The effect of mixed mutagen exposures on the rate and type of induced mutants was studied in the L5178Y/TK+/− → TK−/− mouse lymphoma cell mutagenicity assay. In this assay, exposure to ethyl methanesulfonate (EMS) results in more mutants that form large colonies than small colonies. Exposure to...

The reaction of R2Sn(OH)OSO2Me [R=n-Pr (1a), or n-Bu (1b)] with one equivalent of Bu4NNO3 in CH2Cl2 proceeds via nucleophilic addition of NO3 − ion to the Lewis acidic tin center and results in the formation of novel diorganostannates, [R2Sn(μ-OH)(OSO2Me)(ONO2)]22Bu4N [R=n-Pr (2a), n-Bu(2b)]. T...

The activity coefficients at infinite dilution, γ13∞, for 43 solutes, including alkanes, cycloalkanes, alkenes, alkynes, aromatic hydrocarbons, alcohols, water, thiophene, ethers, ketones, acetonitrile, pyridine, and 1-nitropropane in the ionic liquid 1-ethyl-3-methylimidazolium methanesulfona...

Oligoprenyl phosphates are key metabolic intermediates for the biosynthesis of steroids, the side chain of ubiquinones, and dolichols and the posttranslational isoprenylation of proteins. Farnesyl phosphates are isoprenoid phosphates that resemble polyunsaturated fatty alcohol phosphates, which ...

Farnesyl diphosphate synthase (FPS) is an essential enzyme in the biosynthesis of prenyl precursors for the production of primary and secondary metabolites, including sterols, dolichols, carotenoids and ubiquinones, and for the modification of proteins. Here we identified and characterized two F...

Various homopolyamides and copolyamides bearing olefinic bonds and pendent cyano groups were prepared by reacting aromatic diamines with the acid chloride of 1,4-bis(2-cyano-2-carboxyvinyl)benzene. In addition, the latter reacted with aniline to afford a model diamide. The monomers were characte...

4-Carboxybenzaldehyde was condensed with cyanoacetic acid to afford 1-carboxy-4-(2-cyano-2-carboxyvinyl)benzene (1). Homopolyamides were prepared from the polycondensation of 1 with aromatic diamines utilizing triphenyl phosphite and pyridine as condensing agents. In addition, various copolyamid...

4-Hydroxybenzaldehyde or 3-methoxy-4-hydroxybenzaldehyde was condensed with cyanoacetic acid to afford 1-hydroxy-4-(2-cyano-2-carboxyvinyl)benzene (1) and 1-hydroxy-2-methoxy-4-(2-cyano-2-carboxyvinyl)benzene (2) respectively. They were converted to the corresponding acid chlorides by reacting w...

This article provides a critical review and a wide range of applications of dithiocarbamates (DTCs) in environmental samples. The characteristics of DTCs are reviewed with particular emphasis on inorganic speciation studies using state-of-the-art analytical instrumentation coupled with computati...

Ultrasound-assisted co-precipitation was applied to construct a magnetic nanocomposite following a ‘one-pot’ synthetic strategy for Hg(II) enrichment. The presence of a noble metal such as Ag(I), Au(III), Pd(II) in the synthesis medium proved to be essential in order to attain an efficient co-...

Five new organotin(IV) dithiocarbamate complexes of the form R2SnL2 (R = nBu, L = L1, (4-phenylpiperazine-1-dithiocarbamate) 1, L2, (N-benzyl-N′-methyl-4-pyridyldithiocarbamate) 2; Ph, L3, (N-benzyl-N′-methyl-3-pyridyldithiocarbamate) 3) and Ph3SnL (L = L4, (N,N′-di(methyl-3-pyridyldithiocarb...

Metal-directed self assembly of ferrocenyl based pyridyl functionalized dithiocarbamates afforded the novel macrocyclic metal-organic coordination polymers, [M(L)2]∞ (M = Zn(II), L = L2 (N-ferrocenylmethyl-N-pyridin-4-ylmethyl) dithiocarbamate 2, M = Cd(II), L = L1 (N-ferrocenylmethyl-N-pyridin...

The electron-donating group dithiocarbamate functionalized silica gel (SG-PDC) was prepared and used for adsorption of metal ions from aqueous solution. The modified silica gel was characterized by fourier transform infrared spectroscopy (FT-IR), elemental analysis (EA) and scanning electron mic...

Bacterial and fungal infections are the major effects to cause the numerous disorders in health. To overcome such disorders there will be needed to carry out the studies to find potent antimicrobial agents from many years. The titled compounds containing coumarin-dithiocarbamate hybrids have eme...

Mercury is one of the most toxic heavy metals found in solid and liquid waste disposed by chloro-alkali, paint, paper/pulp, battery, pharmaceutical, oil refinery and mining companies. Any form of mercury introduced to nature through any means is converted into a more toxic form such as methylmer...

A series of six N′N-diarylformamidine dithiocarbamate ligands and their metal complexes of Cu(II) and Ni(II) chloride salts have been synthesized. Three symmetrical, N,N′-bis(2,6-dimethylphenyl)formamidine dithiocarbamate (DL1), N,N′-bis(2,6-disopropylphenyl)formamidine dithiocarbamate (DL2),...

Infrared and Raman spectra of protoporphyrin IX were recorded. DFT quantum chemical calculations were performed. Optimised molecular geometry, electric charge distribution, vibrational force constants were computed. The normal coordinate analysis and the scaling of the force constants yielded al...

An efficient and selective catalytic process to promote the hydroformylation of protoporphyrin-IX dimethyl ester, the respective nickel(II) and zinc(II) complexes and also of methyl pheophorbide a allomer is described. The effect of the central metal ion, pressure, temperature and phosphine liga...

Time-resolved Raman and adsorption spectroscopies were used to characterize the vibrational and electronic structure of the *B1g excited state of nickel(II) protoporphyrin IX dimethyl ester. Evidence for structural relaxation processes within the initial B1g excited state was observed on picosec...

Listeria innocua DNA binding protein from starved cells (LiDps) belongs to the ferritin family and provides a promising self-assembling spherical 12-mer protein scaffold for the generation of functional nanomaterials. We report the creation of a Gaussia princeps luciferase (Gluc)-LiDps fusion pr...