Trimethylhydroquinone supplier

Name
Trimethylhydroquinone
EINECS 211-838-3
CAS No. 700-13-0
Article Data95
CAS DataBase
Density 1.126 g/cm³
Solubility 2 g/L (20 ºC)
Melting Point 169-174 °C
Formula C₉H₁₂O₂
Boiling Point 298.3 °C at 760 mmHg
Molecular Weight 152.193
Flash Point 146.3 °C
Transport Information UN 3077 9/PG 3
Appearance off-white, tan or orange powder
Safety 24-26-37/39-60-61
Risk Codes 20-37/38-41-43-50/53
Molecular Structure
Hazard Symbols Xn; N
Synonyms Hydroquinone,trimethyl- (6CI,7CI,8CI);1,4-Dihydroxy-2,3,5-trimethylbenzene;2,3,5-Trimethyl-1,4-benzenediol;2,3,5-Trimethyl-1,4-hydroquinone;2,3,5-Trimethyl-p-hydroquinone;2,3,5-Trimethylhydroquinone;NSC 401617;Pseudocumohydroquinone;Trimethyl-p-hydroquinone;Trimethylhydroquinone;y-Cumohydroquinone;
PSA 40.46000
LogP 2.02300

Synthetic route

: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
With sodium dithionite In diethyl ether; water	100%
With sodium dithionite In diethyl ether; water at 20℃;	100%
With hydrogen In isopropyl alcohol at 110℃; under 7500.75 Torr; Reagent/catalyst; Autoclave;	98%

: 79-21-0
peracetic acid

: 2416-94-6
2,3,6-trimethylphenol

A: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

B: 527-17-3, 70128-24-4
Duroquinone

C: 700-13-0
Trimethylhydroquinone

D: 2819-86-5
pentamethylphenol

E: 21573-36-4
1-methoxy-2,3,6-trimethylbenzene

F: 62687-45-0
2,3,6-trimethylphenyl acetate

Conditions

Conditions	Yield
sulfuric acid at 50℃; for 0.5h; Mechanism; Thermodynamic data; effect of catalysts;	A 99.7% B 0.04% C 0.01% D 0.01% E 0.03% F 0.04%

...Expand

: 7210-68-6
2-Bromo-3,5,6-trimethyl-1,4-benzoquinone

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
With hydrogen; sodium carbonate at 80℃;	94.7%

: 20547-99-3
2,6,6-trimethyl-1,4-cyclohexanedione

: 108-24-7
acetic anhydride

A: 700-13-0
Trimethylhydroquinone

B: 3938-10-1
trimethylpyrocatechol

Conditions

Conditions	Yield
Stage #1: 2,6,6-trimethyl-1,4-cyclohexanedione; acetic anhydride With sulfuric acid; acetic acid at 50℃; for 2h; Stage #2: With water for 3h; Heating / reflux;	A 88.5% B n/a

...Expand

: 95-63-6
1,2,4-Trimethylbenzene

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
Stage #1: 1,2,4-Trimethylbenzene With formic acid; dihydrogen peroxide; calcium chloride at 50 - 90℃; for 5h; Stage #2: With sodium dithionite In water at 45℃; for 2h; Temperature; Reagent/catalyst;	85.6%
With peracetic acid; sodium disulfite 1) acetic acid, 70 deg C, 1 h; 2) water, 20 deg C, 0.5 h.; Yield given. Multistep reaction;
Multi-step reaction with 3 steps 1: sodium bromide; sulfuric acid; iron(II) sulfate; iodine; dihydrogen peroxide / dichloromethane; water / 0 °C 2: potassium dichromate; sulfuric acid; copper(II) sulfate / water; acetonitrile / 45 °C 3: sodium carbonate; hydrogen / 80 °C View Scheme

: 2,3,5-trimethyl-4-hydroxybenzaldehyde

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
With sulfuric acid; dihydrogen peroxide In methanol; water at 17 - 35℃; Product distribution / selectivity; Dakin Reaction;	85%

: 79-21-0
peracetic acid

: 697-82-5
2,3,5-trimethylphenol

A: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

B: 700-13-0
Trimethylhydroquinone

C: 13038-87-4
2,3,5-trimethyl-1,6-benzoquinone

D: 20469-61-8
2,3,5-trimethylanisole

E: 34649-27-9
1-acetoxy-2,3,5-trimethylbenzene

: 5-acetoxy-2,4-dihydroxy-2,4,5-trimethyl-3,6-lacto-1-hexanoic acid

Conditions

Conditions	Yield
sulfuric acid at 50℃; for 0.5h; Mechanism; Thermodynamic data; effect of catalysts;	A 67.15% B 0.15% C n/a D 0.03% E 0.04% F 32.03%

