The reversible addition fragmentation chain transfer (RAFT) of N-(3-aminopropyl)methacrylamide hydrochloride (APMA) using unprotected “clickable” chain transfer agents in water/dioxane mixtures is reported. The controlled character of the polymerization was confirmed by the linear increase of ...

Spherical silica particles with bifunctional (Si(CH2)3NH2/SiC6H5) surface layers were synthesized by the Stöber method using ternary alkoxysilanes systems. The influence of the synthesis conditions, such as temperature and stirring time on the process of nanoparticles formation was studied. The ...

The research goal was to synthesize and structurally characterize a silatrane intended to be subsequently incorporated into metal complex structures. 3-Aminopropyltrialkoxysilane was reacted with triethanolamine in 1:1 molar ratio, either in bulk, in the presence of metallic sodium, or in a solv...

Coprecipitation method was used to prepare pure and doped CoFe2O4 nanoparticles. Ferric and cobalt salts were used as precursors while Sodium Dodecylbenzene Sulfonate was used as surfactant. Surface functionalization of cobalt ferrite nanoparticles (NPs) is a kind of functional materials, which ...

This work was initiated to determine whether toxicity generated through inhibition of mitochondrial fuel metabolism is similar to high glucose/palmitate (HG/PA)-induced glucolipotoxicity. Influx of glucose and free fatty acids into the tricarboxylic acid (TCA) cycle was inhibited by treatment wi...

The extracellular Ca2+ chelator EGTA and L-type Ca2+ channel blockers, such as, nifedipine and nimodipine were found to have a protective effect on palmitate-induced MIN6N8a beta cell apoptosis, whereas the Ca2+ channel opener, Bay K8644, enhanced the apoptotic process. Moreover, the phospho-for...

Ibead-CELipC12 is a metagenomic lipase, LipC12, immobilized directly from a crude extract onto Immobead 150. We evaluated its solvent and thermal stability and its potential for producing flavor esters and structured lipids. Ibead-CELipC12 had residual activities above 88% after 24 h at 40 °C i...

The esterification of palmitic acid with methanol was studied over mesoporous sulfated zirconia (SZ) solid acid catalyst, prepared by using CTAB cationic surfactant as a template. The effect of various reaction parameters has been studied. The catalyst showed an excellent activity with 88–90% y...

BackgroundPalm oil is the most consumed worldwide, being evident its importance due to several applications by the food industry. The presence of toxic and mutagenic compounds, such as chloropropanols and glycidyl fatty acid esters has increased the attention on this oil. Very recently, there ha...

For biodiesel production from waste cooking oils with high acid values, an inefficient esterification pretreatment is always conducted to convert free fatty acids (FFAs) before alkali-catalysed transesterification process. In this paper, phosphotungstic acid based poly(ionic liquid) was prepared...

The direct esterification of palmitic acid with l-(+)-arabinose has been carried out. The use of Candida antartica lipase B as the catalyst and the choice of suitable solvent and experimental conditions allowed carrying out the reaction successfully. In particular 10% dimethyl-sulfoxide in tert-...

The possibility of using 1,3-regioselective lipases for the synthesis of 2-monoolein and 1,2-diolein by ethanolysis of triolein was evaluated. The reactions were carried out in aqueous/organic two-phase systems, achieving high reaction rates due to the interfacial activation of the lipases. Diff...

The present study describes the production and characterization of monoolein aqueous dispersions (MAD) as drug delivery systems for curcumin (CR).MAD based on monoolein and different emulsifiers have been produced and characterized. Morphology and dimensional distribution have been investigated ...

Lipase extracted from Rhizopus oryzae was immobilized in alginate gel beads. The effects of the immobilization conditions, such as, alginate concentration, CaCl2 concentration and amount of initial enzyme on retained activity (specific activity ratio of entrapped active lipase to free lipase) we...

Bambusae Caulis in Taeniam extract (BCT) was loaded in monoolein cubosome including decanoyl alginate and decanoyl gelatin. The cubosome exhibited a suppressed release at an acidic condition. Carcinogenic fine dust induced-cell (RAW 264.7 cell) death was prevented more effectively by cubosomal B...

Monoolein cubic phase containing poly(hydroxyethyl acrylate-co-propyl methacrylate-co-methacrylic acid) was prepared by a melt-hydration method. The electric field (1.5 V, 3 V, and 4.5 V) promoted the release of amaranth (a negatively charged dye) loaded in the cubic phase. The release degree of...

Lysosomal Storage Disorders (LSDs) are characterized by an abnormal accumulation of substrates within the lysosome and comprise more than 50 genetic disorders with a frequency of 1:5000 live births. Nanotechnology may be a promising way to circumvent the drawbacks of the current therapies for ly...

Monoacylglycerols (MAGs) are precursors for the synthesis of many active lipids and an important amphiphilic emulsifiers which are widely used in food, pharmaceutical, and cosmetic industries. In this study, we reported an improved method for the synthesis of 1-monoolein using 1,2-acetonide glyc...

Alginate beads containing the polar lipid monoolein were developed as a strategy to manage wet wounds by providing improved uptake of excess exudate while releasing adenosine locally for promotion of healing. To obtain monoolein-containing beads, the lipid was mixed with almond oil (2:1 w/w), an...

The present investigation concerns the production and characterization of monoolein-water systems designed for cutaneous administration of crocetin. The different monoolein crystalline phases forming in the presence of crocetin as a function of added water have been investigated by x-ray and pol...