Gadolinium is useful in the room temperature magnetic refrigeration due to its large magnetocaloric effect occurring at temperatures close to room. We predict and represent known phthalocyanine complexes as a new class of paramagnets with a large magnetocaloric effect at the temperatures close t...

A derivative of diethylenetriamine-N,N,N′,N″,N″-pentaacetic acid (DTPA), carrying two catechol functional groups has been synthesised by the reaction between DTPA-bis(anhydride) and 3-hydroxytyramine (dopamine). The ligand DTPA-bis(3-hydroxytyramide), [DTPA(HTA)2], is able to form stable hete...

According to a solution study which showed a selective complexation between N,N′-bis(methylsalicylidene)-2-aminobenzylamine (MSAB) and gadolinium ions, MSAB was used as a sensing element in construction of a gadolinium(III) ion selective electrode. Acetophenon (AP) was used as solvent mediator ...

The initial synthesis of two β-cyclodextrin derivatives bearing seven carboxylate ligands was optimized in order to improve the production of contrast agents. A speciation study using potentiometric analysis was performed on a gadolinium(III) complex. The in vivo myocardic activity was evaluate...

A series of SiO2-La2O2CO3 and SiO2-La2O3 mixed oxide/carbonate systems with La/Si molar ratios of 0.05, 0.1, 0.25, 0.5 and 1.0 have been obtained by the sol–gel technique from tetraethyl orthosilicate (TEOS) and metallic lanthanum powder. For the low lanthanum loading systems (La/Si 0.05 to 0.2...

Modified carbon paste electrode (CPE) and screen printed electrode (SPE) based on ethyl benzoyl acetate (EBA) were prepared and investigated as lanthanum ion selective electrodes. Effect of various plasticizers (o-NPOE, TCP, DBP, DOS, and DOP) and ionophore content was studied. The reaction mech...

Solvent polymeric membranes based on quaternary ammonium salt tridodecylmethylammonium chloride (TDDMACl) with variable concentration of lipophilic inert electrolyte (ETH 500), plasticized with solvents of different nature were investigated by potentiometry and electrochemical impedance spectros...

The double excited state intramolecular proton transfer (ESIPT) mechanisms of porphycene, were theoretically studied. The primary bond lengths, IR vibrational spectra and hydrogen-bond energy indicate that the intramolecular hydrogen bonds were strengthened in the first excited state, which faci...

Computational studies of the structure and electronic spectroscopy of porphyrin and porphycene aggregates has been carried out using Density Functional Theory. A comparison of different DFT approaches has been undertaken, and we show that the proper treatment must include dispersion, here throug...

Antimicrobial photodynamic therapy (APDT) is one of the promising tools for bacteria inactivation, which can be considered as an alternative to the common ways of treatment in the era of growing resistance to antibiotics. Presently applied phototherapeutic agents are often based on porphyrins. P...

A computational model was proposed to evaluate the affinity and selectivity of 2-(3,4-dimethoxyphenyl)ethylamine (homoveratrylamine) imprinted polymers. Four functional monomers: methacrylic acid, 1-vinylimidazole, 4-vinylpyridine, and allylamine were taken into account. Two dielectric constants...

The main objective of this paper was to examined the impact of synthetic reagents on morphology and recognition properties of 2-(3,4-dimethoxyphenyl)ethylamine imprinted polymers. The effect of nine different functional monomers, five porogens and four cross-linkers on the binding capacity of pa...

Publisher SummaryThis chapter discusses the analytical profile of iodoxamic acid. Its generic name is iodoxamate meglumine. Its trade name is endobil, endomirabil, cholovue, and cholegrafin. It is white powder, odorless, with a slightly bitter taste. The ultraviolet spectrum of iodoxamic acid wa...

Efficient syntheses of (2R)-2-Boc-amino-3-phenylsulfonyl-l-propanol 3 and its enantiomer 9 from L-serine are described. The potential of these compounds in a novel general method for the synthesis of optically pure non protein α-amino acids in both the L and D configurations is exemplified by t...

A novel photo-assisted annulation was developed for the synthesis of 6,7-dichloroimidazo[4,5-b]quinolin-2-one. This mild ring closure method has circumvented problems associated with the previous methods and should tolerate a variety of functional groups.

Here we report a novel poly(2-oxazoline)-based block copolymer with the aromatic heterocyclic side chains in one block, poly(2-methyl-2-oxazoline)-b-poly(2-N,N-dimethyl-1,3,5-triazine-2,4-diamine-6-ethyl-2-oxazoline) (PMeOx-PcBOx), and demonstrate its potential application as a drug delivery pla...

A series of novel azacalix[2]arene[2]pyrimidines were synthesized, and evaluated for their antiproliferative activities against A549, MCF7, SH-SY5Y and CNE human cancer cell lines in vitro by using the CCK-8 assay. A number of compounds showed low micromolar antiproliferative activities against ...

Photoexcited o-nitro chromophore in o-nitrobenzylic systems has led to the design and development of many useful photochromic systems such as photolabile protecting groups, photoresists, for controlled release of bioactive compounds, as well as efficient photosynthons giving direct access to man...

Chagas disease is one of the most significant health problems in the American continent. benznidazole (BDZ) and nifurtimox (NFX) are the only drugs approved for treatment and exhibit strong side effects and ineffectiveness in the chronic stage, besides different susceptibility among T. cruzi DTU...

As a part of ongoing studies in developing new potent antimicrobial agents, a series of novel 2-(3-pyridyl)-4,5-disubstituted thiazoles was efficiently synthesized and characterized by spectral and elemental analyses. The newly synthesized compounds were evaluated for their in vitro antimicrobia...