A dopamine receptor antagonist, Thioridazine (TDZ) is known for its cytotoxic activity against various cancers and its role in combinational chemotherapy is being actively investigated. Several molecular targets of TDZ have been studied to delineate its anticancer activities, with contrasting fi...

Thioridazine is known to have anti-tumor effects by inhibiting PI3K/Akt signaling, which is an important signaling pathway in cell survival. However, thioridazine alone does not induce apoptosis in head and neck squamous cell carcinoma (AMC-HN4), human breast carcinoma (MDA-MB231), and human gli...

Here, an optical sensor with specific binding sites for sensitive and selective detection of thioridazine hydrochloride (THZ) was prepared. The optosensor was developed based on ZnO quantum dots (QDs) coated with molecularly imprinted polymers (MIPs). Initially, ZnO quantum dots (QDs) were synth...

SummaryThe neurological recovery following traumatic brain injury (TBI) is limited, largely due to a deficiency in neurogenesis. The present study explores the effects of histamine H3 receptor (H3R) antagonism on TBI and mechanisms related to neurogenesis. H3R antagonism or H3R gene knockout all...

Rationale and ObjectivesBased on the definitions in mass category of Breast Imaging Reporting and Data System developed by American College of Radiology, eight computerized features including shape, orientation, margin, lesion boundary, echo pattern, and posterior acoustic feature classes are pr...

Injection of the avermectin analogue, MK-243, into engorged female Amblyomma hebraeum Koch resulted in reduced ovary weight, oocyte length, and ovary vitellin content. There was no significant reduction in hemolymph vitellogenin concentration in MK-243 treated ticks. Although MK-243 was previous...

ResumenObjetivosConocer los valores predictivos y la variabilidad interobservador de los descriptores y de las categorías diagnósticas del sistema BI-RADS- ecografía y su utilidad para predecir la malignidad de los nódulos sólidos mamarios.

Available information pertaining to the nuclear structure of all nuclei with mass numbers A=243 is presented. Various decay and reaction data are evaluated and compared. Adopted data, levels, spin, parity and configuration assignments are given. When there are insufficient data, expected values ...

Rationale and ObjectivesThis study aims to determine the prevalence and predictive value of Breast Imaging Reporting and Data System (BI-RADS) 3, 4, and 5 findings on breast magnetic resonance imaging (MRI) and to evaluate the impact of study indication on the predictive value of BI-RADS categories.

Background & AimsNon-invasive imaging is crucial for the early diagnosis and successful treatment of hepatocellular carcinoma (HCC). Terminology and criteria for interpreting and reporting imaging results must be standardized to optimize diagnosis. The aim of this study was to prospectively comp...

BackgroundThe wide adoption of electronic health record systems (EHRs) in hospitals in China has made large amounts of data available for clinical research including breast cancer. Unfortunately, much of detailed clinical information is embedded in clinical narratives e.g., breast radiology repo...

BackgroundThere are few data regarding the use and outcomes of Breast Imaging Reporting and Data System (BI-RADS) 3 assessment on breast magnetic resonance imaging (MRI). The aim of this study was to describe the imaging findings prompting a BI-RADS 3 assessment and to report their outcomes, inc...

We constructed a high-density genetic linkage map of bronze loquat (Eriobotrya deflexa) for a three-way cross of loquat (Eriobotrya japonica) × (loquat × bronze loquat) by using single nucleotide polymorphism (SNP) markers generated by RAD-Seq, with the combination of simple sequence repeat (S...

Olive oil production involves a significant annual release of industrial olive oil mill effluent to the environment. These discharges bring serious environmental problems since they are extremely hazardous for the aquatic environment due to their organic matter and high turbidity levels. The pre...

While biodiesel production is on the rise, so too is the production of the low-value product, glycerol. Interesterification is an alternative reaction that produces fatty acid methyl esters (FAME) and avoids the production of glycerol. In this work, ferric sulfate is used as a potential heteroge...

Currently available data on toxicological and ecotoxicological endpoints for sulfonic acids have been compiled by the BUA. This compilation reveals a common toxicological profile for the sulfonic acids when all the properties of these substances are taken into consideration. In contrast, the sul...

A high performance environmentally friendly ammonium dinitramide (ADN) based liquid monopropellant was used to develop a thruster with improved performance compared to a conventional hydrogen peroxide propellant microthruster. Compared to regular thrusters, microthrusters have high heat loss due...

A novel nanocomposite adsorbent based on nanosized lanthanum hydroxide doped onto magnetic reduced graphene oxide ([email protected]) was synthesized and used for removal of phosphate and nitrate ions from river and sewage media. The composition, surface properties and morphology of the as prepa...

In this paper, the nanocomposites of reduced graphene oxide/lanthanum oxide are prepared by a simple reflux process. The reduced graphene oxide with a large specific surface area is successfully decorated with lanthanum oxide. The reduced graphene oxide/lanthanum oxide composites are fabricated ...

The potential of hydrothermal technology was utilized for the preparation of promising adsorbents in order to overcome the troubles of methemoglobinemia (blue baby syndrome) and eutrophication which is caused by excess nitrate (NO3−) and phosphate (PO43−) ions in water. Hence, in the present inv...