Urethane supplier | CasNO.51-79-6

Name
Urethane
EINECS 200-123-1
CAS No. 51-79-6
Article Data185
CAS DataBase
Density 1.045 g/cm³
Solubility slightly soluble
Melting Point 48-50 °C(lit.)
Formula C₃H₇NO₂
Boiling Point 184 °C at 760 mmHg
Molecular Weight 89.0941
Flash Point 97.2 °C
Transport Information
Appearance COA
Safety 53-45-99
Risk Codes 45
Molecular Structure
Hazard Symbols T
Synonyms Ethylaminoformate;Ethyl carbamate;Ethylurethane;Leucethane;O-Ethylurethane;Pracarbamine;
PSA 52.32000
LogP 0.80190

Synthetic route

: 110-82-7
cyclohexane

: 66121-61-7
N,O-bistrimethylsilyl-N-(ethoxycarbonyl)hydroxylamine

A: 107-46-0
Hexamethyldisiloxane

B: 1541-19-1
ethyl N-cyclohexylcarbamate

C: 51-79-6
urethane

Conditions

Conditions	Yield
at 100℃; for 25h;	A 100% B 80% C 8%
at 45℃; for 58h; Irradiation;	A 75% B 45% C 55%

...Expand

: 64-17-5
ethanol

: 57-13-6
urea

: 51-79-6
urethane

Conditions

Conditions	Yield
With alumina supported chromium oxide-nickel oxide-bismuth oxide trimetal oxide catalyst at 90℃; for 12h; Sealed tube;	99.1%
at 179.84℃; for 7h; Autoclave;	90%

: 75934-53-1
ethyl-N-(carboethoxy)-N-nitrocarbamate

A: 62258-40-6
N-nitrouretahne ammonium salt

B: 51-79-6
urethane

Conditions

Conditions	Yield
With ammonia In acetonitrile for 0.0833333h;	A 99% B 0.15 g

: trichloroethoxycarbonyl chloride

: 51-79-6
urethane

Conditions

Conditions	Yield
sodium hydrogencarbonate	96%

: 24482-75-5
Dichloronitroacetic acid ethyl ester

: 51-79-6
urethane

Conditions

Conditions	Yield
With ammonium hydroxide for 48h; Ambient temperature;	91%

: 64-17-5
ethanol

: 917-61-3
sodium isocyanate

: 51-79-6
urethane

Conditions

Conditions	Yield
With hydrogenchloride In dichloromethane at -2 - 2℃; for 6h;	90%
With perchloric acid on silica gel at 20℃; for 0.75h;	73%

: 60-29-7
diethyl ether

: 2746-25-0
p-Methoxybenzyl bromide

: 51-79-6
urethane

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide; Petroleum ether; benzene	90%

: (Z,E)-N2-(ethoxycarbonyl)-N1-methyl-N1-octylformamidine

A: 36600-01-8
N-methyl-N-octylformamide

B: 51-79-6
urethane

Conditions

Conditions	Yield
With acetic acid In 1,4-dioxane at 20℃; for 1h;	A 89% B n/a

: 1-Ethoxycarbonylamino-2,4,6-trimethyl-pyridinium; perchlorate

A: 108-75-8
2,4,6-trimethyl-pyridine

B: C11H16N2O2

C: 51-79-6
urethane

Conditions

Conditions	Yield
With tetraethylammonium perchlorate In acetonitrile preparative electrolyse, - 2.3 V;	A 87% B n/a C n/a

...Expand

: 2Rh(1+)*4CO*2NCO(1-)=[Rh(CO)2NCO]2

A: hexarhodium hexadecacarbonyl

B: 51-79-6
urethane

Conditions

Conditions	Yield
With ethanol; carbon monoxide In ethanol to degassed ethanol educt added with stirring while CO bubled through for 15 h; product filtered off, washed with ethanol and hexane, dried in vac.; elem. anal.;	A 85% B n/a

: (Z,E)-N2-(ethoxycarbonyl)-N1-methyl-N1-dodecylformamidine

A: 76058-02-1
N-methyl-N-1-dodecylformamide

B: 51-79-6
urethane

Conditions

Conditions	Yield
With acetic acid In 1,4-dioxane at 20℃; for 1h;	A 83% B n/a

: 95-92-1
oxalic acid diethyl ester

: 57-13-6
urea

A: 617-36-7
Ethyl oxamate

B: 51-79-6
urethane

Conditions

Conditions	Yield
With di(n-butyl)tin oxide at 140℃; for 12h; Inert atmosphere;	A 80% B 80%
With di(n-butyl)tin oxide at 140℃; under 2585.81 Torr; for 12h; Inert atmosphere; Autoclave;	A 30 %Chromat. B 60 %Chromat.

