Zinc cyanide supplier | CasNO.557-21-1

Name
ZINC CYANIDE
EINECS 209-162-9
CAS No. 557-21-1
Article Data62
CAS DataBase
Density 1.85 g/cm³
Solubility Soluble in alkalies, potassium cyanide and ammonia. Insoluble in water and most solvents.
Melting Point 800 °C
Formula C₂N₂Zn
Boiling Point 25.7 °C at 760 mmHg
Molecular Weight 117.425
Flash Point
Transport Information UN 1713
Appearance white to off-white powder
Safety 7-61-60-45-29-28
Risk Codes 50/53-32-26/27/28
Molecular Structure
Hazard Symbols N,T+
Synonyms Zinccyanide (6CI,7CI,8CI);Zinc dicyanide;
PSA 47.58000
LogP 0.03106

Synthetic route

: 773837-37-9
sodium cyanide

: zinc(II) nitrate hexahydrate

A: 557-21-1
zinc(II) cyanide

B: sodium fluoride

Conditions

Conditions	Yield
In water compds. dissolved in degassed H2O at 80°C, allowed to stand for 1d at 4°C; NaF filtered off, washed with ice-cold EtOH, aq. EtOH mixt. evapd.;	A 78% B n/a

...Expand

: 6Zn(H2NC2H4NH2)3(2+)*Cu5(CN)17(12-)*8.4H2O=[Zn(H2NC2H4NH2)3]6[Cu5(CN)17]*8.4H2O

A: 557-21-1
zinc(II) cyanide

: zincite

C: copper(l) cyanide

D: 12775-96-1, 15158-11-9, 15721-63-8, 16941-75-6, 17493-86-6, 19498-52-3, 20499-83-6, 20499-84-7, 20499-85-8, 20499-86-9, 20573-10-8, 20573-11-9, 21595-51-7, 21595-52-8, 22206-52-6, 26445-28-3, 28959-95-7, 37362-93-9, 39417-05-5, 54603-16-6, 54603-23-5, 54603-32-6, 54603-40-6, 54603-48-4, 54603-81-5, 54603-89-3, 56316-56-4, 95985-91-4, 122297-32-9, 7440-50-8
copper

Conditions

Conditions	Yield
With air In neat (no solvent) sample heating at 4 K/min in air to 300°C, temp. keeping for 3 h; XRD;	A n/a B 1% C n/a D 1%

...Expand

: 460-19-5
ethanedinitrile

: 7440-66-6
zinc

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
slow react. of liq. (CN)2 with Zn at higher temp. up to 115°C; deposition of paracyan layer on Zn is stopping react.; O2 is inhibiting react., benzene vapor and CO2 have no influence on react.;;
Kinetics; at 22°C very slow, studies on influence of temp.; inhibited by O2;
In neat (no solvent) formation on Zn-surface in the cold after several days, at 100 °C after 3 - 4 h;;

: hydrogen cyanide; compound of sodium cyanide with copper cyanide

A: 557-21-1
zinc(II) cyanide

B: copper(l) cyanide

Conditions

Conditions	Yield
With zinc(II) sulfate byproducts: Na2SO4; calcd. amts. of ZnSO4;
With ZnSO4 byproducts: Na2SO4; calcd. amts. of ZnSO4;

: 773837-37-9
sodium cyanide

: 7646-85-7
zinc(II) chloride

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In neat (no solvent) byproducts: N2; at 550°C, although evolving of N2 but no formation of cyanamide;;
pptn.;;
In neat (no solvent) byproducts: N2; at 550°C, although evolving of N2 but no formation of cyanamide;;
pptn.;;

: 460-19-5
ethanedinitrile

: 7440-66-6
zinc

A: 557-21-1
zinc(II) cyanide

B: 2074-87-5
carbon nitride

Conditions

Conditions	Yield
by heating in sealed tube at 300°C;
by heating in sealed tube at 300°C;

...Expand

: calcium cyanide

: 7733-02-0
zinc(II) sulfate

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
pptn.;;
pptn.;;

: 10196-18-6
zinc(II) nitrate

: calcium cyanide

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
pptn.;;
pptn.;;

