Product Name

  • Name

    Thiabendazole

  • EINECS 205-725-8
  • CAS No. 148-79-8
  • Article Data50
  • CAS DataBase
  • Density 1.406 g/cm3
  • Solubility 0.005 g/100 mL in water
  • Melting Point 298-301 °C
  • Formula C10H7N3S
  • Boiling Point 446 °C at 760 mmHg
  • Molecular Weight 201.252
  • Flash Point 226.2 °C
  • Transport Information UN 3077 9/PG 3
  • Appearance light yellow powder
  • Safety 60-61-36-26
  • Risk Codes 50/53-36/37/38
  • Molecular Structure Molecular Structure of 148-79-8 (Thiabendazole)
  • Hazard Symbols IrritantXi,DangerousN
  • Synonyms Thibenzole 200;Mertect 160;MK 360;Tiabenda;Benzimidazole, 2- (4-thiazolyl)-;E-Z-Ex;4-(2-benzimidazolyl)thiazole;Polival;Hokustar HP;2-(4-Thiazolyl)-1H-benzimidazole;2-(4-Thiazolyl)benzimidazole;Bovizole;TectiviridaeTectivirusTecto;Pitrizet;Syntol M 100;MK-360;
  • PSA 69.81000
  • LogP 2.68640

Synthetic route

C10H9N3S*ClH

C10H9N3S*ClH

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With sodium hypochlorite; sodium carbonate In methanol; water at 0 - 65℃; for 1.5h; pH=9 - 10;97.82%
Stage #1: C10H9N3S*ClH With sodium carbonate In methanol; water at 0 - 5℃; for 0.333333h;
Stage #2: With sodium hypochlorite In methanol; water at 5 - 65℃; for 2h;
thiazole-4-carbonitrile
1452-15-9

thiazole-4-carbonitrile

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

ascorbic acid
50-81-7

ascorbic acid

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With hydrogenchloride; ethylenediaminetetraacetic acid In water92.7%
...Expand
thiazole-4-carbonitrile
1452-15-9

thiazole-4-carbonitrile

o-phenylenediamine hydrochloride
39145-59-0

o-phenylenediamine hydrochloride

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

ascorbic acid
50-81-7

ascorbic acid

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With hydrogenchloride; ethylenediaminetetraacetic acid In methanol; water91.7%
With hydrogenchloride; ethylenediaminetetraacetic acid In water
...Expand
Thiazole-4-carboxylic acid
3973-08-8

Thiazole-4-carboxylic acid

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
Stage #1: 1,2-diamino-benzene With polyphosphoric acid at 150℃; Inert atmosphere;
Stage #2: Thiazole-4-carboxylic acid at 230℃; for 2h; Reagent/catalyst; Temperature; Inert atmosphere;		88%
With polyphosphoric acid for 3h; Reflux;
thiazole-4-carbonitrile
1452-15-9

thiazole-4-carbonitrile

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

ascorbic acid
50-81-7

ascorbic acid

butan-1-ol
71-36-3

butan-1-ol

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With methanesulfonic acid In water87.1%
With acetic acid In water75.4%
...Expand
1,3-thiazole-4-carbaldehyde
3364-80-5

1,3-thiazole-4-carbaldehyde

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With sodium metabisulfite In N,N-dimethyl-formamide at 120℃;85%
Stage #1: 1,3-thiazole-4-carbaldehyde; 1,2-diamino-benzene In N,N-dimethyl-formamide for 0.0833333h; Inert atmosphere;
Stage #2: With sodium metabisulfite In N,N-dimethyl-formamide at 20℃; Inert atmosphere;
With sodium disulfite In N,N-dimethyl-formamide at 20℃; for 8h;
With sodium metabisulfite In N,N-dimethyl-formamide at 120℃;
With sodium metabisulfite In N,N-dimethyl-formamide for 6h;
thiazole-4-carbonitrile
1452-15-9

thiazole-4-carbonitrile

aminosulfonic acid
5329-14-6

aminosulfonic acid

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

ascorbic acid
50-81-7

ascorbic acid

butan-1-ol
71-36-3

butan-1-ol

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
In water75.7%
...Expand
thiazole-4-carbonitrile
1452-15-9

thiazole-4-carbonitrile

tin(II)chloride dihydrate

tin(II)chloride dihydrate

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

ascorbic acid
50-81-7

ascorbic acid

butan-1-ol
71-36-3

butan-1-ol

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
In water74.5%
...Expand
(E)-N-phenyl-N′-((4-(trifluoromethyl)benzoyl)oxy)thiazole-4-carboximidamide