...Expand

: 590-28-3
potassium cyanate

: 64-17-5
ethanol

: 51-79-6
urethane

Conditions

Conditions	Yield
With para-dodecylbenzenesulfonic acid In neat (no solvent) at 60℃; for 0.5h; Green chemistry;	79%
With hydrogenchloride Darst, dann neutralisiert man mit Bariumcarbonat;
With DBSA at 60℃; for 1h;
With DBSA at 60℃; for 1h;
With DBSA at 60℃; for 1h;

: 90454-50-5
N-ethoxycarbonyl-(2,3,4,5-tetrachloro-1-thiophenio)amide

A: 6012-97-1
2,3,4,5-tetrachlorothiophene

B: 51-79-6
urethane

Conditions

Conditions	Yield
With hydrogen; nickel In tetrahydrofuran for 4h;	A 61% B 68%
With hydrogen; nickel Product distribution;	A n/a B 68%

: 64-17-5
ethanol

: 57-13-6
urea

A: 51-79-6
urethane

B: 105-58-8
Diethyl carbonate

Conditions

Conditions	Yield
With MgZn1.7Al hydrotalcite calcined at 450°C at 200℃; under 15001.5 Torr; for 4h; Catalytic behavior; Reagent/catalyst; Autoclave;	A 18% B 68%
With calcined Y(NO3)3x6H2O; calcined Y(NO3)3x6H2O at 180℃; under 11096.7 Torr; for 4h; Inert atmosphere; Autoclave;	A 11.2% B 62.4%
With Mg2Zr0.53Al0.47 mixed metal oxides at 200℃; for 5h; Reagent/catalyst; Temperature;	A 45.3% B 37.6%

...Expand

: 109-02-4
4-methyl-morpholine

: 817-87-8
ethyl azidocarbonate

A: 58050-49-0
4-(ethoxycarbonylaminomethyl)morpholine

B: 75256-50-7
4-methyl-3-(ethoxycarbonylamino)morpholine

C: 51-79-6
urethane

Conditions

Conditions	Yield
at 115℃; for 3h; Further byproducts given;	A 13.4% B 2.5% C 61.1%

...Expand

: 64-17-5
ethanol

: 2911-21-9
2,4-dioxo-6-methyl-3,4-dihydro-2H-1,3-oxazine

A: 141-97-9
ethyl acetoacetate

B: 51-79-6
urethane

Conditions

Conditions	Yield
With triethylamine for 24h; Heating;	A 60% B 12%
With triethylamine Heating; Yield given;

...Expand

: 66121-61-7
N,O-bistrimethylsilyl-N-(ethoxycarbonyl)hydroxylamine

: 71-43-2
benzene

A: 2955-79-5
N-ethoxycarbonylazepine

B: 51-79-6
urethane

Conditions

Conditions	Yield
at 90℃; for 75h;	A 57% B n/a

...Expand

: 625-57-0
O-ethyl thiocarbamate

A: 4115-25-7
3,5-diethoxy-1,2,4-thiadiazole

B: 75-00-3
chloroethane

C: 51-79-6
urethane

D: 178318-21-3
3-ethoxy-1,2,4-dithiazole-5-one

Conditions

Conditions	Yield
With chloro(chlorosulfanyl)methanone; triethylamine In chloroform at 5 - 10℃; for 0.25h;	A 54% B 17% C 3% D 7%

...Expand

: 817-87-8
ethyl azidocarbonate

: 106-42-3
para-xylene

A: 30559-02-5
2,5-dimethyl-azepine-1-carboxylic acid ethyl ester

B: 76917-05-0
ethyl 2,5-dimethylphenylcarbamate

C: 76917-04-9
3,6-Dimethyl-azepine-1-carboxylic acid ethyl ester

D: 51-79-6
urethane

Conditions

Conditions	Yield
Heating;	A 53% B 7% C 34% D 2%
cobalt(II) 5,10,15,20-tetraphenylporphyrin Product distribution; Heating; others catalysts;

