The potential of pennywort (Hydrocotyle vulgaris) for phytoremediation of C.I. Acid Blue 92 (AB92) was evaluated. The effects of various experimental parameters including pH, temperature, dye concentration and plant weight on dye removal efficiency were investigated. The results showed that the ...

C.I. Acid Blue 78 is an important acid dye; its manufacture depends on 1-nitroanthraquinone and all procedures developed for the mononitration of anthraquinone give by-products such as dinitroanthraquinones. This paper presents a new method for the manufacture of C.I. Acid Blue 78 in high yield ...

N-(α-Ketoacyl)anthranilic acids were prepared by oxidative ring opening of 3-hydroxyquinoline-2,4(1H,3H)-diones by using paraperiodic acid (H5IO6) or sodium periodate (NaIO4). The optimisation of the reaction conditions is described as well as the utilisation of N-(α-ketoacyl)anthranilic acids...

Thermolysis of 8-hydroxylamino-6-methoxyquinoline at 65° in methanol gave 8-amino-5,8′-iminobis(6-methoxyquinoline), the same product being formed by thermolysis of 8-azido-6-methoxyquinoline as well as by deoxygenation of 6-methoxy-8-nitroquinoline with triethylphosphite in the presence of 8-...

A novel, simple and practical method for the regioselective halogenation of fused heterocyclic N-oxides has been developed. It employs Vilsmeier reagent, generated in situ by POX3 and DMF, as both the activating agent and the nucleophilic halide source. The method is amenable across a broad rang...

The standard (po=0.1MPa) molar enthalpies of formation, at T=298.15K, were determined using static-bomb calorimetry for crystalline 6-methoxyquinoline N-oxide (6MeOQUINO), as −(85.6±3.7)kJ·mol−1 and liquid 6-methoxyquinoline (6MeOQUI), −(25.8±2.2)kJ·mol−1. The standard molar enthalpies of su...

There is an urgent need for new antimalarial drugs with novel mechanisms of action on novel targets. Indolone-N-oxides (INODs) display antimalarial properties in vitro and in vivo, but identified leads such as 6-(4-chloro-phenyl)-5-oxy-[1,3]dioxolo[4,5-f]indol-7-one 1, suffer from very poor aque...

Nitric oxide (NO), a ubiquitous gasotransmitter which plays critical roles in cardiovascular, nervous, and immune systems related diseases, is closely related in the physiological and pathological processes of mitochondria and lysosomes. Thus, monitoring NO in mitochondria or lysosomes is very m...

The synthesized Schiff base, 4-[(4-Hydroxy-3-fluoro-5-methoxy-benzylidene)amino]-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one (I), has been characterized by 13C NMR, 1H NMR, 2D NMR (1H–1H COSY and 13C APT), FT-IR, UV–vis and X-ray single-crystal techniques. Molecular geometry of the compoun...

The purpose of this research is to investigate the viability and efficiency of 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine (MPPOE) as a non-toxic organic inhibitor of mild steel corrosion in oilfield acidizing environment at simulated surface to down-hole tempe...

Transient receptor potential melastatin 2 (TRPM2), a Ca2+-permeable cationic channel, plays critical roles in insulin release, cytokine production, body temperature regulation and cell death as a reactive oxygen species (ROS) and temperature sensor. However, few TRPM2 inhibitors have been report...

Fatty acid binding protein 4 (FABP4) plays a critical role in metabolism and inflammatory processes and therefore is a potential therapeutic target for immunometabolic diseases such as diabetes and atherosclerosis. Herein, we reported the identification of naphthalene-1-sulfonamide derivatives a...

A convenient method for the synthesis of 3-acylpyrazoles and pyrazole-3-carboxylates using diazosulfone as a reactive 1,3-dipole and a diazomethane equivalent is reported here. Chalcones, arylidenemalonates and other arylidene-1,3-dicarbonyls performed well as the dipolarophiles in the reaction ...

Amyotrophic lateral sclerosis and frontotemporal lobar degeneration are incurable motor neuron diseases associated with muscle weakness, paralysis and respiratory failure. Accumulation of TAR DNA-binding protein 43 (TDP-43) as toxic cytoplasmic inclusions is one of the hallmarks of these patholo...

Human exposure to N,N-diethyl-m-toluamide (DEET) occurs because of the widespread use of DEET as an active ingredient in insect repellents. However, information on the extent of such exposure is rather limited. Therefore, we developed a fast on-line solid phase extraction–high performance liqui...

The photochemical transformation of N,N-diethyl-m-toluamide (DEET), one of the most widespread and efficient mosquito repellents, has been investigated. Initially, photoinduced DEET degradation was investigated in liquid samples, at 20 °C and 0 °C, and in ice (−15 °C), aimed to simulate all p...

Analytical and electron paramagnetic resonance (EPR) spectroscopic methods were systematically used for the kinetic and mechanistic investigation of the photocatalytic degradation of N,N-diethyl-m-toluamide (DEET), in aqueous TiO2 suspensions under simulated solar light. The degradation of DEET ...

The paper deals with the aqueous environmental fate of N,N-diethyl-m-toluamide (DEET), one of the most widespread and efficient mosquito repellents. The investigation involved monitoring of the DEET decomposition and the identification of intermediate compounds.Initially, control experiments in ...

This study investigates the electrochemical oxidation of N,N-diethyl-m-toluamide (DEET) on a boron-doped diamond (BDD) anode under different temperatures, current densities, and sample matrixes. For comparison, a commercial Pt electrode and a lab-prepared PbO2 anode were also tested. The oxidati...

Due to the inhibition of β-oxidation, radiolabeled long-chain fatty acids with substituents in the alkyl chain often can enhance the retention of myocardial radioactivity. In this connection the synthesis and biodistribution of 12 new radioiodinated ω-(p-iodophenyl) fatty acids is described fe...