-
Name
2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide monohydrochloride
- EINECS 213-836-8
- CAS No. 1027-14-1
- Article Data2
- CAS DataBase
- Density
- Solubility
- Melting Point 137-138℃ (acetone )
- Formula C15H24 N2 O . Cl H
- Boiling Point 360.3 °C at 760 mmHg
- Molecular Weight 284.829
- Flash Point 171.7 °C
- Transport Information
- Appearance
- Safety Poison by intraperitoneal and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Acetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, monohydrochloride (9CI);Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-, monohydrochloride (8CI);Acetanilide, 2-diethylamino-2',4',6'-trimethyl-, hydrochloride (6CI); Mesocain;Mesocaine; Trimecaine hydrochloride; Trimekain hydrochloride
- PSA 35.83000
- LogP 4.34360
Trimecaine Monohydrochloride Chemical Properties
Empirical Formula: C15H25ClN2O
Molecular Weight: 284.8248 g/mol
EINECS: 213-836-8
Flash Point: 171.7 °C
Enthalpy of Vaporization: 60.6 kJ/mol
Boiling Point: 360.3 °C at 760 mmHg
Vapour Pressure: 2.24E-05 mmHg at 25 °C
Structure of Trimecaine Monohydrochloride (CAS NO.1027-14-1):
IUPAC Name of Trimecaine Monohydrochloride (CAS NO.1027-14-1): Diethyl-[2-oxo-2-(2,4,6-trimethylanilino)ethyl]azanium chloride
Product Categories of Trimecaine Monohydrochloride (CAS NO.1027-14-1): Drug / Therapeutic Agent
Trimecaine Monohydrochloride Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 172mg/kg (172mg/kg) | Acta Facultatis Pharmaceuticae, Universitatis Comenianae. Vol. 29, Pg. 81, 1976. | |
| mouse | LD50 | intravenous | 50mg/kg (50mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Farmakologiya i Toksikologiya Vol. 25, Pg. 731, 1962. |
| mouse | LD50 | subcutaneous | 295mg/kg (295mg/kg) | "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 1526, 1989. | |
| rabbit | LD50 | intraperitoneal | 95mg/kg (95mg/kg) | Drug Metabolism and Drug Interactions. Vol. 9, Pg. 321, 1991. |
Trimecaine Monohydrochloride Safety Profile
Poison by intraperitoneal and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Trimecaine Monohydrochloride Specification
Trimecaine Monohydrochloride ,its cas register number is 1027-14-1. It also can be called Mesocaine ; Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-, hydrochloride ; and 2-(Diethylamino)-N-(2,4,6-trimethylphenyl)acetamide monohydrochloride .
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