Product Name

  • Name

    Zeaxanthin

  • EINECS 205-636-4
  • CAS No. 144-68-3
  • Article Data50
  • CAS DataBase
  • Density 1.008 g/cm3
  • Solubility insoluble in water
  • Melting Point 203-205 °C
  • Formula C40H56O2
  • Boiling Point 711.4 °C at 760 mmHg
  • Molecular Weight 568.883
  • Flash Point 273.4 °C
  • Transport Information
  • Appearance yellow crystalline solid
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 144-68-3 (Zeaxanthin)
  • Hazard Symbols
  • Synonyms all-trans-Anchovyxanthin;all-trans-Zeaxanthin;Zeaxanthin(7CI);b-Carotene-3,3'-diol, (3R,3'R)-all-trans- (6CI,8CI);(3R,3'R)-Zeaxanthin;Anchovyxanthin;Anchovyxanthin, all-trans-;Xanthophyll 3;ZeaGold;Zeaxanthin,all-trans-;Zeaxanthol;
  • PSA 40.46000
  • LogP 10.54740

Synthetic route

all-trans lutein
7481-64-3

all-trans lutein

zeaxanthin
144-68-3

zeaxanthin

Conditions
ConditionsYield
With ethanol; sodium ethanolate; benzene at 100 - 110℃;
3,3'-di-keto-β-carotene
14656-56-5, 26543-85-1

3,3'-di-keto-β-carotene

aluminum isopropoxide
555-31-7

aluminum isopropoxide

isopropyl alcohol
67-63-0

isopropyl alcohol

benzene
71-43-2

benzene

zeaxanthin
144-68-3

zeaxanthin

(2E,4E,6E,8E,10E,12E,14E)-15-(4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-4,9,13-trimethylpentadeca-2,4,6,8,10,12,14-heptaenal
15486-31-4

(2E,4E,6E,8E,10E,12E,14E)-15-(4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-4,9,13-trimethylpentadeca-2,4,6,8,10,12,14-heptaenal

<3-(4-hydroxy-2,2,6-trimethylcyclohexenyl)-1-methyl-2-propen-1-yl>triphenylphosphonium bromide

<3-(4-hydroxy-2,2,6-trimethylcyclohexenyl)-1-methyl-2-propen-1-yl>triphenylphosphonium bromide

zeaxanthin
144-68-3

zeaxanthin

Conditions
ConditionsYield
With potassium hydroxide In isopropyl alcohol at 20℃; for 3h;8.5 mg
zeaxanthin radical cation

zeaxanthin radical cation

zeaxanthin
144-68-3

zeaxanthin

Conditions
ConditionsYield
With TX-100 In water Rate constant; Irradiation;
4',5'-didehydro-4,5'-retro-β,β-carotene-3,3'-dione
116-30-3

4',5'-didehydro-4,5'-retro-β,β-carotene-3,3'-dione

A

zeaxanthin
144-68-3

zeaxanthin

B

lutein
127-40-2

lutein

C

(3R,3'S,6'R)-lutein
89673-72-3

(3R,3'S,6'R)-lutein

Conditions
ConditionsYield
With tellurium; sodium tetrahydroborate In carbon disulfide; ethanol at 40℃; for 0.333333h; Title compound not separated from byproducts;A 24 % Chromat.
B 44 % Chromat.
C 31 % Chromat.
With tellurium; sodium tetrahydroborate In carbon disulfide; ethanol at 40℃; for 0.333333h;A 24 % Chromat.
B 44 % Chromat.
C 31 % Chromat.
lycopene
502-65-8

lycopene

zeaxanthin radical cation

zeaxanthin radical cation

A

zeaxanthin
144-68-3

zeaxanthin

B

lycopene radical cation

lycopene radical cation

Conditions
ConditionsYield
In benzene Rate constant; pulse radiolysis;
all-trans-β-carotenedione-(3,3')

all-trans-β-carotenedione-(3,3')

zeaxanthin
144-68-3

zeaxanthin

Conditions
ConditionsYield
With aluminum isopropoxide; isopropyl alcohol; benzene
(E)-4,9-dimethyl-2,4,6,8,10-dodecapentaene-1,12-dial
53163-53-4

