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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Ethyl-2-vinylpyridine Manufacturer/High quality/Best price/In stock

Cas:5408-74-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:10 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Pyridine,2-ethenyl-5-ethyl-

Cas:5408-74-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pyridine,2-ethenyl-5-ethyl-

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pyridine,2-ethenyl-5-ethyl-

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality moderate price &quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used to make other chemica

Pyridine,2-ethenyl-5-ethyl-

Cas:5408-74-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

5-ETHYL-2-VINYL PYRIDINE; PYRIDINE, 2-ETHENYL-5-ETHYL-; 3-ethyl-6-vinylpyridine; 5-ethyl-2-vinyl-pyridin; 2-Vinyl-5-ethylpyridine; 2-ethenyl- 5-ethylpyridine; 2-ethenyl-5-ethyl-pyridine; NSC 8395 CAS No.: 5408-74-2 Molecular formula: C9H11N M

5-ETHYL-2-VINYL PYRIDINE

Cas:5408-74-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Pyridine,2-ethenyl-5-ethyl-

Cas:5408-74-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

5-ETHYL-2-VINYL PYRIDINE

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

hight degree of purity Application:Fine chemical intermediates, used as the main raw material for he synthesis of various pesticides, medicines, surfactants, polymer monomers, Ond Ontifungal agents

Pyridine,2-ethenyl-5-ethyl-

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

5-Ethyl-2-vinylpyridine cas 5408-74-2Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

5-Ethyl-2-vinylpyridine cas 5408-74-2

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Other

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-ETHYL-2-VINYL PYRIDINE

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

2-Ethenyl-5-ethyl-pyridine

Cas:5408-74-2

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

5-Ethyl-2-vinyl pyridine

Cas:5408-74-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

ENAO Chemical Co, Limited

For quick quotation, please send us the inquiry include CAS#, Structure, Chemical Name, quantity, purity, as well as any additional specifications you require, we will try to get back to you within 24 hours. Our Services Besides manufacturing,

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

5-ETHYL-2-VINYL PYRIDINE

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Other

inquiry

Capot Chemical Co., Ltd.

At Capot,We can synthesize and purify your complex molecules from 100 gram to 10 tons.Appearance:Clear colorless to light yellow liquid Storage:Dry,Seal and Cool place Package:1G,5G,10G,25G,100G,250G,500G,1KG,5KG,10KG,25KG,50KG,100KG,150KG,200KG. App

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai AngewChem Co., Ltd.

Shanghai AngewChemCo., Ltd. is an innovative enterprise on fine chemicals and pharmaceuticals. Based on Shanghai R&D center and Hunan chemical manufacturing plant, we offer chemical research, process development, and large-scale production. Complete

5-ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 5-Ethyl-2-vinylpyridine, CAS:5408-74-2 with the most competitive price and the best q

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuxi Morality Chemical Co., Ltd

Do best quality products, erect the morality model Application:please email us, thanks

5-Ethyl-2-vinyl pyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Other

inquiry

Debye Scientific

Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Chemwish Technology Co., Ltd

High quality Products with prompt deliveryAppearance:Yellow Oil Package:based on customer requirement Application:organic intermediates Transportation:By air of By sea Port:any port of China

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beyond Pharmaceutical Co., Ltd

5-Ethyl-2-vinyl pyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

yuyongmei

YUYONGMEI was established in Aug,1999, located in the industrial park of Nanjing University of Technology, It is a private enterprises in Jiangsu Province with 1200 square meters’ R&D center. Our R&D center has a well-equipped synthetic laboratory a

Pyridine,2-ethenyl-5-ethyl-

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Lonza Japan Ltd.

