-
Name
Zorubicin
- EINECS 253-076-4
- CAS No. 54083-22-6
- Density 1.54g/cm3
- Solubility
- Melting Point
- Formula C34H35 N3 O10
- Boiling Point °Cat760mmHg
- Molecular Weight 645.6558
- Flash Point °C
- Transport Information
- Appearance White or almost white crystalline powder
- Safety
- Risk Codes
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Molecular Structure
- Hazard Symbols
- Synonyms Benzoicacid, [1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide(9CI); Benzoic acid, [1-[4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide,(2S-cis)-; Daunomycin benzoylhydrazone; MCMC 4222; Rubidazon; Rubidazone;Zorubicin
- PSA 210.23000
- LogP 3.33700
Zorubicin Chemical Properties
IUPAC Name: N-[(E)-1-[(2S,4S)-4-(4-Amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]benzamide
Synonyms: (2S-cis)-Benzoic Acid [1-[4-[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-napthacenyl]ethylidene]hydrazide ; Benzoic Acid Hydrazide 3-Hydrazone with Daunorubicin ; Benzoic acid, [(1E)-1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide ; Benzoic acid, 2-[(1E)-1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide
CAS NO: 54083-22-6
Molecular Formula of Rubidazone (CAS NO.54083-22-6) : C34H35N3O10
Molecular Weight of Rubidazone (CAS NO.54083-22-6) : 645.66
Molecular Structure of Rubidazone (CAS NO.54083-22-6) : 
Index of Refraction: 1.705
Surface Tension: 62.9 dyne/cm
Density: 1.54 g/cm3
Zorubicin Uses
Rubidazone (benzoylhydrazone daunorubicin) is a semisynthetic compound with a good experimental antitumor activity. Its main interest is its lower toxicity and cardiotoxicity. In human chemotherapy, it is considered a valuable drug.
Zorubicin Toxicity Data With Reference
| 1. | mmo-sat 10 µg/plate | EJCODS European Journal of Cancer and Clinical Oncology. 19 (1983),641. | ||
| 2. | dni-hmn:oth 500 µg/L | CCPHDZ Cancer Chemotherapy and Pharmacology. 2 (1979),31. |
Zorubicin Safety Profile
Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also RUBIDAZONE MONOHYDROCHLORIDE.
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