Starting from an aromatic diamine, 4,4′-(9H-fluoren-9-ylidene)bisphenylamine (FBPA), we have synthesized a series of linear polyimides by polycondensation with different molar proportions of (5,5′-bisisobenzofuran)-1,1′,3,3′-tetrone (BTDA). The polymers were anhydride end-capped or phenylimi...

The anodic oxidation of the title fluorenylidenes in CH2Cl2 + 0.2 M Bu4NBF4 is described. The electrochemical behaviour and the physicochemical properties of the derived polymers are discussed and compared with those of other polymethylenefluorenes.

N,N′-bis(9H-fluoren-9-ylidene)benzene-1,4-diamine was synthesized via the acetic acid-assisted Schiff base reaction between 9-fluorenone and p-phenylenediamine. The thin films were deposited from solution and characterized by contact angle measurements (CAM), X-ray photoelectron spectroscopy (X...

The synthesis, spectral measurements and theoretical study of oligothiophenes terminated by (9H-fluoren-9-ylidene)methyl chromophores at the one (series AN) and both (series BN) ends are presented. The electron absorption and fluorescence spectra of prepared molecules were measured in polymer ma...

N1,N6-Di(9H-fluoren-9-ylidene)hexane-1,6-diamine (DFHD) was conveniently synthesized and characterized, the crystal structure was determined from X-ray single crystal diffraction. The optimized molecular geometry, harmonic vibration frequencies and NMR spectra of DFHD in the ground state have be...

The molecular structure and spectroscopic properties of 1,2-di(9H-fluoren-9-ylidene)hydrazine were studied experimentally by ESI-MS, FTIR, NMR and UV–Vis techniques and computationally by the density functional theory (DFT) method at B3LYP/6-31+G(d,p) level of theory. XRD single crystal showed ...

A series of N-aryl ferrocenylmethanimines was successfully lithiated at ortho-position with the following treatment with various electrophiles such as ketone, alkyl and silyl halides yielding 1,2-disubstituted ferrocenes with good yields. The product of benzophenone addition was characterized wi...

The main antioxidant properties of five new 4-hydroxy-bis-coumarins during bulk lipid autoxidation at 80 °C and 0.1 mM and 1.0 mM concentrations were studied and compared with 4-hydroxy-2H-chromen-2-one (1). These compounds are: 3,3′-((3,4-dihydroxy-phenyl) methylene) bis (4-hydroxy-2H-chromen...

11-Beta-Hydroxysteroid dehydrogenase-1(11β-HSD1) inhibitors are one of the emerging classes of molecules to fight against diabetic complications. A novel series of 4-(1-substituted-1H-1,2,3-triazol-4-yl)-1,4-dihydropyridine derivatives were synthesized and evaluated for their anti-diabetic acti...

A novel library of C2-substituted tryptamines (based on diverse C2-aroyl/arylimino indoles and indole-diketopiperazine hybrids) possessing antimitotic properties were designed, synthesized and screened for their inhibitory activity against tubulin polymerization, and against proliferation of A54...

A series of 3-aryl-4-indolylmaleimide IDH1/R132H inhibitors with a novel structure was obtained by high-throughput screening and structure-based optimization. Most compounds such as 7a, 7d, 7h, 7i, 7k and 7o showed high inhibitory effects on IDH1/R132H and were highly selective against IDH1/WT, ...

ObjectivesDue to various biological activities of sulfonamides, a series of new N-(5-chloro-2-methoxyphenyl)-aryl sulfonamides (3a–e) and their N-benzyl/ethyl substituted derivatives (6a–e & 7a–e) were synthesized followed by antibacterial activity evaluation.

The title compounds, 1-[2-(5-methyl-2-benzoxazolinone-3-yl)acetyl]-3-phenyl-5-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazole (5a) and 1-[2-(5-chloro-2-benzoxazolinone-3-yl)acetyl]-3-phenyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole (5b), were synthesized. The crystal and molecular structures of ...

4-Chloro-N-(2-methoxyphenyl) benzamidoxime (CMB) has been synthesized and characterized by X-ray diffraction, 1H NMR, 13C NMR, FT-IR and FT-Raman spectra. The X-ray study showed that CMB has a Z configuration, due to the strong intramolecular NH⋯O hydrogen bond and centrosymmetric dimer form due...

In the present investigation a series of novel 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles (4a–j) were synthesized by cyclization of substituted-benzoic acid N′-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazole-4-carbonyl]-hydrazide by...

The Fischer indolization of propiophenone (5-chloro-2-methoxyphenyl)hydrazone gives 4-chloro-7-methoxy-3-methyl-2-phenyl-1H-indole and unexpected 6-chloro-3-methoxy-3-methyl-2-phenyl-3H-indole.

Heterocyclic compounds are the most attractive class for researchers due to their biological activities. In the undertaken research, a number of N-(5-chloro-2-methoxyphenyl)-4-(5-substituted-1,3,4-oxadiazol-2-ylthio)butanamide (6a–k) compounds were prepared by converting multifarious phenyl/ary...

Benzoxazoles 2 can be smoothly synthesized by treatment of starting materials of N-(2-hydroxyaryl) cyclopropyl amides 1 with PPh3/CCl4 in acetonitrile in good yields. When PPh3/CBr4/MS 4 Å was used in the reaction system, the corresponding ring-expanding products 3 were obtained in moderate to g...

A novel ferrocene tethered polymer supported ionic liquid phase catalyst has been synthesized and successfully applied for intramolecular O-arylation of o-iodoanilides to corresponding benzoxazoles. The catalyst was easily recovered by simple filtration that greatly simplified the purification s...

2-(2-Hydroxyfluorophenyl)benzoxazole having an imidazole moiety 1 was synthesized by the two step reactions starting from 2-(pentafluorophenyl)benzoxazole. Protonation at the 3-imidazole nitrogen atom of 1 enhances the green emission around 500 nm, where the positive character caused by the prot...