5-ETHYL-2-VINYL PYRIDINE

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Aconpharm Corporation

5-Ethyl-2-vinylpyridine

Cas:5408-74-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

5-{4-[2-chloro-2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidene dione
646519-88-2

5-{4-[2-chloro-2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidene dione

A

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

B

Pioglitazone
105355-27-9

Pioglitazone

C

5-(4-hydroxybenzyl)-2,4-thiazolidinedione
74772-78-4

5-(4-hydroxybenzyl)-2,4-thiazolidinedione

Conditions
ConditionsYield
With acetic acid; zinc In ethyl acetate at 25 - 35℃; for 9h; Product distribution / selectivity;A n/a
B 41%
C n/a
With acetic acid; zinc at 25 - 30℃; for 15h;A 10%
B 25%
C 12%
Stage #1: 5-{4-[2-chloro-2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidene dione With acetic acid; zinc at 5 - 30℃; for 15h;
Stage #2: With sodium carbonate In water; acetic acid Product distribution / selectivity;
A 10%
B 20%
C 12%
5-ethyl-2-methyl-pyridine
104-90-5

5-ethyl-2-methyl-pyridine

formaldehyd
50-00-0

formaldehyd

A

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

B

5-ethyl-2-(2-hydroxyethyl)pyridine
5223-06-3

5-ethyl-2-(2-hydroxyethyl)pyridine

Conditions
ConditionsYield
With dipotassium peroxodisulfate; ethanol at 220℃;
In water at 155℃; under 4500.45 Torr; for 4h; Pressure; Autoclave;A n/a
B 70 g
5-ethyl-2-(2-hydroxyethyl)pyridine
5223-06-3

5-ethyl-2-(2-hydroxyethyl)pyridine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
With aluminum oxide at 420℃;
With potassium hydroxide at 175℃; Erhitzen unter vermindertem Druck;
With potassium hydroxide Heating; Yield given;
hydrogenchloride
7647-01-0

hydrogenchloride

5-ethyl-2-(2-hydroxyethyl)pyridine
5223-06-3

5-ethyl-2-(2-hydroxyethyl)pyridine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
at 160 - 170℃; nachfolgenden Erwaermen mit Natronlauge;
5-ethyl-2-<β-oxy-ethyl>-pyridine

5-ethyl-2-<β-oxy-ethyl>-pyridine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
With hydrogenchloride at 160 - 170℃; im Rohr; Erwaermen mit Natronlauge;
With hydrogenchloride at 160 - 170℃; im Rohr; Destillieren ueber Kaliumhydroxyd;
5-ethyl-2-(2-hydroxyethyl)pyridine
5223-06-3

5-ethyl-2-(2-hydroxyethyl)pyridine

potassium hydroxide

potassium hydroxide

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Destillation;
5-ethyl-2-methyl-pyridine
104-90-5

5-ethyl-2-methyl-pyridine

pyridine-homologous/ues

pyridine-homologous/ues

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: formic acid, tert-butylcatechol / ethanol / 120 h / Heating
2: KOH / Heating
View Scheme
5-ethyl-2-methyl-pyridine
104-90-5

5-ethyl-2-methyl-pyridine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium peroxo disulfate; ethanol / 220 °C
2: potassium hydroxide / 175 °C / Erhitzen unter vermindertem Druck
View Scheme
Multi-step reaction with 2 steps
1: formic acid; water / 240 °C / 139011 Torr
2: potassium hydroxide / 175 °C / Erhitzen unter vermindertem Druck
View Scheme
Multi-step reaction with 3 steps
1: water / 3 h / 150 - 160 °C / 3750.38 - 4500.45 Torr / Autoclave
2: triethylamine; p-toluenesulfonyl chloride / toluene / 0 - 5 °C
3: potassium carbonate / toluene / 10 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1: water / 4 h / 155 °C / 4500.45 Torr / Autoclave
2: triethylamine; p-toluenesulfonyl chloride / toluene / 0 - 5 °C
3: potassium carbonate / toluene / 10 h / Reflux
View Scheme
5-{4-[2-chloro-2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidene dione hydrochloride
646519-89-3

5-{4-[2-chloro-2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidene dione hydrochloride