...Expand

: 2,3,6-trimethyl-cyclohex-3-ene-1,2-diol

A: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

B: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
With silica gel; pyridinium chlorochromate In dichloromethane at 20℃; for 1h;	A n/a B 64%

: carbonic acid ethyl ester 4-hydroxy-2,3,5-trimethyl-phenyl ester

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
With sulfuric acid In methanol at 50℃;	62%

: 95-63-6
1,2,4-Trimethylbenzene

A: 16308-92-2
2,4-dimethylbenzyl alcohol

B: 700-13-0
Trimethylhydroquinone

C: 496-78-6
2,4,5-trimethylphenol

D: 53957-33-8
2,5-dimethylbenzyl alcohol

Conditions

Conditions	Yield
With glucose dehydrogenase; D-glucose; P450 BM3 R47S, Y51W mutant; NADPH; catalase; ascorbic acid In aq. phosphate buffer; dimethyl sulfoxide pH=7.5; Catalytic behavior; Enzymatic reaction;	A 31% B 12% C 34% D 12%

...Expand

: 95-63-6
1,2,4-Trimethylbenzene

A: 16308-92-2
2,4-dimethylbenzyl alcohol

B: 700-13-0
Trimethylhydroquinone

C: 496-78-6
2,4,5-trimethylphenol

D: 697-82-5
2,3,5-trimethylphenol

E: 53957-33-8
2,5-dimethylbenzyl alcohol

Conditions

Conditions	Yield
With glucose dehydrogenase; D-glucose; P450 BM3 R47S, Y51W, I401M mutant; NADPH; catalase; ascorbic acid In aq. phosphate buffer; dimethyl sulfoxide pH=7.5; Catalytic behavior; Reagent/catalyst; Enzymatic reaction;	A 17% B 32% C 31% D 7% E 7%

...Expand

: 95-63-6
1,2,4-Trimethylbenzene

A: 16308-92-2
2,4-dimethylbenzyl alcohol

B: 700-13-0
Trimethylhydroquinone

C: 496-78-6
2,4,5-trimethylphenol

D: 2416-94-6
2,3,6-trimethylphenol

E: 697-82-5
2,3,5-trimethylphenol

F: 53957-33-8
2,5-dimethylbenzyl alcohol

Conditions

Conditions	Yield
With glucose dehydrogenase; D-glucose; P450 BM3 R47S, Y51W, A330F, I401M mutant; NADPH; catalase; ascorbic acid In aq. phosphate buffer; dimethyl sulfoxide pH=7.5; Catalytic behavior; Enzymatic reaction;	A 25% B 23% C 28% D 5% E 8% F 9%

...Expand

: 81828-87-7
2-(2,4,6-trimethylphenyl)quinoline

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
With sodium hydroxide

: 103045-07-4
4-Hexadecyloxy-2,3,6-trimethyl-phenol

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
at 350 - 380℃;

: 74794-07-3
1-allyl-1-hydroxy-2,3,5-trimethylcyclohexa-2,4-dien-4-one

A: 67883-68-5
2,3,5-trimethyl-6-prop-2-enylbenzene-1,4-diol

B: 700-13-0
Trimethylhydroquinone

C: 74785-14-1
5-allyl-2,3,5-trimethylcyclohex-2-ene-1,4-dione

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In dichloromethane for 1h; Product distribution; -73 deg C to 20 deg C; other reagents, temperature;	A 44 % Spectr. B 9 % Spectr. C 47 % Spectr.

...Expand

: 74794-06-2
1-allyl-1-hydroxy-2,3,6-trimethylcyclohexa-2,4-dien-4-one

A: 67883-68-5
2,3,5-trimethyl-6-prop-2-enylbenzene-1,4-diol

B: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
In dichloromethane for 8h; Heating;	A 80 % Spectr. B 5 % Spectr.