: calcium cyanide

: 7646-85-7
zinc(II) chloride

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
pptn.;;
pptn.;;

: 74-90-8
hydrogen cyanide

: zinc(II) oxide

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In water passing HCN into a sludge of ZnO;;
In water passing HCN into a sludge of ZnO;;

: 74-90-8
hydrogen cyanide

: zinc(II) hydroxide

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In acetic acid on pptg. of soln. of Zn(OH)2 in acetic acid with HCN and drying at 110°C;;

: 74-90-8
hydrogen cyanide

: 7733-02-0
zinc(II) sulfate

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
With KOC(O)CH3 In water passing HCN into an aq. soln. of ZnSO4 and K acetate;;
With KOC(O)CH3 In water passing HCN into an aq. soln. of ZnSO4 and K acetate;;

: 74-90-8
hydrogen cyanide

: 557-34-6
zinc diacetate

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In methanol; diethyl ether on mixing of soln. of Zn acetate/methanol and HCN/ether;; on drying ppt. at 75°C, then in vacuum over P2O5;;
In water passing HCN into an aq. soln. of Zn acetate; pptn. is incomplete;; pptn.;;
In water stratifying of aq. Zn acetate with aq. HCN;; pptn.;;

: zinc(II) nitrate hexahydrate

: dipotassium tetracyanozincate(II)

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In water layering water on aq. soln. of zinc compds., slow diffusion for 2-3 wk; filtration, washing with water, ethanol, air drying;

: potassium cyanide

: zinc(II) oxide

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
digestion or boiling a sludge of ZnO and a moderately concd. KCN soln.;;
digestion or boiling a sludge of ZnO and a moderately concd. KCN soln.;;

: 57-13-6
urea

: 7440-66-6
zinc

: 557-21-1
zinc(II) cyanide

: zinc potassium cyanide

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In water Electrolysis; electolysis of an aq. soln. of Zn(CN)2*2KCN (no excess of KCN);; anodic pptn. of Zn(CN)2;;

: 592-04-1
mercury(II) cyanide

: 7440-66-6
zinc

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In ammonia
In ammonia NH3 (liquid);

: 420-05-3
cyanic acid

: 7440-66-6
zinc

: 557-21-1
zinc(II) cyanide

: potassium cyanide

: 7440-66-6
zinc

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In not given Electrolysis; Zn(CN)2 formed as layer on Zn anode in KCN soln.;;
In not given Electrolysis; electrolysis of a 4 n KCN soln. with Zn electrodes using a current density of 4.61 A*m^-2; formation on the anode;;

: 506-78-5
cyanogen iodide

: 557-20-0
diethylzinc

A: 557-21-1
zinc(II) cyanide

B: 75-03-6
ethyl iodide

...Expand

: 773837-37-9
sodium cyanide

: 7733-02-0
zinc(II) sulfate

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
pptn.;;
pptn.;;

: 773837-37-9
sodium cyanide

: zinc(II) sulfate heptahydrate

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In water (The Chem. of Cyano Complexes of the Transition Elements, Academic Press: London, 1976, p. 287); aq. soln. of NaCN was stirred into aq. soln. ofZn compd.; filtered; washed (water); washed (acetone); dried (vac.);

: 71680-52-9, 130166-69-7
ammonium cyanide

: 7733-02-0
zinc(II) sulfate

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
pptn.;;
pptn.;;

: potassium cyanide

: 7733-02-0
zinc(II) sulfate

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
slow addn. of a moderately concd. soln. of KCN to a soln. of ZnSO4 until the end of pptn.;; washing of the pptn. with water; drying with alc. and diethyl ether;;
slow addn. of a moderately concd. soln. of KCN to a soln. of ZnSO4 until the end of pptn.;; washing of the pptn. with water; drying with alc. and diethyl ether;;

: thallium(I) zinc cyanide

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
In water strong acids;; pptn.;;

: 10196-18-6
zinc(II) nitrate

: 71680-52-9, 130166-69-7
ammonium cyanide

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
pptn.;;
pptn.;;

: 71680-52-9, 130166-69-7
ammonium cyanide

: 7646-85-7
zinc(II) chloride

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
pptn.;;
pptn.;;

