The synthesis, in vitro calcium channel blocking activities and the affinities for the Ca2+-entry receptor protein, of a new series of diethyl 2,6-dimethyl-4-[2-(ω-substituted-alkoxy)phenyl]- -1,4-dihydropyridine-3,5-dicarboxylates are discussed. Increasing the ω-substituted alkoxy chain lengt...

The alkenyldiarylmethanes (ADAMs) are a class of non-nucleoside reverse transcriptase inhibitors (NNRTIs) targeting HIV-1. Four chemically and metabolically stabilized ADAMs incorporating N-methoxyimidoyl halide replacements of the methyl esters of the lead compound were previously reported. In ...

In this paper, we found a new enhancement fluorescence system La-Tb-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid (or ciprofloxacin, CPFX)-sodium dodecylbenzenesulfonate (SDBS), and the characteristic fluorescence of the La-Tb-CPFX-SDBS system was studied ...

New Hofmann type complexes in the form of M(CyHEA)2Ni(CN)4 (where CyHEA = 2-(1-cyclohexenyl)ethylamine; M = Ni or Co) have been prepared in powder form and their infrared spectra have been reported in the range of 4000–400 cm−1. The thermal behaviour of these complexes has been investigated by ...

New Hofmann-Td- type complexes in the form of Ni(CyHEA)2M(CN)4 (where CyHEA = 2-(1-cyclohexenyl)ethylamine and M = Cd or Hg) have been prepared in powder form and their infrared (4000–100 cm−1) and Raman (2800–1650 cm−1) spectra have been reported. The thermal behaviour of these complexes has ...

New Hofmann type benzene clathrates in the form of M(CyHEA)2Ni(CN)4·2benzene (where CyHEA = 2-(1-cyclohexenyl)ethylamine and M = Ni or Cd) have been prepared in powder form and FT-IR and Raman spectra have been reported. The results suggest that title compounds are similar in structure to Hofma...

FT-IR and 1H, 13C, DEPT, HETCOR, COSY, and NOESY NMR spectra of 2-(1-cyclohexenyl)ethylamine (CyHEA) have been reported for the first time. The vibrational frequencies and 1H, 13C NMR chemical shifts of CyHEA (C8H15N) have been calculated by means of the Hartree–Fock (HF), Becke–Lee–Yang–Par...

The solution properties of a varied group of solutes in di-n-octyl phthalate and di-n-octyl tetrachlorophthalate over the temperature range 60 to 120 °C were studied by gas chromatography. The solvation parameter model was used to assign the contribution of individual intermolecular interaction...

Tertiary amines are effective extractants for separation of carboxylic acids from dilute solutions. The basic principle of recovery by tertiary amines is through reaction with extraction. Generally amines are used in diluents to improves their physical properties and to provide solvation of the ...

The structure and properties of electrochemically synthesized oligomers of the mono n-octyl-ester of 3(3-thienyl)glutaric acid (EGA) have been studied. By using UV-Vis, FT-IR, 1H-NMR, emission as well as simulated UV-Vis and 1H-NMR spectra of the product it has been found that the trimer of EGA ...

BackgroundUnder conditions of oxidative stress, cholesterol aggregates into discrete membrane bilayer domains that precipitate the formation of extracellular crystals, a feature of advanced atheroma in cardiovascular disease. Therapeutic interventions using membrane-directed antioxidants, such a...

Using Langmuir and Langmuir-Blodgett techniques molecular films of chlorinated perylene derivatives, namely tetra-n-butyl-1,6,7,12-tetrachloroperylene-3,4,9,10-tetracarboxylate (PCn for n = 1, 5, 9) have been studied. The Langmuir films of pure compounds and mixed with liquid crystalline 4-octyl...

The present study describes the assimilation of di-n-octyl phthalate by an aerobic bacterium, isolated from municipal waste-contaminated soil sample utilizing di-n-octyl phthalate as the sole source of carbon and energy. The isolate was identified as Gordonia sp. based on the morphological, nutr...

Esters derivatives of alginic acid (Alg) were prepared in carboxylic acid/carboxylic acid anhydrides system by using aqueous perchloric acid as the catalyst. Degree of substitution of hydroxyl group of Alg was estimated to be 2, showing that the hydroxyl group of Alg was fully esterified. Alg ac...

Fatty acid 2-ethylhexyl esters are used for the eco-friendly production of biolubricant. There are several reports on their synthesis, but thermodynamics and transport data of these compounds are lacking. Herein, density and viscosity of palmitic acid 2-ethylhexyl ester, stearic acid 2-ethylhexy...

Protocatechuic acid is used extensively in pharmacological and related industries which can also be obtained by fermentation. Reactive separation by means of reactive extractant is a favourable alternative to recover carboxylic acids from the aqueous dilute streams and the fermentation broth. In...

In this paper, moxifloxacin hydrochloride molecularly imprinted polymer was used as a selective sorbent for solid phase extraction of moxifloxacin hydrochloride from different matrices. First a computational study was conducted for confirming the optimum composition of the polymer to be used as ...

Monomeric Cu(II) complex of bis{2-[(pyridin-2-yl)methoxy] naphthalen-1-yl}methane (L) having a composition, {[Cu(L)(H2O)(ClO4)](ClO4)(CH3OH)2} (1) has been synthesized and characterized by analytical, spectral and magnetic methods and the structure has been established for the first time based o...

In the present study, a series of fourteen 5-benzoyl-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one derivatives were designed, synthesized and characterized by appropriate spectral analysis. Further, titled compounds were in-vitro screened against wild HIV-1 RT enzyme using ELISA based c...

Although 5-(2-aminopropyl)benzofuran (5-APB) and 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one (phenazepam) are being used as recreational drugs, research on their dependence liability or mechanisms of action is lacking. The present study aimed to evaluate the behavioral effe...