: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

: 30771-70-1
2-p-tolyl-thio-3,5-trimethylhydroquinone

A: 700-13-0
Trimethylhydroquinone

B: 2,3,5-Trimethyl-6-p-tolylsulfanyl-[1,4]benzoquinone

Conditions

Conditions	Yield
With sodium acetate In methanol; water at 24℃; Equilibrium constant; further compound;
With sodium acetate In methanol; water at 24℃; Equilibrium constant;

...Expand

: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

: 30771-75-6
2,3,5-trimethyl-6-phenylsulfonylhydroquinone

A: 700-13-0
Trimethylhydroquinone

B: 145746-63-0
2,3,5-trimethyl-6-phenylsulfonyl-1,4-benzoquinone

Conditions

Conditions	Yield
With sodium acetate In methanol; water at 24℃; Equilibrium constant;

...Expand

: 3599-41-5
trimethyl-1,4-benzoquinone radical anion

A: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

B: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
In water at 22℃; Rate constant;

: 16404-66-3
4-hydroxy-2,4,6-trimethyl-cyclohexa-2,5-dienone

alkalies: alkalies

: 700-13-0
Trimethylhydroquinone

: 16404-66-3
4-hydroxy-2,4,6-trimethyl-cyclohexa-2,5-dienone

mineral acids: mineral acids

: 700-13-0
Trimethylhydroquinone

: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

SO2: SO2

: 700-13-0
Trimethylhydroquinone

: 39055-45-3
2-Bromo-3,5,6-trimethyl-hydroquinone

electrophile: electrophile

A: 700-13-0
Trimethylhydroquinone

B: 53711-21-0
2,5-dihydroxy-3,4,6-trimethyl-benzaldehyde

Conditions

Conditions	Yield
With n-butyllithium; N,N,N,N,-tetramethylethylenediamine 1.) THF, 5-15 deg C, sonication, 2 h, 2.) r.t., several hours; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

: 39055-45-3
2-Bromo-3,5,6-trimethyl-hydroquinone

electrophile: electrophile

A: 700-13-0
Trimethylhydroquinone

B: 83857-83-4
2,3,5-Trimethyl-6-methylsulfanyl-benzene-1,4-diol

Conditions

Conditions	Yield
With n-butyllithium; N,N,N,N,-tetramethylethylenediamine 1.) THF, 5-15 deg C, sonication, 2 h, 2.) r.t., several hours; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

A: 700-13-0
Trimethylhydroquinone

B: 2913-43-1
2-hydroxy-3,5,6-trimethyl-1,4-benzoquinone

Conditions

Conditions	Yield
In water at 24℃; Quantum yield; Further Variations:; Solvents; UV-irradiation;

: 2416-94-6
2,3,6-trimethylphenol

A: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

B: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
With dihydrogen peroxide; copper hydroxyphosphate In water; acetonitrile at 80℃; for 2h;
With dihydrogen peroxide; silica-supported P catalyst In acetonitrile at 80℃; for 2h; Product distribution; Further Variations:; Catalysts;

: 869162-36-7
acetic acid 3,6-dimethyl-2-oxo-cyclohex-3-enyl ester

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 75 percent / tetrahydrofuran; diethyl ether 2: 64 percent / PCC; SiO2 / CH2Cl2 / 1 h / 20 °C View Scheme

: 14845-35-3
2,5-dimethyl-cyclohex-2-enone

: 700-13-0
Trimethylhydroquinone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 70 percent / toluene / 4 h / Heating 2: 75 percent / tetrahydrofuran; diethyl ether 3: 64 percent / PCC; SiO2 / CH2Cl2 / 1 h / 20 °C View Scheme

: 700-13-0
Trimethylhydroquinone

: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

Conditions

Conditions	Yield
With benzyltrimethylammonium tribromide; sodium acetate In dichloromethane; water for 2h; Ambient temperature;	100%
With pyridine; 3-carboxypyridinium dichromate In dichloromethane for 0.333333h; Ambient temperature;	100%
With dihydrogen peroxide In acetic acid	100%

: 700-13-0
Trimethylhydroquinone

: 7210-68-6
2-Bromo-3,5,6-trimethyl-1,4-benzoquinone

Conditions

Conditions	Yield
With benzyltrimethylammonium tribromide In water; acetic acid at 40℃; for 5h;	100%
Multi-step reaction with 4 steps 1: Py 2: NH3 / methanol; benzene 3: NBS / methanol 4: NBS / ethanol; CHCl3 View Scheme

: 700-13-0
Trimethylhydroquinone

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With pyridine; 3-carboxypyridinium dichromate In dichloromethane for 0.333333h; Product distribution; Ambient temperature; other reagents and ratio of reagents;	100%

