Several cyanotryptophans have been shown to be useful biological fluorophores. However, how their fluorescence lifetimes vary with solvent has not been examined. In this regard, herein we measure the fluorescence decay kinetics as well as the absorption and emission spectra of six cyanoindoles i...

Three coordination compounds of cobalt(II) acetate with 2-, 3- and 4-aminopyridine were obtained after dissolving Co(CH3COO)2·2H2O and Co(CH3COO)2·4H2O in different solutions of aminopyridines. All three products were characterized magnetically, structurally by single-crystal X-ray diffraction...

Synthesizing one- and two-dimensional arrays of trinuclear chromium(III) basic carboxylate complexes could give rise to new materials with interesting magnetic properties. Trinuclear chromium(III) basic carboxylate complexes where a substituted pyridine ligand could be used to link the trinuclea...

The reaction of 2-chloro-3-oxo-3,4-dihydro-2H-1,4-benzothiazines with ‘push–pull’ enamines was investigated. The reaction with the enamines occurs at the β-carbon atom in the presence of a small excess of triethylamine. As a result, a set of 3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl derivat...

In this work, we report an analysis of the molecular structure and the hydrogen-bonding patterns in the crystal structures of 5-methoxy-2-nitroaniline (1) and 5-methoxy-2-nitroaniline with 2-amino-5-nitropyridine (1:1) co-crystal (2). X-ray single crystal diffraction experiments were carried out...

Various 1-(substituted)-1,4-dihydro-6-nitro-4-oxo-7-(sub-secondary amino)-quinoline-3-carboxylic acids were synthesized from 2,4-dichlorobenzoic acid by six step synthesis. The compounds were evaluated for antimycobacterial in vitro and in vivo against Mycobacterium tuberculosis H37Rv (MTB), mul...

Human African trypanosomiasis is causing thousands of deaths every year in the rural areas of sub-saharan Africa. There is a high unmet medical need since the approved drugs are poorly efficacious, show considerable toxicity and are not easy to administer. This work describes the optimization of...

Three novel series of s-triazine derivatives, including thirty-five new compounds 2a-d, 3a-3p, 4b-d, 5b-d, 6d-6d, and 7a-7f were synthesized comprising a diversity of substituents based on the structure of Astrazeneca arylaminotriazine DNA gyrase B inhibitor. The antimicrobial activity was deter...

3D ligand-based virtual screening was employed to identify novel scaffolds for cannabinoid receptor ligand development. A total of 112 compounds with diverse structures were purchased from commercial vendors. 12 CB1 receptor antagonists/inverse agonists and 10 CB2 receptor agonists were identifi...

Complexes of trimethylsilyl substituted pyridine-2-thiol with rhenium and rhodium have been prepared and structurally characterized. The reaction of methyltrioxorhenium with 3-trimethylsilylpyridine-2-thiol in toluene at 0 °C affords dark green plates of MeReO(η2-2-SC5H3N-3-SiMe3)2) (4). The r...

Para-fluoro-thiol reaction (PFTR) was applied to poly(2,3,4,5,6-pentafluorostyrene) (PPFS) with mercaptopropionic acid (MPA), resulting in a library of carboxylated-PPFS copolymers (PPFS-MPA) differing in their chemical composition. The ability of these COOH-containing derivatives to develop H-b...

For the determination of the in vitro cytochrome P450 activity in microsomes, a quantification method for the probe metabolites, formed during incubation, is required. Due to insufficient sensitivity of a previously developed high performance liquid chromatography–tandem mass spectrometry (HPLC...

A new thiazolylazo reagent, 1-[(5-benzyl-1,3-thiazol-2-yl)diazenyl]naphthalene-2-ol, has been synthesized for the first time. Single crystals of the azo dye were grown from a saturated solution by the vapour diffusion technique. The compound was analyzed using the single-crystal X-ray diffractio...

This paper studied the mechanical properties and durability of plastic mortar made with recycled Polyethylene Terephthalate (PET). The effects of gradation and admixtures, including bitumen, fly ash, and nano-calcium carbonate, on strength were investigated. The temperature stability was studied...

In the present study poly (butylene sebacate-co-terephthalate)s having different compositions were synthesized with a high yield and a random distribution by thermal transesterification of poly (butylene sebacate) and poly (butylene terephthalate) homopolymers. The copolymer with the highest com...

A versatile approach for the modification of polybutylene terephthalate (PBT) surface properties without using solvent, through molten chemical modification of PBT hydroxyl end groups, with n-octyltriethoxysilane is reported. After optimization of the reactional conditions, thermally stable hydr...

Nonisothermal crystallization kinetics of poly(butylene terephthalate) (PBT)/nano calcium carbonate (CaCO3) composites were investigated by differential scanning calorimetry and polarized optical microscopy. PBT/nano CaCO3 composites containing different wt.% of nano CaCO3 were prepared by melt ...

In this paper, the synthesis and properties of poly(1,4-cyclohexanedimethylene-co-isosorbide terephthalate) (PCIT) with isosorbide (IS) content ranging from 16 to 61 mol% relative to the total diols amount were investigated. Amorphous polymers were successfully synthesized without isosorbide rin...

Recent studies have demonstrated the occurrence of microplastic fibers (MFs) in soil environments. To determine whether MFs are harmful for soil biota, we evaluated toxic effects on terrestrial snails (Achatina fulica) after 28 d exposure to polyethylene terephthalate MFs at concentrations of 0....

Grafting polymers bearing active esters, especially pentafluorophenyl methacrylate (PFPMA), onto or from surface is a promising approach towards the preparation of highly functional materials due to the ease in post-polymerisation modification of their corresponding polymers. Herein, a handy and...