The miscibility behaviour of poly(2-cyanoethyl methacrylate) (PCYEMA) with various polymethacrylates has been studied by differential scanning calorimetry. PCYEMA is is immiscible with poly(ethyl methacrylate), poly(n-propyl methacrylate and poly(n- butyl methacrylate), but miscible with poly(me...

Synthesized Pyridin-2-yl hexanoate was screened for its antibacterial and antibiofilm activities using the broth microdilution method and XTT assay respectively. The obtained results revealed that synthesized molecule inhibited the growth of pathogenic bacteria (MICs value ranged from 80 to 640 ...

The modeling of the oxidation of methyl esters was investigated and the specific chemistry, which is due to the presence of the ester group in this class of molecules, is described. New reactions and rate parameters were defined and included in the software EXGAS for the automatic generation of ...

Vapor pressures of six saturated Fatty Acid Methyl Esters (FAMEs), methyl hexanoate (or methyl caproate), methyl octanoate (or methyl caprylate), Methyl decanoate (or methyl caprate), methyl dodecanoate (or methyl laurate), methyl tetradecanoate (or methyl myristate), and methyl hexadecanoate (o...

The toxicity of 1,2,6-hexanetriol was determined in rats, rabbits, and dogs. In rats the LD50 values are 16 ml/kg orally, 10 g/kg intraperitoneally, and 5.6 ml/kg intravenously. Inunctions of 2 ml/kg 30 times within 6 weeks produced no effect in rabbits. Fed in the diet of rats for 2 years, a 5%...

The metal catalyzed hydrogenolysis of the biomass-derived THF–dimethanol to 1,2,6-hexanetriol using heterogeneous catalysts was investigated. Bimetallic Rh–Re catalysts (4 wt% Rh and a Re/Rh (mol. ratio of 0.5) on a silica support gave the best performance and 1,2,6-hexanetriol was obtained in...

HMF (5-hydroxymethylfurfural) is a well-known promising product from hexose dehydration used for production of biofuels and chemicals. Liquid-liquid extraction is an essential process in HMF production to recover HMF from reaction medium. One of the important parameters needed in the extraction ...

In connection with the chemical-medicinal work 5-chloro-2-(3-chloro-2-hydroxypropoxy)-benzhydrylamine was prepared by a three-step synthesis. Compound I was reacted with epichlorohydrin and the formed 3-(2-benzyl 4-chlorophenoxy)-2-hydroxypropylchloride (II) was then converted to III by free-rad...

S-2-(3-tert-Butylamino-2-hydroxypropoxy)-3-cyanopyridine was recovered (∼90%) from human plasma and detected by conversion to a diheptafluorobutyryl derivative for electron-capture GLC. A homolog served as an internal standard. The method measures plasma drug concentrations at the 5-ng/ml level...

Depending on our previous observations, some compounds of pentanoic acid were designed and synthesized. Characterization of the synthesized compounds was done by mass, NMR and IR spectroscopy as well as elemental analysis. Among the synthesized molecules, (2S)-5-oxo-2-[(nitrobenzene-4-yl sulfony...

With the objective of developing novel chiral ligands, we report an efficient strategy to prepare chiral N,N-dimethyl-1,4-piperazines, six-member heterocyclic molecules that possess metal binding features. We prepared and characterized 18 piperazines, and evaluated their ability to complex diffe...

Readily available cyclic dehydrodipeptides are convenient starting materials for atom-efficient synthesis of different compounds. A one-pot ring-opening/alcoholysis/hydrolysis process with 3-nitroarylmethylene-2,5-piperazinediones yielded N-3-nitroarylpyruvoylamino esters, which gave the corresp...

3-Triphenylphosphonio-2,5-piperazinediones were effectively synthesized from homochiral valine or proline via Boc-Val-Gly-OMe, Boc-Pro-Gly-OMe or Cbz-Pro-Gly-OMe. Retention of configuration of the primary stereogenic center of the valine and proline moieties was observed. Diastereoselective nucl...

A neurologic deficit characterized by hypokinesia, postural flexion, and to a lesser extent, rigidity, tremor and myoclonus, has been observed in cynomolgus monkeys following administration of 1-methyl-4-(1-methylpyrrol-2-yl)-4-piperidinol (MMPP), a novel 4-substituted piperdine. The syndrome, s...

A detailed study of the products of elimination of some 4-aryl-3-methyl-4-piperidinols has been made and the PMR spectra of derived 1-alkyl (and aralkyl)-4-aryl-5-methyl-1,2,5,6-tetrahydropyridines and the corresponding hydrochloric salts reported and discussed. The 5-methyltetrahydropyridine hy...

In our study, the effects of the compound 3-benzoyl-1-methyl-4-phenyl-4-piperidinol hydrochloride (C1) and also an anti-inflammatory drug, indomethacin, tested by carrageenan-induced paw edema and cotton pellet granuloma tests, for their effects on acute and chronic phases of inflammation, respe...

Organic carbonyl compounds are considered as promising candidates for lithium batteries due to their high capacity and environmental friendliness. However, they suffer from serious dissolution in the electrolyte, leading to fast capacity decay. Here we report core-shell structured 1,[email prote...

A density functional theory computational study of poly(2,5-diaza-1,4-benzoquinone) as a potential organic cathode is presented. The lithium insertion in one-dimensional, two-dimensional and three-dimensional models was evaluated and yielded energies of 2.38, 3.12 and 3.59 eV per Li atom, respec...

Gel polymer electrolyte (GPE) is recently attracting a significant attention for lithium air batteries (LABs) due to better reliability compared with liquid type electrolyte and higher ionic conductivity compared with solid type electrolyte. In this paper, we report a new combination of polyacry...

UV–Vis, FT-IR, LC–MS and fluorescence spectral techniques were employed to investigate the mechanism of interaction of l-phenylalanine with new π-acceptors, 6-alkoxy-2,3,5-trichloro-1,4-benzoquinones. The interaction of these quinones with l-phenylalanine (LPA) yielding radical ion pair was f...