: 700-13-0
Trimethylhydroquinone

: 74-88-4
methyl iodide

: 4537-09-1
1,4-dimethoxy-2,3,5-trimethyl-benzene

Conditions

Conditions	Yield
Stage #1: Trimethylhydroquinone With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.166667h; Stage #2: methyl iodide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 3h;	100%
Stage #1: Trimethylhydroquinone With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1h; Stage #2: methyl iodide In N,N-dimethyl-formamide; mineral oil at 20℃; for 2.75h;	89%
With potassium carbonate In butanone at 65℃; for 72h;	82%

titanium montmorillonite: titanium montmorillonite

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

: 59-02-9
Tocopherol

Conditions

Conditions	Yield
In octane	100%

...Expand

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

: 59-02-9
vitamin E

Conditions

Conditions	Yield
With hydroxylated magnesium fluoride In 1,2-propylene cyclic carbonate; n-heptane at 100℃; for 3h;	99.9%
With nanoscopic partly hydroxylated AlF3-50 In n-heptane; propylene carbonate at 100℃; for 1h; Friedel-Crafts alkylation;	99.9%
With 2,6-di-tert-butyl-pyridine; trimethylsilyl pentafluorophenylbis(trifluoromethanesulfonyl)methide In n-heptane Heating;	97%

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

: 59-02-9
Tocopherol

Conditions

Conditions	Yield
With hydrogenchloride; Zinc chloride In tetrachloromethane	99.1%
With hydrogenchloride; sodium dithionite; Zinc chloride In toluene	99.8%
With hydrogenchloride; zinc dibromide; zinc	98.6%

: 700-13-0
Trimethylhydroquinone

: 64-19-7
acetic acid

A: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

B: 4537-09-1
1,4-dimethoxy-2,3,5-trimethyl-benzene

C: 7479-28-9
2,3,5-trimethyl-1,4-hydroquinone diacetate

D: 36592-62-8
4-acetoxy-2,3,5-trimethylphenol

E: 130422-86-5
4-methoxy-2,3,5-trimethylphenol

F: 1-acetoxy-4-methoxy-2,3,5-trimethylbenzene

Conditions

Conditions	Yield
With peracetic acid at 50℃; for 0.25h; Product distribution; Kinetics; Thermodynamic data;	A 99.7% B 0.05% C 0.05% D 0.04% E 0.04% F 0.06%

...Expand

: 110-19-0
2-methylpropyl acetate

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

: 59-02-9
Tocopherol

Conditions

Conditions	Yield
With hydrogenchloride; Zinc chloride In water; toluene	99.6%
With hydrogenchloride; Zinc chloride In water; toluene	98.6%

...Expand

: 79-21-0
peracetic acid

: 700-13-0
Trimethylhydroquinone

A: 935-92-2
2,3,5-Trimethyl-1,4-benzoquinone

B: 4537-09-1
1,4-dimethoxy-2,3,5-trimethyl-benzene

C: 7479-28-9
2,3,5-trimethyl-1,4-hydroquinone diacetate

D: 36592-62-8
4-acetoxy-2,3,5-trimethylphenol

E: 130422-86-5
4-methoxy-2,3,5-trimethylphenol

F: 1-acetoxy-4-methoxy-2,3,5-trimethylbenzene

Conditions

Conditions	Yield
sulfuric acid at 50℃; for 0.5h; Mechanism; Thermodynamic data; effect of catalysts;	A 99.5% B 0.05% C 0.06% D 0.05% E 0.04% F 0.07%

...Expand

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

: 105-58-8
Diethyl carbonate

: 59-02-9
Tocopherol

Conditions

Conditions	Yield
With hydrogenchloride; sodium chloride; Zinc chloride In water; toluene	99.2%
With hydrogen bromide; zinc dibromide In water	99.1%
With hydrogenchloride; Zinc chloride In water; toluene	98.9%

...Expand

: 700-13-0
Trimethylhydroquinone

: 77-78-1
dimethyl sulfate

: 4537-09-1
1,4-dimethoxy-2,3,5-trimethyl-benzene

Conditions

Conditions	Yield
With potassium hydroxide In methanol for 18h; Ambient temperature;	99%
With sodium hydroxide In ethanol; water; ethyl acetate at 0 - 20℃; for 2 - 4h;	88%
With potassium carbonate In acetone Heating;	82%

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

: 78-93-3
butanone

: 59-02-9
Tocopherol

Conditions

Conditions	Yield
With sodium hydroxide; sodium chloride; scandium tris(trifluoromethanesulfonate) In ethyl acetate; toluene	99%

