosterone

: 501-52-0
3-Phenylpropionic acid

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
With carbon dioxide at 220℃;

: 52129-14-3
3-Phenyl-propionic acid (3S,8R,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
With cyclohexanone; aluminum isopropoxide In toluene

: 52129-09-6
3-Phenyl-propionic acid (3S,8R,9S,10R,13S,14S,17S)-3-acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: KOH / methanol; CH2Cl2 2: Al(OiPr)3, cyclohexanone / toluene View Scheme

: 1639-43-6
androstenediol-3-acetate

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: (i) PhSO2Cl, Py, (ii) /BRN= 2510253/ 2: KOH / methanol; CH2Cl2 3: Al(OiPr)3, cyclohexanone / toluene View Scheme

: 501-52-0
3-Phenylpropionic acid

cell culture of Dioscoreophyllum cumminsii: cell culture of Dioscoreophyllum cumminsii

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: (i) PhSO2Cl, Py, (ii) /BRN= 2510253/ 2: KOH / methanol; CH2Cl2 3: Al(OiPr)3, cyclohexanone / toluene View Scheme

: 58-22-0
testosterone

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: N,N-dimethyl-aniline / 1,4-dioxane / 3 h / 0 °C 2: benzene / 24 h 3: sodium hydroxide / water; methanol / 3 h 4: potassium tert-butylate; C16H35BrMnN3O2P2 / 1,4-dioxane / 24 h / 130 °C / Inert atmosphere View Scheme

: 4588-81-2
17β-bromoacetoxy-4-androsten-3-one

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: benzene / 24 h 2: sodium hydroxide / water; methanol / 3 h 3: potassium tert-butylate; C16H35BrMnN3O2P2 / 1,4-dioxane / 24 h / 130 °C / Inert atmosphere View Scheme

: ((8R,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yloxycarbonylmethyl)-triphenyl-phosphonium; bromide

: 1255-49-8
testosterone 17β-phenylpropionate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium hydroxide / water; methanol / 3 h 2: potassium tert-butylate; C16H35BrMnN3O2P2 / 1,4-dioxane / 24 h / 130 °C / Inert atmosphere View Scheme

: 123-51-3
i-Amyl alcohol

: 1255-49-8
testosterone 17β-phenylpropionate

: 120024-15-9
3-isopentyloxy-17β-(3-phenyl-propionyloxy)-androsta-3,5-diene

Conditions

Conditions	Yield
With 2,2,4-trimethylpentane; toluene-4-sulfonic acid

: 1255-49-8
testosterone 17β-phenylpropionate

: 100-53-8
phenylmethanethiol

: 120614-49-5
3-benzylsulfanyl-17β-(3-phenyl-propionyloxy)-androsta-3,5-diene

Conditions

Conditions	Yield
With 2,2,4-trimethylpentane; toluene-4-sulfonic acid

: 1255-49-8
testosterone 17β-phenylpropionate

: 1255-48-7
3-Chlor-17β-<3-phenyl-propionyloxy>-androsta-3,5-dien

Conditions

Conditions	Yield
With acetyl chloride; trichlorophosphate

: 356-42-3
2,2,3,3,3-pentafluoropropanoic anhydride

: 1255-49-8
testosterone 17β-phenylpropionate

: 2,2,3,3,3-Pentafluoro-propionic acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-17-(3-phenyl-propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Conditions

Conditions	Yield
at 70℃; for 0.25h;

: 1255-49-8
testosterone 17β-phenylpropionate

: 24589-78-4
N-methyl-N-trimethylsilyl-2,2,2-trifluoroacetamide

: 3-Phenyl-propionic acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-trimethylsilanyloxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl ester

Conditions

Conditions	Yield
With ammonium iodide; 1,4-dithio-erythritol at 60℃; for 0.25h;

: 1255-49-8
testosterone 17β-phenylpropionate

: 407-25-0
trifluoroacetic anhydride

: 3-Phenyl-propionic acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-(2,2,2-trifluoro-acetoxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl ester

Conditions

Conditions	Yield
at 70℃; for 0.25h;

: 1255-49-8
testosterone 17β-phenylpropionate

: 336-59-4
heptafluorobutyric anhydride

: 2,2,3,3,4,4,4-Heptafluoro-butyric acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-17-(3-phenyl-propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Conditions

Conditions	Yield
at 70℃; for 0.25h;

Testosterone phenylpropionate Specification

The Testosterone 17-phenylpropionate is steroid with the formula C₂₈H₃₆O₃. The IUPAC name of this chemical is [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] 3-phenylpropanoate. With the CAS registry number 1255-49-8, it is also named as 17beta-Hydroxyandrost-4-en-3-one 3-phenylpropionate. The classification codes are Hormone and Reproductive Effect. Additionally, it is white crystalline powder which is used as pharmaceutical raw material and intermediate. Furthermore, this chemical is male hormone.

The other characteristics of Testosterone 17-phenylpropionate can be summarized as: (1)ACD/LogP: 6.45; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 6.45; (4)ACD/LogD (pH 7.4): 6.45; (5)#H bond acceptors: 3; (6)#H bond donors: 0; (7)#Freely Rotating Bonds: 5; (8)Index of Refraction: 1.573; (9)Molar Refractivity: 122.04 cm³; (10)Molar Volume: 369.9 cm³; (11)Polarizability: 48.38×10^-24 cm³; (12)Surface Tension: 46.5 dyne/cm; (13)Enthalpy of Vaporization: 82.61 kJ/mol; (14)Vapour Pressure: 5.16E-12 mmHg at 25°C; (15)Rotatable Bond Count: 5; (16)Tautomer Count: 5; (17)Exact Mass: 420.266445; (18)MonoIsotopic Mass: 420.266445; (19)Topological Polar Surface Area: 43.4; (20)Heavy Atom Count: 31; (21)Complexity: 747.

When you are using this chemical, please be cautious about it as the following:
It is harmful by inhalation, in contact with skin and if swallowed, so people should not breathe dust. And it has limited evidence of a carcinogenic effect. If you want to contact this product, you must wear suitable protective clothing.

People can use the following data to convert to the molecule structure.
1. SMILES:O=C5\C=C3/[C@]([C@H]2CC[C@@]4([C@@H](OC(=O)CCc1ccccc1)CC[C@H]4[C@@H]2CC3)C)(C)CC5
2. InChI:InChI=1/C28H36O3/c1-27-16-14-21(29)18-20(27)9-10-22-23-11-12-25(28(23,2)17-15-24(22)27)31-26(30)13-8-19-6-4-3-5-7-19/h3-7,18,22-25H,8-17H2,1-2H3/t22-,23-,24-,25-,27-,28-/m0/s1

Product Name

Testosterone phenylpropionate

Synthetic route

Testosterone phenylpropionate Specification

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