An exceptional approach of appending tris(1,10-phenanthroline)cobalt(II)/(III)bis/tris(hexafluorophosphate) and synthesized tetramethyl benzidine-based thiourea derivatives as novel additives with hydroxypropyl cellulose are used to construct a gel polymer electrolyte for DSSC. The thiourea deri...

Highly enantioselective 1, 3-dipolar cycloaddition of 2-arylidene-benzofuran- 3(2H)-ones with imino esters catalyzed by thiourea−quaternary ammonium salts has been developed. This reaction provides efficient construction of a range of chiral spiro[benzofuran-2,3′-pyrrolidine] in high yields (up...

Certain derivatives and analogues of capsazepine are potent in vitro inhibitors of bronchoconstriction in human small airways. During an investigation of the dependency of the potency on the structural features of the capsazepinoids in the thiourea moiety (coupling region) and the 2-(4-chlorophe...

By using a thermogravimetric analyzer, and applying the Clausius-Clapeyron and Langmuir equations, the enthalpies of sublimation and/or vaporization of a set of organic compounds were obtained without determining the vapor pressures of the compounds. Although the Langmuir equation is strictly va...

The standard (p∘ = 0.1 MPa) molar enthalpies of formation, in the crystalline state, of the three thiophenecarboxylic acid derivatives, at T = 298.15 K, were derived from the standard massic energies of combustion, measured by rotating-bomb combustion calorimetry.The Knudsen mass loss effusion ...

Fourteen novel amino-quinoline-5,8-dione derivatives (6a-h and 7a-h) were designed and synthesized by coupling different alkyl- or aryl-amino fragments at the C6- or C7-position of quinoline-5,8-dione. All target compounds showed antiproliferative potency in the low micromolar range in both drug...

Coupling of chiral 1-O-benzylglycerol-2,3-bistriflate with trilithiated chiral 2-N-Boc-3-phenylsulfonylpropan-1-ol derivative constitutes an efficient route to chiral C-5 substituted prolines which can potentially induce cis Xaa-Pro peptide bond conformation. A straightforward seven-step synthes...

A novel series of 6-hydroxy-4-methoxy-3-methylbenzofuran-7-carboxamide derivatives featured with various C-2 substituents were designed and synthesized as Mnks inhibitors through fragment-based drug design. Among them, 5b, 5i, 5o and 8k showed the best Mnk2 inhibitory activity with IC50 values o...

The first enantioselective synthesis of a carbocyclic analogue of showdomycin, 3-[(1S,2S,3R,4R)2,3-(isopropylidenedioxy)-4-(pivaloxymethyl)cyclopentyl]maleimide 1, has been accomplished using the asymmetric Diels-Alder reaction of the (Ss)-3-(2-pyridylsulphinyl)acrylate 2 with cyclopentadiene as...

Poly(2-amino-4-thiazoleacetic acid)/multiwalled carbon nanotubes modified glassy carbon electrodes obtained by electropolymerization of 2-amino-4-thiazoleacetic acid, were used for the voltammetric determination of copper ions. The voltammetric response of copper ions at poly(2-amino-4-thiazolea...

The supersonic expansion of a mixture of the title molecule (TDMAE) with argon generates a beam carrying a log-normal distribution of TDAME(Ar)n clusters, broadly centered at n̄≈60. The femtosecond pump–probe technique is used to investigate the excited state dynamics of these clusters up to a...

X-ray crystal structures of acetylcholine binding proteins (AChBPs) have revealed two different possible extensions to the classical ligand binding pocket known to accommodate various nicotinic agonists. One of the pockets is limited in size while the other is of considerable dimensions and prot...

In our previous paper (Drug Metabolism Parmacokinet 31: 363, 2016), a simulation system for ligand interactions of human CYP1A2 was developed using “Template” composed of hexagonal grids focusing on polyaromatic hydrocarbons (PAHs). The system has been expanded for the application of non-PAH c...

Reported herein is the FeCl3-promoted intermolecular sulfoesterification of o-(1-alkynyl)benzoates with disulfides, which provides a convenient and efficient method for synthesis of 4-sulfenylisocoumarins. Various functional groups such as methoxy, halides, ester, cyano and silicon groups in the...

Enaminones are a novel group of compounds some of which possess anticonvulsant activity in in vivo animal models of seizures. We recently reported that some enaminones, including methyl 4-(4′-bromophenyl)aminocyclohex-3-en-6-methyl-2-oxo-1-oate, depress glutamate-mediated excitatory synaptic tr...

The title compound, 2-(4-bromophenyl)-2-oxoethyl 3-methylbenzoate, has been synthesized and characterized using experimental FTIR, 1H and 13C NMR, single crystal XRD and various theoretical methods (FTIR, NMR, electronic and band gap studies). The compound crystallizes in monoclinic space group ...

The major diesel consumption is in the field of automobile, industry and agriculture. The increasing the petroleum cost also increasing the other consumable cost, it affects the economics of growing country like India. Biodiesel is considered as a promising alternative to fossil fuels worldwide....

MgAl-hydrotalcites (HT) containing 1–2% of the lanthanide ions La3+, Ce3+ and Lu3+ were evaluated as heterogeneous catalysts in the transesterification process for fatty acid ethyl ester (FAEE) synthesis in order to understand the effect of the high ionic-radii of these metals in the material s...

Medium-chain fatty acid (MCFA) ethyl esters, as yeast secondary metabolites, significantly contribute to the fruity aroma of foods and beverages. To improve the MCFA ethyl ester content of wine, mixed fermentations with Hanseniaspora uvarum Yun268 and Saccharomyces cerevisiae were performed. Fin...

Biodiesels, composed of saturated fatty acid alkyl esters (FAAE), have relatively high cloud points (CP), which limit their commercial application. However, fatty acid ethyl esters (FAEE) have potentially advantageous properties, including those related to cold flow, compared to their methyl ana...