Organic–inorganic hybrid coatings were prepared using silane-modified glycidyl carbamate resins and different amine crosslinkers via the sol–gel process. Two different silane-modified glycidyl carbamate resins with 33% and 20% silane modification were prepared. The synthesized resins were cros...

Solid mixtures of ammonium carbamate and bicarbonate originating from the CO2 capture by NH3 in water–ethanol solution were converted into urea by heating to 428 K for 60–90 min. The yield of urea was up to 53% on molar basis. An analogous technique was employed to capture CO2 with 1-aminobuta...

cis-2,3-Cyclopropanated abscisic acid (cis-CpABA) has high photostability and good ABA-like activity. To further investigate its activity and action mechanism, 2S,3S-2,3-cyclopropanated ABA (3a) and 2R,3R-2,3-cyclopropanated ABA (3b) were synthesized. Bioassay showed that 3a displayed higher inh...

A three-step synthesis of cyclopropyl peptides is reported. The protocol involves a consecutive Ugi-4CR/elimination reaction to prepare dehydroalanines followed by a Corey-Chaykovsky cyclopropanation reaction. Peptide-like molecules that resemble some pharmacologically active compounds with a va...

Administration of tridiphane (Tandem, DOWCO 356, 2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane) to male Swiss-Webster mice for 3 days at 100, 250, and 500 mg/kg (ip) resulted in increases in liver weight accompanied by an increase in mitotic index and increases in large particle and mic...

Using two commercial immobilized lipases Lipozyme® TL and Novozym® 435 effective kinetic resolution of several novel 3-aryloxy-1-halogenopropan-2-ols was achieved by acyl transfer reaction in organic solvents, yielding both enantiomers with 89–99% ee. In preparative resolutions carried out in t...

In the present study, the concept of oxime library screening by MS Binding Assays was successfully extended to N-substituted lipophilic pyrrolidine-3-carboxylic acid derivatives in the pursuit of varying the amino acid motif in order to identify new inhibitors for GAT1 and to broaden structure–...

Compared with poly(ethylene terephthalate) (PET), the better gas barrier properties of bio-based poly(ethylene-2,5-furandicarboxylate) (PEF) is usually attributed to the geometric characteristics of asymmetric furan ring. In order to figure out the role of furan ring’s polarity in influencing t...

The formation of 2-vinylfuran from the corresponding 4-oxo-2-hexenal (OHE, a lipid oxidation product) under the catalysis of amino acid were studied. The effects of amino acids, reaction temperature, reaction time, water content, pH, metallic ions and some food additives on the formation of 2-vi...

Nowadays, macroalgae are widely discussed as advantageous alternative feedstock for crude bio-oil production using pyrolysis. In the present work, pyrolysis products of Enteromorpha clathrata washed with 7% phosphoric acid, hydrochloric acid and sulfuric acid were studied. In general, washing wi...

4-Carboxybenzyl sulfamic acid functionalized Fe3O4 nanoparticles as a novel catalyst was manufactured. This catalyst was characterized and evaluated in the one-pot synthesis of furan-2(5H)-one derivatives from dimethyl acetylenedicarboxylate, aryl aldehydes, and various anilines in terms of acti...

A new series of N-substituted derivatives of 2-[(5-{1-[(4-chlorophenyl)sulfonyl]-3-piperidinyl}-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide (6a-w) has been designed and synthesized with multifunctional moieties. The synthesized compounds were evaluated for their antibacterial and anti-enzymatic pote...

BackgroundIschemia-reperfusion injury is an inevitable consequence of kidney transplantation, leading to metabolic acidosis. This study compared the effects of normal saline (NS) and Plasmalyte on acid-base balance and electrolytes during living donor kidney transplantation using the Stewart and...

IntroductionIn multi-level lumbar spinal fusion surgery yielding a large amount of blood loss, choice of fluid for volume resuscitation is an important issue since it can influence acid-base status, coagulation, and patients’ outcome. This study compared the effect of plasmalyte to 0.9% saline ...

A new organic hydrazide derivative crystal, 2-(4-chlorophenoxy)-N′-[(1E)-1-(4-methylphenyl) ethylidene] acetohydrazide (4CP4MPEA) has been successfully synthesized and grown as single crystal from DMF solution. 4CP4MPEA crystallizes in triclinic crystal system with space group P-1 as revealed b...

Psoriasis is a disease state characterized by epidermal proliferation, neutrophil infiltration, along with release of the proinflammatory mediators leukotriene-B4 (LTB4) and 12(R)-hydroxyeicosatetraenoic acid [12(R)-HETE]. LTB4 and 12(R)-HETE are chemoattractant to the neutrophil, the latter app...

Twelve 2,3-dihydro-[1,4]-dioxino[2,3-f]quinazoline derivatives were designed and evaluated as vascular endothelial growth factor receptor 2 (VEGFR-2) inhibitors. The most half-maximal inhibitory concentration (IC50) values of them were less than 10 nM. Among these compounds, 13d displayed highly...

Three quinazolin-4-ylamino derivatives containing phenylbenzenesulfonamides (7a-7c) were synthesized by reacting (E)-N'-(2-cyanophenyl)-N,N-dimethyl formamidine (6) with different 4-amino-N-(phenyl)benzenesulfonamides (4a-4c) and characterized by different techniques such as HRMS, IR, 1H NM...

A variety of novel 1,2-dihydropyridines 10–17, thiophenes 18–21 and thiazole 22 having a biologically active sulfone moiety were obtained via the reaction of 2-cyano-N′-[1-(4-(piperidin-1-ylsulfonyl) phenyl) ethylidene] acetohydrazide 3 with a variety of reagents. The structures of the newly ...

Atomic force microscope (AFM) was used to study the biotoxicity of food preservative sodium benzoate (SB) at the single cellular level. After treatment with SB at different concentrations and interaction time, lymphocyte morphology and membrane ultrastructure were analyzed visually. As compared ...