In this work, we designed and synthesized two novel bipolar deep-blue emitting materials, 2-(4'-(9H-carbazol-9-yl)-[1,1′-biphenyl]-4-yl)-1 (4(tri-fluoromethyl) phenyl)-1H-phenanthro[9,10-d] imidazole (CzB-FMPPI) and 9-(4'-(4,5-diphenyl-1 (4-(trifluoromethyl) phenyl)-1H-imidazole-2-yl)...

Herein, metal-organic framework (MOF-199) as a nanoporous material was synthesized and characterized using FESEM, EDS, FTIR, XRD, BET and TGA. Basic Blue 41 was used for investigating the photocatalytic activity of MOF-199. The SEM image showed that a nanoporous MOF was synthesized. The effect o...

Blue energy is one of the development sectors identified in the European Union strategic documents within the blue economy that promotes the exploitation of the sea potential. European energy initiatives recognize the importance of blue energy and encourage its research and development. The offs...

Grapevine (Vitis vinifera L.) berry synthesizes and accumulates a large array of phenolic compounds (e.g. flavonoids and hydroxycinnamic acid derivatives), some of which result from acylation mechanisms. In grapevine, the genes encoding enzymes responsible for such acylation are largely unknown....

Aspergillus oryzae was isolated from coffee pulp, screened for the production of carboxypeptidase and confirmed by molecular studies. Coffee pulp posses high protease activity (1.4 × 103 nkat/mL) among the agro-substrates used for the production of proteases but wheat bran was used for further ...

Complement system orchestrates the innate and adaptive immunity via the activation, recruitment, and regulation of immune molecules to destroy pathogens. However, regulation of the complement is essential to avoid injuries to the autologous tissues. The present study unveils the characteristic f...

This study aimed at evaluating an enzymatic strategy to mitigate ochratoxin A (OTA) exposure via contaminated wheat flour. Firstly, the effect of Rhizopus oryzae and Trichoderma reesei, which are both non-toxigenic microorganisms, on OTA, was evaluated. The mycotoxin ​​was degraded by both fungi...

Transmission-blocking vaccines (TBV) interrupt malaria parasite transmission and hence form an important component for malaria eradication. Mosquito midgut exopeptidases such as aminopeptidase N & carboxypeptidase B have demonstrated TBV potential. In the present study, we cloned and characteriz...

Carboxypeptidase B (CPB) is a protease that specifically hydrolyzes C-terminal alkaline amino acid of a peptide, which plays an important role in biological analysis. The activity and inhibition of CPB are significant for peptide sequencing and protein engineering. In this paper, a sensitive and...

Functionally uncharacterized gene Rv3627c is predicted to encode a carboxypeptidase in the pathogen of Mycobacterium tuberculosis (M. tuberculosis), which remains a major threat to human health. Here, we sought to reveal the function of Rv3627c and to elucidate its effects on mycobacterial growt...

Waste conversion into value added materials is a growing subject due to environmental concerns. In the production of orange juice high amounts of orange peel waste are generated and although they are used for the extraction of some extractable compounds a new waste is generated not much differen...

Monocarbides of thorium, ThC and (Th, U)C, are interesting as alternative fertile material to be used in nuclear breeder systems. They have high metal density, high thermal conductivity and wide homogeneous composition range. Specimens were prepared by carbothermic reduction. Vapor pressures of ...

A polycrystalline sample of thallium antimony telluride, TlSbTe2, has been prepared and the thermoelectric properties, such as the electrical resistivity, Seebeck coefficient, and thermal conductivity have been measured. An ultrasonic pulse echo measurement has been performed to evaluate the ela...

SummaryRefractory rare-earth tellurides with the Th3P4 structure type have attracted considerable interest as high-performance thermoelectric materials since the 1980s due to their high dimensionless figure of merit (ZT). Extensive work has been conducted on La3−xTe4 with peak ZT values greater ...

The negative difference effect of pure magnesium and of the alloy AZ91 was investigated by volumetric tests in NaCl with and without addition of Na2SnO3. Hydrogen comes from two sources: H2 which accompanies localized magnesium dissolution inside the pits and H2 from H2O reduction at the passive...

β-Escin, the major active compound in extracts of the horse chestnut Aesculus hippocastanum seed, has shown clinically significant activity in chronic venous insufficiency (CVI). Our previous studies had shown that β-escin sodium inhibited angiogenesis in chick chorioallantoic membrane (CAM) a...

Acetyl kidamycin, an antitumor antibiotic, was strongly bound to DNA in vitro, consequently, the melting temperature of DNA was significantly increased, and its buoyant density was decreased. From these results, it was suggested that acetyl kidamycin stabilized residual links between complementa...

A detailed spectral comparison between kidamycin 1 and hedamycin 13 shows that the two antibiotics have almost identical structures. However, the olefinic side chain at C-2 of kidamycin is replaced in hedamycin by a 2,3,4,5-diepoxy-2-hexyl group.

By means of chemical studies as well as an X-ray analysis of kidamycin (1a), an antitumor antibiotic produced by a Streptomyces species, we have elucidated its structure and stereochemistry. Kidamycin represents a new type of polycyclic C-glycosyl microbial metabolites.

Bispecific monoclonal antibodies can bind two protein targets simultaneously and enable therapeutic modalities inaccessible by traditional mAbs. Bispecific formats containing a heterodimeric Fc region are of particular interest, as a heterodimeric Fc empowers both bispecificity and altered valen...