Organophosphorus esters (OPEs), a series of high production volume chemicals, receive increasing concerns due to their occurrence in worldwide aquatic environment and resistance to conventional biological water treatment processes. Degradation of tris(2-chloroethyl) phosphate (TCEP) was tested w...

Three CeO2 samples with different morphologies, i.e., cubes, rods, and spindles, were synthesized and investigated for 2-chloroethyl ethyl sulfide (2-CEES) degradation. The samples were characterized using scanning electron microscopy, transmission electron microscopy, X-ray diffraction, X-ray p...

The presence of halogenated organophosphate flame retardants in natural water systems is a widespread concern because of their potential threat to human health and the environment. TiO2 photocatalysis at 350 nm leads to rapid degradation of tris (2-chloroethyl) phosphate (TCEP). The observed deg...

A series of 6-chloro-5-(2-substituted-ethyl)-1,3-dihydro-2H-indol-2-ones (3a-h) and 6-chloro-5-(2-chloroethyl)-3-(alkyl/aryl-2-ylidene)indolin-2-ones (5i-x) were synthesized. Compounds 3a-e, 5i-l and 5q-r were selected by NIH, USA for in vitro anti-proliferative screening. Based on the impressiv...

We initiated our structure-activity relationship (SAR) studies for novel ACC1 inhibitors from 1a as a lead compound. Our initial SAR studies of 1H-Pyrrolo[3,2-b]pyridine-3-carboxamide scaffold revealed the participation of HBD and HBA for ACC1 inhibitory potency and identified 1-methyl-1H-pyrrol...

A convenient new method was developed to prepare two types of vinyl cyclopropane derivatives through gold-catalyzed cyclization of 1-alkynyl cyclopropyl tert-butyl carbonates 2. Different from the previous reported 5-exo-dig route, the 6-endo-dig addition is the preferred pathway to provide six-...

Synthesis of 1,2-dihydroisoquinolin-1-ylphosphonates via CuI-catalyzed three-component tandem reactions of 2-(2-formylphenyl)ethanone, amine, and diethyl phosphite is described. The reactions proceed smoothly under mild conditions leading to the desired products in good yields.

In the past few decades, significant strides have been made in the domain of phytomedicines. Amongst the various medicinal plant taxa exploited for that purpose, orchids are an important representative. Ansellia africana is one such candidate taxon, which has incessantly been used in various her...

The aim of this work was the study of the best conditions for obtaining a callus culture from the pulp of Acca sellowiana, and to perform a quali-quantitative analysis of the secondary metabolites yielded by the in vitro callus culture. To this end, callus was induced on both Murashige and Skoog...

Publisher SummaryThis chapter discusses the formation and stability of dansyl chloride procedure. Dansyl chloride is used for providing fluorescent “handles” for the study of proteins. The reaction of the dye with α-chymotrypsin led them to propose its use as a means of studying the α-amino ...

Aiming at synthesis of nonperiodic sequence-controlled polymers, we have been focusing on copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) polymerization of monomers possessing both azide and alkyne groups. For this purpose, we have chosen N-ethynyl-4-azidobenzenesulfonamide derivatives b...

In this work, the experimental and theoretical vibrational spectra of P-Iodobenzene sulfonyl chloride (P-IBSC) were studied. P-IBSC and its derivatives present in many biologically active compounds. Because of their spectroscopic properties and chemical significance in particular, sulfonyl chlor...

A series of new N-substituted-3-mercapto-1,2,4-triazoles (3a,b and 7a–d), triazolo[1,3,4]thiadiazines (5a,b) and triazolo[1,3,4]thiadiazoles (4a–d, 6 and 8a–d) have been synthesized starting from isonicotinic acid hydrazide. The structure of the newly synthesized compounds was confirmed on th...

ObjectivesThe aim of this study was to determine whether the reduction in peripheral revascularization with vorapaxar in patients with peripheral artery disease (PAD) is directionally consistent across indications, including acute limb ischemia, progressively disabling symptoms, or both.

SummaryBackgroundIncreased D-dimer concentrations are associated with poor cardiovascular and other clinical outcomes in people with treated HIV infection. Proteinase activated receptor-1 (PAR-1) is activated by thrombin and overexpressed by immune cells from HIV-infected people. We aimed to stu...

Sugarcane bagasse (SCB) hydrolysate could be an interesting source for red pigment production by Monascus ruber Tieghem IOC 2225. The influence of different wavelength of light-emitting diode (LED) at 250 μmol.m−2.s−1 of photon flux density on red pigment production by M. ruber in glucose-based...

Some important characteristics of selected pigments have been evaluated, using the inverse gas chromatography (IGC) technique, that indicate the occurrence of preferential interactions in pigmented polymer blends. Attention has been given to copper phthalocyanine pigments and to quinacridone pig...

The red, brown, yellow and green pigment lumps from the Hellenistic pigment production site of the ancient agora of Kos (Dodecanese, Greece) are the focus of this paper. A selection of pigments is examined through a combination of analytical techniques, including SEM-EDS on uncoated samples, X-r...

Several studies have demonstrated that N-substituted aminoacid derivatives exhibit weak anticonvulsant activities in vivo. In the present study, a series of amides of aminoacids structurally related to aminoacetamide have been synthesised and investigated for anticonvulsant activity. Among the m...

Nonylphenols and nonylphenol-ethoxylates were detected in the water and sediment samples from the German Bight of the North Sea. Additionally bis (4-chlorophenyl)-sulfone and linear alkylbenzenesulfonates (LAS) were detected in marine waters. Proof of identification is given by comparison of spe...