A

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

B

Pioglitazone
105355-27-9

Pioglitazone

C

5-(4-hydroxybenzyl)-2,4-thiazolidinedione
74772-78-4

5-(4-hydroxybenzyl)-2,4-thiazolidinedione

Conditions
ConditionsYield
With acetic acid; zinc In methanol Product distribution / selectivity; Industry scale;
2-hydroxymethyl-5-ethyl pyridine
768-61-6

2-hydroxymethyl-5-ethyl pyridine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
With potassium hydroxide
5-{4-[2-chloro-2-(5-ethylpyridn-2-yl)ethoxy]benzylidene}-2,4-thiazolidene dione
646519-94-0

5-{4-[2-chloro-2-(5-ethylpyridn-2-yl)ethoxy]benzylidene}-2,4-thiazolidene dione

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogen / tetrahydrofuran / 12 h
2: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
2-(5-ethyl-1-oxypyridin-2-yl)ethanol
90643-32-6

2-(5-ethyl-1-oxypyridin-2-yl)ethanol

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 0.5 h / 120 °C
2: sodium hydroxide / water / 2 h / 40 °C
3: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
4: N,N-dimethyl-formamide / 14 h / 80 °C
5: thionyl chloride / chloroform / 1 h / Reflux
6: acetic acid; piperidine / toluene / Heating
7: hydrogen / tetrahydrofuran / 12 h
8: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 8 steps
1: 0.5 h / 120 °C
2: sodium hydroxide / water / 2 h / 40 °C
3: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
4: N,N-dimethyl-formamide / 14 h / 80 °C
5: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
6: thionyl chloride / chloroform / 3 h / Reflux
7: hydrogen / tetrahydrofuran / 12 h
8: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 8 steps
1: 0.5 h / 120 °C
2: sodium hydroxide / water / 2 h / 40 °C
3: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
4: N,N-dimethyl-formamide / 14 h / 80 °C
5: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
6: sodium tetrahydroborate; butane-2,3-dione dioxime; cobalt(II) chloride hexahydrate / water; N,N-dimethyl-formamide / 4 h / 65 - 85 °C / Large scale
7: thionyl chloride / chloroform / 2 h / Reflux
8: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
1-(5-ethylpyridin-2-yl)ethan-1,2-diol

1-(5-ethylpyridin-2-yl)ethan-1,2-diol

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
2: N,N-dimethyl-formamide / 14 h / 80 °C
3: thionyl chloride / chloroform / 1 h / Reflux
4: acetic acid; piperidine / toluene / Heating
5: hydrogen / tetrahydrofuran / 12 h
6: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 6 steps
1: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
2: N,N-dimethyl-formamide / 14 h / 80 °C
3: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
4: sodium tetrahydroborate; butane-2,3-dione dioxime; cobalt(II) chloride hexahydrate / water; N,N-dimethyl-formamide / 4 h / 65 - 85 °C / Large scale
5: thionyl chloride / chloroform / 2 h / Reflux
6: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 6 steps
1: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
2: N,N-dimethyl-formamide / 14 h / 80 °C
3: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
4: thionyl chloride / chloroform / 3 h / Reflux
5: hydrogen / tetrahydrofuran / 12 h
6: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
5-ethyl-2-[2-oxo-(1,3,2)dioxathiolan-4-yl]pyridine

5-ethyl-2-[2-oxo-(1,3,2)dioxathiolan-4-yl]pyridine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: N,N-dimethyl-formamide / 14 h / 80 °C
2: thionyl chloride / chloroform / 1 h / Reflux
3: acetic acid; piperidine / toluene / Heating
4: hydrogen / tetrahydrofuran / 12 h
5: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 5 steps
1: N,N-dimethyl-formamide / 14 h / 80 °C
2: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
3: sodium tetrahydroborate; butane-2,3-dione dioxime; cobalt(II) chloride hexahydrate / water; N,N-dimethyl-formamide / 4 h / 65 - 85 °C / Large scale
4: thionyl chloride / chloroform / 2 h / Reflux
5: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 5 steps
1: N,N-dimethyl-formamide / 14 h / 80 °C
2: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
3: thionyl chloride / chloroform / 3 h / Reflux
4: hydrogen / tetrahydrofuran / 12 h
5: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
4-[2-chloro-2-(5-ethyl-2-pyridyl)ethoxy]benzaldehyde