: mercury(II) cyanide

: 557-21-1
zinc(II) cyanide

Conditions

Conditions	Yield
With zinc ambient temp., CO2 stream;
With Zn ambient temp., CO2 stream;

: mercury(II) cyanide

A: 557-21-1
zinc(II) cyanide

B: mercury

Conditions

Conditions	Yield
With zinc In ammonia fast reaction;
With Zn In ammonia NH3 (liquid); fast reaction;

: 557-21-1
zinc(II) cyanide

: 66107-30-0
4-bromophenyl trifluoromethanesulfonate

: 623-00-7
4-bromobenzenecarbonitrile

Conditions

Conditions	Yield
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride	100%

: 557-21-1
zinc(II) cyanide

: 66107-30-0
4-bromophenyl trifluoromethanesulfonate

: 106-38-7
para-bromotoluene

Conditions

Conditions	Yield
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride	100%

: 557-21-1
zinc(II) cyanide

: 14001-66-2
5-bromo-2-methoxypyrimidine

: 38373-47-6
2-methoxypyrimidine-5-carbonitrile

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 115℃; for 3h; Sealed tube;	100%
tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 85℃; Inert atmosphere;

: 557-21-1
zinc(II) cyanide

: 1307213-09-7
(S)-7-bromo-1,2,3,4-tetrahydro-cyclopenta[b]indol-2-ylamine (R)-2-hydroxy-3-phenylpropionic acid salt

: 1029691-23-3
(S)-(7-cyano-1,2,3,4-tetrahydrocyclopenta[b]indol-2-yl)carbamic acid isopropyl ester

Conditions

Conditions	Yield
With zinc(II) formate; zinc; 1,1'-bis-(diphenylphosphino)ferrocene; palladium In ISOPROPYLAMIDE at 110℃; Product distribution / selectivity; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: 1303517-13-6
(4a-R,9a-S)-trifluoro-methanesulfonic acid 1-(2,2,2-trifluoro-acetyl)-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridin-6-yl ester

: 1303517-15-8
(4a-R,9a-S)-1-(2,2,2-trifluoro-acetyl)-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile

Conditions

Conditions	Yield
1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl-formamide at 80℃; for 12h; Inert atmosphere;	100%
(diphenylphosphin)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl-formamide at 80℃; for 12h;	100%

: 557-21-1
zinc(II) cyanide

: 1313279-89-8
(R)-tert-butyl 3-(6-chloro-2-(6-fluoroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-ylamino)piperidine-1-carboxylate

: 1313280-19-1
(R)-tert-butyl 3-(6-cyano-2-(6-fluoroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-ylamino)piperidine-1-carboxylate

Conditions

Conditions	Yield
tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 130℃; for 1h; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: 1323076-87-4
10a-(4-bromophenyl)-2,3,10,10a-tetrahydro-1H,5H-imidazo[1,2-a]pyrrolo[1,2-d]pyrazin-5-one

: 1323076-92-1
4-(5-oxo-2,3-dihydro-1H,5H-imidazo[1,2-a]pyrrolo[1,2-d]pyrazin-10a(10H)-yl)benzonitrile

Conditions

Conditions	Yield
tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 150 - 160℃; for 0.666667h; Inert atmosphere; Microwave irradiation; Sealed tube;	100%

: 557-21-1
zinc(II) cyanide

: 1394909-96-6
4-[3-bromo-4-(2,6-dimethyl-4-pyridinyl)-2,5-difluorophenyl]-2,6-dimethyl-(2R,6S)-morpholine

: 1394909-97-7
3-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-6-(2,6-dimethyl-4-pyridinyl)-2,5-difluoro-benzonitrile

Conditions

Conditions	Yield
With triphenylphosphine; tetrakis(triphenylphosphine) palladium(0) In acetonitrile at 150℃; for 18h; Microwave irradiation;	100%

: 557-21-1
zinc(II) cyanide

: 26163-03-1
2-amino-3-bromo-5-chloropyridine

: 869557-28-8
2-amino-5-chloropyridine-3-carbonitrile

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In 1-methyl-pyrrolidin-2-one at 110℃; for 5h; Further stages;	100%
With tetrakis(triphenylphosphine) palladium(0) at 110 - 120℃; for 5h;	100%