...Expand

: 75633-16-8
1-ethoxycarbonyl-5-methyl-1H-1,3-diazepine

A: 37772-60-4
5-hydroxy-3-methyl-1,5-dihydropyrrol-2-one

B: 18804-91-6
ethyl N-carbonylcarbamate

C: 91024-61-2
1-formyl-5-hydroxy-3-methyl-3-pyrrolin-2-one

D: 51-79-6
urethane

Conditions

Conditions	Yield
With 5,10,15,20-tetrakisphenylporphyrin; oxygen In tetrachloromethane for 2h; Ambient temperature; Irradiation;	A 53% B 32% C 19% D 18%
With 5,10,15,20-tetrakisphenylporphyrin; water; oxygen 1.) carbon tetrachloride, irradiation, 30 min; 2.) tetrahydrofuran, r.t., 6 h; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

: 20160-60-5
2-(trimethylsilyl)-ethoxycarbonyl chloride

: 5468-37-1
2-aminoacetophenone hydrochloride

: 51-79-6
urethane

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran	53%
With triethylamine In tetrahydrofuran	53%

: 57492-79-2
N-(2,4-dimethyl-6,7-methylenedioxy-3-quinazolinio)-ethoxyformamidate

A: 66117-80-4
(6-methyl-[1,3]dioxolo[4,5-g]quinazolin-8-ylmethyl)-carbamic acid ethyl ester

B: 66117-79-1
1,2-bis(2-methyl-6,7-methylenedioxy-4-quinazolinyl)ethane

C: 51-79-6
urethane

D: [1,2-Bis-(6-methyl-[1,3]dioxolo[4,5-g]quinazolin-8-yl)-ethyl]-carbamic acid ethyl ester

E: 57492-84-9
2,4-dimethyl-6,7-methylenedioxyquinazoline

Conditions

Conditions	Yield
In 1,4-dioxane for 80h; Mechanism; Heating; other solvent and temperature, other substrate;	A 5% B 1.4% C n/a D 15% E 51%

...Expand

: 50-00-0
formaldehyd

: 51-79-6
urethane

: 5027-16-7
ethyl N-(hydroxymethyl)carbamate

Conditions

Conditions	Yield
With potassium carbonate In benzene at 70 - 75℃; for 3.5h;	100%
With barium dihydroxide In water for 40h; Ambient temperature;	38%
With barium dihydroxide

: 684-16-2
Hexafluoroacetone

: 51-79-6
urethane

: 19396-71-5
(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-carbamic acid ethyl ester

Conditions

Conditions	Yield
for 72h; Ambient temperature;	100%
With toluene-4-sulfonic acid In dichloromethane

: 930-68-7
cyclohexenone

: 51-79-6
urethane

: 38031-97-9
β-ethyloxycarbonylamino-cyclohexanone

Conditions

Conditions	Yield
With chloro-trimethyl-silane; tributylphosphine In dichloromethane at 20℃; for 15h; aza-Michael reaction;	100%
With boron trifluoride diethyl etherate; tetrabutylammomium bromide In dichloromethane at 20℃; for 24h; aza-Michael reaction;	95%
With chloro-trimethyl-silane; iron(III) chloride In dichloromethane at 20℃; for 10h; aza-Michael reaction;	93%

: (4-methoxy-phenyl)-[4-(3,4,5-tris-octadecyloxy-cyclohexylmethoxy)-phenyl]-methanol

: 51-79-6
urethane

: ethyl {(4-methoxy-phenyl)-[4-(3,4,5-tris-octadecyloxy-cyclohexylmethoxy)-phenyl]-methyl}-carbamate

Conditions

Conditions	Yield
With methanesulfonic acid In toluene at 110℃; for 2h;	100%

: 1246541-59-2
bis[4-(docosyloxy)phenyl]methyl alcohol

: 51-79-6
urethane

: 1394992-05-2
ethyl [bis-(4-docosoxyphenyl)methyl]carbamate

Conditions

Conditions	Yield
With methanesulfonic acid In toluene at 110℃; for 2.5h;	100%
With methanesulfonic acid In toluene at 110℃; for 3h;	99%

: 76-84-6
triphenylmethyl alcohol

: 51-79-6
urethane

: 102459-48-3
trityl-carbamic acid ethyl ester

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In benzene for 3h; Heating;	99%

: 50-00-0
formaldehyd

: 64-86-8
colchicine

: 51-79-6
urethane

: ethyl {[(7S)-7-(acetylamino)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-4-yl]methyl}carbamate

