In the course of a study on the role of Ca2+ in the regulation of the secretion process in a female accessory sex gland, the albumen gland of the freshwater snail Lymnaea stagnalis, it appeared that the percentage of mitochondria containing Ca2+ deposits varied significantly in the successive st...

The cerebral caudodorsal cells (CDC) of the pulmonate snail Lymnaea stagnalis control egg-laying and associated behaviors. They produce various peptides derived from two precursor molecules, proCDCH-I and II, one of which is calfluxin (CaFl). CaFl is involved in the control of the activity of a ...

The caudodorsal cells of Lymnaea and the bag cells of Aplysia are neuroendocrine cells whose peptide products have homologous functions, i.e., regulation of egg deposition. One of the Lymnaea products, calfluxin, increases cytosolic and hence mitochondrial calcium concentrations in secretory cel...

The percentage of Ca2+ positive mitochondria in the cells of the albumen gland ofLymnaea stagnalis was used as a measure for the effect of the gonadotropic hormone calfluxin (CaFl) and for the interaction between schistosomin, an agent present in the hemolymph of snails infected with the schisto...

Murine reticulum cell sarcoma (M5076) was subcutaneously implanted into BDF1 mice and then the antitumor activity of seven micelle-forming type platinum complexes was tested. The antitumor activity of bis(hyodeoxycholato)-trans-(±)-1,2-cyclohexanediammineplatinum(II)(t-DACHP(hyo)2)) was highest...

Deuterated 26-hydroxycholesterol disulfate has been given in a tracer amount to neonates to evaluate the pool size, metabolism and excretion of the endogenously occurring compound in meconium. In a group of 5 normal neonates excretion of endogenous 26-hydroxycholesterol during the initial 72 h o...

Reaction of M(tBu)3 (M=Al, Ga) with 2,2-dimethyl-1,3-propanediamine (dmpa-H4) yields the thermally stable Lewis acid–base complexes (tBu)3M(dmpa-H4), M=Al (1) and Ga (2), respectively. The reaction of 2 with Ga(tBu)3 yields the formation of [(tBu)3Ga]2(dmpa-H4) (3). In contrast, reaction of dmp...

Two new copper (II) complexes, [Cu(N-Metn)2Cl]BF4 (1) and [Cu(Me2tn)2(N3)]N3 (2) (N-Metn = N-methyl-1,3-propanediamine; Me2tn = 2,2-dimethyl-1,3-propanediamine), have been prepared, fully characterized, and their structures established by X-ray single-crystal analysis from synchrotron diffractio...

A series of novel enantiomerically pure spiroisoxazolidines were synthesized regioselectively by the 1,3-dipolar cycloaddition of C-aryl-N-phenylnitrones to (R)-1-(1-phenylethyl)-3-[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones. These compounds have been screened for their in vitro activity a...

Coupling of 5-dimethylaminomethylene-3-methyl-2-(pyridine-2-ylimino)-thiazolidin-4-one (3) with diazotized methyl anthranilate afforded the 3-methyl-5-(2-methoxycarbonylphenylhydrazono)-2-pyridine-2-ylimino)thiazolidin-4-one (5). Reaction of 2-(arylamino)thiazol-4-ones 1a,b with arylidenemalonon...

Background: To date whether the effects of parental corporal punishment (CP) on executive function (EF) distinct components are different is less clear. Moreover, theory and empirical work suggest that physiological regulation system may help to explain the individual differences in the developm...

Carotenoids are fat-soluble pigments primarily found in fruits and vegetables. They accumulate in human skin and contribute to skin yellowness, which has a favorable effect on appearance. The association between specific fruit and vegetable intakes and skin yellowness is currently unknown and co...

Potential utilization of hematite as a natural material for immobilization of long-lived radionuclides from radioactive liquid waste was investigated. Hematite ore has been characterized by different analytical tools such as Fourier transformer infrared (FTIR), X-ray fluorescence (XRF), powder X...

The aim of the present study was to compare the differences of Zn-induced antioxidant defense, immunotoxicity and Zn homeostasis between the proximal and distal intestines of the large yellow croaker Larimichthys crocea. Fish were exposed to Zn (2 and 10 mg L-1) for 96 h. In the proximal intesti...

Marine-derived nutrients are known accumulate in seabird breeding colonies due to the deposition of nutrient-rich biological materials, thus greatly altering the functioning and dynamics of these terrestrial ecosystems. Here we present the results of a sampling survey carried out during three ye...

We study the surface morphology, mass loss and wetting of fluorinated ethylene propylene surfaces which have been treated using reactive ion etching. We find that etching with argon gas alone results in a network structure, while oxygen combined with argon results in pyramidal hair-like structur...

Mercury (Hg) is a trace element of particular concern since it is ubiquitous in the environment and because its methylated form (MeHg) readily bioaccumulates and biomagnifies in food webs. This latter process leads to elevated Hg concentrations in fish and may thus induce toxicity. Maternal tran...

Broccoli undergoes yellowing very quickly in storage, which impacts its’ quality and economic value. The current study examined the ability of putrescine to inhibit postharvest yellowing of broccoli florets. Broccoli heads were dipped in a 0.25 mmol L−1 solution of putrescine for 10 min, air dr...

Botulinum toxin has emerged as an important therapeutic intervention within the realm of movement disorders, especially for focal and generalized dystonias. Botulinum toxin has additionally been used for a variety of symptoms associated with parkinsonism. In this review, we will specifically eva...

The structure activity relationships of 2-oxy pyridine derivatives in the C-region of N-(6-trifluoromethyl-pyridin-3-ylmethyl) 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as hTRPV1 antagonists were investigated. The analysis indicated that the lipophilicity of the 2-oxy substituents was...