: 557-21-1
zinc(II) cyanide

: (6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)((3aR,5R,6aS)-5-(2-(trifluoromethyl)phenyl)hexahydrocyclopenta[c]pyrrole-2(1H)-yl)methanone

: 3-((3aR,5R,6aS)-5-(2-(trifluoromethyl)phenyl)octahydrocyclopenta[c]pyrrole-2-carbonyl)-[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrile

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 130℃; for 0.5h; Microwave irradiation;	100%
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 130℃; for 0.5h; Microwave irradiation; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: (6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-((3aR,6aS)-5-(2-(trifluoromethyl)phenyl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)methanone

: 3-((3aR,6aS)-5-(2-(trifluoromethyl)phenyl)octahydrocyclopenta[c]pyrrole-2-carbonyl)[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrile

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 130℃; for 0.5h; Microwave irradiation;	100%

: 557-21-1
zinc(II) cyanide

: C17H13IN4O2

: C18H13N5O2

Conditions

Conditions	Yield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; zinc In N,N-dimethyl-formamide at 145℃; for 2.5h; Solvent; Temperature; Microwave irradiation;	100%

: 557-21-1
zinc(II) cyanide

: 4’-(3-bromo-5-fluoro-phenoxy)-7’-methylsulfonyl-spiro[1,3-dioxolane-2,1’-indane]

: 3-fluoro-5-(7’-methylsulfonylspiro[1,3-dioxolane-2,1’-indane]-4’-yl)oxy-benzonitrile

Conditions

Conditions	Yield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; zinc In N,N-dimethyl-formamide at 110℃; for 2h; Inert atmosphere;	100%
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; zinc In N,N-dimethyl-formamide at 110℃; for 2h; Inert atmosphere;	100%
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; zinc In N,N-dimethyl-formamide at 110℃; for 2h; Inert atmosphere;	100%
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; zinc In N,N-dimethyl-formamide at 110℃; for 2h; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: (4-aminophenyl)(4-(5-chloro-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidin-2-ylamino)piperidin-1-yl)methanone

: 2-(1-(4-aminobenzoyl)piperidin-4-ylamino )-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidine-5-carbonitrile

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); zinc; XPhos at 95℃; for 2h; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: (4-aminophenyl)((R)-3-(5-chloro-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidin-2-ylamino)pyrrolidin-1-yl)methanone

: 2-((R)-1-(4-aminobenzoyl)pyrrolidin-3-ylamino)-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidine-5-carbonitrile

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); zinc; XPhos at 95℃; for 1.5h; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: 864773-66-0
5-bromo-6-fluoro-3-methyl-1H-indazole

: 6-fluoro-3-methyl-1H-indazole-5-carbonitrile

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 100℃; for 16h; Inert atmosphere;	100%
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl-formamide at 120℃; for 4h; Inert atmosphere;
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl-formamide at 120℃; for 4h; Inert atmosphere;

: 557-21-1
zinc(II) cyanide

: tert-butyl 4-(4-bromophenylamino)-4-methylpiperidine-1-carboxylate

: tert-butyl 4-(4-cyanophenylamino)-4-methylpiperidine-1-carboxylate

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In N,N-dimethyl-formamide at 130℃; for 1h; Inert atmosphere; Microwave irradiation;	100%

: 557-21-1
zinc(II) cyanide

: 1581753-62-9
6-bromo-1-cyclopropyl-3,3-dimethyl-1,3-dihydroindol-2-one

: 1-cyclopropyl-3,3-dimethyl-2-oxoindoline-6-carbonitrile

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 85℃; for 16h; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: (4S,6S)-4-(5-amino-2-fluoro-4-iodophenyl)-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-2-amine

: 2-amino-4-((4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl)-5-fluorobenzonitrile

Conditions

Conditions	Yield
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); zinc In N,N-dimethyl-formamide at 110℃; Sealed tube; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: 59489-71-3
5-amino-2-bromopyrazine