Conditions

Conditions	Yield
Stage #1: formaldehyd; urethane With sulfuric acid; water at 20℃; for 0.166667h; Stage #2: colchicine at 20℃; for 4h;	99%

...Expand

: 4663-33-6, 62668-02-4, 62839-70-7, 116127-91-4, 132014-29-0, 136981-81-2, 148616-45-9
1,3-diphenyl-3-hydroxypropene

: 51-79-6
urethane

: 1374561-60-0
(E)-ethyl (1,3-diphenylallyl)carbamate

Conditions

Conditions	Yield
With perrhenic acid anhydride In dichloromethane at 20℃; for 1h;	99%

: 5798-75-4
Ethyl 4-bromobenzoate

: 51-79-6
urethane

: 5100-21-0
4-benzoesaure-ethylester

Conditions

Conditions	Yield
With di-tert-butyl(2,2-diphenyl-1-methyl-1-cyclopropyl)phosphine; bis(η3-allyl-μ-chloropalladium(II)); sodium t-butanolate In water at 50℃; for 24h; Inert atmosphere; Green chemistry;	99%

: 73930-97-9
3-acetoxy-1,3-diphenylpropene

: 51-79-6
urethane

A: C18H19NO2

B: C18H19NO2

Conditions

Conditions	Yield
With potassium phosphate; bis(η3-allyl-μ-chloropalladium(II)); (2S,3S,5R,6R)-2,3-bis(2-(diphenylphosphino)phenyl)-1,4-dimethyldecahydroquinoxaline In N,N-dimethyl acetamide at 20℃; for 12h; enantioselective reaction;	A 99% B n/a

...Expand

: 1745-46-6
6,11-dihydrodibenzo[b,e]thiepin-11-ol

: 51-79-6
urethane

: 74797-18-5
ethyl N-(6,11-dihydrodibenzothiepin-11-yl)carbamate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In acetic acid 1) 37 deg C, 6h; 2) room temp., overnight;	98%

: 53662-58-1
1,1-dimethoxy-pentan-2-ol

: 51-79-6
urethane

: 104681-97-2
(2-Oxo-pentyl)-carbamic acid ethyl ester

Conditions

Conditions	Yield
With hydrogenchloride In benzene for 1h; Heating;	98%

: 124-09-4
1,6-Hexanediamine

: 64-17-5
ethanol

: 51-79-6
urethane

: 3066-65-7
1,6-bis-(ethoxycarbonylamino)-hexane

Conditions

Conditions	Yield
With 5.1 wt% Ni/Fe3O4 at 190℃; under 11251.1 - 16501.7 Torr; for 5h; Autoclave; Inert atmosphere;	98%

...Expand

: 124-22-1
n-Dodecylamine

: 64-17-5
ethanol

: 51-79-6
urethane

: 6268-50-4
ethyl-N-dodecylurethane

Conditions

Conditions	Yield
With 5.1 wt% Ni/Fe3O4 at 190℃; under 11251.1 - 16501.7 Torr; for 5h; Autoclave; Inert atmosphere;	98%

...Expand

: 64-17-5
ethanol

: 107-11-9
1-amino-2-propene

: 51-79-6
urethane

: 5325-60-0
ethyl N-allylcarbamate

Conditions

Conditions	Yield
With 5.1 wt% Ni/Fe3O4 at 190℃; under 11251.1 - 16501.7 Torr; for 5h; Autoclave; Inert atmosphere;	98%

...Expand

: 625-33-2
3-penten-2-one

: 51-79-6
urethane

: 1353002-67-1
ethyl 4-oxopentan-2-ylcarbamate

Conditions

Conditions	Yield
With 1-methyl-imidazolium p-toluenesulfonic acid at 20℃; for 16h; Michael addition; neat (no solvent);	98%

: 7745-93-9
2-bromo-4-nitrotoluene

: 51-79-6
urethane

: 16648-52-5
ethyl (2-methyl-5-nitrophenyl)carbamate

Conditions

Conditions	Yield
With di-tert-butyl(2,2-diphenyl-1-methyl-1-cyclopropyl)phosphine; bis(η3-allyl-μ-chloropalladium(II)); triisopropylsilanol; potassium hydroxide In water at 50℃; for 24h; Inert atmosphere; Green chemistry;	98%

