Fish oil is a sustainable, abundant, and low-cost raw material, as it is extracted from fish processing waste. This work suggests that fish oil is appropriate for biodiesel production and evaluates its potential through ethyl esters (EE). Initially, fish oil showed an acid value of 10.86 ± 0.05...

A series of 1-acetyl/propyl-3-aryl-5-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-pyrazolines were synthesized in one step by condensing suitably substituted propenones, hydrazine and acetic/propionic acid. The newly synthesized pyrazolines were characterized by analytical and spectral data. T...

New quinolonyl diketo acid compounds bearing various substituents at position 6 of the quinolone scaffold were designed and synthesized as potential HIV-1 integrase inhibitors. These new compounds were evaluated for their antiviral and anti-integrase activity and showed inhibitory potency simila...

Two series (para- and meta-substituted) of racemic methyl esters of 3-aryl-3-hydroxypropionic acid were prepared after which the enantiomers were separated by an enzyme-catalyzed transesterification. Several lipases were investigated as the catalyst. The influence of the enzyme pretreatment, as ...

1-O-cis-Cinnamoyl-β-d-glucopyranose is one of the most potent allelochemicals that has been isolated from Spiraea thunbergii Sieb by Hiradate et al. It derives its strong inhibitory activity from cis-cinnamic acid (cis-CA), which is crucial for phytotoxicity. By preparing and assaying a series ...

Trifluoroacetic acid has been discovered to be a highly effective and efficient reagent for the tandem Claisen rearrangement and cyclization reaction to yield 3-arylmethylene-3,4-dihydro-1H-quinolin-2-ones from compounds obtained from the SN2 reaction between anilines and acetyl derivatives of B...

We have designed the nitrophenylfurylacryl-substituted benzophenone 4f as a non-thiol farnesyltransferase inhibitor utilizing a novel aryl binding site of farnesyltransferase. Variation of the 2-acylamino substituent at the benzophenone core structure of our initial lead 4f yielded several non-t...

Ring opening reactions of 1 with copper complex formed between Cu, TMEDA and BrCF2CO2Et lead to optically active 4,4-difluoroglutamic acid derivatives 11a-d in moderate yields. Reaction of cyclic sulfamidates 1 with fluoro substituted arylmagnesium chlorides proceed via copper catalyzed 1,4-addi...

A group of (E)-3-(4-methanesulfonylphenyl)acrylic acids possessing a substituted-phenyl ring (4-H, 4-Br, 3-Br, 4-F, 4-OH, 4-OMe, 4-OAc, and 4-NHAc) attached to the acrylic acid C-2 position were prepared using a stereospecific Perkin condensation reaction. A related group of compounds having 4- ...

Elevated concentrations of trifluoroacetate (TFA) of more than 100 μg/L in a major German river led to the occurrence of more than 20 μg/L TFA in bank filtration based tap waters. Several spatially resolved monitoring programs were conducted and discharges from an industrial company were ident...

A number of metal trifluoroacetates were reacted with the olefin 3β-acetoxyandrost-5-en-17-one (6). Palladium(II) trifluoroacetate afforded bis[μ-trifluoroacetato(α-5,7-η-3β-acetoxyandrostenyl-17-one)palladium(II)] (20), a new ring B π-allyl steroid–palladium complex, in quantitative yiel...

The role of mercuric trifluoroacetate as reactive agent and activator in reactions of various Se-alkyl phosphoroselenoates with O- and N-nucleophiles is examined. The formation of mercury-complexed intermediates of putative mixed anhydride-like structure is indicated.

Ionic liquids (ILs) have attracted the curiosity of researchers due to their unique properties in different applications such as separation, extraction, purification, catalysis and electrochemical applications. The generation of superoxide ion (O2−) in ILs is one of these interesting areas. In t...

In the present work, solvent-free synthesis of two hydroxyethyl ammonium-based ionic liquids (ILs) at room temperature was carried out namely, N-butyl-(N-hydroxyethyl) ammonium trifluoroacetate ([BHEA][TFA]) and N-butyl-(N-hydroxyethyl) ammonium nitrate ([BHEA][NO3]). The synthesized ionic liqui...

Trifluoroacetate (TFA) is commonly used in a variety of pharmaceutical applications. Because of its toxic nature, it is important to reliably measure the effective removal of TFA. We developed an ion chromatography (IC) method to determine the concentration of residual TFA in samples found in th...

In this study, a group of novel water soluble chitosan ammonium salts with halogens were successfully synthesized, including chitosan-bromoacetate (CSB), chitosan-chloroacetate (CSC), chitosan-dichloroacetate (CSDC), chitosan-trichloroacetate (CSTC), and chitosan-trifluoroacetate (CSTF), and the...

A series of N-SO3H functionalized imidazolium [RSIM][CF3COO] ionic liquids, where R = H, CH3, C2H5 and n-C4H9 were synthesized and fully characterized with spectroscopic techniques. A detailed study on Brönsted acidity, thermal stability, conductivity, density and electrochemical window of the i...

This study shows the design, synthesis and evaluation of eco(phyto)toxic and herbicidal activities of quaternary ammonium salts (QASs), derived from haloacetic acids, in context of the search for safer alternatives to the commonly used herbicide, N-(phosphonomethyl)glycine (glyphosate). The stru...

This research reports an integrated method for synthesizing a quaternary nitrogen-grafted activated carbon that is derived from a subbituminous coal source. The protocol employed nitric acid oxidation, thermal ammonia treatment and methyl iodide quaternization. The quaternized product greatly in...

An effort with the goal of discovering single-dose, long-lasting (>6 months) injectable contraceptives began using levonorgestrel (LNG)-17-β esters linked to a sulfonamide function purposed as human carbonic anhydrase II (hCA 2) ligands. One single analog from this first series showed noticeabl...