(Z)- and (E)-2-(3′,4′-Dimethoxybenzoyl)benzyl cinnamate (3Z and 3E) and (E)-N-(2-(3′,4′-dimethoxybenzoyl)benzoxycarbonymethyl) cinnamide (4E) have been prepared. The photosensitized isomerization of cinnamates via intramolecular triplet–triplet (T–T) energy transfer from the triplet 2-dime...

Black soldier fly larvae containing high lipids had been considered an novel sustainable feedstock for lipid extraction to biofuels. The insect lipid was extracted with microwave assisted solvent extraction method. The energy consumption of this way was analyzed to determine the feasibility of t...

The synthesis and highly stereoselective intramolecular cyclization reactions of a series of (2-pyridylthio)glycosides possessing silyl enol ether-containing appended groups are described. The cyclizations are explained in terms of SN1-like reactions proceeding via anomeric cationic species.

X-ray diffraction reveals that the molecular structures of the tris(pyrazolyl)hydroborato and tris(2-pyridylthio)methyl lithium compounds, [TpBut,R]Li (R = H, Me) and [κ4-Tptm]Li, respectively exhibit three-coordinate trigonal pyramidal and four-coordinate trigonal monopyramidal coordination ge...

The complexes [Cd2Cl4(bpytm)] (1), [CdBr2(bpytm)] (2), [Cd2Br4(bpytm)] (3) and [CdI2(bpytm)] (4) [bpytm=bis(2-pyridylthio)methane] were prepared and characterized by elemental chemical analysis, by IR, Raman and 1H and 13C NMR spectroscopy, and in the cases of 2 and 4 by X-ray diffractometry. In...

The new sodium bis(2-pyridylthio)acetate ligand, Na[(pyS)2CHCO2], has been prepared in ethanol solution using 2-mercaptopyridine, dibromoacetic acid and NaOH. New mono- and di-organotin(IV) derivatives containing the anionic bis(2-pyridylthio)acetate have been synthesized from reaction between S...

A new one-dimension complex, [Cd(μ2-L)2]n (1, HL=3-(2-pyridyl)pyrazole), has been hydrothermally synthesized and characterized by elemental analysis, IR, TGA, and single-crystal X-ray diffraction analysis. In 1, the L ligand takes tridentate chelating-bridging coordination mode via deprotonatio...

Three rhenium(I) carbonyl complexes with 4′-(n-pyridyl)−2,2′:6′,2′′- terpyridines (n-pytpy; n = 2, 3 and 4), coordinated to the central metal in a bidentate mode, have been synthesized in order to explore the impact of 2-, 3- and 4-pyridyl substituents on the thermal, photoluminescent, and ...

Photolysis of 1-(n-pyridyl)-2-(pentamethyldisilanyl)ethynes (n=2,3, or 4) 1, 9, or 20, respectively, aza analogs of 1-phenyl-2-(pentamethyldisilanyl)ethyne, was performed in both non-polar and polar solvents. In benzene, they provide silacyclopropene and 1-sila-1,2-propadiene intermediates but a...

The Schiff bases N-2-(4/6-methyl-pyridyl)salicylaldimine (HL) which are geometric isomers differing in the para- or ortho-position of the methyl group to the pyridyl nitrogen atom react with zinc(II) acetate to give the bis-ligand chelate complexes bis[N-2-(4/6-methyl-pyridyl)salicylaldiminato-κ...

Reaction of pyridyl Schiff base ligands, N-2-(R-pyridyl)-2-hydroxy-1-naphthaldimine (HL) with copper(II) acetate provides the bis[N-2-(R-pyridyl)-2-oxo-1-naphthaldiminato-κ2N^O]copper(II) (R = H: 1, 4/6-CH3: 2/3). Electronic spectra show the bands at

The Schiff base ligands N-2-(R-pyridyl)-2-hydroxy-1-naphthaldimine (HL) react with the zinc(II) nitrate or acetate to give the Λ- and Δ-bis[N-2-(R-pyridyl)-2-oxo-1-naphthaldiminato-κ2N,O]zinc(II), [Zn(L)2] {R = H (1), 4/6-CH3 (2/3)}. EI-mass spectra show the molecular ion peaks at 558 (1) and...

Epilepsy is a group of neurological disorders characterized by recurrent seizures that disturbs about 60 million people worldwide. In this article, a novel series of 3,4,5-trimethoxycinnamic acid (TMCA) ester derivatives 1–35 were designed inspired from the traditional Chinese herb pair drugs P...

A series of cis-restricted 2-alkylthio-4-(2,3,4-trimethoxyphenyl)-5-aryl-thiazole analogues of combretastatin A-4 were synthesized and investigated for inhibition of cell proliferation against three cancer cell lines, HT-29, MCF-7, and AGS, and a normal mouse fibroblastic cell line, NIH-3T3, usi...

Colchicine mimetic (±)-4S,5R-4-nitro-5-(2,3,4-trimethoxyphenyl)cyclohexene (1) was epoxidized to afford a mixture of epoxides. The epoxides were separately converted in two steps, with high stereoselectivity, to two regioisomeric α-methoxyketones. One regioisomer, (±)-2R,4S,5R-2-methoxy-5-nit...

The convergent synthesis of methyl sulfomycinate and sulfomycinic amide, two acidic methanolysis products of the sulfomycin thiopeptide antibiotics, is achieved starting from diethoxyacetonitrile. Further confirmation of structure is obtained by heating methyl sulfomycinate at 110 °C in hydroch...

The design, synthesis, and evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]imidazolo[4,5-e]indol-4-one-6-carboxylate (CImI) derivatives are detailed representing analogs of duocarmycin SA and yatakemycin containing an imidazole replacement for the fused pyrrole found in the DNA alkylation s...

Using (trifluoromethyl)trimethylsilane (TMSCF3) as the trifluoromethylating agent, MgCl2-catalyzed trifluoromethylation of carbonyl compounds proceeded readily at room temperature. In the presence of 10 mol% of MgCl2, a variety of carbonyl substrates such as aliphatic/aromatic aldehydes, acyclic...

Bacterial hyaluronan lyases (Hyal) degrade hyaluronan, an important component of the extracellular matrix, and are involved in microbial spread. Hyal inhibitors may serve as tools to study the role of the enzyme, its substrates and products in the course of bacterial infections. Moreover, such e...

A novel method for the quantification of loureirin B in rat plasma using high-performance liquid chromatography/tandem mass spectrometry (LC–MS/MS) was developed. Loureirin B and internal standard (buspirone) were extracted by liquid–liquid extraction and separated on a Agilent XDB C18 column ...