The guppy (Lebistes resticulatus) and coontail (Ceratophyllum demersum) were exposed to water containing 203Hg-labeled ethylmercuric chloride (EMC). The EMC uptake was related to the time of exposure and the concentration of EMC. Highest concentration of 203Hg was found in the internal organs of...

Ethylmercuric chloride was given to chicks and rats intramuscularly and orally. The compound is apparently absorbed unchanged. Metabolism of ethylmercury is much slower than of phenylmercury. Intact ethylmercury is detectable in the liver and kidneys for 21 days after dosing. The ethylmercury is...

Ethylmercuric chloride (EMC) labeled with 203Hg was administered to rats, and the chemical nature of the mercury compound which accumulated in the blood was investigated.More than 97% of the total mercury in the blood of the EMC-treated rats was extracted with dithizone as organic mercury dithiz...

Methods for the analysis of the mercury compounds in biological samples were established and applied to the investigation of the metabolic fate of ethylmercuric chloride-203Hg in rats. Analyses of mercury compounds contained in the liver, kidney, urine, and feces of rats treated with ethylmercur...

Aligned micro- and nanoporous materials have gained tremendous interest since they provide great potential in organic electronics, absorbents, biomedicine and tissue engineering. Herein, cellulose nanofibrils (CNFs) and cellulose nanocrystals (CNCs) cross-linked with poly(methyl vinyl ether-co-m...

This study investigates the nitrate radical oxidation of methyl vinyl ether (CH2CHOCH3, MVE) by quantum chemical methods. The oxidation initiates with the formation of open-cyclic NO3-adducts, followed by a series of unimolecular decomposition or bimolecular reactions. Kinetic data suggest that ...

Among the species of potential interstellar relevance, methyl vinyl ether (CH3OCHCH2) is the simplest ether compound containing both alkyl and alkene functional groups. In order to facilitate its detection in the ISM, we have measured the millimeter and submillimeter wave spectra from 50 to 650 ...

Traditional ethylene glycol production is heavily dependent on oil. In the background of richness of coal and scarcity of oil, more and more coal to ethylene glycol (CTEG) plants have been successfully operated to relieve the shortage of ethylene glycol in China. Thus, it is an urgent work to an...

Slow electro-oxidation reaction and low power output are two major limiting factors in successful commercialization of fuel cell technology. An efficient and stable electro-catalyst with effectual metal combination supported on a durable matrix may provide a viable solution to overcome these iss...

The pyrolysates of chloroacetaldehyde and its methyl derivatives have been investigated by pyrolysis-mass spectrometry and microwave spectroscopy. Ketene was generated by dehydrochlorination of chloroacetaldehyde. Ketene and s-trans-acrolein were produced by the elimination of methyl chloride an...

Chloroacetaldehyde (CAA) is a metabolite of the human carcinogen vinyl chloride. CAA produces several types of DNA adducts including the exocyclic base adducts 3,N4-ethenocytosine, 1,N6-ethenoadenine, N2,3-ethenoguanine, and 1,N2-ethenoguanine. Adducts of CAA with 5-methylcytosine have not yet b...

Ethnopharmacological relevanceSchisandra chinensis (Turcz.) Baill (S. chinensis) has been used for thousands years in China, and is usually applied in treatment of urinary tract disorders and liver injury. S. chinensis extract (SCE) has board protective effects on liver, kidney and nervous syste...

We have analyzed the modification of the mass transfer due to chloroacetaldehyde (CAA) inside a renal barrier model. For that purpose, the Madin–Darby Canine Kidney (MDCK) cell line was cultivated onto a polyethersulfone (PES) membrane. The membrane supporting a junctive cell layer was sandwich...

A sensitive and selective reversed-phase liquid chromatographic assay for tenofovir in human plasma has been developed and validated. Tenofovir was isolated from a 200 μl plasma sample using protein precipitation with trichloroacetic acid. The fluorescent 1,N6-etheno derivative is formed at 98 ...

Cyclophosphamide and ifosfamide are two commonly used DNA-alkylating agents in cancer chemotherapy that undergo biotransformation to several toxic and non-toxic metabolites, including acrolein and chloroacetaldehyde (CAA). Acrolein and CAA toxicities occur by several different mechanisms, includ...

Chloroacetaldehyde, one of the main products of hepatic ifosfamide metabolism, contributes to its nephrotoxicity. However, the pathophysiology of this toxicity is not fully understood. The present work examined the time and dose effects of clinically relevant concentrations of chloroacetaldehyde...

DNA damage is ubiquitous and can arise from endogenous or exogenous sources. DNA-damaging alkylating agents are present in environmental toxicants as well as in cancer chemotherapy drugs and are a constant threat, which can lead to mutations or cell death. All organisms have multiple DNA repair ...

1,2-Dichloroethane (1,2-DCE) is oxidatively converted to a carcinogenic intermediate compound, chloroacetaldehyde by chloroacetaldehyde dehydrogenase (CAldA) during its biodegradation by many bacterial strains, including Xanthobacter autotrophicus and Ancylobacter aquaticus. In this study, a 55 ...

The challenging carbonylation of propargyl alcohol is effectively catalyzed by Pd(OAc)2 in combination with diphenyl-(6-methyl-pyridin-2-yl)phosphine and methanesulfonic acid. In dichloroethane at 20–50 °C, the reaction affords with almost complete regioselectivity alkyl 2-(hydroxymethyl)acryl...

Platinum vinylcarbene complexes are potentially useful for organometallic synthesis and catalysis, but have been rarely studied. This work reports a convenient route to make platinum vinylcarbene complexes. Treatment of [PtCl2(PPh3)]2 with propargyl alcohols HC≡CC(OH)RR’ (RR’ = Ph2, cyclo-C6H...