(E)-N-phenyl-N′-((4-(trifluoromethyl)benzoyl)oxy)thiazole-4-carboximidamide

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate In tert-butyl methyl ether at 20℃; for 36h; Schlenk technique; Sealed tube; Inert atmosphere;40%
C18H12F3N3O2S

C18H12F3N3O2S

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate In tert-butyl methyl ether at 20℃; for 36h; Schlenk technique; Sealed tube;40%
MIDA (1H-benzo[d]imidazol-2-yl)boronate

MIDA (1H-benzo[d]imidazol-2-yl)boronate

4-bromo-1,3-thiazole
34259-99-9

4-bromo-1,3-thiazole

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); copper diacetate; potassium carbonate In tert-Amyl alcohol; N,N-dimethyl-formamide at 100℃; for 16h; Inert atmosphere;15%
thiazole-4-carbonitrile
1452-15-9

thiazole-4-carbonitrile

1-butanol+water

1-butanol+water

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
In water
diisopropyl malonate
13195-64-7

diisopropyl malonate

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

1,2-dihydroisoquinoline
2859-58-7

1,2-dihydroisoquinoline

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
In dichloromethane; ethyl acetate
...Expand
thiocarboxamide
115-08-2

thiocarboxamide

2-dibromoacetylbenzimidazole hydrobromide salt

2-dibromoacetylbenzimidazole hydrobromide salt

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With tetraphosphorus decasulfide In ethyl acetate at 45℃; for 2h;
1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrogenchloride / water / 3 h / 100 °C
2: sulfuric acid; potassium permanganate / acetone / 1.5 h / 35 - 40 °C
3: bromine; acetic acid / 1 h / 90 °C
4: tetraphosphorus decasulfide / ethyl acetate / 2 h / 45 °C
View Scheme
Multi-step reaction with 4 steps
1: hydrogenchloride / water / 0.03 h
2: sulfuric acid; potassium permanganate / acetone
3: acetic acid; bromine
4: tetraphosphorus decasulfide / ethyl acetate / 0.03 h
View Scheme
Multi-step reaction with 4 steps
1: hydrogenchloride / water
2: sulfuric acid; potassium permanganate / acetone
3: bromine; acetic acid
4: tetraphosphorus decasulfide / ethyl acetate
View Scheme
1-benzimidazol-2-ylethanol
16414-04-3, 19018-24-7

1-benzimidazol-2-ylethanol

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sulfuric acid; potassium permanganate / acetone / 1.5 h / 35 - 40 °C
2: bromine; acetic acid / 1 h / 90 °C
3: tetraphosphorus decasulfide / ethyl acetate / 2 h / 45 °C
View Scheme
Multi-step reaction with 3 steps
1: sulfuric acid; potassium permanganate / acetone
2: acetic acid; bromine
3: tetraphosphorus decasulfide / ethyl acetate / 0.03 h
View Scheme
Multi-step reaction with 3 steps
1: sulfuric acid; potassium permanganate / acetone
2: bromine; acetic acid
3: tetraphosphorus decasulfide / ethyl acetate
View Scheme
aniline
62-53-3

aniline

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogenchloride / 1,2-dichloro-benzene / 3 h / 135 °C
2.1: sodium carbonate / water; methanol / 0.33 h / 0 - 5 °C
2.2: 2 h / 5 - 65 °C
View Scheme
C10H9N3OS

C10H9N3OS

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 1 h / 0 °C
2: [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate / tert-butyl methyl ether / 36 h / 20 °C / Schlenk technique; Sealed tube; Inert atmosphere
View Scheme
2-dibromoacetylbenzimidazole hydrobromide salt

2-dibromoacetylbenzimidazole hydrobromide salt

formamide
77287-34-4, 77287-35-5, 60100-09-6

formamide

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
With tetraphosphorus decasulfide In ethyl acetate for 0.0333333h;
With tetraphosphorus decasulfide In ethyl acetate
MIDA ((2-((tert-butoxycarbonyl)amino)phenyl)carbamoyl)boronate

MIDA ((2-((tert-butoxycarbonyl)amino)phenyl)carbamoyl)boronate

thiabendazole
148-79-8

thiabendazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: trifluoroacetic acid / dichloromethane
2: chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); copper diacetate; potassium carbonate / N,N-dimethyl-formamide; tert-Amyl alcohol / 16 h / 100 °C / Inert atmosphere
View Scheme
thiabendazole
148-79-8

thiabendazole

copper dichloride

copper dichloride

(2-(4'-thiazolyl)benzimidazole)-dichloro-copper(II)
16091-87-5

(2-(4'-thiazolyl)benzimidazole)-dichloro-copper(II)