: 113305-94-5
2-amino-5-cyanopyrazine

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); N,N,N,N,-tetramethylethylenediamine; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene at 100℃; for 2h;	100%

: 557-21-1
zinc(II) cyanide

: tert-butyl N-[(4-bromo-2,6-difluorophenyl)methyl]carbamate

: 633336-82-0
tert-butyl N-[(4-cyano-2,6-difluorophenyl)methyl]carbamate

Conditions

Conditions	Yield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 1,1'-bis-(diphenylphosphino)ferrocene In water; N,N-dimethyl-formamide at 120℃; for 1h;	100%

: 557-21-1
zinc(II) cyanide

: 1208110-27-3
C24H26F3NO4S

: 1208110-34-2
(2RS)-1'-[2-(2-methylphenyl)ethyl]-1-oxo-3,4-dihydro-1H-spiro[naphthalene-2,2'-piperidine]-6-carbonitrile hydrochloride

Conditions

Conditions	Yield
Stage #1: zinc(II) cyanide; C24H26F3NO4S With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl-formamide at 120℃; for 1.5h; Inert atmosphere; Stage #2: With hydrogenchloride In diethyl ether; water; ethyl acetate Cooling with ice;	100%

: 557-21-1
zinc(II) cyanide

: 2-chloro-3-hydrazinyl-5-(trifluoromethoxy)pyridine

: 6-(trifluoromethoxy)-1H-pyrazolo[4,3-b]pyridine-3-amine

Conditions

Conditions	Yield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; zinc In N,N-dimethyl-formamide at 120℃; for 0.5h; Reagent/catalyst; Inert atmosphere;	100%

: 891785-28-7
6-bromo-isoquinolin-3-ylamine

: 557-21-1
zinc(II) cyanide

: 3-aminoisoquinoline-6-carbonitrile

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl acetamide at 90℃; for 1h;	100%
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl acetamide at 90℃; for 1h;	0.57 g
With tetrakis(triphenylphosphine) palladium(0); zinc In N,N-dimethyl-formamide at 80℃;

: 557-21-1
zinc(II) cyanide

: rac-(4bS,5R,6S,7S,7aR)-7a-(4-bromophenyl)-4-methoxy-7-phenyl-6-(piperidin-1-ylmethyl)-5,6,7,7a-tetrahydro-4bH-cyclopenta[4,5]furo[2,3-c]pyridine-4b,5-diol

: rac-4-((4bS,5R,6S,7S,7aR)-4b,5-dihydroxy-4-methoxy-7-phenyl-6-(piperidin-1-ylmethyl)-4b,5,6,7-tetrahydro-7aH-cyclopenta[4,5]furo[2,3-c]pyridin-7a-yl)benzonitrile

Conditions

Conditions	Yield
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); zinc In N,N-dimethyl-formamide at 140℃; for 2.5h; Inert atmosphere;	100%
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); zinc In N,N-dimethyl-formamide at 140℃; for 2.5h; Inert atmosphere;	82%

: 557-21-1
zinc(II) cyanide

: 5-bromo-6-fluoro-3-(4-phenoxyphenyl)-1H-indazole

: 6-fluoro-3-(4-phenoxyphenyl)-1H-indazole-5-carbonitrile

Conditions

Conditions	Yield
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl-formamide at 100℃; for 4h;	100%
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl-formamide at 100℃; for 4h; Inert atmosphere;	74%

: 557-21-1
zinc(II) cyanide

: 220513-46-2
6-bromo-8-fluoro-quinoline

: 8-fluoroquinoline-6-carbonitrile

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 100℃; for 3h; Inert atmosphere;	100%
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl-formamide at 130℃; Inert atmosphere;	74.1%
With tris-(dibenzylideneacetone)dipalladium(0); XPhos In water; N,N-dimethyl-formamide at 150℃; for 1h; Microwave irradiation;	65.6%

: 557-21-1
zinc(II) cyanide

: (S)-tert-butyl 3-((5-iodo-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)piperidine-1-carboxylate

: (S)-tert-butyl-3-((5-cyano-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)piperidine-1-carboxylate

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); zinc; XPhos In N,N-dimethyl acetamide at 95℃; for 18h;	100%