: 90-90-4
(4-bromophenyl)(phenyl)methanone

: 51-79-6
urethane

: 289471-18-7
ethyl (4-benzoylphenyl)carbamate

Conditions

Conditions	Yield
With di-tert-butyl(2,2-diphenyl-1-methyl-1-cyclopropyl)phosphine; bis(η3-allyl-μ-chloropalladium(II)); sodium t-butanolate In water at 50℃; for 24h; Inert atmosphere; Green chemistry;	98%
With di-tert-butyl(2,2-diphenyl-1-methyl-1-cyclopropyl)phosphine; bis(η3-allyl-μ-chloropalladium(II)); TPGS-750-M; sodium t-butanolate In water at 50℃; for 24h; Reagent/catalyst; Inert atmosphere; Sealed tube;	96%

: 292638-84-7
styrene

: 39652-06-7
benzenetellurinyl acetate

: 51-79-6
urethane

: 112476-38-7
ethyl <1-phenyl-2-(phenyltelluro)ethyl>carbamate

Conditions

Conditions	Yield
boron trifluoride diethyl etherate In chloroform for 20h; Product distribution; Heating; further educts and catalysts;	97%
boron trifluoride diethyl etherate In chloroform for 20h; Heating;	97%
With boron trifluoride diethyl etherate; hydrazine hydrate 1.) CHCl3, reflux, 20 h; 2.) EtOH, 60 deg C, 15 min; Yield given. Multistep reaction;

...Expand

: 122-60-1
Phenyl glycidyl ether

: 51-79-6
urethane

A: 71031-03-3
(2R)-1,2-epoxy-3-phenoxypropane

B: ((S)-2-hydroxy-3-phenoxypropyl)carbamic acid ethyl ester

Conditions

Conditions	Yield
With air; 4-nitro-benzoic acid; [(S,S)-N,N’-bis(3,5-di-tertbutylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(II) In various solvent(s) at 20℃; for 24h;	A n/a B 97%

...Expand

: 51-79-6
urethane

: 177896-09-2
tert-butyl benzylidenecarbamate

: (+/-)-tert-butyl urethanyl(phenyl)methylcarbamate

Conditions

Conditions	Yield
With bis(trifluoromethanesulfonyl)amide In diethyl ether at 20℃; for 0.333333h;	97%

: 99-61-6
3-nitro-benzaldehyde

: 51-79-6
urethane

: 135-19-3
β-naphthol

: 1372764-64-1
ethyl ((3-nitrophenyl)(2-hydroxynaphthalen-1-yl)methyl) carbamate

Conditions

Conditions	Yield
With copper(II) choride dihydrate In neat (no solvent) at 70℃; for 0.5h;	97%
With tin (IV) chloride pentahydrate In neat (no solvent) at 60℃; for 0.1h;	95%
With 1-methyl-2-oxopyrrolidinium hydrogen sulfate at 125℃; for 0.15h;	93%
With Tween 20 In water at 75 - 80℃; for 0.5h;	90%

...Expand

: 104-95-0
(4-bromophenyl)thioanisole

: 51-79-6
urethane

: 501679-13-6
ethyl (4-methylthiophenyl)carbamate

Conditions

Conditions	Yield
With di-tert-butyl(2,2-diphenyl-1-methyl-1-cyclopropyl)phosphine; bis(η3-allyl-μ-chloropalladium(II)); triisopropylsilanol; potassium hydroxide In water at 50℃; for 24h; Inert atmosphere; Green chemistry;	97%

: 1122-91-4
4-bromo-benzaldehyde

: 51-79-6
urethane

: 20131-85-5
N-(4-formylphenyl)carbamic acid ethyl ester

Conditions

Conditions	Yield
With caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 80℃;	96.3%

: 95-14-7
1,2,3-Benzotriazole

: 6000-59-5
glyoxalic acid monohydrate

: 51-79-6
urethane

: ethoxycarbonyl-(1-benzotriazolyl)glycine

Conditions

Conditions	Yield
In toluene	96%

...Expand

Urethane Consensus Reports

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1974,p. 111.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Community Right-To-Know List. Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Urethane Standards and Recommendations

DFG MAK: Animal Carcinogen, Suspected Human Carcinogen

Urethane Specification

The Urethane with CAS registry number of 51-79-6 is also called Carbamic acid, ethylester. Its EINECS registry number is 200-123-1. The IUPAC name is ethyl carbamate. In addition, the molecular formula is C₃H₇NO₂ and the molecular weight is 89.09. It is a kind of white crystalline powder. And it is incompatible with strong acids, strong bases and strong oxidizing agents.