...Expand

: 844467-81-8
(E/Z)-(all-rac)-phytyl benzoate

: 700-13-0
Trimethylhydroquinone

: 59-02-9
vitamin E

Conditions

Conditions	Yield
bismuth(lll) trifluoromethanesulfonate In Ethylene carbonate; n-heptane at 125 - 145℃; for 3.25h; Product distribution / selectivity; Heating / reflux;	98.6%

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

: 71-36-3
butan-1-ol

: 59-02-9
Tocopherol

Conditions

Conditions	Yield
With hydrogenchloride; Zinc chloride In hexane; water; toluene	98.1%
With hydrogenchloride; Zinc chloride In hexane; water; toluene	98.1%
With hydrogenchloride; Zinc chloride In hexane; water; toluene	95.9%
With hydrogenchloride; Zinc chloride In hexane; water; toluene	95.9%

...Expand

: 541-47-9
3-Methylbutenoic acid

: 700-13-0
Trimethylhydroquinone

: 40662-76-8
6-hydroxy-4,4,5,7,8-pentamethyl-3,4-dihydrocoumarin

Conditions

Conditions	Yield
With methanethiosulfonic acid at 70℃; for 1.5h;	98%
With methanesulfonic acid at 70℃; for 4h;	87%
With methanesulfonic acid at 85℃; for 3h;	85%

: 700-13-0
Trimethylhydroquinone

: isophytol

: 59-02-9
Tocopherol

Conditions

Conditions	Yield
aluminum ion-exchanged montmorilonites In octane for 3h; Product distribution; Heating; var. metal ion-exchanged montmorilonites, var. solvents, var. reaction time;	98%

: scandium fluorosulfonate

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

: 59-02-9
Tocopherol

Conditions

Conditions	Yield
With sodium chloride In ethyl acetate; toluene	98%

...Expand

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

A: 59-02-9
vitamin E

B: 85353-80-6
2-phytyl-3,5,6-trimethylhydroquinone

Conditions

Conditions	Yield
indium (III) iodide In Ethylene carbonate; n-heptane at 140 - 145℃; for 2h; Product distribution / selectivity; Heating / reflux;	A 97.3% B 0.25%
indium(III) chloride In pentan-3-one at 140 - 145℃; for 5h; Product distribution / selectivity; Heating / reflux;	A 95.1% B 0.37%
indium(III) chloride In Ethylene carbonate; n-heptane at 140 - 145℃; for 2 - 5h; Product distribution / selectivity; Heating / reflux;	A 94.8% B 0%

...Expand

: 395645-30-4
(3RS,7R,11R)-3,7,11,15-tetramethylhexadec-1-en-3-ol

: 700-13-0
Trimethylhydroquinone

: 186537-56-4
(2RS,4R,8R)-α-tocopherol

Conditions

Conditions	Yield
With Zeokar 10 aluminosilicate In various solvent(s) for 5h; Heating;	97%
With boron trifluoride In diethyl ether

: 700-13-0
Trimethylhydroquinone

: 455-88-9
5-nitro-2-fluorotoluene

: 2,3,5-Trimethyl-1,4-bis(2'-methyl-4'-nitrophenoxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide; xylene at 130 - 135℃; for 4h;	96%

: 827598-68-5
(all-rac,E)-phytyl benzoate

: 700-13-0
Trimethylhydroquinone

: 59-02-9
vitamin E

Conditions

Conditions	Yield
gadolinium(III) trifluoromethanesulfonate In Ethylene carbonate; n-heptane at 125 - 130℃; for 2.5h; Product distribution / selectivity; Heating / reflux;	95%

: 1629-58-9
4-penten-3-one

: 700-13-0
Trimethylhydroquinone

: 149-73-5
trimethyl orthoformate

: 3,4-dihydro-2-ethyl-6-hydroxy-2-methoxy-5,7,8-trimethyl-2H-1-benzopyran

Conditions

Conditions	Yield
Stage #1: Trimethylhydroquinone; trimethyl orthoformate In methanol for 0.0833333h; Inert atmosphere; Stage #2: 4-penten-3-one With sulfuric acid In methanol at 0 - 20℃; for 48h; Inert atmosphere;	95%