4-[2-chloro-2-(5-ethyl-2-pyridyl)ethoxy]benzaldehyde

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid; piperidine / toluene / Heating
2: hydrogen / tetrahydrofuran / 12 h
3: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzaldehyde
471295-98-4

4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzaldehyde

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: thionyl chloride / chloroform / 1 h / Reflux
2: acetic acid; piperidine / toluene / Heating
3: hydrogen / tetrahydrofuran / 12 h
4: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 4 steps
1: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
2: thionyl chloride / chloroform / 3 h / Reflux
3: hydrogen / tetrahydrofuran / 12 h
4: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 4 steps
1: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
2: sodium tetrahydroborate; butane-2,3-dione dioxime; cobalt(II) chloride hexahydrate / water; N,N-dimethyl-formamide / 4 h / 65 - 85 °C / Large scale
3: thionyl chloride / chloroform / 2 h / Reflux
4: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
acetic acid 2-acetoxy-2-(5-ethyl-1-pyridin-2-yl)ethyl ester

acetic acid 2-acetoxy-2-(5-ethyl-1-pyridin-2-yl)ethyl ester

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: sodium hydroxide / water / 2 h / 40 °C
2: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
3: N,N-dimethyl-formamide / 14 h / 80 °C
4: thionyl chloride / chloroform / 1 h / Reflux
5: acetic acid; piperidine / toluene / Heating
6: hydrogen / tetrahydrofuran / 12 h
7: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 7 steps
1: sodium hydroxide / water / 2 h / 40 °C
2: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
3: N,N-dimethyl-formamide / 14 h / 80 °C
4: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
5: thionyl chloride / chloroform / 3 h / Reflux
6: hydrogen / tetrahydrofuran / 12 h
7: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 7 steps
1: sodium hydroxide / water / 2 h / 40 °C
2: thionyl chloride; triethylamine / dichloromethane / 1.25 h / 0 - 5 °C
3: N,N-dimethyl-formamide / 14 h / 80 °C
4: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
5: sodium tetrahydroborate; butane-2,3-dione dioxime; cobalt(II) chloride hexahydrate / water; N,N-dimethyl-formamide / 4 h / 65 - 85 °C / Large scale
6: thionyl chloride / chloroform / 2 h / Reflux
7: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
5-{4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzylidene}-2,4-thiazolidene dione
646519-84-8

5-{4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzylidene}-2,4-thiazolidene dione

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: thionyl chloride / chloroform / 3 h / Reflux
2: hydrogen / tetrahydrofuran / 12 h
3: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium tetrahydroborate; butane-2,3-dione dioxime; cobalt(II) chloride hexahydrate / water; N,N-dimethyl-formamide / 4 h / 65 - 85 °C / Large scale
2: thionyl chloride / chloroform / 2 h / Reflux
3: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
2-bromo-1-(5-ethylpyridin-2-yl)ethanol
646519-81-5

2-bromo-1-(5-ethylpyridin-2-yl)ethanol

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium carbonate / tert-butyl alcohol / 1.17 h / Reflux
1.2: 11 h / Reflux
2.1: thionyl chloride / chloroform / 1 h / Reflux
3.1: acetic acid; piperidine / toluene / Heating
4.1: hydrogen / tetrahydrofuran / 12 h
5.1: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate / tert-butyl alcohol / 1.17 h / Reflux
1.2: 11 h / Reflux
2.1: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
3.1: thionyl chloride / chloroform / 3 h / Reflux
4.1: hydrogen / tetrahydrofuran / 12 h
5.1: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate / tert-butyl alcohol / 1.17 h / Reflux
1.2: 11 h / Reflux
2.1: pyrrolidine / methanol / 2 h / 50 - 55 °C / Large scale
3.1: sodium tetrahydroborate; butane-2,3-dione dioxime; cobalt(II) chloride hexahydrate / water; N,N-dimethyl-formamide / 4 h / 65 - 85 °C / Large scale
4.1: thionyl chloride / chloroform / 2 h / Reflux
5.1: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
5-{4-[2-(5-ethyl-pyridin-2-yl)-2-hydroxyethoxy]benzyl}-2,4-thiazolidinedione
101931-00-4