Conditions
ConditionsYield
In ethanol mixing of solns. (molar ratio metal:ligand 1:1), boiling (1-3 h); filtration, washing (EtOH), drying (air); elem. anal.;98%
thiabendazole
148-79-8

thiabendazole

mercury dichloride

mercury dichloride

[(2-(4'-thiazolyl)benzimidazole)]mercury dichloride

[(2-(4'-thiazolyl)benzimidazole)]mercury dichloride

Conditions
ConditionsYield
In ethanol molar ratio Hg : ligand = 1 : 1, stirring, boiling (1 h, pptn.); filtration off, washing (EtOH), drying (in air); elem. anal.;98%
thiabendazole
148-79-8

thiabendazole

benzoyl halide

benzoyl halide

1-benzoyl-2-thiazol-4-yl-1H-benzoimidazole
3916-49-2

1-benzoyl-2-thiazol-4-yl-1H-benzoimidazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol96%
2-Fluoro-5-nitropyridine
456-24-6

2-Fluoro-5-nitropyridine

thiabendazole
148-79-8

thiabendazole

4-(1-(5-nitropyridin-2-yl )-1H-benzo[d]imidazol-2-yl)thiazole

4-(1-(5-nitropyridin-2-yl )-1H-benzo[d]imidazol-2-yl)thiazole

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 23℃; for 12h; Inert atmosphere;95%
thiabendazole
148-79-8

thiabendazole

isopropyl halide

isopropyl halide

1-isopropyl-2-thiazol-4-yl-1H-benzoimidazole

1-isopropyl-2-thiazol-4-yl-1H-benzoimidazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol94%
thiabendazole
148-79-8

thiabendazole

phenyl-acetyl halide

phenyl-acetyl halide

2-phenyl-1-(2-thiazol-4-yl-benzoimidazol-1-yl)-ethanone

2-phenyl-1-(2-thiazol-4-yl-benzoimidazol-1-yl)-ethanone

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol94%
thiabendazole
148-79-8

thiabendazole

manganese(ll) chloride

manganese(ll) chloride

(2-(4'-thiazolyl)benzimidazole)-dichloro-manganese(II)
102412-37-3

(2-(4'-thiazolyl)benzimidazole)-dichloro-manganese(II)

Conditions
ConditionsYield
In ethanol mixing of solns. (molar ratio metal:ligand 1:1), boiling (1-3 h); filtration, washing (EtOH), drying (air); elem. anal.;94%
benzyl bromide
100-39-0

benzyl bromide

thiabendazole
148-79-8

thiabendazole

4-(1-benzyl-1H-benzo[d]imidazol-2-yl)thiazole
33705-43-0

4-(1-benzyl-1H-benzo[d]imidazol-2-yl)thiazole

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; Inert atmosphere;94%
With sodium hydride In N,N-dimethyl-formamide at 20℃;87%
Stage #1: thiabendazole With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h; Schlenk technique; Inert atmosphere;
Stage #2: benzyl bromide In N,N-dimethyl-formamide at 20℃; for 4h; Schlenk technique; Inert atmosphere;		65%
bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]
12354-84-6, 12354-85-7

bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]

thiabendazole
148-79-8

thiabendazole

[(η5‑C5Me5)IrCl(κ2‑N,N‑thiabendazole)]Cl

[(η5‑C5Me5)IrCl(κ2‑N,N‑thiabendazole)]Cl

Conditions
ConditionsYield
In dichloromethane at 20℃; for 20h; Inert atmosphere; Schlenk technique;94%
thiabendazole
148-79-8

thiabendazole

allyl halide

allyl halide

1-allyl-2-thiazol-4-yl-1H-benzoimidazole

1-allyl-2-thiazol-4-yl-1H-benzoimidazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol93%
thiabendazole
148-79-8

thiabendazole

butyl halide

butyl halide

1-butyl-2-thiazol-4-yl-1H-benzoimidazole

1-butyl-2-thiazol-4-yl-1H-benzoimidazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol93%
thiabendazole
148-79-8

thiabendazole

zinc(II) chloride
7646-85-7

zinc(II) chloride

(2-(4'-thiazolyl)benzimidazole)-dichloro-zinc
16091-86-4

(2-(4'-thiazolyl)benzimidazole)-dichloro-zinc

Conditions
ConditionsYield
In ethanol mixing of solns. (molar ratio metal:ligand 1:1), boiling (1-3 h); filtration, washing (EtOH), drying (air); elem. anal.;93%
thiabendazole
148-79-8

