Nanosized 1-[(4-methyl-2-nitrophenyl)azo]-2-naphthalenol (C.I. Pigment Red 3) particles were prepared using a facile liquid precipitation method. The morphology and electrical properties of the produced particles were characterized by SEM, ζ-potential and electrophoretic display device. The par...

Serine plays critically important roles in tumorigenesis. Homo sapiens 3-phosphoglycerate dehydrogenase (PHGDH) catalyzes the first committed step for the synthesis of glucose-derived serine via the phosphoserine pathway and has been associated with a wide variety of cancers, including breast ca...

Imidazo[1,2a]pyridines have gained much interest in the field of medicinal chemistry research. In the aim of accessing new privileged structure, we decided to design and synthesize 8-aminated-imidazo[1,2a]pyridines substituted on positions 2 and 6. This scaffold, rarely found in the literature, ...

Herein, we synthesized a series of twelve benzoxazole and benzothiazole derivatives incorporated with phthalimide core as anticancer agents. The most active compounds were 5a and 5g against HepG2 and MCF7 cell lines with IC50 = 0.011 and 0.006 μM, respectively.They evaluated against EGFR and HE...

A novel atom economical diastereoselective synthesis of 5-iminooxazolines and their subsequent transformation to α,α-disubstituted dipeptide esters is described. Heating a mixture of cyclohexyl isocyanide and Z-α-benzoyl amino-acrylic acid alkyl esters under solvent-free conditions, afforded ...

In this work, the title molecule, 7-Methyl-3-[(3-methyl-3-mesityl-cyclobutyl]-5-phenyl-5H-thiazolo[3,2-α]pyrimidine-6-carboxylic acid ethyl ester (C30H34N2O2S1), was synthesized and characterized by FT-IR spectroscopy and single crystal X-ray diffraction. The compound crystallizes in the tricli...

A general and efficient method for the synthesis of 1-substituted 3-amino-1H-1,2,4-triazoles has been developed. The desired 3-amino-1H-1,2,4-triazoles (3) were prepared in good to excellent yields from ethyl N-(5-phenyl-1,2,4-oxadiazol-3-yl)formimidate (1a) and anilines or amines (2) via a one-...

The structural characterization of chiral nylon-3 derivative, poly (3-ethyl-3-phenyl-2- azetidinone) (PEPA) has been carried out using FTIR, thermal analysis, X-ray diffraction and electron microscopy. X-ray diffraction of power and fiber samples were analyzed together with electron diffraction ...

The synthesis of several 3-bromo-4-alkylamino-N-alkyl-1,8-naphthalimides is described. These compounds have been shown to be effective, non-oxygen based photochemical inactivators of enveloped viruses, including herpes simplex virus and HIV.

Bu3SnH-mediated radical cyclization of α-bromo amide 8, bearing phenyl and phenylthio substituents at the terminus of the N-vinylic bond, proceeded in a 4-exo-trig manner to give β-lactam 9. Ruthenium tetroxide oxidation of the phenyl group incorporated into the product 9 provided a new synthe...

Within the olfactory bulb, neurons and their axonal connections are organized into distinct layers corresponding to different functionalities. Here we demonstrate that transcription factor AP-2ɛ is required for olfactory bulb development, specifically the establishment of appropriate neuronal la...

Some copper(II) complexes of the type [Cu(L1–3)(phen]⋅CH2Cl2 (1a–3a) and [Cu(L1–3) (bipy)]⋅CH2Cl2 (1b–3b) (where L1 = N-(2-{[(2E)-2-(2-Hydroxy-benzylidene)-hydrazino]carbonyl}phenyl)benzamide, L2 = N-(2-{[(2E)-2-(2-Hydroxy-(5-bromo)-benzylidene)-hydrazino]carbonyl}phenyl)benzamide, L3 = N-(2...

Sodium nonatitanate powder is a layered material containing some potential exchangeable sodium ions between layers. In this work, sorption mechanism of this material has been studied and modeled at the solid-liquid interface. In particular, the ion-exchange mechanism is up to now not entirely kn...

In the present study, the preparation of strontium hexaaluminate/ZTA composites via a solid-state reaction was carried out. The effect of 10–40 mass% SrAl12O19 on the microstructure, physical and mechanical properties of the SrAl12O19/ZTA composite were addressed. X-ray diffraction (XRD) analys...

A sample of strontium nitrite has been synthesised and thermally characterised to investigate its role in the ageing of magnesium–strontium nitrate pyrotechnic compositions in the presence of water vapour. Studies by isothermal microcalorimetry show that the addition of strontium nitrite to a 5...

The issue of obtaining heterostructures from strontium bismuthate and strontium carbonate is discussed. Effect of increase of photocatalytic activity of such heterostructures at the certain weight ratio of strontium carbonate is discovered. It is shown that increase of photocatalytic activity is...

A new strontium nitrate hydrate SrNO3(OH)·H2O has been synthesized by hydrothermal method. The title compound crystallizes in Pbca (no. 61) with the lattice parameters a = 9.801(5), b = 6.179(3), and c = 14.355(7) Å (Z = 8). Isolated NO3 anionic groups are combined through the SrO9 polyhedra to...

A novel anode candidate, Sr(NO3)2, has been studied as a potential host material in lithium-ion batteries. The phase composition, particle morphology and lithium storage capability of Sr(NO3)2 have been thoroughly investigated. Sr(NO3)2,could maintain its reversible charge capacity at 237.3 mA h...

The methacrylamide monomer, N-(p-bromophenyl)-2-methacrylamide (PBPMA) was synthesized by reacting p-bromoaniline dissolved in ethylmethylketone (EMK) with methacryloyl chloride in the presence of triethylamine. The copolymers of PBPMA with N-Vinyl-2-pyrrolidone (NVP) were synthesized by free ra...

ClGa 5,10,15,20-Tetrakis (4-bromophenyl) porphyrinato (ClGaTBrPP) and its metal free derivative were successfully synthesized and incorporated into Pluronic F127 polymeric micelles that has been conjugated to folic acid (FA) to form ClGaTBrPP-F127-FA (or H2TBrPP-F127-FA). For comparison, ClGaTBr...