5-{4-[2-(5-ethyl-pyridin-2-yl)-2-hydroxyethoxy]benzyl}-2,4-thiazolidinedione

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thionyl chloride / chloroform / 2 h / Reflux
2: zinc; acetic acid / 15 h / 25 - 30 °C
View Scheme
toluene-4-sulfonic acid 2-(5-ethylpyridin-2-yl)ethyl ester
144809-27-8

toluene-4-sulfonic acid 2-(5-ethylpyridin-2-yl)ethyl ester

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Conditions
ConditionsYield
With potassium carbonate In toluene for 10h; Reflux;
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

4-aminotiophenol
1193-02-8

4-aminotiophenol

4-[2-(5-Ethyl-pyridin-2-yl)-ethylsulfanyl]-phenylamine
136401-93-9

4-[2-(5-Ethyl-pyridin-2-yl)-ethylsulfanyl]-phenylamine

Conditions
ConditionsYield
Ambient temperature;95%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

2-bromo-1-(5-ethylpyridin-2-yl)ethanol
646519-81-5

2-bromo-1-(5-ethylpyridin-2-yl)ethanol

Conditions
ConditionsYield
With N-Bromosuccinimide; water In tert-butyl alcohol at 25 - 30℃; for 1.16667h; Reagent/catalyst; Solvent; Temperature; Time;95%
With water; bromine; potassium bromide at 60 - 65℃; for 0.666667h; Product distribution / selectivity;86%
With N-Bromosuccinimide; water In 1,4-dioxane at 25 - 30℃; for 4h; Product distribution / selectivity;85%
With N-Bromosuccinimide; water In tetrahydrofuran at 25 - 30℃; for 4h; Product distribution / selectivity;82%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

A

1-(5-ethyl-2-pyridinyl)ethanone
286411-85-6

1-(5-ethyl-2-pyridinyl)ethanone

B

2-bromo-1-(5-ethylpyridin-2-yl)ethanol
646519-81-5

2-bromo-1-(5-ethylpyridin-2-yl)ethanol

C

2-(1-bromovinyl)-5-ethylpyridine

2-(1-bromovinyl)-5-ethylpyridine

Conditions
ConditionsYield
With N-Bromosuccinimide; water In tert-butyl alcohol at 25 - 30℃; for 1h; Product distribution / selectivity;A n/a
B 93%
C n/a
With N-Bromosuccinimide; water In dimethyl sulfoxide at -5 - 0℃; for 0.5h; Product distribution / selectivity;A 5%
B 88%
C 6%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

5-ethyl-2-oxiran-2-ylpyridine

5-ethyl-2-oxiran-2-ylpyridine

Conditions
ConditionsYield
Stage #1: 5-ethyl-2-vinyl-pyridine With N-Bromosuccinimide; water In tert-butyl alcohol at 25 - 30℃; for 1.5h;
Stage #2: With sodium hydroxide In water; tert-butyl alcohol for 0.75h; Product distribution / selectivity;
92%
Stage #1: 5-ethyl-2-vinyl-pyridine With N-Bromosuccinimide; water In dimethyl sulfoxide at -5 - 0℃; for 1h;
Stage #2: With potassium carbonate In methanol; water; dimethyl sulfoxide at 25 - 30℃; for 1h; Product distribution / selectivity;
80%
With N-Bromosuccinimide; acetic acid In water; tert-butyl alcohol at 10℃; for 1h; Reagent/catalyst; Solvent; Inert atmosphere; Large scale;
Multi-step reaction with 2 steps
1: water; N-Bromosuccinimide / tert-butyl alcohol / 1.17 h / 25 - 30 °C
2: potassium carbonate / tert-butyl alcohol; water / 1 h / 25 - 30 °C
View Scheme
Multi-step reaction with 2 steps
1: water; N-Bromosuccinimide / dimethyl sulfoxide / 0.5 h / -5 - 0 °C
2: potassium carbonate / tert-butyl alcohol; water / 1 h / 25 - 30 °C
View Scheme
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