(E)-4,9-dimethyl-2,4,6,8,10-dodecapentaene-1,12-dial

4-triphenylphosphoranylidene-pent-2t(?)-enoic acid methyl ester

4-triphenylphosphoranylidene-pent-2t(?)-enoic acid methyl ester

zeaxanthin
144-68-3

zeaxanthin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C
2: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
4-(1,4-dihydroxy-2,2,6-trimethylcyclohexyl)-3-butyn-2-ol
32469-38-8

4-(1,4-dihydroxy-2,2,6-trimethylcyclohexyl)-3-butyn-2-ol

zeaxanthin
144-68-3

zeaxanthin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 3.5 g / lithium aluminium hydride / tetrahydrofuran / 3 h / Heating
2: 2.21 g / CHCl3 / 18 h / 20 °C
3: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C
4: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 3.5 g / lithium aluminium hydride / tetrahydrofuran / 3 h / Heating
2: 2.21 g / CHCl3 / 18 h / 20 °C
3: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
4-(4-hydroxy-2,2,6-trimethylcyclohexylidene)-3-buten-2-ol
53342-69-1

4-(4-hydroxy-2,2,6-trimethylcyclohexylidene)-3-buten-2-ol

zeaxanthin
144-68-3

zeaxanthin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 2.21 g / CHCl3 / 18 h / 20 °C
2: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C
3: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 2.21 g / CHCl3 / 18 h / 20 °C
2: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
<3-(4-hydroxy-2,2,6-trimethylcyclohexenyl)-1-methyl-2-propen-1-yl>triphenylphosphonium bromide

<3-(4-hydroxy-2,2,6-trimethylcyclohexenyl)-1-methyl-2-propen-1-yl>triphenylphosphonium bromide

zeaxanthin
144-68-3

zeaxanthin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C
2: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme

Zeaxanthin Chemical Properties

IUPAC Name: (1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol   
Synonyms of Zeaxanthin (CAS NO.144-68-3): 3R 3'R Zeaxanthin ; (3R,3'R)-beta,beta-Carotene-3,3'-diol
CAS NO: 144-68-3
Molecular Formula: C40H56O2
Molecular Weight: 568.88
Molecular Structure:
EINECS: 205-636-4 
H bond acceptors: 2
H bond donors: 2
Freely Rotating Bonds: 12
Polar Surface Area: 18.46 Å2
Index of Refraction: 1.585
Molar Refractivity: 189.11 cm3
Molar Volume: 564.1 cm3
Surface Tension: 41.2 dyne/cm
Density: 1.008 g/cm3
Flash Point: 273.4 °C
Enthalpy of Vaporization: 118.87 kJ/mol
Boiling Point: 711.4 °C at 760 mmHg
Vapour Pressure: 2.19E-23 mmHg at 25°C 
Melting Point: 203-205°C
Storage temp: -20°C
Appearance: Yellow Crystalline Solid
Product Categories of Zeaxanthin (CAS NO.144-68-3): Carotenoids;Intermediates & Fine Chemicals;Pharmaceuticals

Zeaxanthin Uses

 Zeaxanthin (CAS NO.144-68-3) is used as a food additive, zeaxanthin is a food dye with E number E161h.

Zeaxanthin Safety Profile

 F: 3-8-10

Zeaxanthin Specification

Natural occurrence of Zeaxanthin (CAS NO.144-68-3): 
 Zeaxanthin is one of the most common carotenoid alcohols found in nature. It is the pigment that gives paprika (made from bell peppers), corn, saffron, and many other plants their characteristic color and Zeaxanthin breaks down to form picrocrocin and safranal, which are responsible for the taste and aroma of saffron.

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