: 557-21-1
zinc(II) cyanide

: C37H30BrF2N3OS

: C38H30F2N4OS

Conditions

Conditions	Yield
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); zinc In N,N-dimethyl acetamide at 150℃; for 4h; Inert atmosphere;	100%
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); zinc In N,N-dimethyl acetamide at 150℃; for 4h; Inert atmosphere;	100%

: 557-21-1
zinc(II) cyanide

: C37H31BrFN3OS

: C38H31FN4OS

Conditions

Conditions	Yield
With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); zinc In N,N-dimethyl acetamide at 120℃; for 12h; Inert atmosphere;	100%

Zinc cyanide Consensus Reports

Zinc and its compounds, as well as cyanide and its compounds, are on the Community Right-To-Know List. Reported in EPA TSCA Inventory.

Zinc cyanide Standards and Recommendations

DOT Classification: 6.1; Label: Poison
OSHA PEL: TWA 5 mg(CN)/m³
ACGIH TLV: CL 5 mg(CN)/m³ (skin)
DFG MAK: 5 mg/m³
NIOSH REL: (Cyanide) CL 5 mg(CN)/m³/10M

Zinc cyanide Specification

This chemical is called Zinc cyanide, and its IUPAC name is zinc dicyanide. With the molecular formula of C₂N₂Zn, its classification codes are Agricultural Chemical; Experimental pesticide; Unspecified / Unclassified pesticide. The CAS registry number of this chemical is 557-21-1. Additionally, its product categories are Inorganics; Zinc Salts; Metal and Ceramic Science; Salts. Moreover, it's insoluble in cold water, hydrocyanic acid, ethanol, ether and organic acids, slightly soluble in water, soluble in caustic soda, ammonia, acetic acid zinc solution.

Other characteristics of the Zinc cyanide can be summarised as followings: (1)ACD/LogP: -0.25; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.25; (4)ACD/LogD (pH 7.4): -0.25; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 17.42; (8)ACD/KOC (pH 7.4): 17.42; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 23.79 Å²; (13)Enthalpy of Vaporization: 27.18 kJ/mol; (14)Boiling Point: 25.7 °C at 760 mmHg; (15)Vapour Pressure: 740 mmHg at 25°C.

The Zinc cyanide could be obtained by the reactants of serum zinc chloride and sodium cyanide solution. This reaction needs the processes of separation and drying. The reaction equation is as following: 2NaCN+ZnC1₂→Zn(CN)₂+2NaCl.

Uses of this chemical: The Zinc cyanide is mainly used in electroplating, organic synthesis, medicine and pesticide manufacturing. It could react with 1,3,5-triethyl-benzene to obtain the 2,4,6-triethyl-benzaldehyde. This reaction needs the reagent of HCl , and the yield is about 79 %.

Zinc cyanide could react with 1,3,5-triethyl-benzene to obtain the 2,4,6-triethyl-benzaldehyde

When you are using this chemical, please be cautious about it as the following: This chemical is very toxic by inhalation, in contacting with skin and if swallowed. It's also very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. If contacts with acid, it will liberate very toxic gas. Keep its container tightly closed. Do not empty into drains. Refer to special instructions / safety data sheets if you use it. After contacting with skin, wash immediately with plenty of soap-suds. Moreover, this material and its container must be disposed of as hazardous waste.

You can still convert the following datas into molecular structure:
1.SMILES: [Zn+2].[C-]#N.[C-]#N
2.InChI: InChI=1/2CN.Zn/c2*1-2;/q2*-1;+2
3.InChIKey: GTLDTDOJJJZVBW-UHFFFAOYAM

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
rat	LCLo	inhalation	61mg/m³/4H (61mg/m³)	National Technical Information Service. Vol. OTS0571244,
rat	LD50	oral	54mg/kg (54mg/kg)	Toxicologist. Vol. 3, Pg. 170, 1983.
rat	LDLo	intraperitoneal	100mg/kg (100mg/kg)	National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 28, 1953.

Product Name

ZINC CYANIDE

Synthetic route

Zinc cyanide Consensus Reports

Zinc cyanide Standards and Recommendations

Zinc cyanide Specification

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