phenindione
83-12-5

phenindione

2-phenyl-2-[-(5-ethyl-2-pyridyl)ethyl]indane-1,3-dione

2-phenyl-2-[-(5-ethyl-2-pyridyl)ethyl]indane-1,3-dione

Conditions
ConditionsYield
In ethanol for 40h; Heating;90%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

A

2-bromo-1-(5-ethylpyridin-2-yl)ethanol
646519-81-5

2-bromo-1-(5-ethylpyridin-2-yl)ethanol

B

2-(1-bromovinyl)-5-ethylpyridine

2-(1-bromovinyl)-5-ethylpyridine

Conditions
ConditionsYield
With N-Bromosuccinimide; water In dimethyl sulfoxide at -5 - 0℃; for 0.5h;A 88%
B 6%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

A

4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzaldehyde
471295-98-4

4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzaldehyde

B

4-[1-(5-ethyl-pyridin-2-yl)-2-hydroxy-ethoxy]-benzaldehyde
471296-00-1

4-[1-(5-ethyl-pyridin-2-yl)-2-hydroxy-ethoxy]-benzaldehyde

Conditions
ConditionsYield
Stage #1: 5-ethyl-2-vinyl-pyridine With N-Bromosuccinimide; water In tert-butyl alcohol at 25 - 30℃; for 1.5h; Industry scale;
Stage #2: With sodium hydroxide In water; tert-butyl alcohol for 0.75h; Industry scale;
Stage #3: 4-hydroxy-benzaldehyde With PEG 4000; sodium hydroxide In water; toluene at 78℃; for 17h; Product distribution / selectivity;
A 84%
B n/a
Stage #1: 5-ethyl-2-vinyl-pyridine With N-Bromosuccinimide; water In tert-butyl alcohol at 25℃; for 1.5h; Industry scale;
Stage #2: With sodium hydroxide In water; tert-butyl alcohol for 0.75h;
Stage #3: 4-hydroxy-benzaldehyde With sodium hydroxide In water; toluene at 78℃; for 17h; Product distribution / selectivity;
A 83%
B n/a
Stage #1: 5-ethyl-2-vinyl-pyridine With N-Bromosuccinimide; water; 18-crown-6 ether In tert-butyl alcohol at 25 - 30℃; for 1.5h;
Stage #2: With sodium hydroxide In water; tert-butyl alcohol for 0.75h;
Stage #3: 4-hydroxy-benzaldehyde With sodium hydroxide; 18-crown-6 ether In water; toluene at 78℃; for 24h; Product distribution / selectivity;
A 81%
B n/a
Stage #1: 5-ethyl-2-vinyl-pyridine With N-Bromosuccinimide; water In tert-butyl alcohol at 25 - 30℃; for 2.5h;
Stage #2: 4-hydroxy-benzaldehyde With potassium carbonate In tert-butyl alcohol at 75 - 80℃; for 18h; Product distribution / selectivity;
A 79%
B n/a
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzaldehyde
471295-98-4

4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzaldehyde

Conditions
ConditionsYield
Stage #1: 5-ethyl-2-vinyl-pyridine With N-Bromosuccinimide In water; tert-butyl alcohol at 25℃; for 1.5h; Large scale;
Stage #2: With sodium hydroxide In water; tert-butyl alcohol for 0.75h; Large scale;
Stage #3: 4-hydroxy-benzaldehyde With sodium hydroxide In water; toluene at 78℃; for 17h; Reagent/catalyst; Solvent; Temperature; Time; Large scale;
84%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