...Expand

: 700-13-0
Trimethylhydroquinone

: 58479-61-1
tert-butylchlorodiphenylsilane

: 108534-50-5
4-[(tert-butyldiphenylsilyl)oxy]-2,3,6-trimethylphenol

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide at -30 - 20℃; Inert atmosphere;	94%
With 1H-imidazole In tetrahydrofuran for 12h; Ambient temperature;	90%

: 700-13-0
Trimethylhydroquinone

: 78-94-4
methyl vinyl ketone

: 149-73-5
trimethyl orthoformate

: 53209-24-8
2,5,7,8-tetramethyl-2-methoxy-6-hydroxychroman

Conditions

Conditions	Yield
With sulfuric acid In methanol at 20℃; for 48h;	94%
With sulfuric acid In methanol at 20℃; for 48h;	94%
With sulfuric acid In methanol at 20℃;	64%
Stage #1: Trimethylhydroquinone; trimethyl orthoformate In methanol for 0.0833333h; Inert atmosphere; Stage #2: methyl vinyl ketone With sulfuric acid In methanol at 0 - 20℃; for 48h; Inert atmosphere;	60%

...Expand

: 505-32-8
isophytol

: 700-13-0
Trimethylhydroquinone

A: 59-02-9
vitamin E

B: 3808-26-2, 125276-57-5
(all-rac)-3,4-dehydro-α-tocopherol

Conditions

Conditions	Yield
indium(III) chloride In n-heptane at 147℃; under 2550.26 Torr; for 3.1h; Product distribution / selectivity;	A 93.7% B n/a

...Expand

Trimethylhydroquinone Consensus Reports

Reported in EPA TSCA Inventory.

Trimethylhydroquinone Specification

Trimethylhydroquinone, its cas register number is 700-13-0. It also can be called 1,4-benzenediol, 2,3,5-trimethyl-; 2,3,5-Trimethyl-1,4-benzenediol; 2,3,5-Trimethylbenzene-1,4-diol; and 2,3,5-Trimethylbenzol-1,4-diol. Its classification code is Reproductive Effect.
Trimethylhydroquinone could be stable under normal temperatures and pressures. It should avoid the condition like incompatible materials. It is not compatible with strong oxidizing agents. And also prevent it to broken down into hazardous decomposition products: carbon monoxide, carbon dioxide. However, its hazardous polymerization has not been reported.

Physical properties about Trimethylhydroquinone are: (1)ACD/LogP: 1.675; (2)ACD/LogD (pH 5.5): 1.68; (3)ACD/LogD (pH 7.4): 1.67; (4)ACD/BCF (pH 5.5): 11.03; (5)ACD/BCF (pH 7.4): 11.03; (6)ACD/KOC (pH 5.5): 194.06; (7)ACD/KOC (pH 7.4): 194.02; (8)#H bond acceptors: 2; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 2; (11)Index of Refraction: 1.573; (12)Molar Refractivity: 44.491 cm³; (13)Molar Volume: 135.119 cm³; (14)Polarizability: 17.638 10-24cm³; (15)Surface Tension: 45.140998840332 dyne/cm ; (16)Density: 1.126 g/cm³; (17)Flash Point: 146.269 °C; (18)Enthalpy of Vaporization: 55.969 kJ/mol; (19)Boiling Point: 298.253 °C at 760 mmHg; (20)Vapour Pressure: 0.00100000004749745 mmHg at 25°C

When you are using this chemical, please be cautious about it as the following:
1. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;
2. Wear suitable gloves and eye/face protection;
3. This material and/or its container must be disposed of as hazardous waste;
4. Avoid release to the environment. Refer to special instructions safety data sheet;

You can still convert the following datas into molecular structure:
(1)InChI=1S/C9H12O2/c1-5-4-8(10)6(2)7(3)9(5)11/h4,10-11H,1-3H3;
(2)InChIKey=AUFZRCJENRSRLY-UHFFFAOYSA-N;
(3)Smilesc1(c(c(cc(c1O)C)O)C)C

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	65mg/kg (65mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 125, 1993.
rabbit	LD50	skin	> 200mg/kg (200mg/kg)		BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 125, 1993.
rat	LC50	inhalation	1500mg/m3/4H (1500mg/m3)	CARDIAC: OTHER CHANGES SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE LUNGS, THORAX, OR RESPIRATION: EMPHYSEMA	BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 125, 1993.
rat	LD50	oral	3200mg/kg (3200mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 125, 1993.

Product Name

Trimethylhydroquinone

Synthetic route

Trimethylhydroquinone Consensus Reports

Trimethylhydroquinone Specification

Related Products

Hot Products