thiabendazole

cinnamyl halide

cinnamyl halide

(E)-3-Phenyl-1-(2-thiazol-4-yl-benzoimidazol-1-yl)-propenone

(E)-3-Phenyl-1-(2-thiazol-4-yl-benzoimidazol-1-yl)-propenone

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol92%
thiabendazole
148-79-8

thiabendazole

ethyl halide

ethyl halide

4-(1-ethyl-1H-benzo[d]imidazol-2-yl)thiazole

4-(1-ethyl-1H-benzo[d]imidazol-2-yl)thiazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol92%
thiabendazole
148-79-8

thiabendazole

propyl halide

propyl halide

N-propyl-2-(4-thiazolyl)benzimidazole
118625-65-3

N-propyl-2-(4-thiazolyl)benzimidazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol92%
thiabendazole
148-79-8

thiabendazole

benzyl halide

benzyl halide

4-(1-benzyl-1H-benzo[d]imidazol-2-yl)thiazole
33705-43-0

4-(1-benzyl-1H-benzo[d]imidazol-2-yl)thiazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol91%
With sodium hydride In N,N-dimethyl-formamide at 20℃;
sodium docusate
577-11-7

sodium docusate

thiabendazole
148-79-8

thiabendazole

thiabendazolium docusate
1337932-57-6

thiabendazolium docusate

Conditions
ConditionsYield
Stage #1: thiabendazole With hydrogenchloride In water at 20℃; for 1h;
Stage #2: sodium docusate In water; acetone at 20℃; Product distribution / selectivity;		91%
thiabendazole
148-79-8

thiabendazole

methyl iodide
74-88-4

methyl iodide

4-(1-methyl-1H-benzo[d]imidazol-2-yl)thiazole
32594-70-0

4-(1-methyl-1H-benzo[d]imidazol-2-yl)thiazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃;90%
Stage #1: thiabendazole With sodium hydride In N,N-dimethyl-formamide; benzene for 0.5h;
Stage #2: methyl iodide In N,N-dimethyl-formamide; benzene for 1h; Heating;		79%
Stage #1: thiabendazole With caesium carbonate In dimethyl sulfoxide at 80℃; for 1.5h; Inert atmosphere; Schlenk technique;
Stage #2: methyl iodide In dimethyl sulfoxide at 20℃; for 20h; Inert atmosphere; Schlenk technique;		71%
With sodium hydride; N,N-dimethyl-formamide In benzene Heating;
With sodium hydride In N,N-dimethyl-formamide
thiabendazole
148-79-8

thiabendazole

acetyl halide

acetyl halide

1-Acetyl-2-<4>thiazolyl-benzimidazole
3916-51-6

1-Acetyl-2-<4>thiazolyl-benzimidazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol90%
thiabendazole
148-79-8

thiabendazole

carboxymethyl halide

carboxymethyl halide

(2-Thiazol-4-yl-benzoimidazol-1-yl)-acetic acid

(2-Thiazol-4-yl-benzoimidazol-1-yl)-acetic acid

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol90%
thiabendazole
148-79-8

thiabendazole

methyl halide

methyl halide

4-(1-methyl-1H-benzo[d]imidazol-2-yl)thiazole
32594-70-0

4-(1-methyl-1H-benzo[d]imidazol-2-yl)thiazole

Conditions
ConditionsYield
With Amberlite IRA-400 (Cl(1-)form) resin In methanol90%
With sodium hydride In N,N-dimethyl-formamide at 20℃;
thiabendazole
148-79-8

thiabendazole

nickel dichloride

nickel dichloride

(2-(4'-thiazolyl)benzimidazole)2Cl2 nickel(II)

(2-(4'-thiazolyl)benzimidazole)2Cl2 nickel(II)

Conditions
ConditionsYield
In ethanol mixing of solns. (molar ratio metal:ligand 1:2), boiling (1-3 h); filtration, washing (EtOH), drying (air); elem. anal.;90%
nickel(II) nitrate hexahydrate

nickel(II) nitrate hexahydrate

thiabendazole
148-79-8

thiabendazole

[Ni(2-(4'-thiazolyl)benzimidazole)3]Cl2*3.5H2O

[Ni(2-(4'-thiazolyl)benzimidazole)3]Cl2*3.5H2O

Conditions
ConditionsYield
In ethanol addn. of a soln. of metal salt in ethanol to a soln. of ligand in ethanol, standing for 1 wk; elem. anal.;89%
aqueous cadmium chloride

aqueous cadmium chloride

diphenic acid
863305-32-2

diphenic acid

water
7732-18-5

water

thiabendazole
148-79-8

thiabendazole

Cd2(dpa)2(btz)2(H2O)2
1585253-38-8

Cd2(dpa)2(btz)2(H2O)2

Conditions
ConditionsYield
Stage #1: aqueous cadmium chloride; diphenic acid; water; thiabendazole With sodium hydroxide In methanol; N,N-dimethyl-formamide for 0.5h; pH=6;
Stage #2: In methanol; N,N-dimethyl-formamide at 130℃; for 72h; Sealed tube;		88%
...Expand
N-(4-nitrophenyl)bromoacetamide
3598-91-2

