The cis-[Ru(bpy)2(clbzpy)(Cl)](PF6) complex (I), where clbzpy = 4-(4-chlorobenzoyl)pyridine and bpy = 2,2′-bipyridine, was prepared and fully characterized. Blue light photolysis (453 nm) of this compound in aqueous solution led to release of clbzpy and formation of the cis-[Ru(bpy)2(H2O)Cl]+ i...

Small molecular organic light-emitting diodes (MOLED) and polymer organic light-emitting diodes (POLED) were fabricated with yellow light emission phosphorescent dye bis[2-(4-tert-butylphenyl)benzothiazolato-N,C2′] iridium (III) (acetylacetonate) doped in different hosts. The electroluminescent...

Controlled radical polymerization of methyl methacrylate and styrene initiated by azobisisobutironitrile or benzoyl peroxide in the presence of a chlorine-containing complex of FeIII with 5,15-bis(4’-tert-butylphenyl)-2,8,12,18-tetra(n-butyl)-3,7,13,17-tetramethylporphyrin was investigated.

The effect of 1,3,5-Tris(1-phenyl-1H-benzimidazol-2-yl)benzene (TPBi) doping on electroluminescent properties of poly[N,N′-bis(4-butylphenyl)-N,N′-bis(phenyl)benzidine] (poly-TPD) was investigated. A series of organic light-emitting devices (OLEDs) integrated with (i) single-layer poly-TPD, (i...

Organic light-emitting devices (OLEDs) with a poly(N,N′-bis-4-butylphenyl-N,N′-bisphenyl)benzidine (poly-TPD):octadecylamine (ODA)-graphene quantum dots (GQDs) hole transport layer (HTL) were fabricated to enhance their efficiency. Photoluminescence (PL) and PL excitation spectra showed that t...

Two series of 1-phenylpiperazinylpropyl derivatives 10, 11, 16, 17 and 19–24, structurally related to previously described 5-HT1A or 5-HT2A ligands 4 and 1, respectively, were synthesized and their binding properties were determined. Structural modifications which involved 1,3-diazepine ring op...

A new series of 4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid amide and 3,5,6,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4-one derivatives were designed, synthesized, their binding and functional properties as α1-adrenoreceptors blockers were evaluated. A new validated α...

1,3,4,6-Tetra-O-acetyl-2-chloroacetamido-2-deoxy-β-d-glucopyranose was tested as a glycosyl donor for oligosaccharide synthesis via a ferric chloride-catalyzed coupling reaction. Glycosyl acceptors tried (6 in all) were O-benzyl-protected d-galactosides having free OH groups at positions 3 and ...

The asymmetric oxidation of 2-substituted dithianes, dithiolanes and oxathiolanes catalyzed by cyclohexanone monooxygenase (CMO) has been examined. The introduction of substituents at the C-2 causes a decrease of the e.e. with the exception of 2-benzoyl-1,3-dithiane monosulfoxide (90% e.e.). Wit...

The recently discovered cyclohexanone monooxygenase from Thermocrispum municipale (TmCHMO) was employed in the preparation of different optically active sulfoxides. This novel Baeyer-Villiger monooxygenase (BVMO) shows a similar substrate specificity and selectivity when compared with the protot...

The extraction of lithium from salt lake brine in the Chinese Qaidam Basin is challenging due to its high Mg/Li and Na/Li ratios. Herein, we utilized a reaction-coupled separation technology to separate sodium and lithium ions from a high Na/Li ratio brine (Na/Li = 48.7, w/w) and extracted lithi...

Raman spectroscopy and high-sensitivity differential scanning calorimetry (DSC) were used to compare the effects of headgroup conformation on the acyl chain packing arrangements in two highly asymmetric phosphatidylcholine (PC) analogues 1-stearoyl-2-capryl-sn-glycero-3-phosphocholine (C(18) : C...

Both (R)- and (S)-pipecolic acids and their 2-alkyl derivatives have been synthesized via diastereoselective alkylations of (R)-5-phenylmorpholin-2-one 5.

We have studied the leukotriene antagonistic activity of a novel compound, SR2640 (2-[3-(2-quinolylmethoxy)phenylamino]benzoic acid), in vitro and in vivo. SR2640 inhibited LTD4− but not histamine-induced contractions of guinea-pig ileum and trachea in a concentration-dependent manner. Schild pl...

Molecular modelling of leukotriene CysLT1 receptor antagonists have suggested that in addition to the two binding sites for a lipophilic and an acidic group, the receptor has a ‘third pocket’ to accommodate ‘three-armed’ ligands such as montelukast 1. Based on the most rigid CysLT1 receptor ...

The specific control of adrenal androgen secretion is unclear. This study was undertaken to investigate the effects of peptides derived from the ACTH precursor molecule pro-opiomelanocortin (POMC) on cortisol and androgen production using isolated guinea-pig adrenal cells. ACTH 10−13−10−9M, stim...

The molecular forms of proopiomelanocortin (POMC) derived amidated and C-terminal glycine-extended joining peptide from monkey (Macaca mulatta) pituitary were determined. The predominant forms of joining peptide found were the low molecular peptides POMC(76–105) and POMC(76–106), respectively....

The present results report for the first time a systematic study of the effect of arbutin on the dipole potential of lipid membranes. The dipole potential and the area per lipid were measured in monolayers of dimyristoylphosphatidylcholine (DMPC), 1,2-di-O-tetradecyl-sn-glycero-3-phosphocholine ...

Sulfamoylated derivatives of the endogenous estrogen metabolite 2-methoxyestradiol (2-MeOE2 (7)), such as 2-methoxy-3-O-sulfamoyl estrone (2-MeOEMATE (1)), display greatly enhanced activity against the proliferation of human cancer cells and inhibit steroid sulphatase (STS), another current onco...

As current toxoplasmosis chemotherapies have many side effects along with toxicity on patients, we examined the anti-Toxoplasma effect of a biologically important natural antibiotic, kojic acid, in vitro and in vivo. Vero cells were incubated with different concentrations of kojic acid or pyrime...