• Name

  sulfiram

• EINECS
• CAS No. 95-05-6
• Article Data14
• CAS DataBase
• Density 1.139g/cm³
• Solubility
• Melting Point 30-32°
• Formula C10H20 N2 S3
• Boiling Point 329.1°Cat760mmHg
• Molecular Weight 264.48
• Flash Point 152.8°C
• Transport Information
• Appearance
• Safety

  RIDADR	2811
  HazardClass	6.1(b)
  PackingGroup	III

• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms Sulfide,bis(diethylthiocarbamoyl) (6CI,7CI,8CI); Thiodicarbonic diamide([(H2N)C(S)]2S), tetraethyl- (9CI); Thiuram monosulfide, tetraethyl- (4CI);Bis(N,N-diethylthiocarbamoyl) sulfide; Bis(diethylthiocarbamoyl) sulfide;Bis(diethylthiocarbamyl) sulfide; Carbamodithioic acid, diethyl-,anhydrosulfide; Kutka; Kutkasin; Methanethioamide, 1,1'-thiobis[N,N-diethyl-;Monosulfiram; NSC 36731; Sanigal; Sarcocide B; Sulfide,bis[(diethylamino)thioxomethyl]; Sulfiram; Sulfirame; Sulfiramum; TTMS; Tetmos;Tetmosol; Tetraethylthiuram monosulfide; Tetrucid
• PSA 95.96000
• LogP 2.97300

Synthetic route

88-11-9

N,N-diethylthiocarbamoyl chloride

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
With pyridine; hexamethyldisilathiane Heating;	66%

2391-78-8

N,N-diethyldithiocarbamate triethylamine salt

88-11-9

N,N-diethylthiocarbamoyl chloride

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 12h;	62%

463-71-8

thiophosgene

148-18-5

sodium N,N-diethyldithiocarbamate

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
With diethyl ether

148-18-5

sodium N,N-diethyldithiocarbamate

88-11-9

N,N-diethylthiocarbamoyl chloride

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
With water

148-18-5

sodium N,N-diethyldithiocarbamate

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
With sulfuric acid; dihydrogen peroxide; cyanide(1-)

97-77-8

disulfiram

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
With potassium cyanide In ethanol

75-44-5

phosgene

sodium diethyl dithiocarbamate

sodium diethyl dithiocarbamate

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
With water beim Erwaermen des Reaktionsprodukts mit Wasser auf 50grad;

{Sb(S2CN(C2H5)2)2}2CH2

A

methylene-bis-(antimony(III)-sulfide)

B

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
In neat (no solvent) decomposition on heating;;

121-44-8

triethylamine

95-05-6

tetraethylthiuram monosulfide

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: acetonitrile / 16 h / 20 °C 2: acetonitrile / 12 h / 20 °C View Scheme

95-05-6

tetraethylthiuram monosulfide

5416-93-3

4-Methoxyphenyl isocyanate

1,1,5,5-tetraethyl-3-(4-methoxy-phenyl)-dithiobiuret

95-05-6

tetraethylthiuram monosulfide

21198-48-1

4,4-diethyl-thiosemicarbazide

Conditions

Conditions	Yield
With hydrazine hydrate In ethanol Heating;

95-05-6

tetraethylthiuram monosulfide

7787-70-4

copper(I) bromide

A

168563-02-8

[CuBr((C2H5)2NC(S)SC(S)N(C2H5)2)]

B

copper diethyldithiocarbamate

Conditions

Conditions	Yield
In acetonitrile addn. of the monosulfide in MeCN with stirring to an ice-cooled soln. ofCuBr in MeCN; layering with Et2O, standing (freezer, 3 h), filtration, addn. of more Et2O, standing (freezer, overnight), decantation, washing (Et2O), drying in air; elem. anal.;

...Expand

7681-65-4

copper(l) iodide

95-05-6

tetraethylthiuram monosulfide

A

205104-84-3

[Cu5I5((C2H5)2NC(S)SC(S)N(C2H5)2)2]*C2H5OH*CH3CN

B

copper diethyldithiocarbamate

Conditions

Conditions	Yield
In acetonitrile addn. of the monosulfide in MeCN with stirring to an ice-cooled soln. ofCuI in MeCN; layering with Et2O, standing (freezer, 3 h), filtration, addn. of more Et2O, standing (freezer, overnight), decantation, washing (Et2O), drying in air;

...Expand

95-05-6

tetraethylthiuram monosulfide

copper(l) chloride

A

171624-55-8

[CuCl((C2H5)2NC(S)SC(S)N(C2H5)2)]

B

copper diethyldithiocarbamate

Conditions

Conditions	Yield
In acetonitrile addn. of the monosulfide in MeCN with stirring to an ice-cooled soln. ofCuCl in MeCN; layering with Et2O, standing (freezer, 3 h), filtration, addn. of more Et2O, standing (freezer, overnight), decantation, washing (Et2O), drying in air; elem. anal.;

...Expand

7681-65-4

copper(l) iodide

95-05-6

tetraethylthiuram monosulfide

A

203629-42-9

Cu5(tetraethylthiuram monosulfide)2I5

B

copper diethyldithiocarbamate

Conditions

Conditions	Yield
In acetonitrile addn. of 1 equiv. ligand to CuI (ice bath, stirring); layering with Et2O, fractional crystn. (freezer, overnight), collection (decantation), washing (ether), drying in air;

...Expand

95-05-6

tetraethylthiuram monosulfide

7789-45-9

copper(ll) bromide

168563-02-8

Cu(1+)*(CH3CH2)2NCS3CN(CH2CH3)2*Br(1-)

Conditions

Conditions	Yield
In ethanol (N2); stirring (-10°C); washing (EtOH), extracting (CH3CN), evapn., cooling (-10°C); elem. anal.;

95-05-6

tetraethylthiuram monosulfide

7789-45-9

copper(ll) bromide

(CH3CH2)2NCS3CN(CH2CH3)2(2+)*Cu(1+)*3Br(1-)=[(CH3CH2)2NCS3CN(CH2CH3)2]CuBr3

Conditions

Conditions	Yield
In ethanol (N2); stirring (-10°C); washing (EtOH), extracting (CH3CN), evapn.; elem. anal.;