Cyclic voltammetry and controlled-potential (bulk) electrolysis have been used to characterize the behavior of a structurally modified nickel(I) salen species, that can be electrogenerated at carbon cathodes in dimethylformamide (DMF) containing 0.10 M tetra‑n‑butylammonium tetrafluoroborate (TB...

The Fourier transform infrared (FTIR) and FT-Raman spectra of 4-chloro-2-methylaniline and 4-chloro-3-methylaniline have been recorded in the range 4000–400 and 4000–100 cm−1, respectively. The complete vibrational assignment and analysis of the fundamental modes of the compounds were carried ...

The influence of structurally related N,O-chelating ligands with additional heteroatoms (N, O, P, S) on the reactivity of in situ generated tantalum complexes for the hydroaminoalkylation of amines has been explored. Reactivity was probed by evaluating the catalytic ability of these N,O-chelatin...

The molecular complex between 1-(2-methoxyphenyl)-1H-imidazole-2(3H)-thione (HmimOMe) and iodine (I2) was investigated. Single crystal of [(HmimOMe)I2] adduct was grown by slow evaporation technique from chloroform at room temperature. Spectroscopic techniques such as FT-IR and Raman techniques,...

IR and Raman spectral measurements in the region 3500–400/50 cm−1 have been made for the liquid samples of 2-Methoxyphenyl isocyanate and 2-Methoxyphenyl isothiocyanate. A complete assignment of the measured bands has been proposed as aided by conformational and vibration analyses at B3LYP/6-31...

Pleural fibrosis is associated with various inflammatory processes such as tuberculous pleurisy and bacterial empyema. There is currently no ideal therapeutic to attenuate pleural fibrosis. Some pro-fibrogenic mediators induce fibrosis through inflammatory processes, suggesting that blockage of ...

G protein coupled receptors (GPCRs) produce pleiotropic effects by their capacity to engage numerous signaling pathways once activated. Functional selectivity (also called biased signaling), where specific compounds can bring GPCRs to adopt conformations that enable selective receptor coupling t...

Two new one-dimensional coordination polymers, [Cu(μ-4aepy)2(H2O)2][Ni(CN)4] (1), and [Zn(μ-4aepy)2(H2O)2][Pd(CN)4] (2) [4aepy = 4-(2-aminoethyl)pyridine] have been synthesized and characterized by vibrational (FT-IR and Raman) spectroscopy, single crystal X-ray diffraction, together with the ...

Two inorganic–organic hybrid compounds [(C7H18N2)6Pb7I26] (1) and [(C7H18N2)Pb2I6] (2) have been synthesized by reactions of 2-(2-aminoethyl)-1-methylpyrrolidine and lead iodide with 1: 1 and 1: 2 M ratios in concentrated HI aqueous. The single-crystal X-ray diffraction revealed that the inorga...

The interaction of diethylltin(IV) (DET) and divinyltin(IV) (DVT) with 1-(2-aminoethyl)-pyrrolidine (AEPY) was investigated using potentiometric technique at ionic strength of 0.1 mol dm−3 NaNO3. The hydrolysis constants of diethyltin(IV) and divinyltin(IV) cations and the stepwise formation con...

A series of 1-[[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propyl]piperazine derivatives have been prepared and in vitro tested as H3-receptor antagonists (the electrically evoked contraction of the guinea pig jejunum). It appeared that by comparison of homologous pairs the 1-[[2-thiazol-5-yl-(2-methyl-...

Synthesis and properties of double-stranded RNAs (dsRNAs) and small interfering RNAs (siRNAs) containing 4′-C-aminoethyl-2′-deoxy-2′-fluorouridine are described. Thermal denaturation studies showed that incorporation of 4′-C-aminoethyl-2′-fluoro analog improved the thermal stabilities of ds...

5-Trifluoromethoxy-1H-indole-2,3-dione 3-(N-ethyl/benzylthiosemicarbazone) (2a/2b) and 5-trifluoromethoxy-1-morpholinomethyl-1H-indole-2,3-dione 3-(N-ethylthiosemicarbazone) (3a) were synthesized. The structures of the compounds were confirmed by elemental analysis, spectral data and X-ray singl...

The surface-enhanced resonance Raman scattering (SERS+RRS) spectra of meso-tetrakis(4-N-methylpyridyl)porphine (TMPyP) adsorbed at Ag electrode surfaces were measured at various electrode potentials. The potential dependence of the surface spectra were analysed by comparison with the ordinary re...

Large unilamellar vesicles (LUV) formed by egg phosphatidylcholine (PC) and cholesterol (CL), and containing encapsulated soluble porphyrin H2TMpyP-4 were characterized and studied by light-scattering, freeze-fracture electron microscopy and fluorescence spectroscopy. The inclusion of CL produce...

The base pair selectivity of the intercalative binding of the copper porphyrin, copper (II) tetrakis (4-N-methyl-pyridyl)porphine (Cu(II)TMpyP-4 to DNA has been investigated using a variety of DNA types and the synthetic polynucleotides poly(dG-dC)2 and poly(dA-dT)2. The studies utilize electron...

In situ electrochemical-absorption spectra of meso-tetrakis (4-N-Methylpyridyl) porphine p-Toluenesulfonate (TMPyP) adsorbed on the surface of an ITO (indium–tin-oxide) electrode was observed by simultaneous measurements using cyclic voltammetry (CV) and internal reflection spectroscopy. The CV...

The surface-enhanced resonance Raman scattering (SERRS) spectra of tetrakis(4-N-methylpyridyl)porphine (TMPyP(4)) adsorbed on Ag colloids were measured and compared with the resonance Raman scattering (RRS) spectra of TMPyP(4). The surface spectra evidenced the conversion of the adsorbed porphin...

Surface-enhanced resonance Raman scattering (SERRS) spectra were measured for meso-tetrakis(2-N-methylpyridyl)porphine (TMPyP(2)) adsorbed on silver electrode surfaces from its 1 mol/l HCl solution and compared with the SERRS spectra of meso-tetrakis(4-N-methylpyridyl)porphine (TMPyP(4)). On ads...

ABSTRACTA series of 2-[2-(2,6-dichlorophenyl)amino]benzyl-3-(5-substituted phenyl-4,5-dihydro-1H-pyrazol-3-yl-amino)-6,8-dibromoquinazolin-4(3H) ones 6a-m have been synthesized by the reaction of 2-[2-(2,6-dichlorophenyl) amino]benzyl-3-substituted phenylacrylamido-6,8-dibromoquinazolin-4(3H) on...