In mycobacteria, the study of inhibition by metal ions has been limited by the absence of suitable molecular vectors. Recently, we reported on the inhibitory activity of a family of chelators, macrocyclic compounds (MCC), against Mycobacterium tuberculosis. In this study equimolar concentrations...
Using indium (III) triflate as a mild Lewis acid catalyst, the Friedel Crafts alkylation of o-hydroxy bisbenzylic alcohols with aromatic/heteroaromatic arenes under solvent free conditions was achieved to give the corresponding unsymmetrical triarylmethanes in high yields (up to 80% yield). Calc...
Waste generated by the electrical and electronic devices is huge concern worldwide. With decreasing life cycle of most electronic devices and unavailability of the suitable recycling technologies it is expected to have huge electronic and electrical wastes to be generated in the coming years. Th...
The growth of whiskers on tin-plated interconnects causes acute short circuit problems and system failures in electronic components. In the past, this problem was suppressed by the addition of a few percent Pb in the electroplated tin, but following the introduction of international laws restric...
This article presents a systematic and extensive review of the syntheses, structures and reactivities of gallium(III) and indium(III) alkoxides and aryloxides. Mono-, bis- and tris(alkoxides) and (aryloxides) have been synthesised and structurally characterised for both gallium(III) and indium(I...
The chlorination process of anhydrous indium(III) oxalate with carbon tetrachloride vapour in an argon stream was studied at different temperatures (200, 250, 300, 350, 400 and 450 °C) and times (5, 10, 15, 20 and 25 h) each. The reaction products were analysed by determination of indium and ch...
A toxicologic and dermatologic review of 2-hexylcyclopentanone when used as a fragrance ingredient is presented. 2-Hexylcyclopentanone is a member of the fragrance structural group Ketones Cyclopentanones and Cyclopentenones. The common characteristic structural element of the group members is a...
Enantiomeric 2-n-hexyl- and 2-n-heptylcyclopentanones (3) and (4) have been synthesized by asymmetric hydrogenation of 2-n-hexylidene and 2-n-heptylidenecyclopentanones (1) and (2) with Ru2Cl4[p-tolyl-binap]2NEt3 complexes. The differences in odor qualities between enantiomeric pairs of the keto...
The 3-(2-adamantyl)pyrrolidines 8a–g, 14 were synthesized and evaluated for activity against influenza A virus. The parent N–H compound 14 was several times more active than amantadine against H2N2 and H3N2 influenza A virus. The combined use of NMR spectroscopy and computational chemistry sho...
Reaction of Me3M (M Al, Ga) with 1-aminoadamantane, Ada, in toluene affords crystalline complexes of the type [Me2M-Ada]2. The gallium compound, I, isomorphous with the aluminum compound, II, crystallizes in the triclinic space group P1 with unit cell parameters a=6.728(1), b=9.957(2), c=10.3...
The ability of a number of nitrogen-containing compounds that simultaneously carry the adamantane and monoterpene moieties to inhibit Tdp1, an important enzyme of the DNA repair system, is studied. Inhibition of this enzyme has the potential to overcome chemotherapeutic resistance of some tumor ...
The present in vitro investigations on amantadine (AmTd) and its isomer 2-aminoadamantane (2-NH2-Adam), and the corresponding analogs, 1-nitroadamantane (1-NO2-Adam) and 2-nitroadamantane (2-NO2-Adam), were undertaken to gain information about molecular features that might have a dominant role i...
Publisher SummaryThis chapter presents the zeolite framework types (nomenclature), composition (chemical and refined), crystal data, reference, powder pattern identification table, simulated powder pattern, and calculated powder diffraction data of {│(C10H17N)4│ [Si64O128]}.
Publisher SummaryThis chapter presents the numerical data and the simulated powder patterns of 1-aminoadamantane Sigma-2 material with zeolite framework type code SGT (recognized by IUPAC Commission on Zeolite Nomenclature) and 9.01° as 2θ value. Two compositions, which are expressed in terms ...
The new 2-alkyl-2-aminoadamantanes and analogues 4–10 were designed and synthesized by simplification of the structure of the potent anti-influenza virus A spiranic aminoadamantane heterocycles 2 and 3. The aim of the present work was to examine the effects of bulky and extended lipophilic moie...
The three-dimensional structure of l-fuculose-1-phosphate aldolase (FucA) from Escherichia coli was determined by X-ray crystallography at a resolution of 2.13 Å. The enzyme is a homotetramer with an Mr of 23,775 per subunit. Since its activity depends on the presence of metal ions (Zn2+) the en...
The crystal structures of l-fuculose-1-phosphate aldolase (FucA) with and without a ligated analogue of dihydroxyacetone phosphate (DHAP) and of a number of active center mutants have resulted in a model of the catalytic mechanism. This model has now been confirmed by structural analyses of furt...
Publisher SummaryThis chapter discusses the determination of L-Fuculose 1-Phosphate aldolase. L-fuculose 1-phosphate aldolase is assayed by determination of dihydroxyacetone phosphate with glycerol 1-phosphate dehydrogenase and reduced diphosphopyridine nucleotide DPNH; the amount of DPNH utiliz...
We report herein a one-pot four-enzyme approach for the synthesis of the rare sugars d-psicose, d-sorbose, l-tagatose, and l-fructose with aldolase FucA from a thermophilic source (Thermus thermophilus HB8). Importantly, the cheap starting material DL-GP (DL-glycerol 3-phosphate), was used to si...
One-pot multistep stereoselective cascade reactions were implemented for the straightforward synthesis of various nitrocyclitols. Two kinases, an aldolase and a phosphatase were involved in this process, together with a spontaneous intramolecular Henry reaction to provide the nitrocyclitol moiet...
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View