4-hydroxybenzaldehyde potassium salt
58765-11-0

4-hydroxybenzaldehyde potassium salt

4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzaldehyde
471295-98-4

4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]benzaldehyde

Conditions
ConditionsYield
Stage #1: 5-ethyl-2-vinyl-pyridine With N-Bromosuccinimide; water In tert-butyl alcohol at 25 - 30℃; for 2.5h;
Stage #2: 4-hydroxybenzaldehyde potassium salt In tert-butyl alcohol at 75 - 80℃; for 18h;
79%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

1-(2-Methoxyphenyl)piperazine
35386-24-4

1-(2-Methoxyphenyl)piperazine

(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

1-(2-methoxyphenyl)-4-<2-<2-(5-ethyl)pyridyl>ethyl>piperazine fumarate
90126-10-6

1-(2-methoxyphenyl)-4-<2-<2-(5-ethyl)pyridyl>ethyl>piperazine fumarate

Conditions
ConditionsYield
With acetic acid 1.) ethanol, 5 h, reflux; 2.) acetone;64%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

[(hydridotris(pyrazolyl)borato)RuCl2(NO)]
137729-45-4

[(hydridotris(pyrazolyl)borato)RuCl2(NO)]

(BH(C3H3N2)3)RuCl(NOC2H2NC5H3C2H5)

(BH(C3H3N2)3)RuCl(NOC2H2NC5H3C2H5)

Conditions
ConditionsYield
With triethylamine In dichloromethane treatment of Ru-complex with 2-vinylpyridine in the presence of excess of triethylamine in refluxing CH2Cl2;56%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

2-bromo[5-ethylpyridin-2-yl]ethyl bromide

2-bromo[5-ethylpyridin-2-yl]ethyl bromide

Conditions
ConditionsYield
With bromine In tetrachloromethane for 2h; Product distribution / selectivity;43%
With bromine In tetrachloromethane at 0 - 5℃; for 2h;
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

3-Ethyl-5-(5-ethyl-pyridin-2-yl)-5,6,7,8-tetrahydro-quinoline
76162-64-6

3-Ethyl-5-(5-ethyl-pyridin-2-yl)-5,6,7,8-tetrahydro-quinoline

Conditions
ConditionsYield
With PPA In phosphoric acid at 180 - 200℃; for 8h;42%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

N-phenyl-maleimide
941-69-5

N-phenyl-maleimide

5-(2,5-Dioxo-1-phenyl-pyrrolidin-3-yl)-8-ethyl-2-phenyl-3a,4,5,9b-tetrahydro-pyrrolo[3,4-f]quinoline-1,3-dione

5-(2,5-Dioxo-1-phenyl-pyrrolidin-3-yl)-8-ethyl-2-phenyl-3a,4,5,9b-tetrahydro-pyrrolo[3,4-f]quinoline-1,3-dione

Conditions
ConditionsYield
In acetic anhydride for 15h; Heating;30%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

1,3-di(aminomethyl)benzene
1477-55-0

1,3-di(aminomethyl)benzene

[3-({Bis-[2-(5-ethyl-pyridin-2-yl)-ethyl]-amino}-methyl)-benzyl]-bis-[2-(5-ethyl-pyridin-2-yl)-ethyl]-amine
147151-69-7

[3-({Bis-[2-(5-ethyl-pyridin-2-yl)-ethyl]-amino}-methyl)-benzyl]-bis-[2-(5-ethyl-pyridin-2-yl)-ethyl]-amine

Conditions
ConditionsYield
With acetic acid In methanol for 168h; Heating;18%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

carbonylchlorohydridotris(triphenylphosphine)ruthenium(II)
157072-60-1, 166941-05-5, 16971-33-8, 61521-25-3

carbonylchlorohydridotris(triphenylphosphine)ruthenium(II)

