Acidity and ORP of electro-activated potassium acetate and potassium citrate with and without KCl was studied and the effect of these solutions on spores of C. sporogenes was evaluated at ambient temperature. The ORP and amount of formed acid were proportional to the intensity of the applied ele...
Combined effects of moderate temperatures and the electro-activated aqueous solutions of potassium acetate and potassium citrate on the inactivation of C. sporogenes PA 3679 spores (D121°C = 1.18 min) were studied. Four types of solutions (potassium acetate with/without KCl and potassium citrat...
A novel strategy for the synthesis of hierarchical porous carbons (HPCs) from resol by potassium acetate activation for advanced supercapacitor electrodes was reported.The resultant HPCs with a high specific surface area up to 1201 m2 g−1 as a supercapacitor electrode exhibits a high specific ca...
Potassium acetate was intercalated into metakaolinite by grinding. The effect of grinding time, potassium acetate content and heat was investigated by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), thermal analysis (TG–DSC) and transmission electron microscopy (TEM). T...
Potassium acetate (KAc) has been successfully intercalated into dickite through immersion method. Prepared complexes were characterized by XRD, FTIR, TG-DTA, XPS and SEM-EDS analyses. The effectiveness of intercalation and influencing factors were also analyzed. The results confirmed that KAc an...
Hydroxyurea is an antitumoral drug mainly used in the treatment of Philadelphia chromosome-negative myeloproliferative syndromes and sickle-cell disease. Ulcers represent a rare but severe long-term adverse effect of hydroxyurea therapy.Hydroxyurea-induced ulcers are often multiple and bilateral...
We conducted the first nation-wide cohort study of sickle cell disease (SCD) in Italy, a Southern European country exposed to intense recent flux migration from endemic areas for SCD. We evaluate the impact of hydroxyurea on a total of 652 pediatric and adult patients from 33 Reference Centers f...
A 59-year-old African American female presented to a plastic surgery office in consultation for a very painful non-healing wound of her right lateral malleolus. An incisional biopsy was performed and ultimately a diagnosis of hydroxyurea-induced ulcer was concluded. Descriptions of this entity a...
Ischemic injury is a primary contributor to the initiation of renal tubular epithelial cell damage in sickle cell disease (SCD). In this study, we investigated the effects of bilateral ischemia-reperfusion injury, which is a common type of acute kidney injury (AKI), in male and female genetic mo...
The limited flexibility and time-consuming nature of the genetic manipulation procedures applicable to Trypanosoma cruzi continue to restrict the functional dissection of this parasite. We hypothesised that transformation efficiency could be enhanced if electroporation was timed to coincide with...
Aneuploidy refers to aberrancies in cellular chromosome count, which is prevalent in most human cancers. Chemotherapy is an effective cancer treatment; however, the development of drug resistance is a major concern of conventional chemotherapy. The chemotherapy agent hydroxyurea (HU) targets pro...
Hydroxyurea is a potent disease-modifying therapeutic agent with efficacy for the treatment of sickle cell anemia. When administered at once-daily oral doses that lead to mild marrow suppression, hydroxyurea leads to substantial and sustained fetal hemoglobin induction, which effectively inhibit...
Hydroxyurea, a ribonucleotide reductase inhibitor, is a potent teratogen in mice, causing severe limb and skeletal defects. The exposure of gestation day nine murine embryos to hydroxyurea elicits an early embryonic stress response that involves activation of the P53 transcription factor. The im...
BackgroundHydroxyurea reduces complications and improves health-related quality of life (HRQOL) in sickle cell disease (SCD) patients, however adherence remains suboptimal. Understanding patients’ views of hydroxyurea is critical to optimize adherence, particularly in adolescents and young adul...
ObjectiveTo evaluate the impact of an initiative to increase hydroxyurea use among children with sickle cell anemia (SCA) who presented to the emergency department (ED).
Certain oximes form nitric oxide upon reaction with 4-phenyl-1,2,4-triazole-3,5-dione (PTAD). The oximes appear to undergo an Alder-ene reaction with the PTAD enophile to form a nitroso intermediate capable of dimerization and/or nitric oxide formation. Upon exposure to oxygen, the nitroso compo...
Cleavage reactions involving the halide-bridged [Pd(μ-Cl)(C2,N-aphox)]2 precursor (aphox = acetophenone oxime) with thioamides, in the 1:2 molar ratio, yielded mononuclear cyclopalladated of the type [Pd(C2,N-aphox)(Cl)(L) {L = thiourea (1); N-methylthiourea (2); N,N’-dimethylthiourea (3); N-p...
Transition-metal or iodine catalyzed transformations of O-acyl oximes to various N-heterocycles are well established. Herein, we report a catalyst free, oxime carboxylate based, three-component condensation method to access mono- and disubstituted pyrimidines. A broad range of substituted pyrimi...
22-Oxocholestanes bearing the oxime functionality in the side chain have been synthesized from diosgenin and evaluated in vivo as anti-inflammatory agents in an acute inflammation mouse ear model, against the commercial glucocorticoid dexamethasone. The final compounds were all regioselectively ...
Acetone oxime acrylate has been synthesized as a new active ester monomer. Free radical polymerization yielded a reactive polymer soluble in various organic solvents, such as chloroform, dioxane, DMSO, acetone, methanol, dichloromethane, DMF, and ethanol. Controlled radical polymerization of ace...
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View