In this study, synthetic titanium white waste acid was concentrated by direct contact membrane distillation (DCMD) using laboratory prepared PVDF hollow fibers. Tentative efforts were made to decouple the effects of different factors on wetting and DCMD performance. FeSO4 crystals were found hom...

Di-(2-ethylhexyl) phosphoric acid coated silanized magnetite nanoparticles were applied for the rapid removal and fast adsorption of molybdenum ions from simulated nitric acid solutions. The characterization of the developed adsorbent was carried out using various analytical techniques such as T...

Decomposition of mineral sphene, CaTiOSiO4, by H3PO4 is investigated in detail. During the dissolution process, simultaneous calcium leaching and formation of titanium phosphate (TiP) take place. The main product of decomposition is a solid titanium phosphate–silica composite. The XRD, solid-sa...

In this paper, a novel purification method utilizing polymorphism to reduce LHB in the final product of LH has been employed. Two polymorphs of lincomycin hydrochloride (LH), polymorph I and polymorph II, are prepared, and their purities are determined by HPLC. The content of lincomycin B hydroc...

Cycloadditions of (1Z,4R*,5R*)-4-benzoylamino-5-phenylpyrazolidin-3-on-1-azomethine imines to olefinic dipolarophiles were studied. Stereochemistry of cycloadditions to azomethine imines 3 was found to be controlled by stereodirecting phenyl group at position 3, as well as by the ortho-substitue...

A library of 15 1,6,7,9-tetrasubstituted 6,7,9,9a-tetrahydro-5H-pyrazolo[1,2-a]pyrrolo[3,4-c]pyrazole-1,3,5(2H,3aH)-triones was prepared by combinatorial stereoselective cycloadditions of (1Z,4R∗,5R∗)-1-arylmethylidene-4-benzoylamino-5-phenylpyrazolidin-3-on-1-azomethine imines to N-substituted ...

A number of cyclometalated palladium(II) complexes [PdCl(pyC6H4)(L)] containing amino-pyridine or acetylamino-pyridine co-ligands (L) have been prepared from the reaction of [Pd(pyC6H4)(μ-Cl)]2 with two equivalents of these ligands. Crystal structures of four examples have been carried out, eac...

A novel chiral derivatization reagent, (S)-1-methyl-4-(5-(3-aminopyrrolidin-1-yl)-2,4-dinitro-phenyl)piperazine (APy-PPZ) was developed for the enantiospecific determination of chiral carboxylic acids in high-performance liquid chromatography. APy-PPZ reacted with carboxylic acids within 10 min ...

4-Acetylamino-3-arylazo-1,2,5-oxadiazole 2-oxides (furoxans) undergo two successive (cascade) mononuclear heterocyclic rearrangements in an aqueous basic medium with the formation of 4-acetylamino-2-aryl-5-nitro-2H-1,2,3-triazoles.

Ring-opening metathesis polymerization (ROMP) derived monoliths were prepared from 5-norborn-2-enemethyl bromide (NBE-CH2Br) and tris(5-norborn-2-enemethoxy)methylsilane ((NBE-CH2O)3SiCH3) within the confines of surface-silanized borosilicate columns (100 mm × 3 mm I.D.), applying Grubbs’ firs...

Bakuchiol belongs to a family of monoterpene phenols occurring in plant Psoralea corylifolia L., a traditional herbal medicine. Bakuchiol has also demonstrated multiple pharmacologic activities. However, metabolism of bakuchiol had never been investigated. The major objective of the present stud...

Bakuchiol, the main active component of Psoralea corylifolia, showed a range of significant pharmacological activities, including antimicrobial, antiinflammatory, reduction of bone loss and estrogenic activities. In this research, 12 metabolites, including 11 new compounds, were isolated from th...

Androgen-independent prostate cancer (PCa) is a developed tumor derived from the local androgen dependent PCa, which often affects elderly men. Psoralea corylifolia L, a traditional Chinese medicine, has been widely used for PCa treatment as an important part of a common prescription, while the ...

Bakuchiol, one of bioactive compounds isolated from the dried ripe fruits of Psoralea corylifolia L., possesses a variety of pharmacological activities. In this study, the metabolites of bakuchiol in rat liver microsomes as well as their cytotoxicities were studied. A total of eight metabolites ...

Estrogens and androgens play critical roles during benign prostatic hyperplasia (BPH) development. Estrogen receptors (ERs), androgen receptor (AR) and aromatase, the key conversion enzyme of androgen to estrogen, are thought to be the effective targets for BPH treatment. Bakuchiol (Ba)-containi...

The purpose of this work was to characterize PVC and agalmatolite composites and to evaluate the effects of this mineral filler through thermal analysis and mechanical property measurements. The glass transition temperature, as well as some mechanical properties, were evaluated through comparati...

We present two surface-immobilization schemes that connect an azurin variant with mutations in the redox cavity to two oligophenylvinyl (OPV) molecular wires, along with an electrochemical study of their electron transfer (ET) properties. OPV embedded within alkanethiol films tether selectively ...

Azurin is a bacterial protein from Pseudomonas aeruginosa which exerts an inhibitory activity in cancer cells. In P-cadherin-overexpressing models, a bad prognosis marker in breast cancer increasing invasion and other malignant features, azurin decreases the invasion of cancer cells.We performed...

We developed a multi-functional 4-bit biomemory chip that consisted of recombinant azurin variants. The azurin was modified to introduce cysteine-residues. In addition, the Cu ion in this recombinant azurin protein was substituted with various other metal ions such as Co, Mn, Fe and Ni ion to al...

In the present study, we developed a biohybrid material composed of recombinant azurin and CdSe-ZnS quantum dot to perform as a resistive random access memory (ReRAM) device. Site specific amino acid sequences were introduced in azurin to bind with the surface of CdSe-ZnS nanoparticle allowing t...