Ru(CH2CH2(C2H5C5H3N))Cl(CO)(P(C6H5)3)2

Ru(CH2CH2(C2H5C5H3N))Cl(CO)(P(C6H5)3)2

Conditions
ConditionsYield
In tetrahydrofuran under N2, a THF suspn. of 1 equiv of Ru-complex and 1.5 equiv of 5-ethyl-2-vinylpyridine was stirred at room temp. for 10 h; elem. anal.;17%
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

bis<2-(2-(5-ethylpyridyl)ethyl)>amine
154743-00-7

bis<2-(2-(5-ethylpyridyl)ethyl)>amine

Conditions
ConditionsYield
With ammonium chloride In methanol for 48h; Heating;16.5%
pyrrolidine
123-75-1

pyrrolidine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

5-ethyl-2-(2-pyrrolidino-ethyl)-pyridine
91904-22-2

5-ethyl-2-(2-pyrrolidino-ethyl)-pyridine

Conditions
ConditionsYield
With acetic acid
piperidine
110-89-4

piperidine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

5-ethyl-2-(2-piperidino-ethyl)-pyridine
43058-52-2

5-ethyl-2-(2-piperidino-ethyl)-pyridine

Conditions
ConditionsYield
With acetic acid
morpholine
110-91-8

morpholine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

4-[2-(5-ethyl-pyridin-2-yl)-ethyl]-morpholine
91904-47-1

4-[2-(5-ethyl-pyridin-2-yl)-ethyl]-morpholine

Conditions
ConditionsYield
With acetic acid
Thiophene-2-thiol
7774-74-5

Thiophene-2-thiol

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

5-ethyl-2-(2-[2]thienylmercapto-ethyl)-pyridine
100373-67-9

5-ethyl-2-(2-[2]thienylmercapto-ethyl)-pyridine

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

isoquinoline
119-65-3

isoquinoline

isoquinoline hydrochloride
21364-46-5

isoquinoline hydrochloride

2-[2-(5-ethyl-[2]pyridyl)-ethyl]-isoquinolinium; chloride

2-[2-(5-ethyl-[2]pyridyl)-ethyl]-isoquinolinium; chloride

Conditions
ConditionsYield
at 140℃;
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

indole
120-72-9

indole

3-[2-(5-ethyl-pyridin-2-yl)-ethyl]-indole
16571-55-4

3-[2-(5-ethyl-pyridin-2-yl)-ethyl]-indole

Conditions
ConditionsYield
With acetic acid
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

Succinimide
123-56-8

Succinimide

N-[2-(5-ethyl-[2]pyridyl)-ethyl]-succinimide
97030-49-4

N-[2-(5-ethyl-[2]pyridyl)-ethyl]-succinimide

5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

methanol
67-56-1

methanol

5-ethyl-2-(2-methoxy-ethyl)-pyridine

5-ethyl-2-(2-methoxy-ethyl)-pyridine

Conditions
ConditionsYield
With potassium hydroxide at 150℃; unter Druck;
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

1-methylindole
603-76-9

1-methylindole

3-[2-(5-ethyl-pyridin-2-yl)-ethyl]-1-methyl-indole
16568-58-4

3-[2-(5-ethyl-pyridin-2-yl)-ethyl]-1-methyl-indole

Conditions
ConditionsYield
With acetic acid
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

phthalimide
136918-14-4

phthalimide

N-[2-(5-ethyl-pyridin-2-yl)-ethyl]-phthalimide
17624-24-7

N-[2-(5-ethyl-pyridin-2-yl)-ethyl]-phthalimide

Conditions
ConditionsYield
With acetic acid at 140℃;
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

4-methyl pentanamine
5344-20-7

4-methyl pentanamine

[2-(5-ethyl-[2]pyridyl)-ethyl]-isohexyl-amine
131241-20-8

[2-(5-ethyl-[2]pyridyl)-ethyl]-isohexyl-amine

Conditions
ConditionsYield
With acetic acid
5-ethyl-2-vinyl-pyridine
5408-74-2

5-ethyl-2-vinyl-pyridine

thioacetic acid
507-09-5

thioacetic acid

thioacetic acid S-[2-(5-ethyl-[2]pyridyl)-ethyl ester]

thioacetic acid S-[2-(5-ethyl-[2]pyridyl)-ethyl ester]

Conditions
ConditionsYield
anfangs bei -40grad;

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