Physical properties about this chemical are: (1)ACD/LogP: -0.15; (2)ACD/LogD (pH 5.5): -0.15; (3)ACD/LogD (pH 7.4): -0.15; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 19.74; (7)ACD/KOC (pH 7.4): 19.74; (8)#H bond acceptors: 3; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 2; (11)Polar Surface Area: 29.54 Å²; (12)Index of Refraction: 1.413; (13)Molar Refractivity: 21.25 cm³; (14)Molar Volume: 85.2 cm³; (15)Polarizability: 8.42 ×10^-24cm³; (16)Surface Tension: 33.6 dyne/cm; (17)Density: 1.045 g/cm³; (18)Flash Point: 97.2 °C; (19)Enthalpy of Vaporization: 42.03 kJ/mol; (20)Boiling Point: 184 °C at 760 mmHg; (21)Vapour Pressure: 0.748 mmHg at 25°C.

Preparation of Urethane: it can be prepared by urea nitrate, ethanol and sodium nitrite in the presence of sulfuric acid. This reaction is a kind of esterification reaction. Then go through the operation of distillation, crystallization and drying to get the products. In addition, it can be prepared by ethanol and cyanic acid;sodium cyanate. This reaction will need reagent HCl and solvent CH₂Cl₂. The reaction time is 6 hours at reaction temperature of -2 - 2 °C. The yield is about 90%.

Urethane can be prepared by ethanol and cyanic acid;sodium cyanate.

Uses of Urethane: this chemical can be used as intermediates for medicine, pesticides and perfume. And it is used for biochemical research and the production of sleeping pills and tranquilizers. Moreover, it can be used as fungicides, cosolvent of injection and colorants in dyeing industry. In addition, it can be used to get isocyanatophosphoric acid-dichloride. This reaction will need reagent PCl₅ and solvent CH₂Cl₂. The reaction time is 4 hours by heating. The yield is about 65%.

Urethane can be used to get isocyanatophosphoric acid-dichloride

When you are using this chemical, please be cautious about it as the following:
This chemical may cause cancer. Avoid exposure-obtain special instructions before use. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.). In addition, you should keep container in a well-ventilated place.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(OCC)N
(2)InChI: InChI=1/C3H7NO2/c1-2-6-3(4)5/h2H2,1H3,(H2,4,5)
(3)InChIKey: JOYRKODLDBILNP-UHFFFAOYAY

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
chicken	LDLo	oral	2188mg/kg (2188mg/kg)		"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
guinea pig	LDLo	intraarterial	800mg/kg (800mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig	LDLo	intravenous	800mg/kg (800mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
mouse	LD50	intraperitoneal	1539mg/kg (1539mg/kg)		Progress in Mutation Research. Vol. 1, Pg. 682, 1981.
mouse	LD50	intravenous	500mg/kg (500mg/kg)		Acta Pharmaceutica Jugoslavica. Vol. 5, Pg. 43, 1955.
mouse	LD50	oral	2500mg/kg (2500mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 595, 1959.
mouse	LD50	subcutaneous	1750mg/kg (1750mg/kg)		Gann. Japanese Journal of Cancer Research. Vol. 63, Pg. 731, 1972.
mouse	LD50	unreported	2gm/kg (2000mg/kg)		British Journal of Cancer. Vol. 6, Pg. 160, 1952.
mouse	LDLo	parenteral	1gm/kg (1000mg/kg)	GASTROINTESTINAL: PERITONITIS	Progress Report for Contract No. PH-43-63-1132, Submitted to the National Cancer Institute by Scientific Associates, Inc. Vol. PH-43-62-483,
pigeon	LDLo	oral	800mg/kg (800mg/kg)		"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
rabbit	LDLo	intravenous	2gm/kg (2000mg/kg)		"Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 272, 1973.
rat	LD50	intramuscular	1400mg/kg (1400mg/kg)		Zeitschrift fuer Krebsforschung und Klinische Onkologie. Vol. 84, Pg. 227, 1975.
rat	LD50	intraperitoneal	1500mg/kg (1500mg/kg)		Cancer Research. Vol. 26, Pg. 1448, 1966.
rat	LD50	oral	1809mg/kg (1809mg/kg)		Cancer Letters Vol. 57, Pg. 37, 1991.
rat	LDLo	subcutaneous	1800mg/kg (1800mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 182, Pg. 348, 1936.

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