N-(4-nitrophenyl)bromoacetamide

thiabendazole
148-79-8

thiabendazole

N-(4-nitrophenyl)-2-(2-(thiazol-4-yl)-1H-benzo[d]imidazol-1-yl)acetamide

N-(4-nitrophenyl)-2-(2-(thiazol-4-yl)-1H-benzo[d]imidazol-1-yl)acetamide

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 8h;88%
thiabendazole
148-79-8

thiabendazole

1-bromomethyl-3-nitrobenzene
3958-57-4

1-bromomethyl-3-nitrobenzene

4-(1-(3-nitrobenzyl)-1H-benzo[d]imidazol-2-yl)thiazole

4-(1-(3-nitrobenzyl)-1H-benzo[d]imidazol-2-yl)thiazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃;88%

Thiabendazole Consensus Reports

EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

Thiabendazole Specification

Thiabendazole, with the IUPAC Name of 4-(1H-Benzimidazol-2-yl)-1,3-thiazole, is one kind of light yellow powder. This chemical belongs to the Product Categories which include Xanthones; Heterocyclic Compounds; FUNGICIDE; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur & Selenium Compounds; API's. With the CAS NO. 148-79-8, Thiabendazole is a systemic benzimidazole fungicide.

Physical properties about Thiabendazole are: (1)ACD/LogP: 2.47; (2)ACD/LogD (pH 5.5): 2.46; (3)ACD/LogD (pH 7.4): 2.47; (4)ACD/BCF (pH 5.5): 43.36; (5)ACD/BCF (pH 7.4): 44.36; (6)ACD/KOC (pH 5.5): 513.56; (7)ACD/KOC (pH 7.4): 525.39; (8)#H bond acceptors: 3; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 1; (11)Index of Refraction: 1.74; (12)Molar Refractivity: 57.687 cm3; (13)Molar Volume: 143.083 cm3; (14)Polarizability: 22.869 10-24cm3; (15)Surface Tension: 71.1259994506836 dyne/cm; (16)Density: 1.407 g/cm3; (17)Flash Point: 226.212 °C ; (18)Enthalpy of Vaporization: 70.403 kJ/mol; (19)Boiling Point: 445.951 °C at 760 mmHg

Uses of Thiabendazole: Thiabendazole is used primarily to control mold, blight, and other fungally caused diseases in fruits (e.g. oranges) and vegetables; it is also used as a prophylactic treatment for Dutch Elm disease and used in treatment of Aspergillus has been reported.As an antiparasitic, it is able to control roundworms, hookworms, and other helminth species which attack wild animals, livestock and humans.Medicinally, Thiabendazole is also a chelating agent, which means that it is used medicinally to bind metals in cases of metal poisoning, such as lead poisoning, mercury poisoning or antimony poisoning. In dogs and cats thiabendazole is also used to treat ear infections. Thiabendazole is also used as a food additive, a preservative with E number E233. For example, it is applied to bananas to ensure freshness, and is a common ingredient in the waxes applied to the skin of citrus fruits.

When you are using this chemical, please be cautious about it as the following:
1. This material and/or its container must be disposed of as hazardous waste;
2. Avoid release to the environment. Refer to special instructions safety data sheet;
3. Wear suitable protective clothing;
4. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;

You can still convert the following datas into molecular structure:
(1)InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13);
(2)InChIKey=WJCNZQLZVWNLKY-UHFFFAOYSA-N;
(3)Smilesc1(c2cscn2)[nH]c2ccccc2n1;

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 oral 4gm/kg (4000mg/kg)   Veterinarno-Meditsinski Nauki. Veterinary Science. Vol. 19(3), Pg. 99, 1982.
domestic animals - goat/sheep LD50 oral 400mg/kg (400mg/kg)   Veterinarno-Meditsinski Nauki. Veterinary Science. Vol. 19(3), Pg. 99, 1982.
man TDLo oral 47619ug/kg/1D (47.619mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pediatrics. Vol. 102, Pg. 317, 1983.
 
mouse LD50 oral 1300mg/kg (1300mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 55(10), Pg. 28, 1990.
rabbit LD50 oral 3850mg/kg (3850mg/kg)   "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.
rat LD50 oral 2080mg/kg (2080mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA		 Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.

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